Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
55results about How to "Reduce the effective dose" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Nano emulsion injection of alprostadil and preparation method
InactiveCN1872072AImprove solubilityImprove stabilityOrganic active ingredientsEmulsion deliveryIsoprostaglandin E1Curative effect
A nano-emulsion injection of prostaglandin E1 contains the nano-emulsion particles of rostaglandin E1, the oil for injection, hydrophilic emulsifier, lipophilic emulsifier, isotonic agent, and stabilizer. Its preparing process and its quality control method are also disclosed.
Owner:广州中大创新药物研究与开发中心有限公司
Pharmaceutical composition and application thereof to preparation of medicament for treating cerebrovascular disease
InactiveCN102485223AReduce the effective doseGood treatment effectHydroxy compound active ingredientsCardiovascular disorderDiseaseVascular disease
A pharmaceutical composition comprises 3-methyl-1-phenyl-2-pyrazoline-5-ketone and (+)-2-borneol. The pharmaceutical composition can be used in treating cerebrovascular disease and has lower toxic and side effects.
Owner:JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
A pharmaceutical composition and the application thereof in the preparation of medicine for the treatment of cerebrovascular diseases
ActiveCN101848711BReduce the effective doseGood treatment effectOrganic chemistryHydroxy compound active ingredientsDiseasePharmaceutical drug
Owner:NANJING SIMCERE DONGYUAN PHARM CO LTD +1
A pharmaceutical composition comprising butylphthalide and borneol and applications thereof
InactiveCN104224772AGood treatment effectReduce the effective doseHydroxy compound active ingredientsCardiovascular disorderDiseasePharmaceutical drug
A pharmaceutical composition comprising butylphthalide and borneol is disclosed. The pharmaceutical composition has synergistic effects on treating cerebrovascular diseases especially ischemic cerebrovascular diseases, and is capable of obviously enhancing treating effects of the butylphthalide, reducing the effective dose of the butylphthalide, and reducing the using amount. Untoward effects of the pharmaceutical composition during long-term application can be reduced.
Owner:CSPC ZHONGQI PHARM TECH (SHIJIAZHUANG) CO LTD
Chlorantraniliprole-emamectin benzoate suspending agent and preparation method thereof
InactiveCN103651419AMeet the requirements for the development of green and environmentally friendly pesticidesMeet development requirementsBiocideAnimal repellantsBenzoic acidAbamectin
The invention discloses a chlorantraniliprole-emamectin benzoate suspending agent and a preparation method thereof. The chlorantraniliprole-emamectin benzoate suspending agent is mainly used for preventing and treating insect pests on crops. The effective components of the composition comprise 1-20% of chlorantraniliprole, 1-10% of emamectin benzoate, 3-6% of a dispersant, 0.5-3% of a lubricant, 0.1-1% of a stabilizer, 0.05-0.2% of a defoamer, 0.2-5% of a suspending agent, 3-5% of an antifreezing agent and the balance of water. The insecticidal compound suspending agent is a green and environment-friendly pesticide which is free from three wastes in production and convenient to use.
Owner:QINGDAO STAR CROPSCI
Medical application of pregabalin
InactiveCN103385870AExact therapeutic effectGood treatment effectOrganic active ingredientsCardiovascular disorderDiseaseGabapentin
The invention relates to an application of pregabalin in preparing a drug for treating and preventing ischemic cerebrovascular diseases, and belongs to the medicine field. Pregabalin is a conventional drug. According to the invention, a great many of experiments demonstrate that pregabalin can reduce NO and NOS level of an ischemic patient when the pregabalin is applied in the treatment of ischemic cerebrovascular diseases particularly cerebral ischemia or cerebral infarction, can reduce MDA content in serum, and has an obvious protect effect for brain hippocampus neurons. The medical application of gabapentin can provide a novel drug selection of patients suffering from the ischemic cerebrovascular diseases, and has wide medical application prospects.
