51results about How to "Enhanced signal amplification" patented technology

A small, low power consumption light amplifier using stimulated Raman scattering is provided. A Raman active section 18 and a rough surface metal part 21 are provided on one end face of an optical fiber 11, excitation light is irradiated onto the rough surface metal part 21, surface plasmon is generated and signal light 15 is amplified into amplified signal light 16 using stimulated Raman scattering in the interface between the rough surface metal part 21 irradiated with the signal light 15 which has propagated through the core 12 and the Raman active section 18.

A method of reducing distortion in the output of an amplifier is provided. The method comprises subtractively combining baseband error signals with the appropriate phase shift with baseband input signals, the baseband error signals generated by subtractively combining delayed fed-forward portions of the baseband input signals with baseband converted portions of a fed-back amplified output signal, the amplified output signal being a distorted replica of combined up-converted baseband input signals. The baseband error signals being filtered prior to the combining function, and also providing inputs to a controller which adjusts active elements of the amplification and fed-back paths in order to minimize the distortion within the output of the amplifier.

In multilayer optical discs and high-speed optical discs, the amount of reproduction light per unit time greatly decreases and the reproduction signal quality (S / N) significantly drops due to the low effective reflectivity and the short read time of the medium. These problems are solved by causing reflected signal light from the optical disc and reference light, which is separated from the same light source and introduced into a detector without being shone onto the optical disc, to interference with each other on the detector. Detector outputs having four different interference states are simultaneously obtained, the interference states being displaced at intervals of 90 DEG in terms of the phase relationship between the reference light and the signal. Based on a operation of the four detector outputs, a reproduction signal can be obtained that is stable at all times and amplified with high quality, even when there is an optical path length variation due to disc undulations.

The invention provides a method for preparing an enzyme labelling antibody. The method comprises the following steps of: concentrating a colloidal gold solution, and then adjusting the pH value of the concentrated colloidal gold solution to be slightly greater than the pH value of an isoelectric point of an enzyme for labelling; adding an aqueous solution of the enzyme for labelling into the colloidal gold solution, mixing the solutions, and then connecting the antibody to molecules of the enzyme on the surface of colloidal gold by a bifunctional reagent; and carrying out centrifugation to obtain an enzyme labelling colloid gold compound antibody. In the method, enzyme labelling on the colloidal gold is accomplished in a direct-absorption simple mode; the separation of the enzyme and a coupling agent and separation purification after connection of the antibody can be finished only by the simple centrifugation without the complicated and high-loss expensive steps of gel filtration, dialysis or affinity chromatography; by concentration operation prior to enzyme absorption by the colloid gold, the connection amount of a connected reagent can be increased, and the concentration of gold colloid particles in the enzyme labelling colloid gold compound antibody can be increased simultaneously; and the enzyme labelling colloid gold compound antibody is accordant with the characteristic.

An amplifier optical fiber comprising a central core of a dielectric matrix doped with at least one element ensuring the amplification of an optical signal transmitted in the fiber and a cladding surrounding the central core and suitable for confining the optical signal transmitted in the core. The fiber also comprises metallic nanostructures suitable for generating an electronic surface resonance in the dielectric matrix of central core, the wavelength of said electronic surface resonance corresponding to an excitation level of the element ensuring the amplification.

A vibration sensor comprising a pressure detecting arrangement adapted to detect generated pressure variations, and provide an output signal in response to the detected pressure variations, and a pressure generating arrangement adapted to generate pressure variations in response to movements thereof wherein the pressure generating arrangement is secured to an exterior surface portion of the pressure detecting arrangement. In a preferred embodiment the pressure detecting arrangement comprises a stand-alone and self-contained MEMS microphone unit comprising a MEMS microphone cartridge and a signal processing unit.

An interference type optical head and an optical disk device that can easily adjust an optical path length difference of a couple of lights, ensure higher signal amplification effect, and are suitable for reduction in size are provided in order to improve a regeneration signal quality with amplification of signal in the case where reflectivity of each layer must be lowered and relative noise for the signal increases because read speed is high in a multilayer optical disk. In view of essentially improving an S / N ratio of the regeneration signal in high-speed rotation of a multilayer disk, a plurality of interference phases are generated and an optical system for differential calculation has been reduced in size with an angular selective polarization conversion element in the optical disk device for amplifying the signal with interference of the light not radiated to the disk with the reflected light from the disk. Moreover, adjustment of reflection mirror angle of the reference light is no longer required by using a corner cube prism as the reference light reflection mirror and highly accurate signal detection can also be realized with a simplified structure.

