Traditional Chinese medicine composition for preparing Candida resisting medicines

Abstract

The invention relates to a traditional Chinese medicine composition for preparing Candida resisting medicines. The traditional Chinese medicine composition contains the ingredients in parts by weight: 40-80 parts of cinnamaldehyde and 30-60 parts of pogostone. The traditional Chinese medicine composition for preparing the Candida resisting medicines, provided by the invention, can be used for treating deep or systemic fungal infections caused by Candida, including deep or systemic fungal infections caused by Candida albicans, Candida tropicalis, Candida krusei or Candida glabrata. According to the traditional Chinese medicine composition, the pogostone is screened from numerous ingredients of ageratum oil, has relatively high bacteriostasis activity and has a good synergistic effect with the cinnamaldehyde; the cinnamaldehyde and the pogostone are suitable for being used after being combined; compared with the bacteriostasis activity after the cinnamaldehyde and the ageratum oil are combined, the bacteriostasis activity after the pogostone and the cinnamaldehyde are combined is remarkably improved, and the safety is good.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, which can be used for preparing medicines against candida infection. Background technique [0002] With the wide application of broad-spectrum antibiotics, corticosteroids and immunosuppressants, deep fungal infections have become more and more common in various clinical disciplines, and have become a serious complication of high-risk patients. , AIDS and other important factors of death. The first pathogenic bacterium is Candida, with a fatality rate of 30-60%, among which the mortality rate of Candida krusei infection is as high as 100%. At present, the treatment of deep fungal infection caused by Candida is multi-system chemical synthesis, such as fluconazole, itraconazole, caspofungin, voriconazole, etc. Although they have different degrees of antibacterial effects, they are all expensive and have serious side effects. specialty. Therefore, in order to discover high-efficiency ...

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Problems solved by technology

And in many patents of traditional Chinese medicine preparations, Tween 80 is also widely used, such as the use of Tween 80 as an emulsifier in the patent CN101982109A, and the use of Tween 80 as a surfactant in the patents CN102283806A and CN102526010A, but in the above patents, Tween 80 The usage is relatively large, more than 10%

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