69 results about "Urocystitis" patented technology

To provide a therapeutic or prophylactic agent for frequent urination / strong urge to urinate or incontinence associated with overactive bladder, a lower urinary tract disease accompanied by a lower urinary tract pain such as interstitial cystitis and chronic prostatitis or a disease accompanied by a pain, which acts based on excellent trkA receptor-inhibiting activity. [MEANS FOR SOLVING PROBLEMS] Disclosed is a novel azolecarboxamide derivative having an azole ring (e.g., a thiazole or oxazole ring) bound to a benzene, pyridine or pyrimidine ring through a carboxamide. It is confirmed that the azolecarboxamide derivative has a potent trkA receptor-inhibiting activity. It is found that the azolecarboxamide derivative can be used as a very efficient, safe therapeutic or prophylactic agent for a lower urinary tract disease or a disease accompanied by a pain.

The invention discloses a traditional Chinese medicine for treating urocystitis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 20-30 parts of akebiaquinata, 15-25 parts of semen plantaginis, 30-40 parts of couch grass roots, 10-20 parts of codonopsis pilosula, 10-20 parts of rhizoma atractylodis macrocephalae, 10-20 parts of pericarpium citri reticulatae, 10-20 parts of rhizoma alismatis, 15-25 parts of eucommia ulmoides, 6-12 parts of fructus amomi, 3-7 parts of elecampane, 4-10 parts of cinnamon and 7-15 parts of eclipta alba. The traditional Chinese medicine for treating urocystitis disclosed by the invention takes akebiaquinata and couch grass roots as main medicines matched with other auxiliary medicines and the medicines affect each other, and have a synergistic effect, so that the traditional Chinese medicine has the good functions of promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain and relieving pains, has a good treatment effect to patients with urocystitis, and is safe, free from side effects, simple in preparation method and further convenient to take.

The present invention relates to a phenyl or heteroaryl amino alkane derivatives which are useful as an active ingredient of pharmaceutical preparations. The phenyl or heteroaryl amino alkanes of the present invention have IP receptor antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with IP receptor antagonistic activity. Such diseases include urological diseases or disorder as follows: bladder outlet obstruction, overactive bladder, urinary incontinence, detrusor hyper-reflexia, detrusor instability, reduced bladder capacity, frequency of micturition, urge incontinence, stress incontinence, bladder hyperreactivity, benighn prostatic hypertrophy (BPH), prostatitis, urinary frequency, nocturia, urinary urgency, pelvic hypersensitivity, urethritis, pelvic pain syndrome, prostatodynia, cystitis, or idiophatic bladder hypersensitivity. The compounds of the present invention are also useful for treatment of pain including, but not limited to inflammatory pain, neuropathic pain, acute pain, chronic pain, dental pain, premenstrual pain, visceral pain, headaches, and the like; hypotension; hemophilia and hemorrhage; and inflammation, since the diseases also is alleviated by treatment with an IP receptor antagonist.

An improved method of treating lower urinary dysfunctional epithelium (LUDE) or a disease, condition, or syndrome associated with LUDE, including interstitial cystitis, comprises the step of administering orally a pharmaceutically effective quantity of heparin to a patient in need of treatment for LUDE or a disease, condition, or syndrome associated with LUDE in order to treat LUDE or a disease, condition, or syndrome associated with LUDE. The heparin can be administered together with a quantity of a penetration enhancer that is sufficient to result in a tissue concentration of heparin that is sufficient to treat LUDE or a disease, condition, or syndrome associated with LUDE. A suitable penetration enhancer is sodium N-[8-(2-hydroxybenzoyl)amino]caprylate. The method can further comprise the administration of at least one additional pharmaceutical composition to treat LUDE or a disease, condition, or syndrome associated with LUDE The invention further includes a pharmaceutical composition comprising: (1) a quantity of heparin that is pharmaceutically sufficient for the treatment of LUDE or a disease, condition, or syndrome associated with LUDE; and (b) at least one filler, excipient, or carrier; wherein the pharmaceutical composition is formulated for the treatment of LUDE or a disease, condition, or syndrome associated with LUDE.

