2395 results about "Molecular geometry" patented technology

The present invention is directed to a process of atom (or group) transfer radical polymerization for the synthesis of novel homopolymer or a block or graft copolymer, optionally containing at least one polar group, with well defined molecular architecture and narrow polydipersity index, in the presence of an initiating system comprising (i) an initiator having a radically transferrable atom or group, (ii) a transition metal compound, and (iii) a ligand, the present invention is also directed to the synthesis of a macromolecule having at least two halogen groups which can be used as a macroinitiator component (i) to subsequently form a block or graft copolymer by an atom or group transfer radical polymerization process; the present invention is also directed to a process of atom or group transfer radical polymerization for the synthesis of a branched or hyperbranched polymer; in addition, the present invention is directed to a process of atom or group transfer radical polymerization for the synthesis of a macroinitiator which can subsequently be used to produce a block or graft copolymer.

Compositions containing one or more types of membrane-targeting antimicrobial agents immobilized on a substrate with activity in relevant biological environments, and methods of making and using thereof, are described herein. The antimicrobial agents retain their activity in the presence of blood proteins and / or in vivo due to improved molecular structures which allow for cooperative action of immobilized agents and hydrophilic chemistries which resist non-specific protein adsorption. Suitable molecular structures include branched structures, such as dendrimers and randomly branched polymers. The molecule structures may also include hydrophilic tethers which provide both flexibility and resistance to non-specific protein adsorption. The membrane targeting antimicrobial agent coatings can be applied to a variety of different types of substrates including medical implants such as vascular grafts, orthopedic devices, dialysis access grafts, and catheters; surgical tools, surgical garments; and bandages. The substrates can be composed of metallic materials, ceramics, polymers, fibers, inert materials such as silicon, and combinations thereof. The compositions described herein are substantially non-leaching, resistant to non-specific protein adsorption, and non-hemolytic.

Method and system for analyzing relationship between molecular structure and biological activity in one or more molecules by transforming molecular structure data into a hierarchical representation of chemical concepts and descriptors and detecting common tree-like patterns in the data.

A light-emitting element containing a light-emitting material and having high light emission efficiency is provided. The light-emitting element includes a host material and a guest material. The host material includes at least a first molecule and a second molecule having the same molecular structure. The guest material has a function of exhibiting fluorescence or converting triplet excitation energy into light emission. The first molecule and the second molecule each include a first skeleton, a second skeleton, and a third skeleton, and the first skeleton and the second skeleton are bonded to each other through the third skeleton. The first skeleton includes at least one of a π-electron rich heteroaromatic skeleton and an aromatic amine skeleton and the second skeleton includes a π-electron deficient heteroaromatic skeleton. The first molecule and the second molecule have a function of forming an excited complex.

A drug delivery balloon is provided, the a balloon having an outer surface, and a tunable coating disposed on at least a length of the balloon surface. The tunable coating includes a first therapeutic agent and a first excipient, and can include a second therapeutic agent and a second excipient. The first and second therapeutic agents have different dissolution rates during balloon inflation and therefore provide a coating that is tunable.

A method for manufacturing a lens of a polymer material, comprises producing in the core of the lens or on the surface of the latter at least one opaque zone having an optical function, by locally degrading the molecular structure of the polymer material using a beam of laser light. Example application is provided in particular but not exclusively to CMOS imagers.

Techniques for detecting fluorescence emitted by molecular constituents in a wall of a body lumen include introducing an autonomous solid support into the body lumen. Cells in a lumen wall of the body lumen are illuminated by a light source mounted to the solid support with a wavelength that excites a particular fluorescent signal. A detector mounted to the solid support detects whether illuminated cells emit the particular fluorescent signal. If the particular fluorescent signal is detected from the illuminated cells, then intensity or position in the lumen wall of the detected fluorescent signal, or both, is determined. These techniques allow the information collected by the capsule to support diagnosis and therapy of GI cancer and other intestinal pathologies and syndromes. For example, these techniques allow diagnostic imaging using endogenous and exogenous fluoroprobes, treating diseased sites by targeted release of drug with or without photoactivation, and determining therapeutic efficacy.

A polarization grating includes a substrate and a first polarization grating layer on the substrate. The first polarization grating layer includes a molecular structure that is twisted according to a first twist sense over a first thickness defined between opposing faces of the first polarization grating layer. Some embodiments may include a second polarization grating layer on the first polarization grating layer. The second polarization grating layer includes a molecular structure that is twisted according to a second twist sense that is opposite the first twist sense over a second thickness defined between opposing faces of the second polarization grating layer. Also, a switchable polarization grating includes a liquid crystal layer between first and second substrates. The liquid crystal layer includes liquid crystal molecules having respective relative orientations that are rotated over a thickness defined between opposing faces thereof by a twist angle that is different from a relative phase angle between respective first and second periodic alignment conditions of the first and second substrates. Related devices and fabrication methods are also discussed.

