83 results about "Brain aging" patented technology

Compositions comprising one or more unsaturated fatty acids and one or more nitric oxide releasing compounds, and methods for using such compositions for enhancing cognitive function, reducing or preventing a decline of social interaction, reducing or preventing age-related behavioral changes, increasing trainability, maintaining optimal brain function, facilitating learning and memory, reducing memory loss, retarding brain aging, preventing or treating strokes, and preventing or treating dementia in an animal. Preferably, the compositions are food compositions useful for enhancing cognitive function in humans and companion animals.

The invention relates to a chaffy dish base flavoring, and specifically relates to a nutritive chaffy dish base flavoring. The invention belongs to the field of foodstuff processing. According to the invention, spinach is added to the base flavoring. Spinach contains a large amount of beta carotene and iron, and is also an excellent source of vitamin B6, folic acid, iron and potassium. Spinach contains a large amount of anti-oxidants such as vitamin E and selenium element. Spinach has functions of aging resisting, cell proliferation promoting, brain function activating, vigor enhancing, brain aging preventing, and Alzheimer's disease preventing. Also, spinach has an antihypertensive effect, such that the base flavoring is suitable for the elderly to eat. According to the invention, xylitol is used for replacing edible sugar, such that the sugar content of the base flavoring is reduced. The base flavoring is suitable for various populations to eat, and has a nutritive function.

The invention discloses a fetal brain age estimation and anomaly detection method and device based on deep learning. The brain age estimation and anomaly detection method comprises the following steps: firstly, establishing a data set of T2 weighted magnetic resonance images of the brain of a normal fetus by utilizing T2 weighted images in the uterus of a pregnant woman, which are collected clinically and conventionally; secondly, segmenting the brain of the fetus from the uterus by using a U-shaped network, predicting the brain age of the fetus by using a deep residual network based on an attention mechanism, and generating the uncertainty of the brain age and the credibility of the estimation of the brain age of the fetus; and finally, constructing a classifier according to the difference, uncertainty, credibility and other indexes of the actual fetal age and the predicted brain age, and judging whether the brain development of the fetus is abnormal or not. According to the method, the brain age of the fetus can be estimated at the same time, indexes such as uncertainty and estimation credibility are generated to be used for detecting the fetus with abnormal brain development, and the method and device have high accuracy and precision and high clinical application prospect and value.

The invention discloses a novel application of red stilbene and red stilbene polysaccharide in preparing medicament for treatment of Alzheimer disease. Red stibene and red stilbene polysaccharide in the invention can protect SH-SY5Y cells from the damage from A beta 25-35, and increase the viability of SH-SY5Y cells. The Morris water maze test indicates that red stibene and red stilbene polysaccharide can improve the cognitive dysfunction of mice with rapid brain aging and rats injected with A beta and AD in the hippocampus. Further histology detection indicates that red stilbene and red stilbene polysaccharide can increase the contents of center neurotransmitters 5-HT, 5-HIAA, NE and DA in rapid aging mice brain, wherein the neurotransmitters are monoamines.

The invention provides noodles capable of improving intelligence of children and a preparation method thereof. The noodles are prepared from flour, sharpleaf galangal fruit, walnut kernels, black beans and Chinese dates, are rich in nutrients, can promote development of brain cells after being frequently eaten, have the effects on improving intelligence, strengthening brains, delaying brain aging and improving memory, do not contain any strengthening agents, preservatives, chemical synthetic pigments or other chemical substances, are pure in taste, have good pliability and elasticity, are not sticky when eaten, do not make soup turbid easily, have long shelf lives and are purely natural nutritious food.

The invention discloses a traditional Chinese medicine for treating Alzheimer disease as well as a preparation method and application thereof. The traditional Chinese medicine comprises the following components in parts by mass: 15 parts of codonopsis pilosula, 15 parts of astragalus mongholicus, 12 parts of rhizoma polygonati, 6 parts of polygonum multiflorum, 10 parts of curcuma aromatica, 8 parts of rhizoma acori graminei, 10 parts of ligusticum wallichii and 8 parts of earthworm. The method comprises the following steps of: adding the curcuma aromatica, the rhizoma acori graminei and the ligusticum wallichii into deionized water, heating for distilling and extracting volatile oil, dehydrating the volatile oil, clathrating with beta-cyclodextrin and drying at low temperature; collecting a distilled water solution with another vessel, adding the codonopsis pilosula, the astragalus mongholicus, the rhizoma polygonati, the polygonum multiflorum and earthworm into water, decorating, mixing decoctions, filtering to obtain filtrate, mixing the filtrate with the distilled water solution, concentrating to obtain concentrate, adding 95% ethanol to the concentrate to ensure that the alcohol precipitation concentration is 60%, fully stirring, standing for 24-48 hours, filtering to obtain filtrate, recovering ethanol from the filtrate, concentrate the filtrate subjected to ethanol removal to form thick paste and performing microwave drying on the thick paste to form a dry extract; and crushing the dry extract, adding a defined amount of dextrin or starch, performing wet granulation, drying and granulation, adding a volatile oil clathrate compound and uniformly mixing. By adopting methods of invigorating spleen and kidney, eliminating phlegm and dispersing blood stasis, the brain premature senility and brain aging are prevented and intervened, thereby delaying the development of the Alzheimer disease, improving the clinical symptoms and improving the life quality of patients.

The invention discloses capsules for improving memory and a preparation method thereof. The preparation method comprises the following step: by taking three medicinal materials namely Chinese magnoliavine fruit, mulberry fruit and barbary wolfberry fruit as main medicines, adding raw materials with functional roles such as DHA dry powder, lecithin, taurine and vitamin E to prepare the capsules. By adopting the capsules disclosed by the invention, situations of memory lapse caused by the factors including brain aging, body function drops or malnutrition and the like of old people can be improved; and meanwhile, the capsules have multiple effects of enhancing cerebral functions, delaying brain aging, improving memory and the like, and are suitable for patients suffering Alzheimer's disease and other persons suffering memory lapse.

The invention discloses a brain age prediction model and method based on an attention mechanism and bilinear fusion. The method comprises the steps of extracting features of an image through a 3D CNNnetwork; then, in order to better enrich the feature expression capability of each pixel point, carrying out bilinear fusion processing on the extracted image features; meanwhile, due to the fact thatan attention mechanism can capture key feature information influencing the brain age and reduces the attention degree of the feature information irrelevant to the brain age, inputting the image features obtained after bilinear fusion processing into an Attention layer, and obtaining the attention weight of the images; obtaining the attention of the images based on the attention weight; and finally, sending the image features to a full connection layer, and performing brain age regression prediction. According to the invention, the accuracy of brain age prediction is improved by using a methodof combining the attention mechanism and bilinear fusion.