Methods and compositions for hydrating cats. Cats fed diets containing certain amounts and ratios of arachidonic acid and eicosapentaenoic acid will be sufficiently hydrated and at reduced risk for development of urinary stones, feline idiopathic cystitis, or FLUTD.

The invention discloses an external application device of traditional Chinese medicine for treating urocystitis. The external application device of the traditional Chinese medicine for treating the urocystitis comprises triangular rear crotch wrapping cloth and triangular front crotch wrapping cloth; a vertex connection position of the rear crotch wrapping cloth and the front crotch wrapping cloth is further provided with a perineum Chinese medicine bag; the rear crotch wrapping cloth is provided with a back binding belt; bilateral sides of the back binding belt are provided with kidney Chinese medicine bags; Chinese medicine compositions are contained in the perineum Chinese medicine bag and the kidney Chinese medicine bags; and the Chinese medicine compositions comprise, by weight, white mustard seed, rhizoma corydalis, kansui root, asarum, fresh ginger, christina loosestrife, dandelion, barbated skullcup herb, lilac pink herb, akebia stem, pyrrosia leaf, wild chrysanthemum, cyperus rotundus and fresh couch grass root. The external application device of the traditional Chinese medicine for treating the urocystitis has the advantages of being simple in structure and convenient to use, being capable of directly dosing diseased regions, being simple in production technology of the built-in Chinese medicine compositions, being wide in source of medicines and low in cost, being capable of clearing damp-heat, treating stranguria and diuresis, nourishing yin and tonifying kidney, activating blood and dissolving stasis, being disinfectant, relieving pain and being obvious in treating effect of urinary tract infection and particularly to lower urinary tract infection (urocystitis).

The present invention discloses one kind of Chinese medicine soft capsule for treating urinary system diseases and its preparation process. The preparation process includes dissolving suspending agent in dispersant, adding Chinese medicine extractum powder and mixing homogeneous to obtain capsule liquid; dissolving gelatin in water, adding glycerin, polyol, iron oxide sodium metabisulfite and ethyl hydroxyl benzoate, mixing homogeneously decompression to debubble to obtain capsule shell; and pressing or dropping to prepare the soft capsule. The Chinese medicine extractum powder is prepared with Cherokee rose root, scabrousstem greenbrier rhizome, Yangkaikou, Jinshateng and centella, and through decoction, filtering, concentrating, drying and crushing. The Chinese medicine soft capsule is used in treating acute and chronic pyelonephritis, acute cystitis, urinary tract infection and other diseases, and has the advantages of high bioavailability, fast absorption, etc.

The invention discloses a medicament for treating pig urocystitis, which is composed of the following bulk drugs: dianthus superbus, fructus kochiae, caulis akebiae, cortex lycii radicis, pollen, rhizoma anemarrhenae, felwort, pericarpium citri reticulatae, radix scutellariae, betel nuts, sanguisorba officinalis, chinaroot greenbier rhizome, cherokee rose roots, sporalygodii, juncus roemerianus, lophatherum gracile, loranthus parasiticus and pyrrosia lingua. The medicament disclosed by the invention has the beneficial effects that due to the adoption of a traditional Chinese medicine composition, the medicament has an obvious curative effect on the treatment of pig urocystitis, and has the advantages of low side effect, high cure rate, short treatment course, uneasiness for relapse, and the like.

