44 results about "Biophoton" patented technology

Disclosed are methods and systems for subnanosecond rise time high voltage (HV) electric pulse delivery to biological loads. The system includes an imaging device and monitoring apparatus used for bio-photonic studies of pulse induced intracellular effects. The system further features custom fabricated microscope slide having micro-machined electrodes. A printed circuit board to interface the pulse generator to the micro-machined glass slide having the cell solution. An low-parasitic electronic setup to interface with avalanche transistor-switched pulse generation system. The pc-board and the slide are configured to match the output impedance of the pulse generator which minimizes reflection back into the pulse generator, and minimizes distortion of the pulse shape and pulse parameters. The pc-board further includes a high bandwidth voltage divider for real-time monitoring of pulses delivered to the cell solutions.

Following exposure to an external light source, determining: 1) the fertility of an avian egg by measuring the photon intensity (photons per second) of the egg's biophoton and luminescence; and 2) the gender of an avian egg by measuring the photon spectrum of the egg's biophoton emission and luminescence. The external light source is either an incandescent, fluorescent, LED, (pulsed or continuous wave) monochromatic or dichromatic laser light source. The detector of the photon intensity is either a low light sensing photomultiplier tube (PMT), silicon based photon counting sensor, or Geiger-mode avalanche photodiode detector. The detector of the photon spectrum is a spectrometer. Following exposure to the referenced light sources, fertile avian eggs will exhibit a higher intensity of photons than that of unfertilized avian eggs, and avian eggs of the female gender will emit a different spectrum of photons than will avian eggs of the male gender.

Disclosed are methods and systems for subnanosecond rise time high voltage (HV) electric pulse delivery to biological loads. The system includes an imaging device and monitoring apparatus used for bio-photonic studies of pulse induced intracellular effects. The system further features a custom fabricated microscope slide having micro-machined electrodes. A printed circuit board to interface the pulse generator to the micro-machined glass slide having the cell solution is disclosed. An low-parasitic electronic setup to interface with avalanche transistor-switched pulse generation system is also disclosed. The pc-board and the slide are configured to match the output impedance of the pulse generator which minimizes reflection back into the pulse generator, and minimizes distortion of the pulse shape and pulse parameters. The pc-board further includes a high bandwidth voltage divider for real-time monitoring of pulses delivered to the cell solutions.

A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originate from the light-emitting source, (ii) travel through turbid biological tissue of the subject, and (iii) are emitted from a first surface region of interest of the subject. The light-intensity profile is matched against with a parameter-based biophotonic function, to estimate function parameters such as depth and size. The parameters so determined are refined using data other than the first measured light intensity profile, to obtain an approximate depth and size of the source in the subject. Also disclosed is an apparatus for carrying out the method.

The present technology generally relates to products, devices, methods and systems for healing of wounds or for wound-treatment therapies. More particularly, but not by way of limitation, the present technology relates an absorbent product impregnated with photoactivatable agents, or light-absorbing molecules, as photoactivatable inserts as wound dressing that can be used together as part of negative-pressure wound therapy (NPWT) system or separately and without the NPWT system.

In a biophotonic measurement apparatus using a probe having a plurality of irradiation-detector distances (SD distances) in order to separate light absorption changes in a surface layer and a deep layer of a biological tissue on the basis of near infrared spectroscopy, light reception sensitivity is stabilized on each subject / each region by adjusting an attenuation amount of light to be transmitted or received. It has a light source, a detector for detecting light that has been irradiated from the light source to an irradiation point on the subject and propagated in the subject, a light attenuation amount adjusting means to be disposed on an optical path between the light source—the subject or a photodetector—the subject, an analysis unit for analyzing a signal and a display unit for display a result of analysis, the light source and the detector are respectively arranged such the SD distance defined as a distance between an irradiation point and a detection point is given in two or more kinds, the analysis unit analyzes a measurement signal and calculates a light attenuation adjustment amount for setting respective received light amounts within a predetermined range, and the light attenuation amount adjusting means makes attenuation amounts of light respectively adjustable from the result of analysis by changing an amount of light that is incident upon the detector.

