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Assessment system for brain ageing

An evaluation system and brain aging technology, applied in the medical field, can solve the problems of complex detection, no examination of whether the tested person deviates from the normal aging track, lack of aging degree of brain function of the elderly, etc., and achieve the effect of simple test requirements and easy operation

Inactive Publication Date: 2018-03-20
PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These technologies all need to rely on large and expensive medical instruments, and the detection is more complicated
[0004] At present, there is no accurate quantitative method for assessing the aging degree of brain function in the elderly, and there is no evaluation method for examining whether the subject deviates from the normal aging trajectory according to the normal aging trajectory of the brain.

Method used

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  • Assessment system for brain ageing
  • Assessment system for brain ageing
  • Assessment system for brain ageing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Embodiment 1 A kind of nervous system aging evaluation system

[0081] A nervous system aging evaluation system includes eye movement inspection equipment and a data processor. The eye movement inspection equipment includes a visual target, an eye movement video acquisition goggle with a camera, a power adapter, and software for eye movement sampling and curve data analysis. Using the eye movement inspection equipment to perform 2 minutes of saccadic eye movement data and 2 minutes of smooth eye movement data, the peak velocity of saccadic eye movement can be obtained, Saccadic Peak Velocity [SacPV]; the accuracy rate of saccadic eye movement, Saccadic Accuracy [SacAcc]; Saccade eye movement reaction time, Saccadic Reaction Time[SacRT]; smooth eye movement gain, Smoothpursuit gain[Smooth] four items of data.

[0082]These four items of data are received and stored by the data processor. In addition, the data processor pre-stores the mathematical model of eye movement ...

Embodiment 2

[0083] Embodiment 2 A nervous system aging evaluation system

[0084] Repeat Example 1 with the following difference, the system also includes a body swing instrument. The body swing instrument contains a traction part and a displacement sensor, one end of the traction part is connected with the displacement sensor, and the other end is used to be tied to the subject. The body swing amplitude can be output through the displacement sensor, body sway [Sway] (ie body swing data), that is, the distance generated by the traction part due to the movement of the subject's center of gravity. For the detailed structure and operation method of the body swing instrument, please refer to Chinese patent 205306959U.

[0085] The body swing instrument is used to test the moving distance of the center of gravity of the subject after being pulled, and output the body swing data, body sway [Sway]. Correspondingly, the data processor is also configured to receive body swing data, pre-store a m...

Embodiment 3

[0086] Example 3 Construction of mathematical model of eye movement data and body swing data changing with age

[0087] 1. Select the test object used to build the model

[0088] A total of 133 healthy subjects were selected, including Chinese healthy young adults (18-40 years old) and Chinese healthy middle-aged and elderly people (41-80 years old). Test subjects are willing to participate in this study. No history of cognitive impairment, no history of serious physical disease. There was no previous history of neurological diseases or psychiatric diseases, no external ophthalmoplegia, ptosis, hemifacial spasm, or severe vision abnormalities. MMSE ≥ 26 points (to exclude patients with mild cognitive impairment and dementia, subjects with education ≥ 8 years must also have MoCA score > 26 points, and subjects with education 22 points), neurological specialist physical examination showed no obvious abnormalities, no obvious mental and behavioral abnormalities, and normal act...

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Abstract

The invention belongs to the field of medicine, and relates to an assessment system for assessing brain ageing through eye movement and body swing. Eye movement inspection equipment is adopted for thesystem to acquire eye movement data. Eye movement data of healthy population is used to establish a math model through a data manager. The system can further comprise a body oscillometer which is used for acquiring body swing data. According to the assessment system, a model which takes simple and quick quantitative eye movement data and body swing data as the basis and reflects that the functionof the nervous system of the human is continuously changed with age is first provided, data of testees is integrated to an eye movement inspection value distribution chart, predicted by the model, ofold people at different age groups, and the illness conditions of individuals are predicted; the problems of late discovery and difficult diagnosis of degenerative diseases of the nervous system aresolved, the system helps to diagnose and treat the degenerative diseases in the early stage and benefits patients and their families to a certain degree, and the social economic burden brought by thediseases is reduced.

Description

technical field [0001] The invention belongs to the medical field and relates to a brain aging evaluation system for diagnosing or predicting neurodegenerative diseases. Background technique [0002] With age, the brain function of human beings is gradually aging, and some neurodegenerative diseases common to the elderly will also appear, such as Alzheimer's disease, Parkinson's disease, and multiple system atrophy. Most of these diseases have hidden onset, progressive aggravation, great disabling and fatality, and bring heavy life and economic burdens to patients and their families, and have become one of the most important socioeconomic problems in today's society. . Due to the general lack of understanding of these neurodegenerative diseases, ordinary people, and even some non-specialized medical workers, often attribute some of the early manifestations of the above diseases, such as memory loss and slow movement, to normal brain aging manifestations of the elderly . T...

Claims

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Application Information

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IPC IPC(8): A61B5/00A61B5/11
CPCA61B5/1128A61B5/4088A61B5/72A61B2576/026
Inventor 陈霞任宇鹏江骥胡蓓江昊
Owner PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI
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