55 results about "Eyes inflammation" patented technology

Provided herein are methods of evaluating efficacy of a treatment in a subject having eye inflammation (e.g., a subject having dry eye syndrome) and selecting a subject for participation in a clinical study. Also provided are methods of treating a subject having eye inflammation (e.g., a subject having dry eye syndrome).

The invention provides a steam heat eye mask which solves the problem that eyeballs are prone to being damaged due to excess local temperature of a conventional steam eye mask. The steam heat eye mask comprises an eye mask body and hangers. The eye mask body comprises a first airway surface and a second airway surface which are adhered to form a first cavity, heating units are arranged in the first cavity, and none-heat areas are arranged in the middles of the heating units. The hangers are arranged on both the left side and the right side of the eye mask body. The steam heat eye mask can emit persistent heat for about 15-30 minutes at the heating temperature of 40-45 DEG C, is simple to operate, and safe to use; symptoms such as eye drying, eyes being unsmooth, eyestrain and eye inflammation are significantly improved, so that the steam heat eye mask is adaptable to commercial application.

An ophthalmic solution comprising: a) a human recombinant lysozyme; b) one or more natural lacrophyl substances; c) water; and d) optionally one or more therapeutic substances. The ophthalmic solution is useful to treat dry eye conditions and eye inflammation and also to condition and / or cleanse contact lenses. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims.

The invention relates to biomaterial hydrogel eye drops containing stem cell secreted exosome, good in cellular biocompatibility and biological activity. Active hydrogel can serve as the eye drops, and the exosome is slowly released into damaged tissue; the hydrogel can also enhance retention and local concentration of the exosome at injured sites to promote repair of eye tissue injuries, promotecorneal cells to survive and proliferate, reduce apoptosis, promote functional recovery of the injured sites, inhibit pathological angiogenesis and inhibit eye inflammation; meanwhile, after the active hydrogel is combined with the bioactive material, residence time of the exosome can be prolonged, drug treating times can be reduced, and accurate control of drug dosage is facilitated.

The invention discloses an external spraying agent and / or eye drop of compound oil nano-emulsion as well as preparation method thereof. The pH value of the spraying agent and / or eye drop is 3-9. The spraying agent and / or eye drop comprise the following components according to the weight portion: 5-15 of compound oil, 0.5-2.0 of phospholipid, 0.5-3.0 of propanetriol, sodium hydroxide and medicinal water, wherein the compound oil comprises the following components: (1) zedoary turmeric oil and / or peppermint oil, and (2) soybean oil and / or castor oil. The mass ratio of the (1) and the (2) in the compound oil is 1:99-30:70. The spraying agent of the compound oil nano-emulsion, which is prepared by the invention, is used for antibiosis, inflammation diminishing and wound healing in the process of curing burn and scald. The eye drop of the compound oil nano-emulsion is used for curing eye strain, xerophthalmia and eye inflammation.

The invention discloses a Chinese herba preparation for treating eye inflammation and a preparation method of the traditional Chinese preparation. The Chinese herba preparation is prepared by cassia occidentalis, concha haliotidis, bat dung, centipeda minima, emilia sonchifolia, pipewort, feather cockscomb seeds, wild chrysanthemum flower, rehmannia glutinosa, Chinese yam, pulp of dogwood fruit, rhizoma alismatis, tuckahoe, cortex moutan radicis, wolfberry, cape jasmine, mother of pearl, scouring rush, bamboo shavings, caltrop and roots of hairy asiabell. The Chinese herba preparation is a Chinese medicinal herb preparation, and has a good treatment effect for acute or chronic conjunctivitis, central retinitis and optic neuritis, and after the Chinese herba preparation is clinically used for treating more than totally 100 cases of eye diseases of more than 600 patients for more than ten years, effective rate can be higher than 90%. In addition, according to clinical verifications, the Chinese herba preparation does not cause drug resistance and does not have toxic and side effects.

