114results about How to "Enhance skin barrier function" patented technology

A composition suitable for topical application comprising a continuous phase and at least one discontinuous phase, said composition comprising at least one polyaphron dispersion, at least one vitamin D or vitamin D analogue and at least one corticosteroid.

Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates such as feces and menses. The skin care formulation comprises a film forming agent that, upon transfer to the skin, can form a continuous film layer on the skin to retard harmful agents.

The invention relates to a moisturizing composition, and a preparation method and application thereof, which belong to the field of cosmetics. The moisturizing composition is prepared from the following components in parts by weight: 1.0 to 5.0 parts of sodium hyaluronate, 2.0 to 10.0 parts of carboxymethyl deacetyl chitosan, 30.0 to 60.0 parts of dendrobium officinale extract, and 25.0 to 67.0 parts of deionized water. The moisturizing composition can well form a netted natural biomimetic membrane with skin, the sodium hyaluronate performs the water supplementation and moisturizing in the biomimetic membrane, the carboxymethyl deacetyl chitosan forms a biomimetic sterile membrane, so that natural moisturizing factors such as the sodium hyaluronate can be effectively locked, the water loss rate is decreased; and the dendrobium officinale polysaccharide is combined with the natural biomimetic sterile membrane, so that the moisturizing lasting property after long-term use can be further improved, the restoration effect is improved, and the dryness and allergy problems of the skin can be fundamentally solved. The moisturizing composition has multidimensional efficacy such as moisturizing function, restoration function and skin barrier increasing function.

Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates such as feces and menses. The skin care formulation comprises a film forming agent that, upon transfer to the skin, can form a continuous film layer on the skin to retard harmful agents.

A breast pad assembly is disclosed wherein one face of the breast pad which faces the breast during use contains a composition comprising a skin benefit ingredient for improving the skin health of a woman's breast and nipple skin. In one embodiment of the invention, the skin health benefit ingredient comprises omega-3 fatty acids which can replace lipids lost from the breast and nipple during breast feeding. The omega-3 fatty acids can also be ingested by the infant to improve systemic development in the infant. In another embodiment, the skin benefit ingredient comprises omega-3 fatty acids and essential fatty acids.

The invention relates to a skin barrier function-improving agent that comprising, as an active ingredient, an inositol derivative containing an inositol and a saccharide bonded together, and a composition for improving skin barrier function that comprises the skin barrier function-improving agent and a pharmaceutically acceptable carrier.

The invention discloses a restoring serum and a preparing method thereof, and is aimed at providing the serum which can effectively improve the skin permeability, balance the water storage, improve the skin shielding function and relieve and resist inflammation. The restoring serum is technologically characterized by comprising glycerinum or butanediol, erythritol or trehalose, sodium hyaluronate,a natural plant restoring factor, rona care ectoin, a water / / butanediol / / amino acid compound, a water / / lactobacillus / soybean fermentation product extract / / butanediol and other components. The invention belongs to the technical field of cosmetics.

The invention provides infant cream and a preparation method thereof, and belongs to the field of skincare products. The infant cream comprises the following raw materials in percentage by weight: 0.05-5% of an emulsifier, 0.1-5% of solid grease, 5-15% of liquid grease, 5-20% of a moisturizing agent, 0.01-2% of a rheolobic modifier, 0.01-1% of ceramide, 0.1-3% of other active components, 0.01-1% of a preservative and the balance of deionized water. The infant cream provided by the invention aims at the skin characteristics of infants and infantile eczema, ceramide is compounded with other active components, and an infant skincare product which has the characteristics of high security, skincare functions and wound skin repairing can be prepared. The cream is fine and smooth in skin feeling,excellent in moisturizing, allergy prevention and grease replenishing property and capable of improving the capability of preventing external irritation and improving self repairing of infant skin. In addition, the infant cream provided by the invention is uniform in particle size and good in stability.