The invention discloses a diced bamboo shoot beancurd in wine, which is prepared from the following raw materials in parts by weight: 100-110 parts of soybean, 10-15 parts of sticky rice, 5-6 parts of cauliflower, 5-6 parts of broccoli, 3-4 parts of schisandra chinensis, 1-1.2 parts of polygala tenuifolia, 0.8-1 part of dutchmanspipe root, 5-6 parts of asparagus, 3-4 parts of red dates, 1-2 parts of fresh liquorice, 1-2 parts of radix paeoniae alba, 1-1.2 parts of ligusticum wallichii, 1-1.2 parts of radix notoginseng, 3-4 parts of purple sweet potato, 4-5 parts of winter bamboo shoots, 3-4 parts of tomato sauce, 4-5 parts of red wine, 1-2 parts of brine and 4-5 parts of nutrition additives. The diced bamboo shoot beancurd in wine, disclosed by the invention, is pleasant and delicious; the added bamboo shoot tender stem contains abundant protein, vitamins, mineral substances, trace elements required by a human body, and the like; bamboo shoots contain special asparagine which has a curative effect for cardiovascular diseases, edema, urocystitis and leucocythemia, and also have an anti-cancer effect. In addition, multiple Chinese medicinal herbs are added in a making process, and thus the diced bamboo shoot beancurd in wine has effects of tonifying the spleen and nourishing the stomach, promoting the circulation of Qi and relieving internal heat or fire, and invigorating the spleen and tonifying the Qi.

The invention relates to a medicine composition for treating urocystitis. The medicine composition is characterized by consisting of collagen and a water carrier. The collagen composition solution disclosed by the invention is given in a perfusion manner, therefore, the medicine directionally reaches the surface of the infected cavity (mucosa) of the urinary bladder or patients suffering urocystitis, especially interstitial cystitis, can be used for treating related urinary bladders and is applicable to patents whose lining of the urinary bladder or urethra or lining of the ureter is corroded.

The invention discloses non-boiled fresh cassava-cassava leaf juice and a preparation method thereof, and relates to the technical field of drink processing. The preparation method comprises the following steps: cleaning fresh sweet cassava, removing the outer skin, and breaking into granules of less than 1cm; washing tender fresh cassava leaves, soaking in water for 20-24 hours, and cutting into pieces of less than 1cm; and putting the fresh cassava granules and the cassava leaf pieces into a juice machine, adding water with temperature of higher than 97 DEG C, and stirring at a speed of 30,000 r / min to 32,000 r / min for 4.5-6.5 minutes to obtain the fresh cassava-cassava leaf juice. The fresh cassava-cassava leaf juice prepared by the method is rich in edible fibers, proteins, various vitamins and amino acids, flavonoids compounds, beta-carotenes and various microelements such as calcium, potassium, phosphorus and iron, uniform in nutrition and fine and smooth in mouth feel, has medical health effects of maintaining health of a human body, improving immunity of the human body, preventing cardiovascular diseases, urocystitis and cataract, resisting oxidation and cancers and the like, and is a very good health drink.

The invention relates to a pharmaceutical composition having treating actions for urinary calculus and urinary system infection, which is prepared from the following raw materials and auxiliary materials (by weight ratio): snowbell-leaf tickclover 5-35, chicken's gizzard-skin 2-8, alisol 5-15, amber 1-5, astragalus root 5-15, Japanese felt fern leaf. 5-35, climbing fern spore 2-6, plantain seeds 10-20, and licorice root 1-3, and corydalis ambigua 5-15.

The invention discloses a traditional Chinese medicine composition capable of effectively treating glandular cystitis and a preparation method, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition comprises the following components: gorgon fruits, paris polyphylla, andrographis paniculata, salvia miltiorrhiza, bighead atractylodes rhizomes, houttuynia cordata, dandelion, honeysuckles, kudzu vine roots, radix aconiti carmichaeli, liquorice roots, radix bupleuri, akebia stems and clove. The preparation method comprises the following steps: (1) weighing the raw materials; (2) performing freeze drying treatment; (3) performing corona treatment; (4) performing cryogenic crushing treatment; (5) performing micro-jet high-pressure homogenization treatment; and (6) performing granulating. The traditional Chinese medicine composition prepared by the method can relieve infiltration of epithelial cells and a small amount of lymphocytes and mononuclear cells under mucosa, reduce the degree of capillary hyperemia and edema, remarkably increase the estradiol level of rats suffering from chronic cystitis, increase the expression of ERa receptors, and correspondingly, reduce the expression of the ER beta receptors, so that a remarkable treatment effect on glandular cystitis is achieved.

