The invention discloses a xanthophyll compound preparation with a powerful eye-protecting effects, which is made from the following raw materials in a certain proportion: xanthophyll, cowberry extracts, taurine, beta-carotin, zeaxanthin and zinc gluconate, in addition with adjuvant materials, and is available in various common forms such as capsules, granules and oral liquids. The main indications of the xanthophyll compound preparation include asthenopia, myopia, amblyopia, hypermetropia, cataract, macular degeneration, vitreous opacity, retinitis pigmentosa and diabetic retinopathy. The xanthophyll compound preparation contains compound ingredients, has a significant curative effect and is very worthy to be promoted.