The present invention provides a biophoton spectrum detection system and method. The biophoton spectrum detection system is characterized by adding a sub-photon system composed of slits and a grating on the basis of an ultraweak biophoton imaging system. The grating is an optical element composed of a lot of parallel slits of equal widths and equal intervals, and enables the light to generate chromatic dispersion by utilizing the multi-slit diffraction principle. According to the multi-slit diffraction principle, the ultraweak biophotons emitted out by a to-be-detected sample form a line light source after passing the slits, the line light source irradiates the grating and then is diffracted by the multiple slits to form the bright fringes which are arranged at equal intervals, and the distance is relevant with the wavelength of the biophotons. An imaging subsystem is used for the image recording and analysis. The experiment detection proves that the biophoton spectrum detection system of the present invention is high in sensitivity, can detect the spectrums of the ultraweak luminescence of the biologies, at the same time, has the characteristics of being simple and convenient in operation, good in expansibility and abundant in function, and can be widely used in the fields, such as the life science research, the medical clinical examination, the agriculture production, the food safety, the environment protection, etc.

A device for and a method of measuring a blood flow of a living body having blood vessels that emit bio-photons and through which blood flows, the device including a detector positioned adjacent to a predetermined portion of the living body for measuring a bio-photon emission from the living body and a processor for analyzing and displaying the blood flow of the living body based on a value of the bio-photon emission.

The invention discloses a device for quantitative measurement of symptom in traditional Chinese medicine by use of human bio-photon radiation, which comprises a darkroom, a detector, a front amplifier and a processor. The detector is positioned inside the darkroom, the front amplifier is electrically connected with the detector, the processor is electrically connected with the front amplifier, the detector is used for measuring bio-photons from an acupoint, the front amplifier is used for converting and amplifying the bio-photon signals received by the detector, and the processor is used for recording the intensity of the bio-photons emitted from the acupoint and processing the measurement value. The invention also discloses a method for quantitative measurement of symptom in traditional Chinese medicine by use of human bio-photon radiation, which comprises the following steps: a person enters the darkroom, the detector moves to the position close to a to-be-tested acupoint, a shutter on the detector is opened to measure the bio-photons from the to-be-tested acupoint, and then the processor records the intensity of the bio-photons emitted from the acupoint and processes the measurement value. The invention is rapid, sensitive, reliable, and harmless to human body.

The invention discloses device and method for detecting the property of the traditional Chinese medicine. The device comprises an excitation light source, a sample chamber, a biophoton measuring system and a data processing system, wherein the excitation light source is used for generating excitation light; the light emitted by the exciting light source can be incident into the sample chamber; the biophoton measuring system is used for measuring the intensity of the biophoton emitted by the sample after being excited in the sample chamber; and the data processing system is used for analyzing and processing data measured by the biophoton measuring system which is connected with the data processing system by a circuit. The invention also discloses the method for detecting the property of the traditional Chinese medicine, comprising the following steps of: placing the powdery sample into the sample chamber; exciting the light source to emit the excitation light for irradiating the sample; detecting the intensity of the biophoton emitted by the sample after being excited by using the biophoton measuring system; and transmitting the information data into the data processing system for analyzing, thereby judging the properties of cold, heat and moderate and the degrees of the traditional Chinese medicine of the sample.

The present invention relates to a method for preparation of an ultraviolet (UV)-curable inorganic-organic hybrid resin containing about or less than 4% volatiles and less than 30% organic residues. The UV-curable inorganic-organic hybrid resin obtained according to this method can be UV-cured within a markedly very short time and enables, upon curing, the formation of a transparent shrink-and crack-free glass-like product having high optical quality, high thermal stability and good bonding properties. In view of these properties, this hybrid resin can be used in various applications such as electro-optic, microelectronic, stereolithography and biophotonic applications.

The present disclosure provides thermosetting biophotonic compositions and methods useful in phototherapy. In particular, the thermosetting biophotonic compositions of the present disclosure include block copolymer and at least one chromophore solubilized in the block copolymer. The thermosetting biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.