The invention relates to a medicament for treating hematuria and a preparation method thereof. The medicament is prepared from raw yam, raw fossil fragments, raw oyster, cuttlebone, madder, radices paeoniae alba, the root of Chinese pulsatilla, donkey-hide gelatin and gentian according to certain parts by weight through compatibility. The Chinese medicinal composition disclosed by the invention can replenish and nourish blood, clear away heat and remove toxicity, resist bacteria and inflammation, moisturize dryness and stop bleeding, promote blood coagulation and improve compactness of the vascular wall and has a practical curative effect of treating hematuria caused by tumors of the urinary system, prostatitis, acute cystitis, acute nephritis and kidney or ureteral calculus and particularly hematuria caused by blood diseases. Moreover, the medicament has no toxic or side effects.

The invention discloses an external application device of traditional Chinese medicine for treating urocystitis. The external application device of the traditional Chinese medicine for treating the urocystitis comprises triangular rear crotch wrapping cloth and triangular front crotch wrapping cloth; a vertex connection position of the rear crotch wrapping cloth and the front crotch wrapping cloth is further provided with a perineum Chinese medicine bag; the rear crotch wrapping cloth is provided with a back binding belt; bilateral sides of the back binding belt are provided with kidney Chinese medicine bags; Chinese medicine compositions are contained in the perineum Chinese medicine bag and the kidney Chinese medicine bags; and the Chinese medicine compositions comprise, by weight, white mustard seed, rhizoma corydalis, kansui root, asarum, fresh ginger, ephedra, almond, sargent gloryvine, native achyranthes, cortex lycii radicis, radix angelicae pubescentis, longhairy antenoron herb, common knotgrass herb and black sesame. The external application device of the traditional Chinese medicine for treating the urocystitis has the advantages of being simple in structure and convenient to use, being capable of directly dosing diseased regions, being simple in production technology of the built-in Chinese medicine compositions, being wide in source of medicines and low in cost, being capable of clearing damp-heat, treating stranguria and diuresis, nourishing yin and tonifying kidney, activating blood and dissolving stasis, being disinfectant, relieving pain and being obvious in treating effect of urinary tract infection and particularly to lower urinary tract infection (urocystitis).

The invention discloses a traditional Chinese medicine for treating urocystitis. The traditional Chinese medicine Chinese medicine for treating urocystitis is made of dandelion, polygonum aviculare, verbena, sculellaria barbata, underleaf pearl, creeping oxalis, cordate houttuynia, oldenlandia diffusa, gardenia, folium artemisiae argyi and liquorice according to a certain parts by weight. The medicines are combined, the functions of blood stasis dispersing, lump resolving, stranguria relieving by diuresis, swelling and pain relieving, and heat and toxic materials removing are achieved; for treating the urocystitis, pathology hitting is achieved, symptoms and root causes are both treated, the curative effect is remarkable, relapse does not occur easily, the time on healing duration is short, the compatibility of medicines of the traditional Chinese medicine is simple, the medical herb resource is wide, and the cost is low.

The invention discloses a Chinese medicine oral preparation for treating gynecologic inflammation and its preparation method, wherein the preparation is prepared from 13 Chinese medicinal herb including radix paeoniae rubrathe, burred tuber, toosendan fruit, zedoary, corydalis tuber, gorgon euryale seed, Chinese angelica root, flavescent sophora root, cyperus tuber, Chinese yam,through sorted extraction, concentrating, drying to obtain extract powder, then charging auxiliary material to obtain drop pill or soft capsule.

A nutritional supplement and method of treating or preventing urogenital system disorders including urinary incontinence, overactive bladder, enuresis, benign prostatic hyperplasia, nocturia, cystitis, and urinary calculi, without unwanted side effects. The supplement comprises vitamin D3, nitric oxide precursor, pumpkin seed extract and prebiotic fiber in a particular composition.