Owner:LUNAN PHARMA GROUP CORPORATION
Suspending agent containing chlorantraniliprole and lambda-cyhalothrin and preparation method thereof
InactiveCN103651521AThixotropicWith colloidal propertiesBiocideArthropodicidesOrganic solventInsect pest
The invention discloses a suspending agent containing chlorantraniliprole and lambda-cyhalothrin. The suspending agent is mainly applied to control of insect pests on crops. The lambda-cyhalothrin is low in melting point, so that dosage form of the lambda-cyhalothrin at present is mainly emulsified after being dissolved, and is mainly missible oil, a microemulsion and an emulsion in water, but the three dosage forms contain benzene organic solvents, and are not environmental dosage forms in true sense. By adopting the suspending agent, the complex suspending agent of the chlorantraniliprole and the lambda-cyhalothrin is introduced, does not contain an organic solvent, does not contain carcinogenic, teratogenic or mutagenic agents, and is the environmental dosage form in true sense. The composition comprises the main effective components of 1-20% of chlorantraniliprole, 1-10% of lambda-cyhalothrin, 3-6% of dispersing agent, 1-2% of wetting agent, 1-2% of stabilizer, 0.1-0.2% of defoamer, 0.2-5% of suspending agent, 3-5% of antifreezing agent and the balance of water. The insecticidal compound suspending agent belongs to an environment-friendly pesticide, is free of three wastes in production, and is convenient to use.
Owner:QINGDAO STAR CROPSCI
New application of clausena lansium leaves
InactiveCN105012452AInhibits α-glucosidase activityReduce the effective doseMetabolism disorderFood preparationMedicinal herbsClinical efficacy
The invention relates to application of clausena lansium leaves to preparation of alpha-glucosidase inhibitor products. The clausena lansium leaves are dried leaves of a rue family clausena plant clausena lansium (Lour.) Skeels. The invention further provides a composition with an alpha-glucosidase activity inhibiting effect. The composition comprises a clausena lansium leaf raw medicinal material or medicinal slices or extract of the material and other traditional Chinese medicinal materials such as coptis chinensis, panax ginseng and safflower carthamus. The composition or a preparation of the composition can be used for inhibiting the alpha-glucosidase activity, and reducing or assisting in reducing postprandial blood sugar or preventing and / or treating obesity clinically. The composition can be used as health-care food or food, and is high in safety. The preparation method is simple, and the product with the clinical effect can be obtained by adopting a conventional extraction and separation technology.
Owner:周亚伟
Flusilazole-containing aqueous emulsion
The invention relates to an agricultural preparation, in particular to a flusilazole-containing aqueous emulsion which consists of 2 percent to 30 percent of flusilazole, 5 percent to 20 percent of solvent, 5 percent to 15 percent of surfactant, 1 percent to 6 percent of antifreeze and the balance of the water. The bactericidal aqueous emulsion pertains to an environment-friendly bactericide, performs protective and therapeutic treatment actions, and especially has good effects in protecting and treating apple scab, apple powdery mildew and the like.
Owner:北京绿色农华作物科技有限公司
Insect-resistant agent for flower planting and preparation method thereof
InactiveCN107006543AGood control effectLong durationBiocideDead animal preservationHuman healthAllium sativum
The invention discloses an insect-resistant agent for flower planting. The insect-resistant agent comprises the following raw materials in parts by weight: 10-20 parts of garlic, 8-13 parts of azedarach, 3-7 parts of saponin, 5-15 parts of clove, 1-10 parts of folium artemisiae argyi, 2-3 parts of plant ash, 3-5 parts of nano-silver, 1-4 parts of attapulgite clay, 3-6 parts of additives, 3-8 parts of ramie seed oil and 30-50 parts of deionized water. The insect-resistant agent for flower planting, disclosed by the invention, is excellent in control effect, long in lasting period, green, pollution-free and harmless to human health and difficultly produces drug resistance.
Owner:ANHUI MEILAN LANDSCAPE ENG CO LTD
Preparation method of endogenous interferon inducer injection and nanometer microencapsulation solution
InactiveCN101810638AAvoid species-specific defectsEffectively control viral infectionsOrganic active ingredientsAntiviralsDrug administrationAnimal body
The invention discloses a preparation method of endogenous interferon inducer injection and nanometer microencapsulation solution, relating to a pharmaceutical composition for treating and curing breeding animal viral infection by improving the inducement level of endogenous interferon. The invention uses endogenous interferon induction technology, avoids the defects of strong specificity of self species of interferon preparation, is convenient to apply in production and practice by drug administration in various modes and has the characteristics of low onset dose and the like, and degradation products can directly enter an animal body metabolic pool to continue metabolizing. In addition, the invention has an important meaning for effectively controlling raised animal viral infection and lowering drug residue harm.
