The invention discloses an inorganic-inorganic
nano hybrid material of a bimodal mesoporous core-shell structure as well as a preparation method and an application of the inorganic-inorganic
nano hybrid material. The bimodal mesoporous inorganic-inorganic
nano hybrid material of the core-shell structure is prepared by the following steps: firstly, with the presence of a surfactant, reducing
metal salt by virtue of
ascorbic acid, so that mesoporous
inorganic nanoparticles are obtained; then, covering the surface of hexadecyl trimethyl
ammonium bromide, which serves as a surfactant, with a layer of mesoporous
silicon dioxide; covalently
grafting diethyltriamine pentaacetic acid after modifying a mesoporous
silicon dioxide shell layer by virtue of amino; and finally, coordinating with
metal ions, so that the bimodal mesoporous inorganic-inorganic nano
hybrid material of the core-shell structure is obtained. The
prepared material has the core-shell material, wherein a core is constituted by the mesoporous
inorganic nanoparticles and a shell is formed by the mesoporous
silicon dioxide shell layer, and the surface of the mesoporous
silicon dioxide shell layer is hybridized and modified by virtue of inorganic metals. The inorganic-inorganic nano
hybrid material has the advantages of being uniform in dimension, good in
biocompatibility and the like, and the inorganic-inorganic nano
hybrid material is high in
optical stability, high in photo-thermal conversion rate and high in
magnetic resonance imaging resolution ratio; and integration of
magnetic resonance imaging and photo-
thermal therapy can be achieved.