Eye drops for alleviating ocular inflammation and allergic symptoms and preparation method thereof

An eye drop and inflammation technology, used in the field of eye drops for relieving inflammation and allergic symptoms and their preparation, can solve problems such as sports athletes' caution, achieve no toxic side effects, reduce swelling of the conjunctiva, and reduce the dosage of use. Effect

Active Publication Date: 2021-08-10
吉林省华恩生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, because dextran is a stimulant, sports athletes should use it with caution

Method used

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  • Eye drops for alleviating ocular inflammation and allergic symptoms and preparation method thereof
  • Eye drops for alleviating ocular inflammation and allergic symptoms and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1: A kind of eye drop that alleviates eye inflammation and allergic symptom

[0025] The preparation includes the following components in mass percentage: sodium hyaluronate 0.03%, disodium glycyrrhizinate 0.05%, sodium chloride 0.7%, Beta glucan 0.2%, taurine 0.05%, 1,3-butanedi Alcohol 0.3%, the remaining components are purified water.

Embodiment 2

[0026] Embodiment 2: A kind of eye drop that alleviates eye inflammation and allergic symptom

[0027] The preparation includes the following components in mass percentage: 0.04% sodium hyaluronate, 0.04% glycyrrhizin monoamine, 0.6% sodium chloride, 0.4% Beta glucan, 0.1% taurine, 1,3-butanedi Alcohol 0.3%, the remaining components are purified water.

Embodiment 3

[0028] Embodiment 3: A kind of preparation method of the eye drop that alleviates eye inflammation and allergic symptom

[0029] Use the formula of embodiment 2, and preparation method comprises the steps:

[0030] 1) Add sodium hyaluronate, sodium chloride, and 1,3-butanediol to purified water under stirring, stir until uniformly dispersed, and set aside;

[0031] 2) Add glycyrrhizinate, taurine, and beta glucan to the solution obtained in step 1) under stirring, stir at a constant temperature and homogeneously, and set aside;

[0032] 3) The solution obtained in step 2) is sterilized by filtering through a 0.22um microporous membrane;

[0033] 4) Subpackage the solution obtained in step 3).

[0034] The eye drops for relieving ocular inflammation and allergic symptoms described in the present invention is a transparent liquid with a weak special smell and a pH value of 6.5-7.4. The product should be sealed and stored in a cool and dry place, and can be stored stably for mo...

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Abstract

The invention discloses an eye drop for relieving ocular inflammation and allergic symptoms and a preparation method thereof, and mainly relates to the field of external ophthalmic medicaments. Including the following components by weight percentage: 69% to 99% of purified water, 0.01% to 10% of sodium hyaluronate, 0.01% to 10% of glycyrrhizinate, 0.1% to 5% of sodium chloride, and 0.1% of Beta dextran %~5%, taurine 0.01%~1%, 1,3-butanediol 0.005%~0.2%. The invention does not contain any prohibited ingredients, has no toxic and side effects, is safe and reliable.

Description

technical field [0001] The invention relates to the field of external ocular medicaments, in particular to an eye drop for relieving ocular inflammation and allergic symptoms and a preparation method thereof. Background technique [0002] Common inflammatory and allergic symptoms in ophthalmology include allergic conjunctivitis and vernal conjunctivitis. The types of anti-inflammatory and anti-allergic eye drops mainly include mast cell stabilizers, histamine receptor antagonists, and glucocorticoid eye drops. Auxiliary drugs include vasoconstrictors, nonsteroidal anti-inflammatory drugs, and artificial tears. The principle of action is as follows: (1) Mast cell stabilizer: This type of drug is also called allergic mediator release agent, such as cromolyn sodium eye drops, nedocromil sodium and lodoxamide eye drops. The mechanism of action is to prevent the occurrence of allergic reactions by stabilizing the mast cell membrane and preventing the release of histamine, leuko...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K33/14A61P27/02A61P37/08A61K31/728A61K31/704A61K31/716A61K31/185A61K31/047
CPCA61K9/0048A61K9/08A61K31/047A61K31/185A61K31/704A61K31/716A61K31/728A61K33/14A61P27/02A61P37/08A61K2300/00
Inventor 李春江
Owner 吉林省华恩生物科技有限公司
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