219 results about "Ultrasound method" patented technology

The invention relates to the guidance, positioning and placement confirmation of intravascular devices, such as catheters, stylets, guidewires and other flexible elongate bodies that are typically inserted percutaneously into the venous or arterial vasculature. Currently these goals are achieved using x-ray imaging and in some cases ultrasound imaging. This invention provides a method to substantially reduce the need for imaging related to placing an intravascular catheter or other device. Reduced imaging needs also reduce the amount of radiation that patients are subjected to, reduce the time required for the procedure, and decrease the cost of the procedure by reducing the time needed in the radiology department. An aspect of the invention includes, for example, an endovenous access and guidance system. The system comprises: an elongate flexible member adapted and configured to access the venous vasculature of a patient; a sensor disposed at a distal end of the elongate flexible member and configured to provide in vivo non-image based ultrasound information of the venous vasculature of the patient; a processor configured to receive and process in vivo non-image based ultrasound information of the venous vasculature of the patient provided by the sensor and to provide position information regarding the position of the distal end of the elongate flexible member within the venous vasculature of the patient; and an output device adapted to output the position information from the processor.

Ultrasound methods of distinguishing ablated tissue from unablated tissue include scanning ablated tissue using Acoustic Radiation Force Impulse (ARFI) imaging. ARFI image data is generated based on the scanning. The image data includes a portion of increased stiffness representing the ablated tissue that is distinguishable from unablated tissue.

Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The scanning may comprise exposing the patient to a first type of ultrasound energy and then interrogating the patient using a second type of ultrasound energy. The targeting ligand preferably targets tissues, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The methods may be used to detect a thrombus, enhancement of an old or echogenic thrombus, low concentrations of vesicles and vesicles targeted to tissues, cells or receptors.

Methods and systems for assessing the effects of therapy on a patient include obtaining baseline and treatment ultrasound scans of a treatment area of a patient where the treatment ultrasound scans are taken subsequent to the baseline scan and at various times during a course of radiotherapy treatment sessions. The baseline and treatment ultrasounds are compared, and as a result a damage map representing cell death within the treatment area can be constructed.

An ultrasound method for visualization of quantitative data on a surface model is provided. The ultrasound method acquires ultrasound information from an object. The information acquired defines ultrasound images along at least first and second scan planes through the object and is stored in a buffer memory. The method then constructs a surface model of the object based on the ultrasound information. Timing information associated with local areas on the object is determined. The surface model and timing information are displayed with the timing information being positioned proximate regions of the surface model corresponding to local areas on the object.

A protocol-based ultrasound method is provided. The ultrasound method provides a template comprised of cells. Each of the cells contain scan parameters defining a scan sequence for acquisition of ultrasound images along one or more scan planes through an object. Prior to scanning the object, parameter values for the scan parameters associated with cells in the template are entered to define the scan sequences along at least two scan planes. The object is scanned with an ultrasound probe to automatically and successively acquire ultrasound images along at least two scan planes based on the parameter values for the scan parameters in the cells. The method displays ultrasound images of an object that is changing states in accordance with a protocol. Each of the ultrasound images is acquired along a corresponding scan plane through the object. A collection of ultrasound images is provided. Each of the ultrasound images is acquired along an associated scan plane while the object is in an associated state. The display is segmented into at least two quadrants. A corresponding ultrasound image is presented in the quadrants, wherein co-displayed ultrasound images correspond to one of a common state of the object and a common scan plane through the object.

Methods and assemblies for the construction of liquid-phase alloy nanoparticles are presented. Particle formation is directed by molecular self-assembly and assisted by sonication. In some embodiments, eutectic gallium-indium (EGaIn) nanoparticles are formed. In these embodiments, the bulk liquid alloy is ultrasonically dispersed, fast thiolate self-assembly at the EGaIn interface protects the material against oxidation. The assembly shell has been designed to include intermolecular hydrogen bonds, which induce surface strain, assisting in cleavage of the alloy particles to the nanoscale. X-ray diffraction and TEM analyses reveal that the nanoscale particles are in an amorphous or liquid phase, with no observed faceting.

