34 results about "Inhibitory neurotransmitter" patented technology

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The technology involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and / or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and / or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

A traditional Chinese medicine preparation for treating epilepsia comprises poria cocos, rhizoma cyperi, curcuma zedoary, pericarpium citri reticulatae viride, platycladi seed, rhizoma corydalis, rhizoma acori graminei, gastrodia elata, periostracum cicada, polygala tenuifolia, glossy privet fruit, cortex albiziae, tuber fleeceflower stem, codonopsis pilosula, salviae miltiorrhizae, radix paeoniae alba, spina date seed, raw oyster shell, uncaria rhynchophylla, frankincense, scorpion, leech, silkworm larva, ground beeltle and arisaema cum bile. The traditional Chinese medicine preparation integrates brain function improvement, traditional Chinese medicine recuperation and epilepsia resistance, treats both principal and secondary aspects of a disease through normal flora growth fostering, organism immune enhancement, inhibitory neurotransmitter gamma amino butyric acid (GABA) content improvement, controls symptoms of epilepsia, enables damaged cranial nerves to be repaired and regenerated, and utilizes interaction of a medicine to offset or withstand side effects of western medicines. The epilepsia is not prone to reappear.

Devices, systems and methods are disclosed for electrical stimulation of the vagus nerve to treat or prevent disorders in a patient. The methods comprise transmitting impulses of energy to the vagus nerve according to a treatment paradigm that includes single doses of 30 seconds to 5 minutes of continuous stimulation. The treatment paradigm further comprises one or more daily treatment sessions that each include one or more doses for prophylactic or acute treatment of the patient's condition. Vagus nerve stimulation is used to modulate the release of inhibitory neurotransmitters in the brain, such as GABA, norepinephrine, and / or serotonin.

Devices, systems and methods are disclosed for electrical stimulation of the vagus nerve to treat or prevent disorders in a patient. The methods comprise transmitting impulses of energy to the vagus nerve according to a treatment paradigm that includes single doses administered 2 to 5 times per day. The treatment paradigm may further comprise one or more daily treatment sessions that each include one or more doses for prophylactic or acute treatment of the patient's condition. Vagus nerve stimulation is used to modulate the release of inhibitory neurotransmitters in the brain, such as GABA, norepinephrine, and / or serotonin.

The invention provides an anxiolytic drug and a preparation method thereof, wherein the anxiolytic drug is prepared by the following raw materials in parts by weight: 5-25 parts of rhodiola rosea, 5-15 parts of hypericum perforatum, 5-15 parts of gastrodia elata, and 5-18 parts of rehmanniae vaporata. The anxiolytic drug has the advantages of reasonable formulation, simplicity in preparation and obvious effect. The animal experiment indicates that the anxiolytic drug can obviously enhance the secretion level of inhibitory neurotransmitter in serum, namely reanal GABA, obviously enhances the anxiolytic action capacity of mice, and has no side effects to affect learning and memory abilities after being taken for a long term.

The invention provides a GABA and electrophysiological micro-nano synchronous sensing detection chip and a preparation method thereof. The micro-nano synchronous sensing detection chip comprises a substrate layer, a conductive layer and an insulating layer, wherein the substrate layer is made of a flexible material and covers a bottom support; the conductive layer is formed on the substrate layerand used for synchronously detecting changes of inhibitory neurotransmitter GABA and neuroelectric signals in multiple different sub-regions of a rat hippocampus structure; the conductive layer comprises detection site groups which are distributed at positions matching with the size of the rat hippocampus structure and distributed in different sub-regions of the rat hippocampus structure in a radiation manner along the diagonal direction of a detection region; and the insulating layer is made of a flexible material and is formed on the substrate layer except the area where the detection site groups are located. According to the invention, the inhibitory neurotransmitter and the electrical signals can be synchronously detected, and a microprocessing technology, a nanometer material and a biologically sensitive film technology are combined, so the neural information network and the pathogenesis of neurodegenerative diseases can be easily found and understood.

The disclosure provides a GABA and electrophysiological micro-nano synchronous sensing detection chip and a preparation method thereof, wherein the micro-nano synchronous sensing detection chip includes: a base layer, a conductive layer and an insulating layer; the base layer is a flexible material, and the base layer Overlaid on the bottom support; the conductive layer is formed on the base layer, and is used to synchronously detect the changes of the inhibitory neurotransmitter GABA and nerve electrical signals in many different sub-regions of the hippocampal structure of the rat; the conductive layer includes: detection sites group, the distribution position matches the size of the rat hippocampus, and the detection site group radiates along the diagonal direction of the detection area and is distributed in different sub-regions of the rat hippocampus; the insulating layer is a flexible material, and the insulating layer is formed on the On the basal layer outside the region where the group of detection sites is located. The disclosure can simultaneously detect inhibitory neurotransmitters and electrical signals, combined with micro-processing technology, nano-materials and bio-sensitive thin film technology, to help discover and understand neural information networks and the pathogenic mechanism of biblical degenerative diseases.

Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The methods provide damaged interstitial cells of Cajal (ICC) with trophic factors via vagal afferent nerve fibers, thereby reversing ICC damage, and as a consequence improving gastric motility. The methods also increase levels of inhibitory neurotransmitters in the brain so as to decrease neural activity within the area postrema, or they deactivate a resting state neural network containing parts of the anterior insula and anterior cingulate cortex, which will thereby reduce abnormal interoception and visceral hypersensitivity.

The invention provides an anxiolytic drug and a preparation method thereof, wherein the anxiolytic drug is prepared by the following raw materials in parts by weight: 5-25 parts of rhodiola rosea, 5-15 parts of hypericum perforatum, 5-15 parts of gastrodia elata, and 5-18 parts of rehmanniae vaporata. The anxiolytic drug has the advantages of reasonable formulation, simplicity in preparation and obvious effect. The animal experiment indicates that the anxiolytic drug can obviously enhance the secretion level of inhibitory neurotransmitter in serum, namely reanal GABA, obviously enhances the anxiolytic action capacity of mice, and has no side effects to affect learning and memory abilities after being taken for a long term.

A traditional Chinese medicine preparation for treating epilepsia comprises poria cocos, rhizoma cyperi, curcuma zedoary, pericarpium citri reticulatae viride, platycladi seed, rhizoma corydalis, rhizoma acori graminei, gastrodia elata, periostracum cicada, polygala tenuifolia, glossy privet fruit, cortex albiziae, tuber fleeceflower stem, codonopsis pilosula, salviae miltiorrhizae, radix paeoniae alba, spina date seed, raw oyster shell, uncaria rhynchophylla, frankincense, scorpion, leech, silkworm larva, ground beeltle and arisaema cum bile. The traditional Chinese medicine preparation integrates brain function improvement, traditional Chinese medicine recuperation and epilepsia resistance, treats both principal and secondary aspects of a disease through normal flora growth fostering, organism immune enhancement, inhibitory neurotransmitter gamma amino butyric acid (GABA) content improvement, controls symptoms of epilepsia, enables damaged cranial nerves to be repaired and regenerated, and utilizes interaction of a medicine to offset or withstand side effects of western medicines. The epilepsia is not prone to reappear.