The invention discloses eye disease ointment for pets. The eye disease ointment comprises the following components in percentage by mass: 0.1%-3% of a chrysanthemum flower extract, 0.5%-4% of a honeysuckle flower extract, 0.1%-2% of a white mulberry root bark extract, 0.1%-3% of a radix angelicae sinensis extract, 0.1%-3% of a licorice root extract, 0.5%-3% of a radix astragali extract, 0.1%-3% ofa rhizoma anemarrhenae extract, 0.1%-3% of a dandelion extract, 0.1-3% of a rhizoma cimicifugae extract, 3%-12% of white sugar, 1%-10% of milk powder, 8%-16% of cattle hydolysis cream, 8%-20% of animal oil, 3-13% of chicken liver powder, 0.5%-3% of sodium carboxymethyl cellulose, 0.1%-0.35% of sodium benzoate, 0.00025% of vitamin A, 0.005% of vitamin B1, 0.005% of vitamin B2, 0.0025% of vitamin B6, 0.00005% of vitamin B12, 0.05% of vitamin E, 0.5% of taurine and the balance of water. Therefore, the eye disease ointment for pets, disclosed by the invention, has the effects of assisting in eliminating eye inflammation of pet cats, and accelerating the tissue repair function of cornea and conjunctiva.

The invention provides a pharmaceutical composition, in particular relating to a pharmaceutical composition for the treatment of eye diseases, especially eye inflammation. The pharmaceutical composition for the treatment of eye diseases consists of active ingredients and one or a plurality of accessories that are pharmaceutically acceptable, and is characterized in that the active ingredients of the pharmaceutical composition are one or a plurality of prostaglandin analogs and one or a plurality of glucocorticoids.

Inflammation and vascular abnormalities of the eye, including those related to ischemia, its prophylaxis and its alleviation, are treated by administration to the mammal of small amounts of phosphate-glycerol group presenting bodies such as phosphatidylglycerol liposomes.

The application discloses a visual fatigue reminding method. The method comprises the following steps that: when a user is detected to be in an eye use state, environmental information and eye use data are obtained; the environment information and the eye use data are scored according to a preset scoring standard to obtain a visual fatigue value; whether the visual fatigue value exceeds a first threshold value or not is determined; and if so, first reminding information is sent out. According to the application, the environmental information and the eye use data are scored according to the preset scoring standard to obtain the visual fatigue value; finally, whether the visual fatigue value exceeds the first threshold value or not is determined; and if so, first reminding information is sent out, so that the user can receive the first reminding information in time when being in the visual fatigue state and thus corresponding measures are taken to relieve the visual fatigue. Therefore, the probability of eye inflammation caused by eye fatigue is reduced; and the eyesight of the user can be protected. The invention further provides a visual fatigue reminding device and equipment and areadable storage medium that have the above beneficial effects.

The invention discloses eye drops containing fullerene and fullerene derivatives and a preparation method of the eye drops, and belongs to the technical field of eye drops. The eye drops comprise at least one of fullerene and fullerene derivatives, and the mass concentration of the fullerene and fullerene derivatives is 0.01%-10%. The eye drops further comprise taurine, sodium hyaluronate and water for injection, wherein the mass concentration of taurine is 0.1%-10%, the mass concentration of sodium hyaluronate is 0.01%-0.5%, and the mass concentration of water for injection is 90-99%. The fullerene and fullerene derivatives can be used for cell protection, sterilization and virus resistance, the taurine can be used for inhibiting eye inflammation, and the sodium hyaluronate can be used for relieving eye fatigue, so that the eye drops disclosed by the invention can be used for safely and efficiently treating eye inflammation diseases.

