Disclosed is a
prodrug of the formula: where A is a
sulfur or a
selenium, and R is derived from a mono- di- or oligo- saccharide.Also disclosed is a
prodrug of the formula: where A is
sulfur or
selenium, R′ is derived from a
sugar and R′ has the formula (CHOH)nCH2OH, where n is 1 to 5, or R′ is an
alkyl or
aryl group, orR′ is ═O, and the R″ groups may be the same or different and may be
hydrogen,
alkyl, alkoxy, carboxy.Also disclosed is a conjugate of an
antioxidant vitamin and a thiolamine or selenolamine.Also disclosed is a
prodrug of the formula; where A is
sulfur or
selenium, and R′ is derived from a
sugar and R′ has the formula (CHOH)nCH2OH, where n is 1 to 5, or R′ is also be an
alkyl or
aryl group, orR′ is ═O, and R‡ is an alkoxy, or an amine group.Also disclosed is a prodrug of the formula: where R is COOH or H, and R′ is derived from a
sugar and R′ has the formula (CHOH)nCH2OH,where n is 1 to 5, or R′ is an alkyl or
aryl group, or R′ is ═O.