Owner:QINGDAO AGRI UNIV
Pharmaceutical composition and application of same in preparation of medicines used for treating cerebrovascular diseases
ActiveCN103070861AImprove the effect of treatmentReduce the effective doseHydroxy compound active ingredientsCardiovascular disorderSodium AcrylateDrug
The invention relates to the field of medicine and discloses a pharmaceutical composition and application of the same in preparation of medicines used for treating cerebrovascular diseases. The pharmaceutical composition comprises trans-3-[4-(1H-imidazole-1-ylmethyl)phenyl]-2-sodium acrylate and 2-borneol.
Owner:NANJING SIMCERE DONGYUAN PHARM CO LTD +1
Pharmaceutical composition containing butyphthalide as well as application of pharmaceutical composition in preparing medicines for treating cerebrovascular diseases
ActiveCN107595874AGood treatment effectReduce the effective doseOrganic active ingredientsNervous disorderTherapeutic effectEffective treatment
The invention discloses a pharmaceutical composition, which consists of butyphthalide and mecobalamine. The pharmaceutical composition, when used for treating cerebrovascular diseases and dementia, can achieve a synergistic effect, wherein with the adoption of the mecobalamine, the therapeutic effect of the butyphthalide can be obviously enhanced, so that the effective dosage of the butyphthalideis reduced and a using dose is reduced; and the pharmaceutical composition, when used for a long time, can reduce the occurrence of adverse reactions. Therefore, the pharmaceutical composition can take a more effective on treating the cerebrovascular diseases and dementia, and a therapeutic effect can be achieved at a relatively low dose, so that the pharmaceutical composition is suitable for clinical application.
Owner:SHIJIAZHUANG PHARMA GRP NBP PHARMA CO LTD
Anti-breeding rodenticide
InactiveCN103125530AReduce in quantityImprove palatabilityBiocideChemosterilantsInterstitial cellBiology
The invention discloses an anti-breeding rodenticide. Melia azedarach oil is served as an anti-breeding agent, and the weight percent of the melia azedarach oil in the anti-breeding rodenticide accouts for 0.08%-0.1%. Through researching the intrinsic rules and hormone regulation mechanism of mouse breeding as well as studying the toxicological and function mechanism of a vegetable anti-breeding agent, ideal anti-breeding agent-melia azedarach oil is screened. The anti-breeding rodenticide is low in effective dosage, makes mice infertile, and has the advantages of low toxicity index, high safety, no harm to human being and animals and no secondary poisoning. After the anti-breeding rodenticide is eaten 10 days later, main reproductive organs-testicles of male mice generate the following variation: the organ coefficient gets small, the sperm amount is reduced, the seminiferous tubule diameter is thinned, lumens are reduced, germinal epithelium thickness is thinned, and interstitial cells are decreased; and ovarial organ coefficient of female mice is obviously reduced, and the corpus luteum in an ovarial structure is contracted. Dead fetus are increased after male and female mice coition, and the breeding number is greatly decreased.
Owner:XIAN UNVERSITY OF ARTS & SCI
Pharmaceutical composition for nerve regeneration after cerebral arterial thrombosis as well as preparation method and application thereof
InactiveCN103989941AExact therapeutic effectExact preventive effectNervous disorderCardiovascular disorderDiseaseFritillaria thunbergii
The invention relates to a pharmaceutical composition for nerve regeneration after cerebral arterial thrombosis as well as a preparation method and application thereof, and the pharmaceutical composition for nerve regeneration after cerebral arterial thrombosis is provided for solving the problem of strong hepatotoxicity of existing chemical treatment medicaments for ischemic cerebrovascular disease. The pharmaceutical composition is prepared from the following raw materials: 15 parts of akebiaquinata, 6 parts of codonopsis pilosula, 10 parts of pomegranate bark, 10 parts of shiny-leaved yellowhorn shell, 10 parts of thunberg fritillary bulb, 20 parts of sealwort, 20 parts of the root of red-rooted salvia, 10 parts of glabrous sarcandra herb, 5 parts of ligusticum wallichii, 8 parts of seed of feather cockscomb, 15 parts of the root of fangji, 7 parts of burdock, 10 parts of the root of kudzu vine, and 10 parts of liquorice. The pharmaceutical composition can be used for promoting nerve regeneration after cerebral arterial thrombosis, so as to cure or prevent cerebral ischemia or cerebral infarction.
