161 results about "Cycleanine dimethobromide" patented technology

The invention discloses an inorganic material hybrid hard melamine polyurethane foam heat insulation material, a preparation method thereof and combined polyether used therein. The combined polyether comprises: a polyol flame retardant, hydroxyl calcium phosphate, an inorganic material compounded with hydroxyl calcium phosphate, glycerin, N, N, N, N, N-pentamethyl diethylenetriamine, dimethyl cyclohexyl amine, 33+ / -1Wt.% triethylene diamine's dipropylene glycol solution, organic tin, hexahydro triazine, a foaming agent 141B, water, and silicone oil AK-158. The preparation method includes: mixing the combined polyether with isocyanate in ratio, and then carrying out spraying or casting foaming moulding, thus forming the heat insulation material. The heat insulation material has the characteristics of stable physical performance, no deformation, no shrinkage, strong bonding force, low thermal conductivity, an oxygen index up to over 30%, and a combustion heat release rate increase index of less than 250W / S.

The invention provides a preparation method for 3-aminomethyl-3,5,5-trimethylcyclohexyl amine. According to the preparation method, imidization reaction materials containing 3-cyano-3,5,5-trimethylcyclohexyl imine is subjected to first-stage hydrogenation reaction under the help of a cycled material of a subsequent step, so that a first hydrogenation reaction material is obtained, and also generation of HCN-removed products is effectively inhibited, then a second-stage hydrogenation reaction is performed under the effect of a heating-degradable alkali auxiliary agent, then heating is performed to decompose the alkali auxiliary agent, a part of degraded materials is taken as the cycled material and is returned to the first-stage hydrogenation reaction as an auxiliary agent, and the residual part is subjected to third-stage hydrogenation reaction, so that 3-aminomethyl-3,5,5-trimethylcyclohexyl amine is obtained, and the content of 3-cyano-3,5,5-trimethylcyclohexyl amine and secondary amine products is effectively reduced.

The invention provides a method for preparing bromhexine hydrochloride, which comprises the steps as follows: (1) 2-amino-3,5-dibromo benzaldehyde and reducing agents are in a reduction reaction to generate 2-amino-3,5-dibromo benzyl alcohol; (2) 2-amino-3, 5-dibromo benzyl alcohol that is obtained in the step (1) reacts with chlorinating agents to generate 2, 4-bromine-6-chloride methylaniline; and (3) 2,4-bromine-6-chloride methylaniline obtained in the step (2) and N-methylcyclohexylamine are in an amination reaction, and then 2, 4-bromine-6-chloride methylaniline and HCl salification agents are in a salification reaction, so that bromhexine hydrochloride is obtained. The preparation method adopts multiple advanced technologies, is easy to get starting materials, and has the advantages of stable property of intermediates, extremely low environment pollution, high yield coefficient of products and high purity.

The invention discloses a full-water-type combined polyether and an application method thereof. The full-water-type combined polyether comprises polyether polyol SA380, polyether polyol 310, a foam stabilizer, N,N-dimethylcyclohexylamine, N,N-dimethylbenzylamine and water. The invention also discloses a composition for preparing polyurethane rigid foam. The full-water-type combined polyether disclosed by the invention overcomes the defect that Freon foaming agents used in the existing combined polyether can produce irreversible pollution in the environment, and the defects of foam deformation, higher brittleness and the like when water is used as the foaming agent. The invention provides a full-water-type combined polyether which uses water as the foaming agent; and the prepared combined polyether has the advantages of favorable thermal conductivity, excellent dimensional stability, excellent flowability, excellent demoldability and high compression strength, is especially suitable to be used as a heat insulating material in the field of solar water heaters, and has obvious environmental-protection advantage and social benefit.

