The invention discloses a deformation wheel with a pulley and steel cable connection structure, which mainly comprises a wheel hub, a moving wheel rim unit and a telescopic wheel spoke unit, wherein the moving wheel rim unit comprises an arc-shaped inner frame and an arc-shaped outer frame, the moving wheel rim unit forms a wheel rim structure through a serial connection mode of head to tail; thetelescopic spoke unit comprises a fixed frame, a sliding sleeve and a tension spring, wherein two ends of the tension spring are provided with circular rings, the tension spring is sleeved with the sliding sleeve, a rail wheel of the sliding sleeve is clamped on the inner frame of the fixed frame, one ends of the tension spring and sliding sleeve are clamped in the arc-shaped outer frame, the fixed frame is clamped in a clamping groove of the wheel hub through a clamping plate; four corners of the fixed frame are provided with four pulleys, two pulleys, the circular rings and the rail wheel are connected in series through an outer steel cable, and the other two pulleys are connected in series with a fixed point of the steel cable on the sliding sleeve by an inner steel cable. According tothe invention, the deformation wheel which is deformable in the circumferential direction and the radial direction is constructed, the deformation flexibility is high, the deformation recovery capability is strong, the deformation wheel can adapt to various landforms such as upstairs and downstairs, obstacle crossing and the like, and the deformation wheel is suitable for wide popularization and use.