Owner:强红枫
Insecticidal spray EC and its preparation method
InactiveCN101305717AGuaranteed insecticidal activityIncreased toxicityBiocideArthropodicidesChemistryWater soluble
The invention relates to a disinsection sprinkling oil concentrate, which mainly composed of components with the following mass content: 40 to 65 percent of liquid paraffin, 2 to 5 percent of jinggangmycin, 1 to 3 percent of avermectin, 2 to 10 percent of tea saponin, 0.5 to 2 percent of water soluble extractive of plocamium telfairiae harv, 0.5 to 6 percent of water soluble extractive of tobacco leaves, 1.5 to 3 percent of emulsifier and the balancing amount of water; the emulsifier is mixture of sapn and tween with the mass ratio of 3: 1. The disinsection sprinkling oil concentrate of the invention has broad spectrum bacteriostasis and sterilization effect, quick action and long action are combined together, an efficacy period of 35 days can be maintained, no toxicity can be left on human and livestock, the environment can not be polluted, the effective drug consumption can be reduced, the generation of drug fastness can be suspended, and thereby the disinsection sprinkling oil concentrate can be used for the disinsection and the prophylaxis to fruits, vegetables, garden flowers, lawns, and urban gardens and trees.
Owner:戴康华
Traditional Chinese medicine gel cream for treating local rheumatic pain syndrome and preparation method thereof
InactiveCN104997981AExcellent adhesionStimulation withoutAnthropod material medical ingredientsHydroxy compound active ingredientsCross-linkTherapeutic effect
The invention discloses a traditional Chinese medicine gel cream for treating a local rheumatic pain syndrome and a preparation method thereof. The traditional Chinese medicine gel cream comprises a backing layer, a cream layer containing the traditional Chinese medicine and a cover lining, the cream layer containing the traditional Chinese medicine is prepared from, by weight, 1-5 parts of medicine extract, 1-5 parts of fine stuff, 20-30 parts of skeleton materials, 10-15 parts of agglutinants, 40-50 parts of humectant, 3-6 parts of filler, 0.2-0.5 part of a cross-linking agent and 0.3-0.6 part of a crosslinking accelerator. According to the traditional Chinese medicine gel cream for treating the local rheumatic pain syndrome and the preparation method thereof, the prepared traditional Chinese medicine gel cream has no stimulation and allergic reaction to skins, the adhesive force is good, anti-inflammatory and analgesic functions are achieved, the effect appears earlier, the dosage is low when the effect appears, the therapeutic effect is good, and the traditional Chinese medicine gel cream can be produced on a large scale.
Owner:JIANGSU 707 NATURAL PHARMA
Flowering day lily extract, preparation method and usage of flowering day lily extract, and antidepressant drug combination
PendingCN110522834ASimple stepsSignificant antidepressant effectNervous disorderPlant ingredientsDaylilyIntestinal microorganisms
The invention belongs to the technical field of natural medicine, and particularly relates to a flowering day lily extract, a preparation method and usage of the flowering day lily extract, and an antidepressant drug combination. The invention discloses the simple, economic and environment protective preparation method of the flowering day lily extract, and products of the preparation method, andfurther discloses application of the flowering day lily extract to preparation of antidepressant drug, and the antidepressant drug combination taking the flowering day lily extract as an active substance. The usage is verified through pharmacology experiment. According to the flowering day lily extract, the preparation method and usage of the flowering day lily extract, and the antidepressant drugcombination, application value of the flowering day lily is greatly developed, an intestinal microbial metabolites hypothesis is firstly adopted and applied to the flowering day lily extract, it is indicated that the flowering day lily extract can obviously influence intestinal microbe of a mice for treating depression, and good application prospects are achieved.