The invention discloses an electric energy management comprehensive monitoring system, and belongs to the technical field of power utilization monitoring. The electric energy management comprehensivemonitoring system comprises a user power utilization monitoring unit, wherein an output end of the user power utilization monitoring unit is electrically connected with a power distribution station monitoring unit, the power distribution station monitoring unit comprises a draught fan control module, an air conditioner control module, a gas monitoring unit, a sound-light alarm unit, a water levelmonitoring unit and an ultrasonic water level monitoring unit, and the fan control module is bidirectionally and electrically connected with the air conditioner control module. The starting, stoppingand running states of a transformer temperature fan are monitored in real time by monitoring the temperature in a transformer, and the air-conditioning temperature can be automatically adjusted, so that the temperature control and adjustment capacity of a transformer substation can be remarkably improved, the temperature of the transformer substation does not need to be controlled through manual inspection, the electric energy management comprehensive monitoring system can automatically adapt to the internal power of the transformer substation to change the heat dissipation strategy, improvesthe monitoring and management capability of the temperature of the transformer substation, remarkably reduces the manpower cost, and improves the regulation and control safety and stability.

The invention provides a digital miRNA analysis method for loop-mediated isothermal amplification in an emulsion. According to the technical scheme, primer-labeled magnetic beads are used as the carrier to undergo a loop-mediated isothermal amplification reaction in stable emulsion droplets; after reaction of the magnetic beads, lots of amplification products are generated and a complementary fluorescently-labeled primer is captured; after demulsification, reacted magnetic beads are collected; and through a microscope and a flow cytometer, digital nucleic acid analysis of target DNA / Mrna is realized. The establishment of the digital miRNA analysis method provides a digital miRNA analysis means with simple process, stable signals and high sensitivity and accuracy for the reaches on genetic diagnosis, gene therapy, etc.

The invention provides a finned bipolar junction transistor and a manufacturing method thereof. The finned bipolar junction transistor comprises a substrate, a fin part located on the substrate as a base region and comprising mutually separated first and second regions, a collector region located on the first region, and an emitter region located on the second region. The finned bipolar junction transistor manufactured by the method is characterized in that a PN junction formed between the base region and the emitter region has relatively large area, and the area of the PN junction is adjustable in a large range.

The invention discloses a preparation method of a paper-based ratio photoelectrochemical biosensor for detecting microRNA. Gold nanoparticles grow on the surfaces of paper-based dual electrodes composed of a working electrode and an internal reference electrode, then cuprous oxide is electrodeposited, graphene quantum dots and silver iodide nanoparticles are sensitized, and a photocurrent signal is enhanced; when the target microRNA exists, DNA probes output by microRNA-induced double-stranded specific nuclease reactions with different concentrations and constant concentrations are respectively incubated on the surfaces of the working electrode and the internal reference electrode; DNA bridge chains and DNA hairpins H1 and H2 on the surface of the electrode are combined to form a DNA bridge nano structure through induction; and the silver iodide nanoparticles marked at the end parts of the H1 and the H2 are far away from the surface of the electrode, so that the photocurrent signal isreduced, and the sensitive detection of the microRNA is realized based on the ratio of the working current signal to the internal reference current signal.

The invention discloses a quick identifying method for positive and negative food-borne pathogenic bacteria.The method comprises the steps that a graphite carbonization nitrogen / gold or graphite carbonization nitrogen / silver nanoparticle composite is adopted as enhancing reagent, special structure differences of cell walls of the positive and negative food-borne pathogenic bacteria are used, and by means of a surface enhanced raman spectrum and a chemometrics method, successful quick identification is conducted on the positive and negative food-borne pathogenic bacteria.According to the method, sensitivity is high, reliability is strong, the detecting speed is high, and cost is low; the method can be used for large-scale on-line detection of the positive and negative food-borne pathogenic bacteria and is suitable for the technical fields of food safety, environment monitoring and the like.

The invention relates to a measuring device for acoustic characteristics and flow characteristics of a muffler in a flow environment. The transmission loss and the pressure loss of the muffler in a flow field are measured. The device comprises a measurement environment generating module, a measurement variable generating module and a data acquisition analysis module. The tail end of the measurement environment generating module is connected with the muffler. The measurement environment generating module is used for generating noise and the flow field. The front end of the measurement variable generating module is connected with the muffler. The measurement variable generating module is used for changing the measurement environment to generate a measurement variable. The data acquisition analysis module is connected with the measurement environment generating module and the measurement variable generating module, and is used to acquire the pressure loss of the muffler in the flow field by acquiring and analyzing an air pressure signal, and acquire the transmission loss of the muffler in the flow field by acquiring and analyzing sound pressure signals under different measurement variables. Compared with the prior art, the measuring device provided by the invention can measure the acoustic characteristics of the muffler in the flow field environment, can simultaneously measure the transmission loss and the pressure loss, and has the advantages of high measurement efficiency, accurate measurement accuracy and the like.