Apparatus and methods are provided that enable the interaction of low-energy electrons and positrons with sample ions to facilitate electron capture dissociation (ECD) and positron capture dissociation (PCD), respectively, within multipole ion guide structures. It has recently been discovered that fragmentation of protonated ions of many biomolecules via ECD often proceeds along fragmentation pathways not accessed by other dissociation methods, leading to molecular structure information not otherwise easily obtainable. However, such analyses have been limited to expensive Fourier transform ion cyclotron resonance (FTICR) mass spectrometers; the implementation of ECD within commonly-used multipole ion guide structures is problematic due to the disturbing effects of RF fields within such devices. The apparatus and methods described herein successfully overcome such difficulties, and allow ECD (and PCD) to be performed within multipole ion guides, either alone, or in combination with conventional ion fragmentation methods. Therefore, improved analytical performance and functionality of mass spectrometers that utilize multipole ion guides are provided.

The present invention provides a sugar-modified liposome having a sugar chain bonded to its membrane surface, preferably through a linker protein, and having excellent absorption qualities, particularly in the intestine. The molecular structure and quantity of the sugar chain is selectively varied to allow the liposome to be delivered in a targeted manner to selected cells and tissues. The liposome is applicable to medicinal drugs, cosmetics and other various products in the medical / pharmaceutical fields, and it is especially useful in a therapeutic drug delivery system that recognizes target cells and tissues, such as cancer cells, and in the delivery of drugs or genes locally to a selected region, or in a diagnostic cell / tissue sensing probe.

A device and method designed to carry out the computation of a wide range of topological indices of molecular structure to produce molecular descriptors, representing important elements of the molecular structure information including but not limited to molecular structure variables such as; the molecular connectivity chi indices, mXt, and mXtv; kappa shape indices, mκ and mκα; electrotopological state indices, Si; hydrogen electrotopological state indices, HESi; atom type and bond type electrotopological state indices; new group type and bond type electrotopological state indices; topological equivalence indices and total topological index; several information indices, including the Shannon and the Bonchen Trinajstic information indices; counts of graph paths, atoms, atoms types, bond types; and others.

A magnetic disk with which further reduction of magnetic spacing can be realized and which has high reliability under such circumstances of a lower floating amount of a magnetic head involved in the recent rapid increase in recording density and of extremely severe environmental resistance involved in diversification in use applications is provided.In a magnetic disk in which at least a magnetic layer, a protective layer, and the lubrication layer are sequentially provided on a substrate, the lubrication layer contains a lubricant compound for a magnetic disk, having a perfluoropolyether main chain in the molecular structure and a structure indicated as follows at a position close to the center of the molecule:-0-CH2—CH(OH)—CH2—CH2—CH(OH)—CH2-0-or-0-CH2—CH(OH)—CH(OH)—CH2-0-

The invention related to a polyimide film with high visible light permeability, molecular structure formula of which is: (shown in figure). Preparation comprises steps of: dissolving primary diamine in a strongly polarnon-proton solvent, cooling the same by cold water to 5 DEG. C to 10 DEG. C, adding aromatic dianhydride, mixing, reacting 4h to 10h at 5 DEG. C to 10 DEG. C, acquiring homogeneous, transparent, sticky polyamic acid resin solution; wherein mol number of aromatic dianhydride is equal to that of primary diamine; adjusting viscosity of polyamic acid resin solution by N,N-dimethyl acetamide, forming film in a casting machine, heating to raise temperature, processing dehydration heat imidization, cooling, deciduating to acquire homogeneous and transparent polyimide thin film. The preparation method has mild reaction condition, sample to operate, low in cost and environmental friendly; mechanical property and thermal stability of the polyimide thin film are excellent with high visible light permeability reaching 94% and film thickness 50 micrometers.

The invention provides a laser spectrum analyzer combining a confocal micro-Raman spectrometer with a laser-induced breakdown spectrometer (LIBS). The analyzer comprises a micro-Raman system, a micro LIBS system, a high resolution micro-imaging system, a confocal micro-light path, and a spectrum receiving system with a time resolution function, and automatically switches into a white light micro-imaging observation mode, an automatic focusing mode, a LIBS spectrum working mode, and a Raman spectrum working mode. The significant characteristics of the invention are that compact combination of Raman with LIBS is realized by a micro confocal system; qualitative and quantitative analysis of substance elements at the same minimal position and molecular structure is realized; with the high-resolution imaging function, element spatial discrimination and substance structure chemical analysis can be carried out in micrometers so as to obtain complete information of spatial distribution images of chemical elements, substance structure and physical conditions of a sample.