Systems and methods for visualizing lesions in tissue are provided. The systems and the system and methods exploit the differential scattering of ultrasound waves by normal and lesioned tissues to image the lesions. Spectrum analysis of the harmonics in diagnostic ultrasound waves that are differentially backscattered from lesioned and normal tissues provides image contrast and resolution.

The invention discloses a method of one-step synthesizing fluorescent carbon dots with corncobs as a carbon source and belongs to the technical field of synthesis of fluorescent carbon dots. In the technical scheme, the method of one-step synthesizing the fluorescent carbon dots with the corncobs as the carbon source includes the following steps: mixing pre-treated corncobs, ethanediamine and deionized water uniformly, and performing heating reaction to prepare the fluorescent carbon dots through hydrothermal method, microwave method and ultrasound method; or directly calcining the pre-treated corncobs to obtain the fluorescent carbon dots. The raw materials are easy to obtain. The method is simple in processes, is mild in reaction conditions, is simple in operation and is free of toxic reagents. The fluorescent carbon dots can not only be used as a fluorescent probe to detect substance content but also be used in the researching fields of bio-markers, bio-imaging, photo-catalysis, photo-electronic devices, bio-sensors and the like.

The invention relates to a judging method of an incompactness defect in a node of a concrete structure by detection by an ultrasonic method. On the basis of the traditional method for detecting the concrete defect by the ultrasonic method, besides an acoustic velocity and a head wave amplitude, two variable acoustic parameters, namely a complex frequency difference and a cross-correlation coefficient, are added; each acoustic parameter is processed into an acoustic parameter judging factor and each acoustic parameter judging factor is processed into a normalized comprehensive acoustic parameter judging factor; a position detecting chromatogram is drawn out according to the comprehensive acoustic parameter judging factor; and the position and range of a suspicious defect are determined according to a red area in the chromatogram. By the method, the compactness quality distribution of concrete can be directly and accurately described; errors and judgment loss caused by adoption of a single acoustic parameter for judgment can be avoided or reduced; and the difficulty in final judgment when the judgment result of the single acoustic parameter is inconsistent is also avoided. The judging method can be widely applied to the judgment of the incompactness defect in the node of the concrete structure or other complex structures.

Ultrasound methods and apparatus for mixing two or more different liquids are disclosed. The ultrasound methods and apparatus may mix varied components including drugs, polymers, and coatings for application to a variety of medical apparatus surfaces. The apparatus and technique can generate a proper mixture which is uninterruptedly / continuously delivered to the surface of the medical apparatus. The apparatus may include specific ultrasound transducer / tip configurations which may allow for the mixing of different liquids in a mixing camera located inside of the vibrating tip. The apparatus and methods of the present invention may mix different drugs, applying them to stent surface using different effects like ultrasound cavitation and radiation forces. Furthermore, the disclosed methods and apparatus may generate a mixture and may deliver a targeted, gentle, highly controllable dispensation of continuous liquid spray which can reduce the loss of expensive pharmaceuticals.

An ultrasound method and medical devices using same provide for various techniques of sampling blood flow velocity, e.g., at several sampling rates. To minimize the energy required for ultrasound monitoring, pulsed Doppler signal packages provided by a pulsed ultrasound circuit are switched in such a way that the repetition rate is the lowest possible and yet sufficiently high to be able to record the blood flow velocity within the heart. For example, an ultrasound circuit may be activated only within a part of the cardiac cycle designated as the Doppler Measurement Interval (DMI); the ultrasound circuit may be switched between an on state and an off state during the DMI; and / or the ultrasound circuit may also be switched on and off in different sampling modes: detection mode and measurement mode (e.g., using different sampling rates).

