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Novel application of salacia prinoides

A technology of salacia and medicinal materials, applied in the field of medicine, can solve problems such as the shortage of salacia, and achieve the effects of low onset dose, safety, non-toxic side effects, and wide distribution

Inactive Publication Date: 2016-08-03
周亚伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Salacia is mainly distributed in Hainan, Guangdong, and Guangxi, and is rich in resources. However, the research on Salacia at home and abroad is still very scarce, and we need to further explore
[0006] However, there has not been any research report on Salacia in inhibiting the activity of glycogen phosphorylase

Method used

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  • Novel application of salacia prinoides
  • Novel application of salacia prinoides
  • Novel application of salacia prinoides

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 5

[0037] Preparation of Example 1 Salacia chinensis Crude Extract 1

[0038] Take the dried cane of Salacia, crush it, weigh about 20g, extract 3 times with 10 times the amount of water, the extraction time is 1h, 0.5h, 0.5h, combine the extracts, concentrate under reduced pressure to 10ml, the specification is 2 : 1 (g / ml).

Embodiment 2 5

[0039] Preparation of Example 2 Sarcocarpus Crude Extract 2

[0040] Take the dried rhizome of Salacia salacia, crush it, weigh about 20g, extract 3 times with 10 times the amount of water, the extraction time is 1h, 0.5h, 0.5h respectively, combine the extracts, concentrate under reduced pressure to 10ml, and the specifications are 2: 1 (g / ml).

Embodiment 3 5

[0041] The preparation of embodiment 3 salacia ethanol crude extract 1

[0042] Take the dried cane of Salacia, crush it, weigh about 20g, extract 3 times with 10 times the amount of 95% ethanol, the extraction time is 1h, 0.5h, and 0.5h respectively, combine the extracts, concentrate under reduced pressure to 10ml, specifications It is 2:1 (g / ml).

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Abstract

The invention relates to an application of salacia prinoides in preparation of a glycogen phosphorylase inhibitor product. The salacia prinoides preferably selects dried stems of salacia prinoides (Wild.)DC. The invention also provides a composition capable of inhibiting activity of glycogen phosphorylase, which takes an original medicinal material or its decoction pieces or its extract product as an active component, and a pharmaceutically acceptable auxiliary material is added. The composition or its preparation can be used for inhibiting activity of glycogen phosphorylase, and clinically used for preventing and / or treating type II diabetes. The product can be taken as health food or food, and has high security. The preparation method is simple, and the production having the clinical curative effect is obtained by employing a conventional extraction separating technology.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the new use of Salacia salacia as a glycogen phosphorylase inhibitor, which can be used to prevent and / or treat type 2 diabetes. Background technique [0002] Salaciaprinoids, scientific name: Salaciaprinoids (Willd.) DC., also known as Salaciaprinoids (Willd.) DC., is a plant of the genus Salaciaprinoids in the wing rattan family. Salacia is used as medicine with its roots among the people, according to "Chinese Materia Medica": Salacia has astringent taste, warm in nature, has the effect of expelling wind and dampness, promoting menstruation and promoting blood circulation, and can cure rheumatic arthralgia, blood stasis and low back pain. Modern pharmacological studies have found that most of the water-soluble components of the roots or stems of Salacia plants have the effects of lowering blood sugar, protecting the liver, anti-oxidation, reducing fat and losing weight, antib...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P3/10A23L1/29A23L1/30
Inventor 周亚伟
Owner 周亚伟
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