The invention discloses an external application device of traditional Chinese medicine for treating lower urinary tract infection. The external application device of the traditional Chinese medicine for treating the lower urinary tract infection comprises triangular rear crotch wrapping cloth and triangular front crotch wrapping cloth; a vertex connection position of the rear crotch wrapping cloth and the front crotch wrapping cloth is further provided with a perineum Chinese medicine bag; the rear crotch wrapping cloth is provided with a back binding belt; bilateral sides of the back binding belt are provided with kidney Chinese medicine bags; Chinese medicine compositions are contained in the perineum Chinese medicine bag and the kidney Chinese medicine bags; and the Chinese medicine compositions comprise, by weight, common anemarrhena rhizome, amur corktree bark, native achyranthes, sargentg loryvine stem, glabrous greenbrier rhizome, unprocessed rehmannia root, white mustard, rhizoma corydalis, gansui root, manchurian wildginger, fresh ginger, cattail pollen, longtube ground ivy herb, fangji root and plantago depressa wild. The external application device of the traditional Chinese medicine for treating the lower urinary tract infection has the advantages of being simple in structure and convenient to use, being capable of directly dosing diseased regions, being simple in production technology of the built-in Chinese medicine compositions, being wide in source of medicines and low in cost, being capable of clearing damp-heat, treating stranguria and diuresis, nourishing yin and tonifying kidney, activating blood and dissolving stasis, being disinfectant, relieving pain and being obvious in treating effect of urinary tract infection and particularly to lower urinary tract infection (urocystitis).

A processing method of a treasurable woman capsule having a formula of radix codonopsis, radix morindae officinalis, herba cistanches and other medicinal herbs is as follows: a slag removal and concentrating method is used for preparation, each kilogram of rhizome of rehmannia is mixed with 2.5 kilograms of wine, a little vinegar is added to boil to remove slag, the liquid is for stand-by use, medicinal materials of plantain herb, Chinese goldthread and honeysuckle are crushed, then boiled with clear water to remove slag, the liquid is for stand-by use; medicinal materials of sheathed monochoria herb, chrysanthemum and cortex moutan are soaked in water for half an hour, then are boiled to remove slag, the liquid is for stand-by use; the three liquids for stand-by use are mixed, the medicinal materials which are in the formula and not used are stirred with the mixed liquids, dried, together ground into powder, sieved with a 180 mesh sieve to prepare the capsule; 4 to 5 grains of the capsule are taken one time, the capsules are taken two times each day, and the course of treatment is 100 days. By taking of the treasurable woman capsule for one month, insomnia, red leucorrhea, cystitis, and the like can be obviously improved; by taking of the treasurable woman capsule for one course of treatment, psychoneurosis and anemia can be treated without recurrence, at the same time, many kinds of gynecological diseases can be regulated, and the treasurable woman capsule can be used for whitening, beautifying, softening and tendering skin.

The invention discloses a decoction for curing cystitis, which comprises the following materials by weight: 5 parts of glabrous greenbrier rhizome, 4 parts of melia azedarach linn, 6 parts of fructus bruceae, 5 parts of flaccid knotweed herb, 3 parts of hylonoma euphorbia root, 5 parts of akebia trifoliata, 5 parts of rhododendron ovatum, 7 parts of rhizoma atractylodis, 4 parts of baical skullcap root, 3 parts of cortex lycii radicis, 4 parts of lotus seed, 7 parts of yam rhizome, 9 parts of dianthus superbus , 3 parts of tamarix chinensis branch, 7 parts of bunge corydalis herb, 3 parts of pyrrosia lingua, 4 parts of lalang grass rhizome, 2 parts of rabdosia and 180 parts of water. The traditional Chinese medicines are placed in a sealed flask after preparation, then heated under 90 DEG C water bath for 3 hours and filtered; the filtrate is collected as the decoction. The decoction has the advantages that the cost is low, the preparation is easy, toxic or / and side effects are low, and the curative effect is obvious.

The invention relates to a traditional Chinese medicine formula, in particular to a Chinese herbal medicine formula for treating lithiasis. The Chinese herbal medicine formula comprises the following raw materials: lysimachia christinae hance, semen plantaginis, lygodium japonicum, dandelion, endothelium corneum gigeriae galli, couch grass root, akebiaquinata, rhizoma cyperi, rhizoma corydalis and honey. The drug properties of the components support one another, so that the traditional Chinese medicine has the efficacies of clearing heat, eliminating dampness, expelling toxin, relieving evil depression, clearing and activating the channels and collaterals, clearing the liver and improving vision, and has a very significant effect on the diseases such as in vivo lithiasis, cholecystitis, urocystitis, urethritis, rheumatic pain and kidney effusion.