The invention discloses a preparation method of a flaky nanometer molybdenum disulfide material. The preparation method comprises the steps of dispersing a raw material, namely molybdenum disulfide with a lamellar crystal structure, into a mixed solution of nitric acid and hydrochloric acid; carrying out liquid phase separation by using a heating or ultrasound method; and reacting to obtain the flaky nanometer molybdenum disulfide material. The invention also discloses a nanometer composite metal anticorrosive coating material and a preparation method thereof. The nanometer composite metal anticorrosive coating material is prepared by compounding flaky nanometer molybdenum disulfide and nanometer silicon dioxide sol. The preparation method disclosed by the invention is simple; the raw material is easily available; the flaky nanometer molybdenum disulfide material and the nanometer composite metal anticorrosive coating material are widely applied to the antirust treatment and performance improvement of metal materials; the service life of metal is prolonged; and the energy consumption is reduced.

The invention discloses a laser-electromagnetic ultrasound method and a laser-electromagnetic ultrasound probe device for non-destructive testing of a thermal barrier coating. The method for detecting local tiny interface crack and peeling between a ceramic coating and a metal bonding layer of a thermal barrier coating material system comprises the following steps of: for the non-destructive testing of the tiny crack and peeling in the thermal barrier coating structure, adopting at least one permanent magnet or an electric magnet for providing a static magnetic field, excitation coils capable of generating an alternating magnetic field, and a laser interferometer head for receiving an ultrasonic wave signal on the surface of a test piece; and during testing, making a probe close to the surface of the thermal barrier coating material, and directly exciting ultrasonic wave in the metal bonding layer and an alloy base below the ceramic coating of the thermal barrier coating system through an eddy excitation coil and the permanent magnet. Finally, the laser interferometer head connected with a laser interferometer is used for measuring the transmission ultrasonic wave signal from the interior of the metal bonding layer and the alloy base to the ceramic layer through the interface of the ceramic layer and the bonding layer so as to detect the interface crack or peeling between the ceramic layer and the bonding layer.

The invention discloses a stable nano graphene oxide under physiological condition, which is characterized in that: based on the prior finished product, the nano graphene oxide also contains two types of hydrophilic groups, namely carboxylic acid functional group and sulfonic acid functional group, by further chemically modification. Firstly, crystalline flake graphite is oxidized by adopting a Hummer method; secondly, graphene oxide is peeled off by an ultrasonic method; thirdly, the graphene oxide is fragmented into nano size by an ultrasonic probe method; and finally, carboxylic acid modification is performed on the nanoscale graphene oxide by an immersion ultrasound method, carboxyl functional groups are introduced, benzene sulfonation modification is performed on the graphene oxide, and sulfonic acid groups are introduced on the edge of the graphene oxide. The nano graphene oxide can improve the stability of graphene oxide in saline solution or cell culture media, and a powerful guarantee for the medicinal application of nano graphene oxide under physiological condition is provided. Compared with the polyethylene glycol modification method, the method has the advantages of reducing manufacture cost and facilitating mass production.

Methods and apparatus for medical imaging using diffusive optical tomography and fluorescent diffusive optical tomography are disclosed. In one embodiment, a method for medical imaging comprises, scanning a tissue volume with near-infrared light to obtain structural parameters, wherein the tissue volume includes a biological entity, scanning the tissue volume with near-infrared light to obtain optical and fluorescence measurements of the scanned volume, segmenting the scanned volume into a first region and a second region, and reconstructing an optical image and a fluorescence image of at least a portion of the scanned volume from the structural parameters and the optical and fluorescence measurements. In another embodiment an apparatus for medical imaging is disclosed.

The invention discloses a conductive polymer-coated silicon-based negative electrode material and a preparation method thereof. The method comprises the following steps of adding sodium alginate to a water solution, and then stirring and dissolving the sodium alginate; adding a conductive polymer monomer to the completely dissolved sodium alginate solution and stirring evenly; adding taken nanometer silicon to a mixed solution and mixing evenly through an ultrasound method to obtain a silicon dispersion liquid; adding an initiator to the silicon dispersion liquid and carrying out polymerization reaction on the conductive polymer monomer to obtain the conductive polymer-coated silicon-based negative electrode material; and carrying out washing and drying and finishing preparation of a final product. A three-dimensional mesh structure is built by the conductive polymer, so that the conductive polymer-coated silicon-based negative electrode material has conductivity and also provides a certain accommodation space for volume expansion of the silicon; and the silicon is embedded into the mesh structure, so that the volume effect of the silicon is effectively relieved. Furthermore, the hydroxyl-containing sodium alginate is introduced, so that the structure stability of the overall silicon-based negative electrode material is strengthened.

