The invention relates to the technical field of blood storage equipment, in particular to an automatic blood access box structure. The automatic blood access box structure comprises a box body, a cover plate, a drive mechanism, a partition plate, a blocking space, a floating plate, a blocking block, a limiting slot, a floating column and an elastic part. The automatic blood access box structure has the beneficial effects that: while the cover plate is opened, the elastic block abuts against the blocking block, so that the floating plate moves upwards, and therefore, hands of medical staff do not need to extend into the box body while the medical staff places or takes a blood storage bag, and low-temperature harm, on the medical staff, is at least reduced to certain extent; after the coverplate is covered, the surface of the cover plate abuts against the upper end of the floating column for driving the floating plate to move downwards, so that the floating plate is automatically blocked into the blocking space, and therefore, operations are convenient, and the structure is simple; and a drive element acts to drive a connector to swing, so that the cover plate is driven to rotate along a hinged part with the box body, and therefore, opening and closing of the cover plate are realized, and the medical staff does not need to manually open the box.