The invention relates to a triad integration freckle-removing functional nano cream for skin external use and a method for preparing the same. The three types (night use type, daytime use type and auxiliary type) freckle-removing nano creams improve and optimize a novel international passive target transdermal drug delivery system (TDDS) as a carrier, and organically combine and solubilize freckle-removing functional components with different biological efficacies, action ways and physical and chemical properties to form a good mutual aid synergic function system which has remarkable effect of controlling and relieving colored patches (such as chloasma, inflammatory pigmentation, sunburn, and the like) caused by abnormal facial metabolism of pigment. The product has the advantages of tiny particle sizes of spherical particles, obvious passive target function, excellent adaptability, homodromous property, fluidity and dispersion, strong penetrability, even texture, subtleness, lubricity and luster, is simple and convenient to use, and is comfortable without pungency and side effects; besides, the appearance is light yellow with slight opalescence, is glittering and translucent, clear and transparent, sticky but not viscous, thick but not dense, and oily but not greasy, has good stability, excellent curative effect, short industrialization cycle and high production efficiency, saves time, materials and energy sources, dose not need special devices and heat energy, and is easy for popularization and application.

The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.

The invention provides moisturizing cream and a preparation method thereof. The moisturizing cream comprises: by mass, 5-40%, preferably 10-25%, more preferably 15-35%, of a grease; 2.1-20%, preferably 2.5-10%, more preferably 3-8%, of an emulsifier; 1-40%, preferably 5-30%, more preferably 10-25%, of a humectant; 0-2%, preferably 0.1-2%, more preferably 0.1-1%, of a thickener; 1-10%, preferably 2-10%, more preferably 5-10%, of a skin conditioner. The emulsifier is a composite emulsifier composed of polyglyceryl-6 stearate, jojoba esters, polyglyceryl-3 beeswax, and cetyl alcohol. The moisturizing cream can form a constantly moisturizing protective film with better moisturizing degree on the skin surface, which is a bionic skin sebum film.

The invention belongs to the field of cosmetics, relates to an anti-sensitive product and in particular to a skin-soothing anti-sensitive essence. The essence comprises a plant extract including the following extracts in optimal ratio: 1 part of cortex dictamni extract, 1 part of tamarix chinensis flower / leaf extract, 1 part of brasenia schreberi leaf extract, 1 part of fructus kochiae extract, 2 parts of benincasa hispida extract, 1 part of radix coptis chinensis extract, 2 parts of radix scutellaria baicalensis extract, 2 parts of radix sciadopitys verticillata extract, 1 part of pelvetia canaliculata extract, 1 part of taraxacum mongolicum extract, 1 part of honeysuckle flower extract and 1 part of clematis vitalba leaf extract. The essence also comprises the components in the ratio of 1%-10% of glyceryl polyacrylate, 1%-5% of nicotinamide, 1%-10% of glucan, 1%-5% of palmitoyl tripeptide-8, 1%-10% of glycerine, 1%-10% of butanediol, 1%-5% of sodium hyaluronate, 1%-5% of silver oxide, 45%-65% of plant extract and the balance of deionized water. The essence has multiple effects of antagonizing external stimulation, inhibiting sensitivity, diminishing inflammation, relieving itching, whitening, moisturizing, moistening and repairing.

The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.

The invention provides a compound for repairing damaged skin. The compound comprises the following components by weight percent: 35%-45% of sodium hyaluronate hydrolysate, 25%-30% of sodium hyaluronate, 20%-30% of centella extract and 20% of compound amino acid. The compound provided by the invention is capable of solving the problems that few products with repairing and soothing effects exist inthe cosmetics market at present and active substances are difficult to be absorbed and fully utilized; the compound can be added into common cosmetic preparations, such as water, essence, emulsion andcream, and can exist stably; the repairing and soothing effects are excellent.

A wipe article comprising a lotion composition comprising omega-6 fatty acid. A method of improving skin barrier function of vulvar skin comprising the step of contacting the vulvar skin with a wipe article, wherein omega-6 fatty acid is disposed on the surface of the wipe article.

The subject invention provides compositions and methods for treating human dermatological conditions by employing a microbiome-centered treatment approach. Preferred embodiments of the invention provide pharmaceutical and cosmetic compositions, and the methods of using the same, comprising a strain of Lactobacillus fermentum bacterium, or bioactive extracts thereof, derived from human microbiota and capable of growing in biofilm phenotype.