The present disclosure provides an optical waveguide design of a fiber modified with a thin layer of epsilon-near-zero (ENZ) material. The design results in an excitation of a highly confined waveguide mode in the fiber near the wavelength where permittivity of thin layer approaches zero. Due to the high field confinement within thin layer, the ENZ mode can be characterized by a peak in modal loss of the hybrid waveguide. Results show that such in-fiber excitation of ENZ mode is due to the coupling of the guided fundamental core mode to the thin-film ENZ mode. The phase matching wavelength, where the coupling takes place, varies depending on the refractive index of the constituents. These ENZ nanostructured optical fibers have many potential applications, for example, in ENZ nonlinear and magneto-optics, as in-fiber wavelength-dependent filters, and as subwavelength fluid channel for optical and bio-photonic sensing.

There is provided a portable measuring system having a biophotonic sensor. The portable measuring system also includes a tunable light source, an output intensity detector and an output wavelength detector, which are mounted therein. The portable measuring system can precisely measure a variation in the reflectivity spectrum and / or the transmittance spectrum of the biophotonic sensor before and after an antigen-antibody reaction by varying the wavelength of the tunable light source. Thus, the concentration of the antigen is precisely measured.

The invention provides a high-speed spectral domain optical coherence tomography imaging system based on a Michelson interferometer. The system is characterized by comprising a broadband light source 1, a three-port optical fiber circulator 2, a 1*2 optical fiber coupler 3, a polarization controller 4, a collimating lens 5, a neutral density filter 6, a focusing lens 7, a reflecting mirror 8, a scanning galvanometer 9, a four-dimensional adjusting bracket 10, a tested sample 11, a precise sliding sample platform 12, a transmission-type volume phase holographic diffraction grating 13, an optical fiber collimator 14, a 1*N optical switch 15, an avalanche photodiode detector array 16, a bias voltage control module 17, a signal reading circuit 18 and a signal processing and system control module 19. The system can be used for rapid detection and real-time monitoring of material defects in the industrial field, and can be widely applied to the fields of biophoton medical imaging, cultural relic inspection, industrial measurement, material evidence detection and the like.

The invention discloses a method of imaging by simultaneous compensated focusing of laser beams of multiple wavelengths in a scattering medium. A spatial light modulator is divided into a plurality ofscattering effect compensation subareas; each compensation subarea is further divided into a plurality of wavelength subunits correspondingly according to the quantity of laser beams of different wavelengths to be compensated. Each wavelength subunit correspondingly and independently controls phase compensation of single wavelength; optimal compensation phase distribution on a whole array face ofthe spatial light modulator is formed by sequential arrangement of the wavelength subunit and compensation subarea composite structural modules; phase compensation of single wavelength can be achieved for the subunits of each wavelength according to the incoherence characteristic of wavelength components; when laser beams of multiple wavelengths irradiate the spatial light modulator at the same time, simultaneous compensated focusing imaging of the laser beams of multiple wavelengths in the scattering medium can be achieved. The method has an important application prospect in the fields, suchas laser therapy and biophoton microoperation.

Methods of treating a subject are provided, involving providing a first region of biological material coupled to the subject; initiating a change in a cellular environment of the cells in the first region; and due to a change in biological or chemical activity of the cells in the first region, inducing a biological change in a second region inside the subject, along with various bio-photon collectors and bio-photon bypasses useful for implementing a variety of the method embodiments.

The invention discloses a high precision liquid refractive index sensor based on a sub-wavelength optical grating structure, and belongs to the field of biophoton sensing. The high precision liquid refractive index sensor is composed of a substrate plate, a sub-wavelength optical grating, and a microfluid channel; the sub-wavelength optical grating guided-mode resonance is adopted to realize liquid refractive index high precision measuring. When the liquid refractive index in the microfluid channel is changed, the center wavelength of the transmission spectrum of the optical grating is changed, the center wavelength is firmly related with the value of liquid refractive index. The liquid refractive index can be obtained through measuring the transmission spectrum center wavelength. The highprecision liquid refractive index sensor is a novel sensor used for measuring liquid refractive index, is simple in structure, is convenient to prepare, is high in measuring precision, and is promising in application prospect in the fields of biological sensing, chemical analysis, and medical diagnosis.