The present invention discloses a method for preparing 3-aminomethyl-3,5,5-trimethyl cyclohexylamine(isophorone diamine, IPDA) from 3-cyan-3,5,5-trimethyl cyclohexanone(IPN). The method comprises the following steps 3-cyan-3,5,5-trimethyl cyclohexanone, ammonia, an alcohol and / or ether solvent, a hydrogenation catalyst and a promoter are reacted at a temperature of between 50 and 120 DEG C and a hydrogen pressure of between 5 and 15 MPa so as to obtain 3-aminomethyl-3,3,3-trimethyl cyclohexylamine. The method simplifies the prior process for preparing IPDA from IPN, is low in equipment cost, mild in reaction conditions and high in offspring yield.

The invention relates to an improved process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine, referred to hereinafter as isophoronediamine or, in abbreviated form, IPDA, by: I. preparation of isophorone by catalyzed aldol condensations with acetone as reactant; II. Reaction of isophorone with HCN to form isophoronenitrile (IPN, 3-cyano-3,5,5-trimethylcyclohexanone); III. catalytic hydrogenation and / or catalytic reductive amination (also referred to as aminative hydrogenation) of 3-cyano-3,5,5-trimethylcyclohexanone, hereinafter called isophoronenitrile or, in abbreviated form, IPN, to give the isophoronediamine.

The invention provides a method for preparing 3-aminomethyl-3,5,5-trimethyl cyclohexylamine. The method includes: a) reacting 3-cyano-3,5,5-trimethyl cyclohexanone with excess primary amine, while removing water of the reaction, so that IPN is substantially completely converted to an imine compound; b) in the presence of an aminolysis catalyst, mixing the resulting product from step a) with liquid ammonia so as to carry out the aminolysis reaction on the imine compound to form 3-cyano-3,5,5-trimethyl cyclohexylimine and the primary amine; and c) performing the hydrogenation reaction to 3-cyano-3,5,5-trimethyl cyclohexylimine obtained in step b) to get 3-carbamoylyl-3,5,5-trimethyl cyclohexylamine in the presence of hydrogen and a hydrogenation catalyst. The method of the present invention prevents the generation of major byproducts of 3,5,5-trimethyl cyclohexanol, and 3-aminomethyl-3,5,5-trimethyl cyclohexanol in the prior art, thereby improving the yield of 3-aminomethyl-3,5,5-trimethyl cyclohexylamine.

The invention discloses a production method of bromhexine hydrochloride, which uses a multi-function reaction kettle with a special kettle bottom valve as the reaction vessel, uses a special filter as the purifier, uses 2-nitrobenzyl bromide and N-methyl cyclohexylamine as the starting materials, enables the product generated by the reaction under the condition of normal temperature and pressure to the react with hydrazine hydrate under the catalysis of Raney's nickel, and produces the bromhexine hydrochloride by brominating substitution reaction, chlorine hydride salification reaction, purification and drying. Compared with the disclosed production process of bromhexine hydrochloride and the bromhexine hydrochloride produced by the current synthesis device, the production method of the invention has the advantages of less reaction steps, moderate reaction condition, convenient purification and simple operation; the used special device has the advantages of good heat insulation, oxidation resistance, air tightness and environmental protection effects and thorough reaction; and the reaction device has the advantages of simple structure, convenient operation, easy disassembly / assembly and cleaning, high filter efficiency, reaction quality and yield, and stable product quality.

The invention discloses a composition, a hard polyurethane foam material and refrigerating equipment. The composition is prepared from the following components including premixed polyether polyol and isocyanate, wherein the premixed polyether polyol contains polyol, a foaming agent and a catalyst composition, the foaming agent contains trans 1-chloro-3,3,3-trifluoropropene, and the catalyst composition contains 1,2-dimethylimidazole, N,N-dimethyl cyolohexlemine and (2-hydroxypropyl) trimethyl ammonium formate. The composition has stability during long-term storage. In addition, the foam material obtained by adopting the composition has the characteristics of good demoulding, strong adhesion, low thermal conductivity and the like, so that the obtained product is good in energy saving effect.