The present invention provides a low-toxicity sophorolipid-containing composition. The low-toxicity sophorolipid-containing composition contains at least a coloring component, an acidic sophorolipid, a fatty acid, and a hydroxy fatty acid that are derived from an SL-producing yeast culture. The composition contains the following components in the following proportions, in terms of dry weight, based on the total amount of the acidic sophorolipid, a lactonic sophorolipid, the fatty acid, and the hydroxy fatty acid in the composition taken as 100 mass %:(1) acidic sophorolipid: 94 to 99.99 mass %,(2) lactonic sophorolipid: 0 to 2 mass %,(3) total amount of fatty acid and hydroxy fatty acid: 0.01 to 4 mass %

Disclosed is a combination for skin external use, which contains as an active ingredient an herbal extract complex consisting of Chinese herbal extracts of Granate bark, seed of Prunus armeniaca, Coix lacuma-jobi, Saururus chinensis and Perilla frutescens var. acuta. More particularly, disclosed is a composition for skin external use containing an herbal extract complex, which is prepared by mixing the Chinese herbs with each other at an optimal ratio to prepare an herbal mixture and extracting the herbal mixture to prepare an herbal extract complex, and thus shows the effects of promoting the differentiation of skin keratinocytes, restoring impaired skin barrier function and increasing skin moisturization compared to extracts obtained by extracting each of the herbs alone.

The invention belongs to the technical field of processing of skin care products and particularly relates to a roxburgh rose skin-brightening bio-cellulose mask. The bio-cellulose mask comprises a bio-cellulose film material, a roxburgh rose extracting solution and rose flower water. According to the special extraction process and preparation method, the prepared mask is excellent in biocompatibility, high in water retaining property and excellent in wet flexibility, and has the effects of softening epidermal keratin and promoting the keratin to peel, inhibiting microbe growth in hair follicles, eliminating oxygen free radicals, stimulating cell growth and division, reducing fine lines, reducing wrinkles and brightening the skin.

The invention relates to the field of medical treatment, in particular to a novel mask capable of maintaining beauty and keeping young and a medicine, and a preparation method thereof. A raw materialcomponent A comprises hot spring water, butylene glycol, glycerin, xanthan gum, hydroxyethyl cellulose, sodium hyaluronate, and disodium EDTA; a raw material component B comprises capryloyl hydroxamicacid, 1,2-hexanediol, propylene glycol, allantoin, and PEG-40 hydrogenated castor oil; and a raw material component C comprises a rose flower extract, a Dendrobium candidum extract, nicotinamide, sorbitol, glycine betaine, acrylic acid / MA copolymer sodium, caprylyl glycol, dipotassium glycyrrhizinate, a centella extract, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, and palmitoyl tripeptide-1. The raw material component A is added to a homogenous pot, the material is stirred and heated to 70-80 DEG C, insulation is carried out for 20-30 minutes; the cooling water is used for cooling; when the temperature drops to 50 to 70 DEG C, the raw material component B is added, and stirred and cooled.

Disclosed is a composition containing phosphatidylserine as an effective ingredient, and more particularly to a composition containing phosphatidylserine as an effective ingredient for protecting and improving a skin, reinforcing a skin barrier function, suppressing and alleviating an inflammatory response, treating and improving an atopic skin, activating PPAR-a promoting a differentiation of the skin, protecting the skin and preventing and improving skin aging and wrinkle. Accordingly, it is possible to protect and improve the skin from the injury due to the ultraviolet or the external stimulating material such as chemical material and to reinforce and strengthen the skin barrier function using the composition, thereby improving a general skin state.

The invention discloses moisturizing, skin brightening and repairing essence containing yeast rice fermentation product filtrate and a preparation method of the moisturizing, skin brightening and repairing essence, and aims to provide essence which is easy to absorb, can improve water shortage, dark and dry skin, does not block pores, does not cause secondary damage to the skin and has moisturizing, skin brightening and repairing effects. The technical scheme comprises the following components in percentage by weight: 1.0-20.0% of yeast / rice fermentation product filtrate, 0.01-0.3% of poly gamma-sodium glutamate, 0.02-0.1% of tremella polysaccharide, 0.1-1.0% of lactobacillus plantarum fermentation rice, 0.05-0.3% of CeracareT45, 0.1-1.0% of a skin brightening agent, 0.1-3.0% of a composite fullerene stock solution, 0.3-3.0% of an ion humectant, 1.0-5.0% of propan-1,3-diol, 0.05-0.5% of a chondrus crispus extract, 0.1-0.5% of diisostearyl malate, 0.05-0.3% of sodium hyaluronate oligosaccharide, 1.0-5.0% of a yeast fermentation product filtrate mixture, 0.05-0.3% of beta-glucan, 0.2-1.0%of phytosphingosine, and the balance of the deionized water, wherein all of the raw materials is100%. The invention belongs to the technical field of cosmetics.