Owner:绿之韵生物工程集团有限公司
Difunctional molecular compound for inducing degradation of PD-L1 protein as well as preparation and application of difunctional molecular compound
PendingCN114573563AReduce the effective doseNo need for direct inhibition of functional activityOrganic active ingredientsOrganic chemistryAutoimmune conditionProtein target
The invention discloses a bifunctional molecular compound for inducing degradation of PD-L1 protein as well as preparation and application of the bifunctional molecular compound, and belongs to the technical field of chemical biology. Relates to a difunctional molecule compound for inducing degradation of PD-L1 protein as shown in a structural formula (I), a structural formula (II), a structural formula (III), a structural formula (IV) and a structural formula (V) or a pharmaceutically acceptable salt, hydrate or prodrug thereof, the compound takes PD-L1 as a target protein binding ligand, can degrade PD-L1 protein in a targeted manner, can be used as a PD-L1 protein targeted degradation agent, and has a good application prospect through research. And a very potential treatment scheme can be provided for PD-L1 mediated infection, tumors, autoimmune diseases and / or other diseases. In the structural formula (I), B and L in each structural formula are described in the specification.
Owner:SHENYANG PHARMA UNIVERSITY
Cyantraniliprole and chlorfenapyr suspending agent and preparation method thereof
InactiveCN103636612AIncrease profitSmall particlesBiocideAnimal repellantsChlorfenapyrSuspending Agents
The invention is suitable for the technical field of pesticide preparations and provides a cyantraniliprole and chlorfenapyr suspending agent and a preparation method thereof. The cyantraniliprole and chlorfenapyr suspending agent comprises the following components in percent by mass: 1%-50% of cyantraniliprole, 1%-50% of chlorfenapyr, 2%-10% of a dispersing agent, 1%-5% of a wetting agent, 0.2%-1% of a de-foaming agent, 0-10% of an anti-freezing agent, 0.1%-5% of a thickening agent, 0.1%-2% of a mildew preventive, 0-2% of a PH regulator and the balance of deionized water. The cyantraniliprole and chlorfenapyr suspending agent disclosed by the invention has the characteristics such as small preparation particles, narrow particle diameter distribution, long-term stable storage, no precipitation and extremely small water bleeding amount, can increase the utilization rate of active ingredients and can avoid pollution of normal preparations on environment; besides, the preparation process is simple and environment-friendly.
Owner:李视辉
4-methylpyrrole substituted indolone derivative and preparation method and medical application thereof
ActiveCN112321568APrevent proliferationGood curative effectOrganic active ingredientsOrganic chemistryAcute myeloid leukemiasSunitinib
The invention discloses a 4-methylpyrrole substituted indolone derivative, and a preparation method and medical application thereof. The invention relates to the field of medicinal chemistry. Comparedwith a compound 10d discovered in the earlier stage, the 4-methylpyrrole substituted indolone derivative disclosed by the invention has better chemical stability, higher selectivity on FLT3-ITD, moreideal pharmacokinetic characteristics and stronger in-vivo anti-tumor activity, and particularly has lower effective dose for treating acute myeloid leukemia. Under the same dosage, the tumor inhibition rate is obviously superior to that of compounds 10d and sunitinib, and the drug resistance is not easy to generate.
Owner:NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Lepidoptera insect insecticide synergist
ActiveCN105766947AReduce dosageImprove insecticidal effectBiocideDead animal preservationAdditive ingredientOrder Lepidoptera
The invention discloses a lepidoptera insect insecticide synergist. Active ingredients of the lepidoptera insect insecticide synergist include iso-ascaridole, alpha-terpinene and germacrene B, a mass concentration ratio of the iso-ascaridole to the alpha-terpinene to the germacrene B in a solvent is 1-20:1-10:1-15, and the active ingredients can be extracted from dysphania ambrosioides or chenopodium aristatum. When the insecticide synergist is used for killing lepidoptera insects, a volume percentage concentration of the iso-ascaridol, the alpha-terpinene and the germacrene B in an insecticide is 1-15%. According to pharmacodynamic tests, insecticide efficacies can be remarkably improved by consumption of a small quantity of the lepidoptera insect insecticide synergist, and insecticide consumption can be reduced by 20-45% under equal control effects, so that insecticide consumption is effectively reduced, drug resistance of harmful organisms is overcome and weakened, environment pollution is reduced, and remarkable economic benefit and environment protection significances are achieved.