The invention discloses composite polyether, composition including the composite polyether and polyurethane block foam and a preparing method and application of the composite polyether. The composite polyether includes, by weight, 4 parts to 6 parts of polyether polyol A, 3 parts to 4 parts of polyether polyol B, 1 part to 2 parts of polyether polyol C, 02 part to 0.4 part of surface active agent, 0.2 part to 0.4 part of catalyst, 1 part to 2 parts of foaming agents and 0.2 part of water, wherein the surface active agent is B8545 and LK665, and the catalyst is N,N-dimethyl cyclohexylamine 1,3,5-3 (dimethylamino propyl)-hexahydro triazine and TMR-2. The density of the rigid polyurethane block foam prepared from the composite polyether is uniform, a heat conductivity coefficient is small, foam is exquisite, dimensional stability is high, compression strength is high, and mould opening production and fast demolding can be performed when the rigid polyurethane block foam is prepared.

A process for the cyanoethylation of substituted cycloaliphatic vicinal diamines which comprises reacting acrylonitrile and a diamine in the presence water as catalyst. Cyanoethylated methylcyclohexylamines are readily prepared in the presence of water.

The invention provides a preparation method and application of N, N-dimethyl-3, 3, 5-trimethyl cyclohexylamine. The method comprises enabling 3, 3, 5-trimethyl cyclohexylamine, formaldehyde and hydrogen to undergo an amination hydrogenation reaction under a fixed temperature and pressure under the effect of a catalyst so as to prepare N, N-dimethyl-3, 3, 5-trimethyl cyclohexylamine. The obtained N, N-dimethyl-3, 3, 5-trimethyl cyclohexylamine can be used as a catalyst for polyurethane foaming after purification.

The invention discloses a preparation method and application of a Co and Al2O3 compound nanotube array membrane catalyst. The method comprises the following steps of: carrying out constant-pressure anodic oxidation in a urea-containing electrolyte by taking a Co-Al alloy sheet as an anode and high-purity graphite or an other conducting material as a cathode to prepare an alloy sheet with a Co and Al2O3 compound nanotube array membrane grown on a surface; then crushing the obtained alloy sheet into alloy granules, namely catalyst precursors; reducing the catalyst precursors by using H2 to obtain the Co and Al2O3 compound nanotube array membrane catalyst with uniform apertures, smooth tube walls, controllable pipe lengths and consistent pore path directions. The novel catalyst disclosed by the invention is used for preparing 3-aminomethyl-3,5,5-trimethyl cyclohexylamine (IPDA) by carrying out catalytic hydrogenation on 3-cyano-3,5,5-trimethyl cyclohexanone (IPN) and can achieve the maximal transformation rate of IPN by 100% and achieve the maximal selectivity of IPDA more than 98%.

The invention discloses a hard polyurethane foam plastic in the insulating pipe layer, which is characterized by the following: adopting plural polyether, catalyst, foam stabilizer, distill water and foamer to form component A; using polymethylene polyphenyl polyisocyanates as raw material B; selecting triethanolamine, N, N-dimethyl cyclohexylamine, 2, 4, 6-tri (dimethylamine methyl) phenol and potassium oleate as catalyst; blending component A and B evenly; stirring; pouring the mass into mould; foaming; solidifying; obtaining the product with stable size for SY / T0415-96 standard.

A molecular sieve comprises at least one intergrown phase of an AFX framework-type molecular sieve and a CHA framework-type molecular sieve and is conveniently synthesized using a combination of N,N,N′N′-tetramethylhexane-1,6-diamine and N,N-dimethylcyclohexylamine as organic directing agents.

The invention relates to a composite vinylamine-series weakly-basic anion exchange resin and a method for recovering rhenium from waste acid produced in copper smelting, belonging to the technical field of recycling of metallic rhenium. The composite vinylamine-series weakly-basic anion exchange resin is prepared by swelling chloromethylated polystyrene microspheres in an organic solvent for 4 to 10 h; then slowly adding a mixture of dicyclohexylamine, pyridine and N-methylcyclohexylamine and carrying out a reaction at room temperature for 1 to 6 h; then carrying out heating to 40 to 90 DEG C and continuing the reaction for 6 to 18 h; and then carrying out vacuum pumping filtration. The composite vinylamine-series weakly-basic anion exchange resin provided by the invention has good adsorptive selectivity on low-concentration rhenium (2 to 10 mg / L) under the conditions of high acidity and existence of high-concentration impurity ions, and almost does not adsorb impurity ions, especially toxic arsenate ions; waste acid directly enters an arsenate after filtering; so process flow is simplified and the recovery rate of rhenium is increased.