The invention discloses an application of anthracene nucleus antibiotic and its pharmaceutical salt for treating ocular inflammation. The invention found that the anthracene nucleus antibiotic and its pharmaceutical salt have good effect on treatment of exogenous ocular inflammation and endogenous ocular inflammation, and especially the anthracene nucleus antibiotics can be prepared to prolonged action preparations such as a nano preparation, a microballoon preparation, liposome and hydrogel, the curative effect can be directly performed on ocular surface and eye ground, the toxicity of anthracene nucleus antibiotic is reduced, administration dosage is simultaneously enlarged through ophthalmic administration by prolonged action preparations, the duration time of drug effect is long, the medicament curative effect is stronger than that of the common preparations of the anthracene nucleus antibiotic, when the ophthalmic administration is carried out, the anthracene nucleus antibiotic has good treatment effect for exogenous and endogenous ocular surface, and eye ground inflammation, and especially has good treatment effect for the ocular surface and eye ground diseases caused by external wound, so that the problems of certain eyes inflammation with long treatment and more severe eye diseases due to eyes inflammation can be solved.

Provided herein are methods of evaluating efficacy of a treatment in a subject having eye inflammation (e.g., a subject having dry eye syndrome) and selecting a subject for participation in a clinical study. Also provided are methods of treating a subject having eye inflammation (e.g., a subject having dry eye syndrome).

A surgical apron sheet to cover the face to prevent eye inflammation and the like caused by, inter alia, scattering oral bacteria, while also facilitating treatment of the oral cavity. The surgical apron sheet has a structure that resists slipping when covering the face during treatment of the oral cavity and is easy to manufacture at low cost. The surgical apron sheet of apron shape includes a face covering portion to cover the face of a patient during treatment and provided with a mouth-like opening. The opening is provided at a lower end with an engaging portion cut as a long hole of substantially semi-elliptic shape to engage a submental region or lower jaw line of the patient being treated.

The invention provides eye cream containing an anti-aging composition and a preparation method of the eye cream. The eye cream containing the anti-aging composition is prepared from the following raw materials: the anti-aging composition, a skin conditioner, an emulsifier, a humectant and water; the anti-aging composition comprises a hedychium coronarium root extract, a radix scutellariae root extract and a cocoa seed extract; the skin conditioner is prepared from herba siegesbeckiae extract, albizia bark extract, dipeptide-2, palmitoyl tetrapeptide-7, hesperidin methyl chalcone, PCA sodium, erythritol, hydrolyzed collagen, chondrus crispus extract and hexapeptide-9. The eye cream disclosed by the invention can penetrate into skin to improve eye microcirculation, reduce eye inflammation and fade eye pigmentation, so that dark circles are improved, and eye peripheries are brightened; and the eye wrinkle can be obviously faded, the eye skin can be tightened, the endogenous aging can be resisted, and the elasticity of the eye skin can be recovered.

The invention discloses nourishing and eye brightening eye cold compress gel. The eye cold compress gel is prepared from, by weight, 30-50 parts of a musaceae plant extracting solution, 30-50 parts of a blueberry extracting solution, 15-30 parts of a semen cassiae extracting solution and 15-30 parts of a hydrolyzed pearl solution. The eye cold compress gel has the advantages that the compatibility is reasonable, and through fermentation and distillation, the molecular weight of active ingredients in traditional Chinese medicine is reduced, the gel is more easily absorbed by the body and the quickly exerts the effect, and the utilization rate of the effective ingredients of the traditional Chinese medicine is increased; the prepared nourishing and eye brightening eye cold compress gel can effectively cure excess heat syndromes, deficiency fire syndromes and keratitis, conjunctivitis, cataract, glaucoma, ocular hypertension, caligo, giddiness, eye itching, dry eyes, tear gland retardance, eyestrain, trachoma, eye inflammation, tearing against wind, vision diminution and blurring, eye microcirculation disturbance and other symptoms which are caused by hyperactivity of liver-yang, liver wind dyskinesias, deficiency fire uptrend and the like.

