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Chinese medicine oral preparation for treating gynecologic inflammation and its preparation method

A technology for oral preparations and gynecological inflammation, which is applied in the field of preparation of pharmaceuticals, can solve the problems of insufficient utilization of waste, inability to extract active ingredients, inability to fully exert therapeutic effects, etc., and achieve the effect of reducing production costs and reducing dosage

Inactive Publication Date: 2005-01-26
陈志成
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are certain defects in the above-mentioned preparation process, such as Cyperus Cyperi and Angelica Sinensis in the prescription without extracting the active ingredient volatile oil with pharmacological activity; Mixing and decocting one medicine for extraction cannot effectively extract the main active ingredients contained in each medicine, so the therapeutic effect of the formula cannot be fully utilized, and these medicines are not fully utilized, resulting in waste
On the other hand, from the perspective of dosage forms, there are no reports on the development of dosage forms of Fuyankang dropping pills and soft capsules.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 uses following raw material and method to prepare dropping pill

[0034] Raw material formula: 60g of red peony root, 100g of soil tuckahoe, 60g of Sanleng (stir-fried with vinegar), 60g of Toosendan (fried with vinegar), 60g of curcuma (fried with vinegar), 60g of Corydalis (fried with vinegar), 100g of Gorgon fruit (fried with vinegar), 100g of angelica, 60g of Sophora flavescens, 40g of Rhizoma Cyperi (burned with vinegar), 60g of Cortex Phellodendri, 100g of Salvia miltiorrhiza, and 120g of Chinese yam.

[0035] Preparation method: (1) Take Sophora flavescens, Corydalis Corydalis and Phellodendron Phellodendri, crush them into coarse powder, use 8 times the amount of 70% ethanol each time, reflux extract 3 times, 1 hour / time, combine the extracts, filter, and recover the filtrate under reduced pressure Concentrate ethanol to a relative density of 1.30-1.35 (60°C), vacuum-dry and pulverize to obtain alcohol-extracted dry cream powder such as Sophora flav...

Embodiment 2

[0043] Embodiment 2 prepares drop pill with following raw material and method

[0044] Raw material formula: 50g of red peony root, 110g of soil tuckahoe, 70g of Sanleng (stir-fried with vinegar), 70g of Toosendan (stir-fried), 70g of curcuma, 80g of Corydalis 80g, 80g of Gorgon, 100g of angelica, 80g of Sophora flavescens, 50g of Rhizoma Cyperi (stir-fried with vinegar) , Phellodendron 80g, Salvia miltiorrhiza 90g, Chinese yam 100g.

[0045] Preparation method: (1) Take Sophora flavescens, Corydalis Corydalis, Phellodendron Phellodendri, crush them into coarse powder, use 10 times the amount of 60% ethanol each time, reflux extract twice, 2 hours each time, combine the extracts, filter, and recover the filtrate under reduced pressure Concentrate ethanol to a relative density of 1.30-1.35 (60°C), vacuum-dry and pulverize to obtain alcohol-extracted dry cream powder such as Sophora flavescens;

[0046] (2) Take Rhizoma Cyperi and Angelica, crush them into coarse powder, add 12...

Embodiment 3

[0053] Embodiment 3 prepares soft capsule with following raw material and method

[0054] Raw material formula: with embodiment 1.

[0055] Preparation method: (1)~(5) are the same as embodiment 1;

[0056] (6) Take the volatile oils such as Rhizoma Rhizoma Cyperi and Zezhu volatile oil and mix them evenly, add 10 g of melted PVPk30 and 10 g of melted PEG8000, condense and solidify at low temperature, pulverize, and sieve to obtain powdered volatile oil;

[0057] (7) Take the above alcohol-extracted dry paste powder such as Sophora flavescens, water-extracted dry paste powder such as Rhizoma Cyperi, Radix Paeoniae Rubra and other water-extracted dry paste powder, Salvia miltiorrhiza extract powder, Curcuma extract powder, and powdered volatile oil, and mix evenly to obtain a mixture powder.

[0058] (8) Take the above-mentioned mixed medicinal powder, add it into 250g of soybean oil, stir evenly, then add 50g of soybean lecithin and 10g of Tween 85, stir evenly, then fully m...

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Abstract

The invention discloses a Chinese medicine oral preparation for treating gynecologic inflammation and its preparation method, wherein the preparation is prepared from 13 Chinese medicinal herb including radix paeoniae rubrathe, burred tuber, toosendan fruit, zedoary, corydalis tuber, gorgon euryale seed, Chinese angelica root, flavescent sophora root, cyperus tuber, Chinese yam,through sorted extraction, concentrating, drying to obtain extract powder, then charging auxiliary material to obtain drop pill or soft capsule.

Description

Technical field [0001] The invention belongs to the technical field of preparation of medicines, and in particular relates to a Chinese patent medicine oral preparation for treating gynecological inflammatory diseases and a preparation method thereof. Background technique [0002] Gynecological inflammatory diseases such as adnexitis, pelvic inflammatory disease, vaginitis, cystitis, urinary tract infection, etc. are common clinical diseases and frequently-occurring diseases. Stability and other factors, can not meet the clinical needs. The variety "Fuyankang Tablets" recorded in "Drug Standards of the Ministry of Health of the People's Republic of China" (ten volumes of traditional Chinese medicine preparations) is composed of red peony root, Smilax tuckahoe, Sanleng, Toosendan, Curcuma, Corydalis, Gorgon fruit, Angelica, Salvia miltiorrhiza Tablets made of thirteen traditional Chinese medicines such as flavescens, flavescens, cyperus, yam, etc., have the effects of promot...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/48A61P13/02A61P15/00A61P15/02
Inventor 陈志成
Owner 陈志成
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