The invention relates to the technical field of organic luminescent materials, in particular to an organic electroluminescent material and a luminescent device with the same. The organic electroluminescent material comprises selected chemical compounds shown as a general formula I or a general formula II. The organic electroluminescent material and the luminescent device have the advantages that electron pushing and pulling common planes are formed by an electron donating Donor and an electron sucking Acceptor, and accordingly rigid molecular structures can be obtained; HOMO-LUMO (highest occupied molecular orbits-lowest unoccupied molecular orbits) are separated from one another to a certain extent, and accordingly the organic electroluminescent material and the luminescent device are narrow in FWHM (full width at half maximum) and have high transition rate constants Kr.

The invention discloses a colorless and transparent aromatic polyimide film which has the general formula of molecular structure as follows; the preparation thereof includes: aromatic primary amine and aromatic acid anhydride with specific molecular structures are adopted for polymerization in a strong polar aprotic organic solvent system within the temperature range of 0 DEG C to 35 DEG C to prepare a colorless and transparent viscous polyamide acid solution with homogeneous phase. Viscosity adjustment, casting for forming the film, heating for rising temperature and solvent removal are carried out simultaneously when partial imidization reaction is carried out, and then demoulding and stretching, further deep thermal imidization and rolling are carried out to obtain the colorless and transparent aromatic polyimide film. No special production equipment is required by the invention so that production can be carried out on the conventional production line of the polyimide film and the polyimide film is applicable to industrialized production.

A lithium secondary battery includes: an electrode body having a positive electrode, a negative electrode, and a separator, the positive electrode and the negative electrode being wound or laminated by means of the separator; and a nonaqueous electrolyte solution containing a lithium compound as a electrolyte. At least one of the positive electrode, the negative electrode, the separator, the nonaqueous electrolyte solution contains at least one of: (a) an organic and / or inorganic inhibitor, which functions as a Cu-corrosion inhibitor or a Cu-trapping agent, (b) a compound having an organic base and an inorganic acid which are unitarily combined in a molecule, (c) a cyclic compound containing a N-O radical in a molecular structure, (d) a cyclic compound which becomes a Mn<2+> supplier in the nonaqueous electrolyte solution, (e) a compound containing an atom showing Lewis acidity and an atom showing Lewis basisity in one molecule, (f) a three-dimensional siloxane compound, and (g) a nonionic surfactant; or the nonaqueous electrolyte solution contains: (h) a water-extracting agent, or (i) a hydrofluoric acid-extracting agent. This lithium secondary battery exhibits an excellent effect that self-discharge property, cycle characteristics, long period stability and reliability can be planned.

The present invention relates to the technical field of organic light-emitting materials, and in particular relates to an organic electroluminescent material and a light-emitting device thereof. The organic electroluminescent material is selected from the compounds as shown in Formula I. A rigid molecular structure is obtained by forming of a push-pull electron coplane of electron donating Donor and electron-withdrawing acceptor, certain separation of HOMO-LUMO is obtained so as to obtain narrow FWHM and high transition rate constant Kr.

The invention relates to a preparation method of a star polycarboxylic acid high-performance water reducing agent. Polybasic alcohol and (methyl) acrylic acid used as main raw materials for esterification are esterified and polymerized to prepare the star polycarboxylic acid high-performance water reducing agent material: the (methyl) acrylic acid and polybasic alcohol used as reactants are esterified under the action of a catalyst to firstly prepare a star polymerizable active terminal, and free-radical polymerization reaction is carried out with unsaturated polyethenoxy ether, molecular weight regulator and unsaturated carboxylic acid monomer under the action of an initiator to prepare the star polycarboxylic acid high-performance water reducing agent. The invention is easy to control, and has the advantages of high polymerization degree, low cost and no pollution; the esterification reaction is carried out form an active core, and the free-radical polymerization is carried out to generate the chain arm, thereby implementing the polycarboxylic acid high-performance water reducing agent in a star molecular structure; and under the condition of common doping amount and low doping amount, the star polycarboxylic acid high-performance water reducing agent has better cement paste flowability and holding capacity than the traditional linear and comb polycarboxylic acid water reducing agents, and has favorable cement adaptability and concrete application performance.