Owner:INST OF PLANT PROTECTION FAAS
Novel application of salacia prinoides
InactiveCN105816487AInhibits glycogen phosphorylase activityReduce the effective doseMetabolism disorderFood preparationGlycogen phosphorylase activityClinical efficacy
The invention relates to an application of salacia prinoides in preparation of a glycogen phosphorylase inhibitor product. The salacia prinoides preferably selects dried stems of salacia prinoides (Wild.)DC. The invention also provides a composition capable of inhibiting activity of glycogen phosphorylase, which takes an original medicinal material or its decoction pieces or its extract product as an active component, and a pharmaceutically acceptable auxiliary material is added. The composition or its preparation can be used for inhibiting activity of glycogen phosphorylase, and clinically used for preventing and / or treating type II diabetes. The product can be taken as health food or food, and has high security. The preparation method is simple, and the production having the clinical curative effect is obtained by employing a conventional extraction separating technology.
Owner:周亚伟
Use of 2,2'-dipyridine N-oxide disulfur for preparing anti-tumor drug
InactiveCN1709250AEffective suppressionReduce the effective doseOrganic active ingredientsCisplatinNormal cell
The present invention relates to a new application of 2.2'-dipyridine N-oxide disulfur in preparation of antitumor medicine. 2.2'-dipyridine N-oxide disulfur can effectively inhibit and kill tumor cell, and its cytotoxity for normal cell is low, relatively to currently frequently-used antitumor medicine cisplatin and doxorubicin its action for poisoning tumor cell is more obvious, it can be used for preparing medicine for clinically-curing tumor.
Owner:NANJING NORMAL UNIVERSITY
Application of pyridine sulfonamide phosphate compound in preparation of anti-encephaledema medicine
PendingCN114796241ALower intracranial pressureInhibitory activityOrganic active ingredientsNervous disorderCerebral herniaPhosphoric acid
The invention relates to application of a pyridine sulfonamide phosphate compound or a pharmaceutical composition containing the pyridine sulfonamide phosphate compound in preparation of an anti-encephaledema drug. The pyridine sulfonamide phosphate compound can quickly reduce intracranial pressure, is used for treating encephaledema caused by various reasons and preventing cerebral hernia, is high in safety, has no serious adverse effects such as liver and kidney injury and the like, is expected to become a novel clinical anti-encephaledema medicine, and has a very wide clinical application prospect.
Owner:SHANGHAI XUNHE PHARMA TECH CO LTD
Bupirimate.boscalid suspoemulsion and preparation method thereof
InactiveCN104472492AReduce dosageMeet the requirements for the development of green and environmentally friendly pesticidesBiocideFungicidesDiseaseSclerotinia
The invention discloses a bupirimate.boscalid suspoemulsion and a preparation method thereof. The bupirimate.boscalid suspoemulsion is prepared from the following components in percentage by weight according to a formula: 5-20 percent of bupirimate and 5-20 percent of boscalid. According to the bupirimate.boscalid suspoemulsion and the preparation method disclosed by the invention, by compounding the bupirimate and the boscalid and adopting a reagent form of suspoemulsion, the two active ingredients have synergistic interaction, so that the sterilization treatment spectrum action is enlarged, the effect of controlling germs is remarkably improved, the drug resistance problem of the germs is relieved, the therapeutic effect on diseases including powdery mildew, botrytis cinerea, sclerotinia and various rot diseases of crops including rapes, grapes, fruit trees, vegetables and field crops is good, the dosage form is environmentally friendly, and pollution and damage to the environment are reduced.