The invention provides a finned bipolar junction transistor and a manufacturing method thereof. The finned bipolar junction transistor comprises a substrate, a fin part located on the substrate and doped with impurities as a first region, a base region located on the first region, and a second region located on the base region or in the base region, wherein the first region serves as an emitter region, while the second region serves as a collector region, or the first region serves as the collector region, while the second region serves as the emitter region. The finned bipolar junction transistor is characterized in that a PN junction formed between the base region and the emitter region has relatively large area, and the area of the PN junction is adjustable in a large range.

The present invention provides an optical head and an optical disc apparatus. In an interference-type optical head and optical disc apparatus, accordance of optical axes of signal light of a reflective light form an optical information medium and a reference light interfered with the singal light is difficult, and interference light is hard to be generated with high accuracy. Reference light for interference with signal light from an optical information recording medium is displaced and reflected by a corner cube prism or the like with high accuracy. The signal light and the displaced reference light are made parallel with each other with high accuracy. The signal light and the reference light are each split using a polarization splitter to generate interference light. Thus, regeneration signals are stabilized. Accordingly, an interference-type optical head and optical disc apparatus of higher quality than conventional ones can be provided.

The present invention belongs to the field of photoelectric detection and imaging, and especially relates to an image element structure capable of improving frame transfer CCD response. The image element structure comprises a substrate, a plurality of parallel vertical transfer electrodes, A CCD buried-channel region, a protection ring and a channel resistor; a p-type signal amplification region and an n-type signal amplification region are arranged in order between the substrate and the CCD buried-channel region; the vertical transfer electrodes are connected with the upper portion of the CCDburied-channel region, one side of each vertical transfer electrode is connected with a signal amplification control electrode through a dielectric layer; and the protection ring and the channel resistor are arranged respectively at the positions from left and right sides of the top portion of the substrate until the CCD buried-channel region. The image element structure capable of improving frame transfer CCD response can change the photosensitive responsivity of the CCD image element in real time by changing the injection concentration of the signal amplification structure and the applied voltage so as to allow the CCD to more flexibly select the signal amplification capacity at different light intensities of incident light and improve the imaging detection adaptation of the CCD for different light intensity environments.

The invention discloses a functionalized temperature-sensitive polymer, a preparation method of same, and an application of same in (PTM) protein detection. The structure formula of the functionalizedtemperature-sensitive polymer is represented as the formula I, wherein R is CH2, r is 0 or 1, m is any natural number from 20 to 750, n is any natural number from 110-1120, and the structure in the specification is horse radish peroxidase unit. The functionalized temperature-sensitive polymer is a linear polymer, which is produced through a free radical polymerization reaction and has a large number of modificable loci. After functional modification, the temperature-sensitive polymer having a plurality of HRP and a large number of triphenyl phosphine groups can be produced. Compared with an antibody strategy in which only single HRP is carried in the prior art, increasing of numbers of the HRP and the triphenyl phosphine groups can effectively increase the combination capability between the polymer and azide-labeled target proteins and signal amplification effect of chemical-luminescence.

The invention relates to a non-diagnostic method for detecting GPC3 based on H-rGO-Pd NPs and Au NPs (at) rGO nanomaterials, which comprises the following steps: modifying Au NPs (at) rGO on the surface of SPE by adopting electro-deposition, and loading GPC3Ab on the surface of Au NPs (at) rGO / SPE by virtue of adsorption; the preparation method comprises the following steps: by taking an H-rGO-Pd NPs nano material as a carrier, preparing an H-rGO-Pd NPs-GPC3Apt detection probe, and constructing a sandwich type electrochemical aptamer sensor by utilizing specific binding of GPC3, GPC3Ab and GPC3Apt; a detection signal is amplified based on the effect of catalyzing silver deposition by the H-rGO-Pd NPs nano mimetic enzyme material, scanning is performed by adopting DPV of an electrochemical workstation, peak current is recorded, and GPC3 detection is realized.

The invention relates to the technical field of amplifying circuits. The invention provides a weak pulse signal amplification circuit and a tiny dust detector. The circuit comprises an input capacitor, an impact sensor, a charge-sensitive pre-amplification sub-circuit and a charge-sensitive post-amplification sub-circuit. The input capacitor and the impact sensor are electrically connected with the input end of the charge-sensitive pre-amplification sub-circuit; the charge-sensitive post-amplification sub-circuit and the charge-sensitive pre-amplification sub-circuit are cascaded to form a charge-sensitive amplification sub-circuit; the amplification factor of the charge-sensitive amplification sub-circuit is multiplied; the signal amplification capability of the charge-sensitive amplification sub-circuit is improved; when the impact sensor is in an idle state, the input capacitor is utilized to test the adaptation of the charge-sensitive amplification sub-circuit and the impact sensor, and when the impact sensor is in a detection state, the input capacitor prevents the performance of outputting a weak charge pulse signal to the charge-sensitive amplification sub-circuit so as to prevent the input capacitor from generating signal interference on the impact sensor.