The invention provides herba corydalis saxicolae tea. The herba corydalis saxicolae tea is prepared from, by weight, 20-40 parts of herba corydalis saxicolae, 20-40 parts of sweet tea, 20-40 parts of fructus momordicae and 20-40 parts of licorice roots, wherein the weight parts are metered by the dry raw materials with the water content not exceeding 10%. The herba corydalis saxicolae tea has the effects of clearing away heat and toxic materials, promoting diuresis, moistening the lung to benefit the throat and expelling phlegm to arrest coughing, can treat hepatitis, aphthous stomatitis, sphagitis, amygdalitis, an eye inflammation, slight corneal opacity, dysentery, diarrhea, abdominal pain, acute gastritis, constipation, hemorrhoidal bleeding and the like and also has the nutrition and healthcare effects; in addition, due to the fact that the herba corydalis saxicolae tea belongs to a sugar-free product, the herba corydalis saxicolae tea is specially suitable for obese people and diabetic patients and can reduce weight and fat, and patients suffering from cardiovascular diseases, obesity, diabetes and the like all can drink the tea; the herba corydalis saxicolae tea is good in mouthfeel and convenient to take and can be drunk by being directly brewed with boiling water. The invention further provides a preparation method of the herba corydalis saxicolae tea.

The invention relates to an ophthalmic lens, which comprises a matrix and a Euphrasia pectinata extract dispersed in the matrix. The ophthalmic lens contains the Euphrasia pectinata extract, which can be slowly released from the ophthalmic lens to treat eye inflammation (like conjunctivitis, blepharitis, hordeola), eye bleeding, eyestrain and other symptoms. The released Euphrasia pectinata extract also has the effects of disinfection, antioxidation, eyesight improving, eye function improving, pouch eliminating, and black eye elimination, etc. In addition, the invention also provides a preparation method of the ophthalmic lens.

The invention discloses an application of a polypeptide in a medicine for treating eye inflammation. The amino acid sequence of the polypeptide is YGRKKRRQRRRMMPYSTELIFYIEMDP. Eye drops prepared fromthe polypeptide comprise the following components in percentage by weight: 0.05-1% of polypeptide, and the eye inflammation is conjunctivitis, keratitis and / or uveitis. In the polypeptide eye drops, the pharmacological action of the polypeptide in treatment of inflammation is to inhibit inflammation from participating in cell proliferation, inhibit NF-kB activation, inhibit the generation and secretion of various inflammatory mediators, inhibit the growth of new capillaries, inhibit the aggregation and infiltration of inflammatory cells and the like. The polypeptide eye drops are clear in pharmacology, good in curative effect, low in side effect, stable in biological activity of bulk drugs, simple in production process, low in cost and beneficial to large-scale clinical application and reduction of burden of patients.

Disclosed is a process for preparing capsules and pills for treating eye inflammation caused by electro-optical, wherein the which is prepared from glucose as the host, as well as goldthread root, mulberry leaf and honeysuckle flower. The medicament can be used for treating a plurality of eye diseases, or for protecting eyes, improving eyesight and eye fatigue. The invention realizes simple formulation, low cost of preparation. easy production, easiness in use, and precise curative effect.

The invention discloses a health care eyepatch and a preparation method thereof. The health care eyepatch is prepared from a bag-shaped eyepatch body and a medicine bag filled in the eyepatch body, wherein the medicine bag is prepared from the following raw materials in parts by weight: 1 to 5 parts of buckwheat flavonoids, 1 to 10 parts of chrysanthemum flowers, 1 to 10 parts of semen cassiae, 1to 10 parts of rhizoma chuanxiong, 1 to 10 parts of herba menthae, 1 to 10 parts of radix angelicae, 1 to 10 parts of cacumen platyclade and 0.01 to 1 part of borneol. According to the conventional Chinese medicine theory, the reasonable recipe is used; the method of treating an internal illness by external treatment is used; by a body entering mode of the medicine through action on the specific acupuncture points, local percutaneous absorption, skin and respiration matters, the effects of relieving asthenopia and preventing myopia, glaucoma, cataract and various eye inflammations are achieved; the health care effect is durable and constant.