The invention discloses a method for preparing 3-aminomethyl-3,5,5-trimethyl cyclohexylamine (IPDA) by using 3-cyano-3,3,5-trimethylcyclohexanone (IPN), which comprises: a) reacting the 3-cyano-3,3,5-trimethylcyclohexanone with formic acid and ammonia or with ammonium formate) at 140 to 180 DEG C in an organic solvent to obtain the 3-cyano-3,5,5-trimethyl cyclohexylamine; and b) performing a reduction reaction of the 3-cyano-3,5,5-trimethyl cyclohexylamine and a hydrogen anion-containing compound at 20 to 50 DEG C to obtain 3-aminomethyl-3,5,5-trimethyl cyclohexylamine. The method can prepareIPDA under simple and convenient conditions.

The invention discloses a method for preparing 3-aminomethyl-3, 5, 5-trimethyl cyclohexylamine (isophorone diamine, IPDA) by 3-cyano-3, 5, 5-trimethyl cyclohexanone (IPN, isophorone nitrile), which comprises the following steps: a) 3-cyano-3, 5, 5-trimethyl cyclohexanone and oxyammonia are arranged in an organic solvent for reaction under a temperature ranging from 40 DEG C to 80 DEG C, and 3-cyano-3, 5, 5-trimethyl cyclohexanone oxime is generated; b) 3-cyano-3, 5, 5-trimethyl cyclohexanone oxime, hydrogen and liquid ammonia are arranged in an organic solvent for reaction under a temperature ranging from 50 DEG C to 120 DEG C, a total pressure ranging from 5 MPa to 15 MPa and the effect of a hydrogenation catalyst, and 3-aminomethyl-3, 5, 5-trimethyl cyclohexylamine is obtained. The method has the advantages that, the production of a by-product 3-aminomethyl-3, 5, 5-trimethyl cyclohexanol (IPAA) which is hard to be separated from IPDA is avoided; simultaneously, the amount of liquid ammonia is largely decreased.

The invention provides a preparation method of a rigid polyurethane foam heat insulation and energy saving material. The preparation method comprises the following steps of S1, preparing a black material and a white material with the weight ratio being (1.1-1.2) to 1, wherein the black material is isocyanate, and the white material is prepared by mixing the following raw materials in parts by weight: 70-95 parts of polyether polyol, 15-25 parts of deionized water, 6-9 parts of expanded vermiculite, 3-6 parts of acrylic resin, 2-3 parts of organosilicon oil foam stabilizer, 3-6 parts of rock wool fiber, 2-6 parts of bagasse fiber, 5-9 parts of nanometer calcium carbonate, 0.1-0.3 part of N,N-dimethyl cyclohexyl amine and 4-6 parts of modified tin catalyst; and S2, uniformly mixing the whitematerial in advance, then mixing the black material and the white material, foaming a mixture with a high-pressure foaming machine, injecting a foamed product into a die, and performing formation toobtain the rigid polyurethane foam heat insulation and energy saving material. The preparation method can reduce use of a chemical solvent and improves the heat insulation performance of a whole polyurethane material at the same time.

The invention discloses a composition, rigid polyurethane foam and a refrigeration device. The composition comprises combined polyether and isocyanate, wherein the combined polyether contains polyol, a foaming agent and a catalyst composition, wherein the foaming agent contains trans-1-chloro-3, 3, 3-trifluoropropene, and the catalyst composition contains N-methyldicyclohexylamine, N, N-dimethylcyclohexylamine and (2-hydroxypropyl) trimethylammonium formate. The composition has long-term storage stability; and furthermore, the foam material obtained by adopting the composition has the characteristics of low heat conduction coefficient, high strength, short curing time and the like, so that an obtained product has a relatively good energy-saving effect.