The invention discloses a photoelectric detector based on dark current compensation and an erbium-doped optical fiber amplifier. The photoelectric detector comprises a photoelectric detection circuit, a temperature sensor and a compensation module. The output quantity of the photoelectric detection circuit is output to the compensation module, and the compensation module performs dark current power compensation on an optical power value obtained by fitting the output quantity of the photoelectric detection circuit according to the working temperature obtained by the temperature sensor to obtain detection optical power. The erbium-doped optical fiber amplifier comprises one or more photoelectric detectors, and at least one of the one or more photoelectric detectors is the photoelectric detector based on dark current compensation. According to the invention, dark current power compensation can be realized accurately and conveniently at low cost, and the detection precision of the photoelectric detector in a low detection power range is improved. The optical signal amplifier is high in precision, full in temperature and ultra-wide in photoelectric detection range, and is applied to long-distance communication of a core network and a backbone network.

A bias circuit includes first to fourth transistors and a phase compensation circuit. In the first transistor, a reference current or voltage is supplied to a first terminal, and the first terminal and a second terminal are connected. In the second transistor, a first terminal is connected to the first transistor, and a third terminal is grounded. In the third transistor, a power supply voltage is supplied to a first terminal, a second terminal is connected to the first transistor, and a bias current or voltage is supplied from a third terminal to an amplifier transistor. In the fourth transistor, a first terminal is connected to the third transistor, a second terminal is connected to the second transistor, and a third terminal is grounded. The phase compensation circuit is provided in a path extending from the fourth transistor to the third transistor through the second and first transistors.

A light beam emitted from a laser source is divided into a first light beam and a second light beam. An optical divider is further provided to separate a combined light beam of the first and second light beams into a first light bundle near the optical axis and a second light bundle in the edge portion and to diverge the first and second light bundles so that the first and second light bundles are individually detected by plural detectors. The first light beam is signal light focused on an optical information recording medium by an objective lens and reflected off the medium, and the second light beam is reference light not focused on the optical information recording medium. A focus error signal is then detected for the first light bundle for compensating focus error.

The invention relates to a novel wireless router for a communication network. The novel wireless router comprises a main body, a display screen, a power line interface and multiple state indicator lamps are arranged on a front face of the main body, an antenna, an antenna connecting rod, a reset button mechanism and multiple network cable interfaces are arranged on a back face of the main body, one end of the antenna connecting rod is fixed on the main body, the antenna is connected with the antenna connecting rod, the novel wireless router for the communication network blocks a reset button located at the bottom of an open slot by a sliding plate to isolate the reset button so as to prevent the reset button from being touched by mistake to cause unnecessary troubles, moreover, in a simple amplifying circuit, a first triode is used as high frequency wide-band amplifier, a common-collector amplifier composed of second triodes is used as an emitter follower, and a negative voltage power supply is used for supplying power, so that the signal amplifying ability is improved, an external communication device is guaranteed to realize stable connection with the router, and improve the signal transmission ability.

The invention relates to a functionalized micro-channel plate. The functionalized micro-channel plate is characterized in that a plurality of oblique up-down transparent micro-holes parallel to one another are arrayed in the micro-channel plate, and metal nanorod arrays are attached to the insides of the micro-holes. A biomolecular sensor is characterized by comprising a signal amplification device, an energy conversion device and a recognition device, wherein the signal amplification device is used for realizing the concentration detection of trace markers (concentration: -fg / mL) and even single molecules by virtue of the micro-channel plate; and the metal nanorod arrays are prepared in the micro-channel plate, and biological markers are detected by virtue of a Raman spectrum based on surface plasmon resonance of the metal nanorod arrays in the micro-holes of the micro-channel plate.

The invention discloses a genetic coding sensor for endogenous RNA (Ribonucleic Acid) imaging. The genetic coding sensor comprises an RNA sensing module and a fluorescent protein report module, wherein the RNA sensing module is degApt with stem-loop conformation, and the fluorescent protein report module is fused with fluorescent protein tDeg. According to the invention, target RNA can recover the active conformation of the degApt in the RNA sensing module so as to stabilize the fluorescent protein, so that the target RNA is imaged, and the expression and the dynamic state of the survivin mRNA and the lncRNA MALAT-1 in the living mammalian cell can be imaged. The genetic coding sensor for endogenous RNA imaging can be widely applied to RNA imaging of living cells and animals in biomedical research and clinical treatment.