The invention provides an application of a generic technology for electric stimulation to increase biomolecular and quantum energy. As a result of difference between an atom and electrons outside of the atom in a biomolecule in quantum level, a ultra-weak biophoton imaging system (UBIS) is applied to detecting. For the biomolecules subjected to direct current or alternating current electric stimulation, electric spark electric stimulation, electromagnetic stimulation of different strength and frequencies or electric stimulation by employing an electron gun which emits electrons, the quantum level of the biomolecule can be improved and radiation of biomolecule-induced biophotons of a brain slice can be obviously enhanced. Experiments detect and verify that the application of a generic technology for electric stimulation to increase biomolecular quantum energy has the characteristics of being simple to operate, reliable, high in efficiency, good in expandability, rich in function and thelike, can be applied to quantum energy increase of various biomolecules, and has application value in life medical research, novel drug research, preparation development, natural and conventional drug modification, quantum biomedical prevention and treatment, chemical industry, agricultural production, functional food and environmental protection and the like.

The invention discloses device and method for detecting the property of the traditional Chinese medicine. The device comprises an excitation light source, a sample chamber, a biophoton measuring system and a data processing system, wherein the excitation light source is used for generating excitation light; the light emitted by the exciting light source can be incident into the sample chamber; the biophoton measuring system is used for measuring the intensity of the biophoton emitted by the sample after being excited in the sample chamber; and the data processing system is used for analyzing and processing data measured by the biophoton measuring system which is connected with the data processing system by a circuit. The invention also discloses the method for detecting the property of the traditional Chinese medicine, comprising the following steps of: placing the powdery sample into the sample chamber; exciting the light source to emit the excitation light for irradiating the sample; detecting the intensity of the biophoton emitted by the sample after being excited by using the biophoton measuring system; and transmitting the information data into the data processing system for analyzing, thereby judging the properties of cold, heat and moderate and the degrees of the traditional Chinese medicine of the sample.

The invention provides application of a generic technology to quantum energy increasing of biomolecules through a photosynthetic reaction. Atoms in the biomolecules, and electrons outside the atoms have the quantum level difference, detecting is carried out through an ultra-weak biophoton imaging system (UBIS), by using a photosynthetic reactor in plant extraction for hatching the biomolecules contained in cytochylema for a certain time under continuous natural or artificial illumination, the quantum level of the biomolecules can be improved, and radiation of brain slice biophoton induced by the biomolecules can be remarkably increased; and through experimental detection, it proves that the application has the advantages of being easy and convenient to operate, reliable, high in efficiency, good in expansibility, rich in function and the like, can be applied to quantum energy increasing of the various biomolecules, and has application value in fields such as life medical science research, new drug development, preparation development, natural and traditional drug modification, quantum biomedicine preventing and treating, the chemical industry, agricultural production, the food andbeverage industry, food and beverage additives, and food safety and environmental protection.

In a biophotonic measurement device based on the principles of near-infrared spectroscopy (NIRS), in order to realize appropriate conditions in any light-source / detector arrangement and various required specifications, a photoirradiation module 13 including a light source 101, a photodetection module 14 including a photodetector 102, and a central control / analysis unit 18 are provided. The central control / analysis unit 18 acquires correspondence relations between each of photodetection units and photoirradiation units by using a correspondence acquiring unit 19. The photoirradiation module 13 and the photodetection module 14 switch signal detection methods at each measurement point by utilizing an evaluation function value determined by detection output of the photodetector 102 so that the plurality of signal detection methods are mixable, and the high-precision and optimum biophotonic measurement device is realized.

The present technology relates to a biophotonic system comprising at least one chromofilm; and a light-emitting support operably connectable to the chromofilm. Operable connection of the light-emitting support and the at least one chromofilm allows for the light-emitting support to illuminate the at least one chromofilm.

The invention provides an application of the technique of reducing the generality of biomolecular molecular energy by utilizing biomolecular interaction. There is a difference in quantum energy level between atoms in biomolecules and electrons outside the atoms. The ultra-weak biophoton imaging system was used for detection, and it was found that the neurotransmitter glutamate interacts with glutamate receptors to achieve quantum energy transfer between molecules. For example, long-term incubation of glutamic acid in artificial cerebrospinal fluid with mouse brain slices can reduce the quantum energy level of glutamic acid, resulting in a significant decrease in its biological effect of inducing ultra-weak biophoton radiation, or even disappear completely. Experimental testing proves that the present invention has the characteristics of simple operation, reliability, high efficiency, and good scalability, and can be applied to the quantum reduction of various biomolecules, and can be used in life medical research, new drug development, preparation development, and improvement of natural and traditional drugs. It has wide application value in the fields of sex, quantum biomedical prevention and treatment, chemical industry, agricultural production, functional food industry and environmental protection.