The invention discloses a meadowrue corydalis root beverage. The meadowrue corydalis root beverage is prepared from, by weight, 50-80 parts of a component A, 0-20 parts of saccharose and 30-50 parts of cyclodextrin. The component A is water extract of a mixture of 20-40 parts of meadowrue corydalis roots, 10-30 parts of sweet tea, 20-50 parts of grosvener siraitia and 20-40 parts of licorice roots, wherein the grosvener siraitia in the mixture is a baked product, and other raw materials are dried until the water content is 10%. The meadowrue corydalis root beverage is good in taste, has the effects of clearing away heat and toxic materials, removing dampness by dieresis, moistening the lung, relieving sore throat and expelling phlegm to arrest coughing, can treat hepatitis, erosion of mucous membrane in the oral cavity, sphagitis, amygdalitis, an eye inflammation, corneal opacity, dysentery, diarrhea, stomachache, acute gastritis, constipation, hemorrhoidal bleeding and the like and has an nutrition and healthcare effect. The product without saccharose is particularly suitable for obese groups and diabetics, can lose weight and reduce lipid and can be drunk by patients with cardiovascular diseases, the obese groups and the diabetics. The invention further provides a preparation method of the meadowrue corydalis root beverage.

The invention relates to an inflammation relieving and eyesight improving eye drop, which is prepared by blending chrysanthemum, Radix Rehmanniae Preparata, Fructus Lycii, Concha Haliotidis, borneol, vitamin B6, a Thamnolia vermicularis extract, Semen Celosiae, and borax according to certain proportion. Belonging to externally used eye care products, the inflammation relieving and eyesight improving eye drop provided in the invention has the efficacy of wind dissipating and heat clearing, liver calming and yang suppressing, nebula removing for eyesight improving and the like, and especially plays a health care role in promoting recovery of eye dryness, eyestrain, eye itching and other eye discomfort caused by eye inflammation, blurred vision and asthenopia, etc. Thus, the eye drop is widely applicable to asthenopia, dim sight, blurred vision, conjunctival congestion, eye dryness, strain, itching, pain, acidity and swelling, juvenile pseudomyopia and amblyopia, people operating computers, reading books and watching TV for a long time, and people wearing contact lenses, etc.

The invention relates to a traditional Chinese medicine composition for treating conjunctivitis. The traditional Chinese medicine composition comprises, by weight, 8-12 parts of poria cocos peel, 9-15 parts of oriental wormwood, 9-15 parts of radix stephaniae tetrandrae, 25-35 parts of coix seed, 8-12 parts of radix sileris, 8-12 parts of radix angelicae dahuricae, 5-7 parts of fructus kochiae, 9-15 parts of honeysuckle, 9-15 parts of fructus forsythia, 25-35 parts of houttuynia cordata, 5-7 parts of scorch-fried cape jasmine, 13-17 parts of garter snake and 17-23 parts of geranium wilfordii. The traditional Chinese medicine composition has the advantages that various Chinese herbal medicine materials of the traditional Chinese medicine composition are reasonably combined, medicine effect can be brought into full play, and the traditional Chinese medicine composition is low in cost and free of side effect and has effects of dispelling wind and eliminating dampness, clearing away heat and toxic materials, relieving itching, inducing diuresis to alleviate edema, relieving swelling and removing stasis, and the like; the traditional Chinese medicine composition is mainly used for treating the conjunctivitis and especially spring catarrhal conjunctivitis and all anaphylactic eye inflammation, eye eczema and the like with symptoms such as eye itching, conjunctival congestion, secretion increasing, photophoby and lacrimation; clinical medicine effect experiments show that the conjunctivitis cure rate of the traditional Chinese medicine composition reaches up to 86%, and the total effective rate of the traditional Chinese medicine composition is 100%.