Owner:孙素一
A kind of pharmaceutical composition containing 4-hydroxyl-2-oxo-1-pyrrolidineacetamide and its application
ActiveCN103877081BReduced activityElevated MDA contentNervous disorderHydroxy compound active ingredientsPharmacy medicineTherapeutic effect
The invention belongs to the technical field of medicinal products, and particularly relates to a medicinal composition containing 4-hydroxy-2-oxo-1-pyrrolidine acetamide and application thereof. A 4-hydroxy-2-oxo-1-pyrrolidine acetamide-borneol medicinal composition provided by the invention has a synergistic treatment effect on neuromotor dysfunction and impaired memory dysfunction vascular dementia and senile dementia, and the treatment effect of oxiracetam can be improved remarkably by using borneol, so that the acting dose of oxiracetam is reduced, the dosage is reduced, and adverse reactions are reduced after long-time application. By adopting the medicinal composition, intelligence disturbance of a dementia patient can be treated more effectively, and a treatment effect can be achieved with a small dosage. The medicinal composition is suitable for clinical use.
Owner:CSPC OUYI PHARM CO LTD +1
Traditional Chinese medicine composition for treating ischemic cerebrovascular disease and preparation method thereof
ActiveCN103623109BExact therapeutic effectGood treatment effectUnknown materialsCardiovascular disorderDiseaseTherapeutic effect
Owner:启东市丰武农副产品专业合作社
Preparation of compound of Au and anti-apoptotic protein antagonistic peptide and application of compound in synergistic induction of tumor cell apoptosis
ActiveCN114432340AReduce the effective doseGood curative effectPeptide/protein ingredientsInorganic active ingredientsLymphocytic cellAPOPTOGENIC PROTEIN
The invention discloses preparation of a compound of Au and an anti-apoptotic protein antagonistic peptide and application of the compound in synergistic induction of tumor cell apoptosis, and relates to the field of anti-tumor drugs. Mixing a gold salt solution with the anti-apoptotic protein antagonistic peptide containing sulfydryl; under the conditions of certain temperature and pH, redox reaction is carried out, high-valence Au ions are reduced into Au atoms or monovalent Au ions, and Au acts on sulfydryl of polypeptide to form a compound AuP; the sulfydryl-containing anti-apoptotic protein antagonistic peptide is selected from polypeptides with an intracellular anti-apoptotic protein antagonistic function. The AuP compound has broad-spectrum anti-tumor activity, and compared with a common peptide-gold compound or gold compound, the AuP compound can inhibit the activity of thioredoxin reductase and antagonize the function of high-expression anti-apoptotic protein at the same time, the single-drug double-target synergistic effect is achieved, and the curative effect is remarkably improved. The compound can be used for treating various malignant tumors such as chronic lymphocytic leukemia, acute monocytic leukemia and non-Hodgkin lymphoma.
Owner:BEIJING UNIV OF TECH
Insect repellent agent for flower planting and preparation method of insect repellent agent
InactiveCN108419808AGood control effectLong durationBiocideExcrement fertilisersEconomic benefitsInsect repellants
The invention relates to an insect repellent agent for flower planting and a preparation method of the insect repellent agent. The insect repellent agent is prepared from raw materials in parts by weight as follows: 20-25 parts of tobacco waste, 15-20 parts of branches and leaves of tea trees, 15-20 parts of cortex meliae, 10-15 parts of shells of bamboo shoots, 10-15 parts of branches and leavesof gingkoes, 8-12 parts of Chinese honeylocust fruits, 5-10 parts of radix euphorbiae lantu, 4-8 parts of wormcast, 3-6 parts of plant ash and 2-5 parts of auxiliaries. The insect repellent agent prepared with the method is good in control effect and long in lasting period, has low probability of producing insecticide resistance, is green, pollution-free and harmless to body health and cannot pollute the environment; the preparation method is simple and easy to operate, the cost is low, efficacy of the insect repellent agent can be remarkably improved, effective dosage is effectively reduced,insecticide resistance of harmful organisms is overcome and delayed, the application range of the insect repellent agent is wide, potential value of plant resources is sufficiently utilized, and the insect repellent agent has remarkable economic benefit and environmental protection significance.
Owner:夏文秀
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com