The invention discloses locust medicinal liquor, which is prepared from raw materials including rice wine of over 50 degrees, locust, crystal sugar, barbary wolfberry fruit, longan, ginseng table and the like. The locust medicinal liquor has a simple and reasonable formula, and is easy to prepare. Finished liquor is clear and yellow, smells good, tastes sweet, has the effects of relieving cough and asthma, expelling wind, removing dampness, relaxing and activating the tendons, and promoting blood circulation to remove blood stasis, is suitable for diseases such as infantile convulsion of infants suffering from tetanus, fever, asthma, an acute filthy disease, chilblain, tracheitis and the like, can be used for preventing cardiovascular and cerebrovascular diseases and the like, and has particularly remarkable effects on cough, insomnia, nocturia and neurasthenia.