The invention discloses a coumarin eye drop and a preparation method thereof, and relates to the technical field of medicine preparation. The coumarin eye drop of the invention comprises a coumarin extract, an eye lubricant: carboxymethyl cellulose, and a buffer: The mixed solution of NaHCO3 and KCl, preservative: benzalkonium bromide, coumarin eye drops of the present invention For the dry eye syndrome of rabbits caused by atmospheric particulate matter PM, coumarin eye drops can improve the effect of dry eye rapidly and obviously. Symptoms and maintenance tear protein components are a safe and effective method for treating dry eye with simple administration routes and few side effects, and patients can persist for a long time. It has wide clinical application and promotion value. And study its intervention mechanism to discuss its receptors, signal transduction pathways, regulatory mechanisms and related clinical applications, which may provide new ways to explore therapeutic strategies for anti-ocular inflammation, neovascular lesions and degenerative eye diseases.

The invention discloses a product for relieving xerophthalmia and yellow spots on the eye ground and a preparation method thereof. The preparation method comprises following steps: evenly mixing and stirring sorbitol, magnesium stearate, critic acid, and edible essence to obtain an additive mixture; evenly mixing the additive mixture with water soluble haematococcus pluvialis astaxanthin, xanthophyll, vitamin A (or zeaxanthin), and vitamin C, stirring, and pressing the mixture to obtain the product. The production technology is simple. The product can be well absorbed and utilized by the humanbody, and can relieve xerophthalmia, yellow spots on the eye ground, and eye inflammation. The preparation process is simple. The cost is low. The preparation method is green, environmentally-friendly and pollution free. Large scale and massive production can be realized. The product does not have any side or toxic effect and is suitable for long-term administration.

The invention provides an ROS-responsive controlled-release ophthalmic preparation and a preparation method thereof, and belongs to the technical field of biological medicines. According to the invention, the ROS-responsive nano-drug carrier is adopted to entrap the active component of the externally applied drug for the eyes to obtain the controlled-release ophthalmic preparation. When the controlled-release ophthalmic preparation encounters high-content reactive oxygen species (ROS) at the eye inflammation part, the wrapping structure of the ROS response type nano-drug carrier is opened, the active ingredients of the external-use eye medicine are released, after inflammation fades, the ROS level is reduced, the ROS opening switch is closed, the release of the active ingredients of the external-use eye medicine is stopped, and the release of the active ingredients of the external-use eye medicine is stopped. Therefore, the controllable release of the active ingredients of the external medicine for eyes is realized. The ROS response type nano-drug carrier can effectively improve the utilization degree of the active ingredients of the eye external medicine, and can reduce or stop releasing after eye inflammation fades, so that side effects of the active ingredients of the eye external medicine on eyes are avoided, and safe and effective treatment of eye diseases is realized.

The invention discloses an eye drop for relieving ocular inflammation and allergic symptoms and a preparation method thereof, and mainly relates to the field of external ophthalmic medicaments. Including the following components by weight percentage: 69% to 99% of purified water, 0.01% to 10% of sodium hyaluronate, 0.01% to 10% of glycyrrhizinate, 0.1% to 5% of sodium chloride, and 0.1% of Beta dextran %~5%, taurine 0.01%~1%, 1,3-butanediol 0.005%~0.2%. The invention does not contain any prohibited ingredients, has no toxic and side effects, is safe and reliable.

The present invention relates to an improved process of manufacturing sterile topical ophthalmic aqueous nanosuspensions of nanocrystals of fluticasone propionate Form A. The sterile topical ophthalmic nanosuspensions are useful in the treatment of eye inflammation conditions such as blepharitis, posterior blepharitis, Meibomian gland dysfunction and dry eye through topical administration of said nanosuspensions to eyelids, eyelashes and eyelid margin.