An ultrasound method and medical devices using same provide for various techniques of sampling blood flow velocity, e.g., at several sampling rates. To minimize the energy required for ultrasound monitoring, pulsed Doppler signal packages provided by a pulsed ultrasound circuit are switched in such a way that the repetition rate is the lowest possible and yet sufficiently high to be able to record the blood flow velocity within the heart. For example, an ultrasound circuit may be activated only within a part of the cardiac cycle designated as the Doppler Measurement Interval (DMI); the ultrasound circuit may be switched between an on state and an off state during the DMI; and / or the ultrasound circuit may also be switched on and off in different sampling modes: detection mode and measurement mode (e.g., using different sampling rates).

A method and apparatus for acquiring multi-line acquisition ultrasound data. Ultrasound signals are transmitted into an area of interest. Echo signals are acquired and analyzed to produce a first data stream associated with a first receive beam. The first data stream is decimated by removing at least two consecutive data samples therefrom, while passing at least two consecutive data samples to form a first decimated data stream. Using this decimation pattern, a bandwidth of one-half to three-quarters of the data sampling rate after decimation may be achieved.

The invention discloses a method for preparing a nano-particle dispersed ultrafine grain metal matrix nano composite. The method comprises the following steps: adding nano-particles into a molten metal or an alloy solution through conventional stirring to enable the nano-particles to be dispersed in the whole melt; meanwhile, adopting the high-intensity ultrasonic method to disperse locally clustered or segregated nano-particles to produce nano-particle reinforced metal matrix composite ingots; conducting multi-pass repeated compression severe plastic deformation on the produced nano-particle reinforced metal matrix composite to thin the matrix structure and uniformly disperse the locally clustered and segregated nano-particles, and meanwhile, preventing casting defects to finally obtain the nano-particle dispersed ultrafine grain metal matrix nano composite of which the reinforcement phase is distributed in a uniformly dispersed manner and the matrix structure is thinned. The invention solves the problem of clustering or local segregation of nano-particles in the nano-particle reinforced metal matrix composite, the matrix ultrafine grain structure is controlled while the nano reinforcement phase is distributed in a dispersed manner, and the material toughness is improved.

Methods and systems for assessing the effects of therapy on a patient include obtaining baseline and treatment ultrasound scans of a treatment area of a patient where the treatment ultrasound scans are taken subsequent to the baseline scan and at various times during a course of radiotherapy treatment sessions. The baseline and treatment ultrasounds are compared, and as a result a damage map representing cell death within the treatment area can be constructed.

An ultrasonic low-noise analog beamformer for Doppler acquisition achieves high sensitivity by translating the frequency of the ultrasound echoes to an intermediate frequency, which is well above of the 1 / f corner. This is accomplished by beamforming the downconverted RF signals instead of using their baseband representation. The baseband conversion, succeeding the beamformation, also incorporates the steps of clutter filtering and anti-aliasing. The invention is particularly suitable for low-voltage process technologies that support broadband applications.

An ultrasonic low-noise analog beamformer for Doppler acquisition achieves high sensitivity by translating the frequency of the ultrasound echoes to an intermediate frequency, which is well above of the 1 / f corner. This is accomplished by beamforming the downconverted RF signals instead of using their baseband representation. The baseband conversion, succeeding the beamformation, also incorporates the steps of clutter filtering and anti-aliasing. The invention is particularly suitable for low-voltage process technologies that support broadband applications.

A method and apparatus for acquiring multi-line acquisition ultrasound data. Ultrasound signals are transmitted into an area of interest. Echo signals are acquired and analyzed to produce a first data stream associated with a first receive beam. The first data stream is decimated by removing at least two consecutive data samples therefrom, while passing at least two consecutive data samples to form a first decimated data stream. Using this decimation pattern, a bandwidth of one-half to three-quarters of the data sampling rate after decimation may be achieved.