The invention discloses a chemical synthesis method, in particular a synthesis method for continuously producing N,N-dimethyl cyclohexyl amine, taking cyclohexanol and dimethylamine as raw materials and carrying out closed loop circulation in the whole process. In the chemical synthesis method, the reaction is performed by taking Co / Al2O3 as a catalyst, and controlling the pressure, the temperature, the mol ratio of the cyclohexanol to the dimethylamine and the consumption of the catalyst to 0.01-3.5m3 / (hr*m3 catalyst); condensing and the cooling, gas-liquid separation and gas phrase recycling are carried out on the reacted materials; and liquid phrase enters a rectification tower for separating and purifying the N, N-dimethyl cyclohexyl amine to obtain the finished product. The synthetic method has the advantages of simple flow, easy operation, high conversion rate of raw materials, good selectivity of products, few byproducts, simple separation flow, low consumption of the raw materials, obvious environment-friendly effect, low production cost of the products and convenience for industrial large-scale production.

The invention discloses a special shrinkage reducing agent for concrete mortar. The special shrinkage reducing agent for the concrete mortar belongs to the technical field of building material auxiliaries, and is prepared from a modified starch emulsion, a lightweight aggregate, N,N-dimethyl cyclohexyl amine, calcium bicarbonate, a water reducing agent, a defoaming agent and an air entraining agent, wherein the modified starch emulsion is obtained through stirring and mixing octenyl succinic acid modified starch and water, adding oil liquid, continuously stirring and mixing, dispersing at highspeed, and homogenizing at high pressure. The special shrinkage reducing agent for the concrete mortar is prepared through stirring and mixing the modified starch emulsion, the lightweight aggregate,the N,N-dimethyl cyclohexyl amine and the calcium bicarbonate, adding the water reducing agent, the defoaming agent and the air entraining agent, continuously stirring and mixing, discharging and filling. The special shrinkage reducing agent for the concrete mortar provided by the invention has an excellent reducing performance.

The invention discloses a high-flame retardation polyurethane composite heat insulation plate. The high-flame retardation polyurethane composite heat insulation plate comprises two backing layers and a polyurethane heat insulation layer positioned between the two backing layers, the polyurethane heat insulation layer is made of a high-performance polyurethane foam material, and raw materials of the high-performance polyurethane foam material comprise polyether polyol, polyphenylpolymethylene polyisocyanate, hexamethylene diisocyanate, polyacrylate, liquid styrene butadiene rubber, cyclohexylamine, N,N-dimethylcyclohexylamine, dibutyltin dilaurate, methyl formate, water, hydroxy silicone oil, a fire retardant, expanded perlite, hollow glass micro-beads, pentaerythritol and sorbitol; and raw materials of the fire retardant comprise nanometer aluminum hydroxide, nanometer magnesium hydroxide, melamine phosphate, expandable graphite, hydroxy silicone oil, and a phosphamide fire retardant. The high-flame retardation polyurethane composite heat insulation plate has the advantages of high strength, excellent heat and flame retardation, and long service life.

The invention relates to N,N-dimethyl-4-cyclohexylaminomethylcyclohexane as well as a preparation method and application thereof. The method comprises the following step of preparing the N,N-dimethyl-4-cyclohexylaminomethylcyclohexane by utilizing a byproduct deammoniated light component in an HMDA (Hexamethylene Diamine) reaction process, formaldehyde and hydrogen gas under the action of a catalyst and under certain temperature and pressure through hydrogenation and methylation. After being purified, the obtained N,N-dimethyl-4-cyclohexylaminomethylcyclohexane can be used as a polyurethane catalyst; effective utilization of an HMDA byproduct is realized and polyurethane foam prepared from the N,N-dimethyl-4-cyclohexylaminomethylcyclohexane has the advantages of low odor, good physical properties and the like.