The subject invention provides compositions and methods for treating human dermatological conditions by employing a microbiome-centered treatment approach. Preferred embodiments of the invention provide pharmaceutical and cosmetic compositions, and the methods of using the same, comprising a strain of Lactobacillus fermentum bacterium, or bioactive extracts thereof, derived from human microbiota and capable of growing in biofilm phenotype.

The invention discloses a skin repair composition and application thereof in cosmetics. The composition is prepared from, by weight, 5-20% of a welwitschia seed stem cell preparation, 0.5-2.0% of a freeze-dried biological amniotic membrane, 0.2-1.0% of curcumin, 0.25-1.00% of sodium hyaluronate, 3-15% of polyol, 0.1-5.0% of a humectant, 0.45-0.75% of a natural plant preservative, 0.02-0.08% of disodium ethylene diamine tetraacetate and the balance deionized water. According to a formula, the welwitschia seed stem cell preparation, the freeze-dried biological amniotic membrane and the sodium hyaluronate are used for synergistically accelerating cell proliferation and promoting repair of the skin barrier of the skin damaged by hormones, and the curcumin cleans away excessive free radicals ina biochemical reaction process so as to avoid more damage to the cells. The skin barrier function is improved while the hormonal face is repaired.

The invention provides an anti-allergic composition which mainly comprises the following components by weight: 30%-70% of a cactus extract, 10%-50% of saccharide isomerate and 8%-40% of polyquaternium-51. The cactus extract capable of effectively inhibiting activity of hyaluronidase, polyquaternium-51 and saccharide isomerate with a barrier function complement each other; polyquaternium-51 havinga film forming effect for capturing irritant substances and the saccharide isomerate capable of restoring the barrier function of the skin together help to achieve a better anti-allergic effect and enhance the barrier function of the skin. The invention further provides a cosmetic containing the anti-allergic composition, wherein the anti-allergic composition accounts for 1.0%-10% of total weightof the cosmetic. A mouse auricle anti-inflammatory test and a hyaluronidase in-vitro inhibitory test prove that the cosmetic containing the anti-allergic composition provided by the invention not onlyhas an excellent anti-inflammatory effect, but also has a strong inhibition rate for activity of hyaluronic acid and improves the barrier function of the skin.

The invention relates to the field of daily chemical, in particular to a preparation method of a rosa canina fruit extract and application thereof in a skin care cream. The preparation method mainly comprises the steps that 1, dried rosa canina fruits are subjected to superfine grinding so as to pass through a 100-mesh sieve; 2, a composite biological enzyme is prepared; 3, the ground rosa canina fruits are added into a solvent, then the temperature is increased to 50-55 DEG C, then the composite biological enzyme is added, the pH is adjusted by acid to be 4.5-5.0, after the mixture is stirred to be uniform, enzymolysis is kept for 2 H at the temperature of 50-55 DEG C, then the temperature is rapidly increased to 100 DEG C for rapid inactivation, the temperature is decreased to 80 DEG C 1 MIN after inactivation, and reflux extraction is carried out for 1H; 4, the extract is filtered, deslagged, concentrated and dried to obtain an educt. The method has the advantages of being high in catalysis efficiency, mild in catalysis condition, and capable of lowering energy consumption, reducing pollution and simplifying technological procedures. When the rosa canina fruit extract prepared through the preparation method is applied to the skin care cream, the effects of well moistening, moisturizing and repairing skin can be achieved.

A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and / or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.

Disclosed are a composition for protecting skin and uses thereof. The composition comprises sphingomyelin as an active ingredient and protects the skin by inhibiting skin aging, treating a skin wound and improving a skin barrier.

The invention provides a ceramide-containing grease composition, the grease is selected from vegetable grease, animal grease or a combination thereof, the vegetable grease is selected from shea butter, olive oil, safflower seed oil, meadowfoam seed oil, plant squalane or a combination thereof, the animal grease is deep sea fish oil, and the ceramide-containing grease composition is prepared from ceramide. Based on the total weight of the composition, the composition comprises 0.01 to 5 weight percent of ceramide. The invention also relates to an application of the grease composition containing ceramide in enhancing the skin barrier function and / or in preparing a medicine for enhancing the skin barrier function and / or an external preparation for the skin.