355 results about "Ageing skin" patented technology

I have discovered that trace metals such as copper, zinc, iron, and manganese that are necessary for the proper functioning of superoxide dismutase (SOD) and other deactivators of active-oxygen molecules (which cause aging of skin and other skin disorders), can be delivered from the topical compositions. This is achieved by the preparation of copper and other trace metal complexes with phosphorylated nucleosides, such as nucleotides, and phosphorylated monosaccharides, such as phosphorylated glycosides which act as small molecular weight (SMW) transporter molecules. These trace metal complexes of nucleotides and glycosides can be prepared by an in-situ method in water, water-miscible organic solvent, or a mixture of water and water-miscible organic solvent from commonly available ingredients in concentrations that are desirable and can be accurately controlled. I have additionally discovered compositions to achieve the transport of copper from the surface layers of skin into the deeper layers of skin utilizing SMW transporter molecules; and the intra-cellular storage of copper ions in the cell, for example in a bound form with glutathione; and the intra-cellular transport of copper from glutathione to SOD apoprotein by metallochaperones; and the supply of energetic molecules, such as ATP, ADP, or phosphorylated saccharides for SOD metallochaperones to perform their intra-cellular metal transfer function. These cosmetic or pharmaceutical compositions are useful for antiaging and antiviral benefits.

The invention belongs to the technical field of skin care oil medicine, in particular to skin care oil medicine containing peony oil and a preparation method thereof. The skin care oil medicine provided by the invention comprises the following components in parts by weight: main ingredients: peony seed oil, caprylic / capric triglyceride, cyclopentasiloxane and 1, 2 - butyl glycol 1-12, wherein the peony oil is peony seed oil or peony essence oil or the mixture of peony seed oil and peony essence oil; auxiliary ingredients: isostearic acid, butylated hydroxytoluene, avocado oil, simmondsia chinensis seed oil, meadowfoam seed oil and macadamia ternifolia seed oil; the skin care oil medicine containing peony oil prepared by the method provided by the invention can remarkably improve of the skin epidermis cell cycle function, promote the microcirculation of the blood capillary of the dermal skin effect, inhibit lipid peroxidation, improve metabolism, delay skin aging process, is provided with anti-wrinkle, moisturizing and whiting effect, people feels smooth and comfortable after the skin care oil medicine is used on the skin, and the skin care oil medicine containing peony oil is provided with better effect to chloasma, aging skin wrinkles, skin cutin hardening peeling and skin chap.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, muscular dystrophies, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

The invention discloses a compound with a wrinkle removing function. The compound comprises triterpenoid saponin and triterpene acid, wherein the triterpenoid saponin and the triterpene acid are active ingredients from centella. The triterpenoid saponin comprises one or two of asiaticoside and hydroxy asiaticoside, and the triterpene acid comprises one or two of asiatic acid and madasiatic acid. By compounding any one or two of the triterpenoid saponin with any one or two of the triterpene acid, human skin fibroblast secretes type I collagen, and the like can be remarkably improved, the obvious effect of aging skin regeneration is realized, and the compound can be used for the development of wrinkle removing cosmetics.

A pharmaceutical composition for treatment of skin aging including a pharmaceutically effective amount of estriol; a pharmaceutically effective amount of estradiol; a pharmaceutically effective amount of hyaluronic acid; a pharmaceutically effective amount of green tea extract; and a pharmaceutically acceptable carrier is provided. In some embodiments, the composition further includes ascorbic acid, date palm extract, or a combination thereof. Also disclosed is a method for treating symptoms of skin aging and photoaging by administering a pharmaceutical composition having estriol, estradiol, hyaluronic acid, green tea extract, a pharmaceutically acceptable carrier and optionally, ascorbic acid and date palm extract. A method of promoting urogenital function is likewise provided wherein a pharmaceutical composition having estriol, estradiol, hyaluronic acid, and green tea extract is applied intravaginally.