The invention provides a preparation method of a matting leather water-based polyurethane coating agent. According to the preparation method, a polyurethane A component with a cross-linked structure and a large particle size is synthesized, and is mixed with a B component with a small particle size. The A component possesses many molecular branched chains, size of micellar particles is relatively large, and specific gravity of the A component is less than that of the component B; so that the A component will float on film surface, roughness of the film surface is relatively high, delustering effect is achieved, no delustering agent is needed, excellent transparency is obtained after coating, and no influence on leather substances is caused as the delustering effect is achieved.

A magnetic carrier composed of carrier particles is provided in which each carrier particle has a carrier core including magnetic fine particles and a binder resin with the carrier core surface being coated with a coat material containing a coat resin. In the magnetic carrier, Fatom / Catom and (Fatom / Catom) / (Fcalc / Ccalc) are respectively in specific ranges, wherein Fatom and Catom represent respectively a fluorine element abundance ratio and a carbon element abundance ratio at the magnetic carrier particle surface, and Fcalc and Ccalc represent respectively a fluorine element abundance ratio and a carbon element abundance ratio which are calculable from the molecular structure of the coat resin.In addition, a two-component developer is provoded including the magnetic carrier and a toner having a specific contact angle against water.

The invention discloses an alkali-free chlorine-free high-early-strength liquid accelerator and a preparation method thereof, and belongs to the technical field of building materials. The alkali-free chlorine-free high-early-strength liquid accelerator is synthesized by aluminum sulfate (a), alkaline earth metal salt (b), aluminum hydroxide (c), hydroxy carboxylic acid (d), an organic amine compound (e) and a stabilizing agent (f). The invention is characterized in that: the organic amine compound, a polyhydroxy organic matter and inorganic salt are subjected to complex reaction, and the molecular structure of the product is regulated by regulating a ratio of (a) to (b) to (c) to (d) to (e) to (f) so as to improve the performance of the product. Mortar doped with the product has the advantages of adjustable setting time, one-day compressive strength of over 20MPa and a 28-day compressive strength ratio of about 100 percent, the synthesis process is simple, reaction conditions are mild, and the alkali-free liquid accelerator has good performance.

A diffuser provides the ability to diffuse one or more infusion materials into a host material. A rotor and stator rotate relative to one another. The infusion materials are drawn through openings in the rotor and stator. These openings are also causing turbulence within the host material, which is flowing through an area between the rotor and stator. As aligned openings pass one another, succussion occurs, which provides energy to diffuse the infusion materials into the host material to an extremely high degree. The opening patterns in the rotor and stator can be designed to operate at a single frequency or at multiple frequencies. The frequencies of operation may affect bonding between the infusion materials and the host material and may also be effective in break down of complex molecular structures.

A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.

A diffuser provides the ability to diffuse one or more infusion materials into a host material. A rotor and stator rotate relative to one another. The infusion materials are drawn through openings in the rotor and stator. These openings are also causing turbulence within the host material, which is flowing through an area between the rotor and stator. As aligned openings pass one another, succussion occurs, which provides energy to diffuse the infusion materials into the host material to an extremely high degree. The opening patterns in the rotor and stator can be designed to operate at a single frequency or at multiple frequencies. The frequencies of operation may affect bonding between the infusion materials and the host material and may also be effective in break down of complex molecular structures.

A method of producing carbon macro-molecular structures includes dissolving a graphitic material in a solvent to provide a suspension of carbon-based macro-molecular structures in the solvent, and obtaining a plurality of the carbon macro-molecular structures from the suspension. The plurality of carbon macro-molecular structures obtained from the suspension each consists essentially of carbon. A material according to some embodiments of the current invention is produced according to the method of producing carbon macro-molecular structures. An electrical, electronic or electro-optic device includes material produced according to the methods of the current invention. A composite material according to some embodiments of the current invention has carbon macro-molecular structures produced according to methods of producing carbon macro-molecular structures according to some embodiments of the current invention. A hydrogen storage device according to some embodiments of the current invention has carbon macro-molecular structures produced according to methods of producing carbon macro-molecular structures according to some embodiments of the current invention. An electrode according to some embodiments of the current invention has carbon macro-molecular structures produced according to methods of producing carbon macro-molecular structures according to some embodiments of the current invention.

Acid-containing oral pharmaceutical compositions are provided wherein the pharmaceutical active agents are peptide compounds (i.e., those that include a plurality of amino acids and at least one peptide bond in their molecular structures). Certain barrier layers and / or particulate coated acid are used to reduce any adverse interactions that might otherwise occur between the acid of the compositions and other components of the composition. Use of these barrier layers and / or use of particulate coated acid is believed to promote a more simultaneous release of the components of the composition than is achieved by prior art acid-protection techniques, thus enhancing, and making more consistent, the bioavailability of the active peptide compounds.