The invention discloses a preparation method for bromhexine hydrochloride. The preparation method comprises the following steps of: reacting acetic anhydride with boric acid to generate triacetic acid boric acid ester; reacting 2-amino-3,5- dibromo benzylalcohol with triacetic acid boric acid ester to generate 2-amino-3,5-dibromo benzylalcohol boron chelate; reacting 2-amino-3,5-dibromo benzylalcohol boron chelate with N- methylcyclohexylamine to generate N-(2-amino-3,5-dibromobenzyl)-N-methylcyclohexylamine (bromhexine); and reacting bromhexine with hydrogen chloride to generate crude bromhexine hydrochloride, and refining to obtain refined bromhexine hydrochloride. The bromhexine hydrochloride is suitable for treating chronic bronchitis and other respiratory diseases with phlegm which is difficult to cough out.

The invention discloses a method for preparing N,N-dimethylcyclohexylamine and N-methyl-dicyclohexylamine, which comprise the following steps: under certain reaction temperature and pressure condition, cyclohexanone, ammonia, hydrogen and formaldehyde pass through a two-stage reactor to obtain the N,N-dimethylcyclohexylamine and N-methyl-dicyclohexylamine. The method has the advantages of easily available raw material with low cost, high conversion rate, good product selectivity, little by-product, simple flow, and low production cost, N-methyl-dicyclohexylamine with high added value can be obtained through combined production, product composition can be adjusted by changing the reaction condition according to the market demand condition of the product, and the method is suitable for industrial large scale production.

The invention relates to a production method of bromhexine hydrochloride. The production method is characterized by comprising the following steps of: 1) carrying out a condensation reaction between 3,5-dibromo-2-aminobenzalcohol and N-methyl cyclohexane in the presence of glacial acetic acid as a catalyst, thereby generating N-methyl-N-cyclohexyl-2-amino-3,5-dibromobenzylamine; 2) salifying the generated N-methyl-N-cyclohexyl-2-amino-3,5-dibromobenzylamine with hydrochloric acid to obtain bromhexine hydrochloride; and 3) decoloring and refining the obtained bromhexine hydrochloride in an alcoholic solution to obtain a pure product, wherein an azeotropic water-carrying agent is added to the condensation reaction in the step 1), and water in the reaction mixed solution in the reaction process is removed immediately through distillation.

The invention relates to a hydroquinone hydrogenation catalyst, a preparation method and a hydrogenation reaction method. The catalyst contains an active ingredient of Ru, an auxiliary agent La and a carrier, wherein the composition of the catalyst is shown as x percent Ru-y percent La / carrier, wherein the x percent Ru-y percent La / carrier, wherein the x percent represents the mass percentage of the Ru in the catalyst; the y percent represents the mass percentage of the La in the catalyst; the content of each ingredient of the catalyst is shown as follows: the mass percentage of Ru is 0.5 to 5 percent; the mass percentage of La is 0.2 to 2 percent; the rest is the carrier. Catalyst precursors are prepared by an immersion-precipitation method; then, the catalyst precursors are reduced in the hydrogen-containing atmosphere; the para-nitrotoluene hydrogenation Ru-La bimetal catalyst is obtained; in the reaction for preparing p-methyl-cyclohexylamine through nitrotoluene hydrogenation, the p-methyl-cyclohexylamine can be strongly adsorbed onto the catalyst; a great amount of tar can be further generated; the proceeding of the reaction is inhibited; through the addition of the La, the problem of strong adsorption of the catalyst on the p-methyl-cyclohexylamine is well solved; the tar generation quantity is reduced.

A molecular sieve comprises at least one intergrown phase of an AFX framework-type molecular sieve and a CHA framework-type molecular sieve and is conveniently synthesized using a combination of N,N,N′N′-tetramethylhexane-1,6-diamine and N,N-dimethylcyclohexylamine as organic directing agents.