55 results about "Folsomia candida" patented technology

The invention encompasses hexapeptides consisting of alternating hydrophobic residues (B) at positions 2, 4, and 6, hydrophilic, charged residues (X) at positions 1 and 3, and a naphthylalanine (Nal), an aliphatic or aromatic residue (O) at position five, represented generally by the formula XBXBOB, which exhibit antimicrobial activity against infections caused by a variety of pathogens. These pathogens may include gram positive or negative bacteria, acid-fast bacteria such as mycobacteria, parasites, dermatophytes, or fungal pathogens. Typical fungal pathogens include Candida albicans and typical dermatophytes include Trichophyton rubrum and Trichophyton mentagrophytes. The hexapeptides of the present invention exhibit antifungal activity, antibacterial activity, desirable stability, and lack toxicity to the mammal receiving treatment.

The invention provides a vaccine including an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, with an adjuvant in a pharmaceutically acceptable medium. The invention also provides a method of treating or preventing hematogenously disseminated or mucocutaneous candidiasis. The method includes administering an immunogenic amount of a vaccine an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, in a pharmaceutically acceptable medium.

The present invention provides novel compounds (e.g., compounds of Formula (I)), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits comprising the inventive compounds, or compositions thereof, for treating and / or preventing a fungal or protozoan infection, inhibiting the activity of a fungal or protozoan enzyme, killing a fungus or protozoon, or inhibiting the growth of a fungus or protozoon. The fungus may be a Candida species, Aspergillus species, or other pathogenic fungal species. The compounds of the invention may inhibit the activity of fungal or protozoan cytochrome b and / or fungal or protozoan Hsp90. The present invention also provides synthetic methods of the inventive compounds.

The invention provides a test method for detecting the potential toxic influence of stomach poisoning insecticide compounds on folsomia candida. The method is characterized in that an insecticide or transgenic insecticidal protein is added into yeast powder (feed) uniformly and the mixture is directly delivered to folsomia candida; yeast mixed with a protease inhibitor with a concentration of 75 micrograms E-64 / g is used for positive control treatment and feed without any insecticide compounds is used for negative control treatment; potential toxicity of the tested insecticide compounds on spring tails is assessed by comparing the important life parameters such as the survival rate, the head breadth, the body length and the egg laying amount of folsomia candida of the treatment group and the control groups. By using the method, the biological reaction of folsomia candida to potassium arsenate [PA], E-64 and galanthus nivalis agglutinin (GNA) with different concentrations can be tested. It is shown that the different life parameters of folsomia candida show an obvious dose-effect relationship along with the change of the concentrations of PA, E-64 and GNA, so that the effectiveness and the sensitivity of the method are testified.

The invention relates to primers and TaqMan probes used for carrying out two-channel fluorescence PCR detection of trichomonas vaginalis viruses and candida albicans viruses. The primers and the TaqMan probes are trichomonas vaginalis virus primers and trichomonas vaginalis virus TaqMan probes designed based on a trichomonas vaginalis virus conserved area and candida albicans virus primers and candida albicans virus TaqMan probes designed based on a candida albicans virus conserved area. Simultaneously, the primers and the TaqMan probes are used for detecting whether trichomonas vaginalis virus RNA and candida albicans virus DNA exist in a sample to be detected. The invention further comprises a detection method employing the primers and the TaqMan probes and a kit containing the primers and the TaqMan probes.

Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g / l of xylose, 1 10 g / l of urea, 1 10 g / l of potassium diphosphate, 0.01 1 g / l of magnesium sulfate, 0.1-10 mg / l of MnSO4.4H2O, 0.1 10 mg / l of CoCl2.6H2O, 0.1 10 mg / l of NaMoO4.2H2O, 0.1 10 mg / l of ZnSO4.7H2O, 0.1 10 mg / l of AlCl3.6H2O, 0.1 10 mg / l of CuCl2.2H2O, 0.01-5 mg / l of H3BO3, 1-100 mg / l of FeSO4 7H2O, 0.1-10 mg / l of ascorbic acid, 1-100 mg / l of biotin, 1-100 mg of choline, 1-200 mg / l of folic acid, 1-100 mg / l of inositol, 1-100 mg / l of nicotinic acid, 0.1-10 mg / l of p-aminobezoic acid, 1-100 mg / l of pantothenic acid, 0.1-10 mg / l of pyridoxine, 10-1,000 mg / l of riboflavin, and 1-100 mg / l of thiamine.

The invention belongs to the bio-technical field, and particularly discloses a quick preparation method for a candida albicans specimen for field emission scanning electron microscope. The quick preparation method is characterized in that candida albicans thalluses are added into a glutaraldehyde fixing solution for being fixed; sterile deionized water is adopted to clean; and tertiary butanol with different concentration gradients is adopted for dehydration; a bacteria solution is dropped into pure tertiary butanol to freeze in a refrigerator of 4 DEG C; and after a dried specimen is sprayed with gold in an ion sputtering mode, the morphological structure of a thallus biological membrane can be observed through a scanning electron microscope by regulating and setting parameters. According to the quick preparation method for the candida albicans specimen for field emission scanning electron microscope provided by the invention, excreta of the candida albicans is reduced to affect image-forming quality of the specimen; a phenomenon that some samples are covered and shielded by phosphate particles is eliminated to the greatest extent; tiny deformation of the specimen is reduced and the biological membrane is prevented from dropping slightly; the surface of the thallus biological membrane is prevented from cracks or shrinkage sinking of varying degrees and even breakage; and meanwhile, damages on the surfaces of the thualuses are eliminated.