50results about How to "Increase skin hydration" patented technology

Transcutaneous immunization can deliver antigen to the immune system through the stratum corneum without physical or chemical penetration to the dermis layer of the skin. This delivery system induces an antigen-specific immune response. Use of skin-active adjuvants is preferred. Although perforation of intact skin is not required, superficial penetration or micropenetration of the skin can act as an enhancer; similarly, hydration may enhance the immune response. This system can induce antigen-specific immune effectors after epicutaneous application of a formulation containing one or more antigen and adjuvant. The formulation may initiate processes such as antigen uptake, processing, and presentation; Langerhans cell activation, migration from the skin to other immune organs, and differentiation to mature dendritic cells; contacting antigen with lymphocytes bearing cognate antigen receptors on the cell surface and their stimulation; and combinations thereof. Systemic and/or regional immunity may be induced; immune responses that result in prophylaxis and/or therapeutic treatments are preferred. Antigen and adjuvant activities in the formulation may be found in the same molecule, two or more different molecules dissociated from each other, or multiple molecules in a complex formed by covalent or non-covalent bonds. For antigens and adjuvants which are proteinaceous, they may be provided in the formulation as a polynucleotide for transcutaneous genetic immunization. Besides simple application of a liquid formulation, patches or other medical devices may be used to deliver antigen for immunization.

This invention provides compositions and methods of manufacturing such compositions that employ GRAS compounds which can act to promote the generation of stem, epidermal or other skin cells in the epidermis, activation of collagen synthesis, activation of hyaluronic acid synthesis, enhanced skin hydration, and dermal healing by stimulating stem cell and fibroblast migration to sites of needed repair. These compositions and methods are useful for rejuvenating the skin and for treating some skin-related aging or other dermal damaging conditions, including wrinkle reduction and treatment of minor dermal wounds.

An improved composition for treatment of the skin comprises: (1) methionine and cysteine in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (2) a mixture of essential amino acids in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin, the mixture comprising isoleucine, leucine, lysine, phenylalanine, threonine, tryptophan, valine, histidine, and arginine; (3) at least one antioxidant in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (4) at least one cross-linking agent in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (5) at least one metallic catalyst in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (6) at least one transepidermal delivery agent in a quantity sufficient to promote delivery of the composition to the skin; and (7) a topical pharmaceutically acceptable carrier. The antioxidant can be ascorbic acid. The cross-linking agent can be proanthocyanidin or silybin. The metallic catalyst can be Cu (II) in a suitable cupric salt. The transepidermal delivery agent can be benzyl alcohol.

Compositions, devices and methods for improving the aesthetic appearance of skin are described. In one embodiment, the compositions, devices and methods reduce fine lines and/or wrinkles, and in other embodiment, the compositions, devices and methods improve skin tone by reducing regions of hyperpigmentation. The cosmetic compositions and devices described are formulated for topical application for extended wear, and comprise one or more agents to achieve the desired beneficial effect. The composition is preferably an adhesive composition that is secured to the skin for an extended time for sustained release of the one or more beneficial agents.

The present invention relates generally to methods of use and compositions useful for treating skin. The composition includes a combination of one or more of Butyrospermum parkii (shea butter), PEG-50 shea butter, glycerin, Helianthus annuus (sunflower) seed oil, Prunus armeniaca (apricot) kernel oil, acrylates copolymer, sodium lauryl sulfate, lauramidopropyl betaine, sodium methyl cocoyl taurate, glycerin, and polyquaternium-7.

Electrolytic acid or alkaline water having a NMR half line width using 17O of from about 45 to less than 51 Hz, and an oxide reduction potential of from −1000 to +200 mV, or from +600 to +1300 mV, topical compositions that contain such water, uses for such water to hydrate skin, deliver drugs and treat various skin and mucosal conditions, and methods and apparatus for manufacturing the water.

A sprayable film-forming pharmaceutical composition for dermal application comprises at least one therapeutically active ingredient dissolved in a pharmaceutically acceptable propellant selected from the group consisting of dimethyl ether, diethyl ether and methylethylether, and a mixture of dimethyl ether, diethylether and methylethyl ether, and a second propellant selected from C_3-5 alkanes, hydrofluoroalkanes, hydrochloroalkanes, fluoroalkanes and chlorofluoroalkanes, the propellant being present in an amount of 50-99.5% w/w of the composition, the composition further comprising a film-forming polymer, a plasticizer and an oily release-enhancing agent.

The invention relates to a liquid skin-cleansing composition. The liquid skin-cleansing composition is prepared from the following raw materials in parts by weight: 3.0-15.0 parts of natural grease, 18.0-27.0 parts of fatty acid, 6.0-8.0 parts of potassium hydroxide, 0.2-3.0 parts of a non-ionic surfactant, 0.1-3.0 parts of brown sugar, 1.0-5.0 parts of potassium cocoyl hydrolyzed avenin, and 50.0-60.0 parts of water; and the non-ionic surfactant is a composition of PEG/PPG-80/20 copolymers, PEG-32 and PEG-6. The liquid skin-cleansing composition is low in viscosity and is conveniently taken for use, and the liquid skin-cleansing composition is added into cleaning products and is easy to rinse, the dry and tight body feeling is avoided, rich foam can be formed, and the foam amount of the liquid skin-cleansing composition is not affected even if the liquid skin-cleansing composition is used in hard water.

The present invention provides a method of enhancing hyaluronic acid secretion in a subject, which comprises administrating a composition containing of Streptococcus thermophilus DSM 28121 to the subject, and the hyaluronic acid content in the blood of the subject is increased. The present invention further provides a novel probiotic strain which is Streptococcus thermophilus DSM 28121, which has the ability to survive and colonize in the intestine of the subject to increase the number.

A compound of formula (I) R₁-W_m-X_n-AA₁-AA₂-AA₃-AA₄-AA₅-AA₆-AA₇-AA₈-AA₉-Y_p-Z_q-R₂, wherein AA₁ is Phe; AA₂ is Trp; AA₃ is selected from Met, Leu and Ile; AA₄ is selected from Lys, Arg and Gln; AA₅ is Arg; AA₆ is Lys; AA₇ is selected from Arg, Lys and His; AA₈ is selected from Val, Ile, Leu and Met; and AA₉ is Pro. The compound is useful in the treatment and/or care of the skin, hair, nails and/or mucous membranes, in particular for improving the barrier function of the skin, for energizing the skin and as an anti-aging agent.

This invention relates to benzoyl peroxide products for skin treatment, and more particularly to a kit containing a benzoyl peroxide product and a topical moisturizing product. In one embodiment the kit contains BenzaClin® brand clindamycin-benzoyl peroxide gel and Viscontour® brand hyaluronic acid serum.