The invention discloses a preparation method of an N-containing graphdiyne material, wherein the preparation method comprises the steps: by using an N-containing six-membered heterocyclic compound anda metal alkyne compound as raw materials and ethanol as a solvent, carrying out ultrasonic reaction under the condition of ultrasonic frequency of 50-55 kHz, separating after the reaction is finished, washing a collected solid, and drying to obtain the N-containing graphdiyne material. The N-containing graphdiyne material is prepared by adopting an ultrasonic method, taking the N-containing six-membered heterocyclic compound and a metal alkyne compound as raw materials and taking ethanol as a solvent, nitrogen elements in the prepared N-containing graphdiyne material are distributed orderly,and the whole preparation method is simple to operate, mild in condition, green, environment-friendly and relatively low in equipment requirement; besides, experiments show that the N-containing graphdiyne material prepared by the method has excellent hydrogen evolution performance and energy storage performance, effectively promotes the application of the graphdiyne material in the fields of hydrogen evolution materials, supercapacitors, lithium ion battery negative electrode materials and the like, and has a wide industrial application prospect.

The invention discloses a preparation method and application of a nitrogen-doped peel based porous carbon material. According to the method, waste peel is used as biomass raw materials; through an ultrasound method, the waste peel and a nitrogen source are pretreated; at low-temperature, the materials are pre-carbonized into nitrogen-doped peel based carbon; then, potassium bicarbonate is used asan activating agent for activation at high temperature; finally, through treatments of acid washing, water washing, drying and the like, the preparation of a nitrogen-doped peel based porous carbon super capacitor electrode material with high specific surface area, good pore diameter distribution and certain nitrogen content is realized. The prepared super capacitor material has excellent electrochemical performance which is shown in aspects of high specific capacitance, high energy density, good circulation stability and the like. In addition, the method does not relate to the use of strong basic or strong acidic or toxic activating agents; the preparation method is low in cost and achieves the environment-friendly effects.

The invention discloses a one-step manufacturing method of three-dimensional graphene / graphite-phase carbonized nitrogen based on a hydrothermal method. Through using a ultrasonic method, graphene oxide (GO) and graphite-phase carbonized nitrogen (g-C3N4) are mixed, and then hydrothermal reaction is performed. During a reaction process, the GO is restored and simultaneously the GO and the g-C3N4 are assembled into a hydrogel column. Then, through freeze drying, three-dimensional graphene / g-C3N4 is acquired. In the invention, operation is simple and is green and environmental protection; cost is low; a technology condition is easy to realize; a manufactured three-dimensional graphene / g-C3N4 composite material possesses a pore structure with a high orientation degree; in addition, the composite material possesses a high specific capacitance; and a latent application value is possessed on an aspect of a super capacitor.

Methods and apparatus for measuring heat flux in a material are disclosed. A disclosed example method involves emitting an acoustic signal into the material and determining a first propagation time associated with the propagation of the acoustic signal through the material. A first heat flux value indicative of a first heat flux of the material is then determined based on the first propagation time.

The invention discloses a solvent-extraction-and-fluorescence determination method of microalgae lipid content, and belongs to the technical field of microalgae crude lipid determination. The solvent-extraction-and-fluorescence determination method of the microalgae lipid content solves the problems of a fluorimetry in the prior art that dyeing with direct use of Nile red fluorescent staining is halfway and disturbance of microalgae body chlorophyll fluorescence peaks and the like occur when an ultrasound method or a dimethyl sulfoxide (DMSO)-processing-Nile-red-dyeing fluorescence determination method is in use. The solvent-extraction-and-fluorescence determination method of microalgae lipid content comprises the following steps of preparing a standard curve by using microalgae to prepare standard microalgae liquid, extracting microalgae lipid and determining content of the microalgae lipid by using fluorescence. Due to the fact that in a determination process, operation steps are free from evaporation organics, and pollution to the environment is little. The solvent-extraction-and-fluorescence determination method of the microalgae lipid content has the advantages that the solvent-extraction-and-fluorescence determination method of the microalgae lipid content is rapid, simple, effective and sensitive, and determination results are free from influence of retention periods of microalgae samples.