The invention relates to the technical field of health-care accessories, and discloses a health-care treatment necklace using biophotonic crystals. The health-care treatment necklace comprises a pendant body, wherein a pendant ring is fixedly arranged at the top of the pendant body, a necklace body is fixedly connected to the top of the pendant ring, and fixing grooves are fixedly formed in the two sides of the pendant body. According to the invention, a pendant main stone material or a hollowed-out pendant built-in material is a biophotonic crystal material and can spontaneously generate human body biophotonic waves, so DNA energy is supplemented and enhanced through multi-amplitude interference, and DNA damage is repaired; the pendant body is embedded with a metal ornament for fixation and is connected with a metal necklace in a matched manner, so use convenience and comfort are improved. a first branch necklace body and a second branch necklace body can be freely spliced and assembled between the necklace body and the pendant body, so the attractive effect of the necklace is improved; and meanwhile, the first branch necklace body and the second branch necklace body can be independently taken down and independently used as a bracelet and an anklet, so different use functions are provided, different biophoton radiation positions are provided, and health care effect is improved.

The present disclosure relates to methods for reducing scarring of wounds. The methods comprising topically applying on the wound a biophotonic composition followed by illumination of the applied biophotonic composition with actinic light, wherein the method comprises the following schedule: (a) a period of from about 1 day to about 4 weeks during which, at least once every week the biophotonic composition is topically applied onto the wound and is illuminated for a period of at least 5 minutes, followed by a rest period of less than about a week; and (b) repeating step (a) over a period of at least 4 weeks.

A device for and a method of measuring a blood flow of a living body having blood vessels that emit bio-photons and through which blood flows, the device including a detector positioned adjacent to a predetermined portion of the living body for measuring a bio-photon emission from the living body and a processor for analyzing and displaying the blood flow of the living body based on a value of the bio-photon emission.

The present disclosure provides silicone-based biophotonic compositions and methods useful in phototherapy. In particular, the silicone-based biophotonic compositions of the present disclosure include a silicone phase and a surfactant phase, wherein the surfactant phase comprises at least one chromophore solubilized in a surfactant. The silicone-based biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and scarring, as well as various other skin disorders.

The invention discloses a method for detecting the sensitization of cosmetic ingredients through an ultra-weak biophoton imaging system, which comprises the following steps: S1, pretreatment of materials; S2, tissue block culture; S3, experimental group setting; S4, experimental preparation and Imaging system preheating; S5, positioning and photographing; S6, experimental imaging; S7, sequence image processing and data analysis. The invention uses ultra-weak biophoton imaging technology and immunohistochemical staining method to rapidly detect the changes in the biophoton radiation intensity of the skin tissue donated by the dead body after the culture is treated with DNCB, a common cosmetic sensitizer. The invention can quickly and accurately explore the sensitization of cosmetic ingredients, detect whether the cosmetic contains chemical ingredients that cause skin allergic damage, and has the characteristics of simple and fast operation.

The invention relates to a wheat spontaneous biophoton radiation signal analysis method and apparatus. The method comprises the steps of decomposing an obtained wheat spontaneous biophoton radiation signal by adopting an overall average empirical mode decomposition method to obtain intrinsic mode components of all orders; then processing the intrinsic mode components of all the orders to obtain a group of parameters which represent characteristics of the wheat spontaneous biophoton radiation signal; and according to the parameters, analyzing the frequency domain characteristics of the wheat spontaneous biophoton radiation signal. Compared with a method for performing signal analysis on the wheat spontaneous biophoton radiation signal by adopting a Fourier transform method, the method provided by the invention has the advantages that the limitation is overcome; the energy densities of the wheat spontaneous biophoton radiation signal at different moments and frequencies can be described at the same time; the description of a wheat spontaneous biophoton radiation characteristic is more comprehensive, accurate and real; and the information contained in the signal can be fully mined, so that physiological information of wheat is known more clearly.