The invention relates to the field of traditional Chinese medicines, in particular to a tea bag as well as a preparation method and an application method thereof. The tea bag at least comprises the following components in parts by weight: 2 parts of erythropalum scandens, 2 parts of herb of spicate clerodendranthus, 2 parts of gynostemma pentaphylla, 1.5 parts of radix puerariae, 1 part of lysimachia christinae hance, eucommia ulmoides and 1 part of cichorium intybus. The tea bag disclosed by the invention is a herbal tea bag, has multiple effects of regulating and treating hyperuricemia and concurrent diseases thereof in virtue of one dosage of the tea bag, adopts pure natural raw materials, and is good in curative effect, quick in effect, free of toxic and side effects and capable of regulating and treating gout, diabetes mellitus and concurrent diseases caused by gout and diabetes mellitus, e.g., hypertension, hyperlipidemia, hyperglycemia, hyperuricemia, gallstone, kidney stone, bladder stone, ureteral stone, urethral stone, cholecystitis, hepatitis, nephritis, cystitis, urethritis and adenitis; the tea bag is mixed with water and taken once in the morning, at noon and at night, respectively; and 100 bags are continuously taken for a course of treatment until symptoms completely disappear, irritant food such as seafood, beer and animal viscera is forbidden during taking ofthe tea bag, and people with serious symptoms can take the tea bag for 3-4 courses of treatment.

Wind-dispelling cold-eliminating walnut oil is prepared by adopting the following raw materials in parts by weight: 250 to 260 parts of wild walnut in east of China, 30 to 40 parts of flaxseed, 70 to 80 parts of rattan pepper, 50 to 60 parts of coconut shell, 70 to 80 parts of semen plantaginis, 70 to 80 parts of dianthus superbus, 70 to 80 parts of polygonum aviculare, 70 to 80 parts of talcum, 70 to 80 parts of jasmine, 70 to 80 parts of honey-fried licorice root, 70 to 80 parts of akebiaquinata and 70 to 80 parts of stewed rheum officinale and the like. By adding the rattan pepper, an effect for dispelling the wind and eliminating the wind can be realized; dianthus superbus and polygonum aviculare can clear away the internal heat and relieve stranguria by dieresis; akebiaquinata, talcum and semen plantaginis can clear away the internal heat, remove dampness and treat stranguria; jasmine and stewed rheum officinale can purge heat and reduce pathogenic fire; the honey-fried licorice root and regulation medicine can clear away the internal heat and dispelling the dampness. The wind-dispelling cold-eliminating walnut oil is suitable for people with dampness-heat in lower Jiao such as rheumatism, urocystitis, urethritis, urolithiasis, acute nephritis, acute prostatitis, nephropyelitis, acute renal failure, postpartum and postoperative urinary retention, chyluria and the like.

The invention discloses a bisulfonyl anthracenedione dioxime derivative serving as P2X<3> and P2X<2 / 3> receptor antagonists. The invention relates to a compound shown as a formula I and / or pharmaceutical salts thereof, a preparation method of the compound and / or pharmaceutical salts thereof, as well as a pharmaceutical composition containing the compound. The compound and the pharmaceutical salts thereof can be treating and / or preventing P2X<3> and P2X<2 / 3> receptor mediated diseases such as frequent micturition, urgent urination, uracratia, spontaneous bladder hypersensitivity, prostatitis, urocystitis, pain illnesses, and the like. The structural formula is as shown in the specification. If the substitution position of sulfonyl connected with R1 on an anthracene ring is defined as a position 2 of anthracene, a substitution position of sulfonyl connected with R2 on an anthracene ring is defined as a position 6 or 7, and 2,6- or 2,7-bis-substituted sulfonyl anthracene 9,10-diketone dioxime derivatives are formed. The R1 and R2 are independently selected from C1-C6 straight chain or branched alkyl, 3-8-membered alicyclic groups, aryl and heterocyclic aryl.