The invention provides an antineoplastic traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicine. The antineoplastic traditional Chinese medicine composition comprises an A component and a B component; the A component comprises red date, Chinese yam, semen coicis, rhizoma atractylodis macrocephalae, radix codonopsis, radix salviae miltiorrhizae,licorice root, rhizoma polygonati, radix notoginseng, fructus hordei germinatus, bulbus lilii, black rice, black soybean hull, black fungus, lotus seed, tremella fuciformis, sugar candy and garlic juice; the B component comprises ground beeltle, caulis spatholobi, spreading hedyotis herb, herba taraxaci, rhizoma curcumae, common selfheal fruit-spike, rhizoma paridis, angelica sinensis, ginseng, radix astragali, Chinese caterpillar fungus, lucid ganoderma, radix sophorae flavescentis, rhizome chuanxiong, pericarpium citri reticulatae, licorice root, calculus bovis, cortex phellodendri and honey. The provided antineoplastic traditional Chinese medicine composition can effectively resist melanoma, prostatic cancer, lung cancer, colon cancer, liver cancer, pancreatic cancer, esophagus cancer,gastric adenocarcinoma, lymphoma, breast cancer and cervical cancer.