86 results about "Salicin" patented technology

A topical analgesic for sensitive skin for providing a fast-acting and deeply penetrating topical analgesic that does not irritate sensitive skin teaching a chemical composition consisting of one or more herbs containing the properties of an analgesic such as those selected from a group of herbs containing methyl salicylate, salicin, or menthol, including birch bark, wintergreen, willow bark meadowsweet and peppermint or any other herbs with analgesic properties, such as but not limited to, lavender, Arnica Montana, passion flower, calendula, chamomile; a transdermal agent, such as Arnica Montana; one or more herbs containing the properties of an anti-inflammatory, such as lavender or birch bark; Myrrh; and a base to hold the ingredients together and make it applicable to skin. The topical analgesic may also include a natural preservative to increase product stability and shelf life and one or more essential oils for added pain relief using olfactory senses.

The process of extracting and separating salicin from fresh branch of red willow material includes crushing the material, mixing with lime via stirring, letting stand for 30 min, thrice ethanol extraction, recovering ethanol to obtain dilute extractum, diluting with water and filtering to obtain filtrate, elution in macroporous resin, merging effluent and water washing liquid, concentration to crystallize, re-crystallize, suction filtering and vacuum drying. The present invention has simple technological process, low cost, high yield and less 'three waste', and is suitable for industrial production.

The invention relates to a kind of salicin and its manufacturing technology, which belongs to biology extraction field. The technology solution of the invention includes the steps in turn as follows: 1) Stock preparation: shatter with leaf into carven stock; 2) Hydrolysis and extraction: add basic matter into raw material for hydrolysis, and then extract with extraction agent in order to remove residue; 3) Concentration: get the semi-manufactured product containing salicin extractive material. The advantages of this industrial art can be described as follows: 1. acquirable raw material; 2. forthright industrial art; 3. high yield: the yield of the product is high, and according to production verification, the purity of salicin with refining step can achieve up to more than or equal to 99%; 4. low cost: the production of 1 kilogram with 95%n purity only sales a little more than upsi 3000.

Described is a composition for the prevention and treatment of symptoms associated with ethyl alcohol consumption. The composition comprises silymarin, salicin, at least one B vitamin, magnesium, molybdenum and manganese. Treatment of symptoms associated with the consumption of ethyl alcohol involves ingesting the described composition prior to, during, or after the consumption of the alcohol.

The invention relates to a method for extracting salicin from white willow bark. According to the method, a salicin-rich product is obtained through a process including sterilization, infiltration, enzymolysis extraction, separation and drying. The method creatively adopts the process in which enzyme deactivation and salt solution soaking are performed before enzymolysis, the kind of enzyme in enzymolysis reaction is determined by system screening, and a white willow bark extract containing more than 95 percent of salicin is obtained through twice column chromatography separation and microwave drying. Quicklime is not needed to be used in the whole method, all materials used in the method are conventional materials, the cost is low, the yield is high, a solvent can be used repeatedly, environmental pollution is reduced, and industrialization is facilitated.

The invention belongs to the technical field of extraction and separation of active ingredients from a plant, and specifically relates to a method for purifying salicin in white willow bark by using an ultrasonic extraction-macroporous resin combined technology. The method is characterized in that: the purpose of the method is to overcome disadvantages of relatively low extraction rate, low extraction purity and the like of the conventional technology, and to provide a method for purifying salicin in white willow bark by using an ultrasonic extraction-macroporous resin combined technology. The method has the following advantages that: the ultrasonic extraction is adopted, such that advantages of low extraction temperature, high efficiency, short extraction time, and the like are provided, the salicin extraction rate is substantially improved, and the extraction time is shortened; the macroporous resin is adopted to adsorb the salicin, such that the good adsorption effect on the salicin is provided; and an ethanol water solution is adopted to extract salicin, such that the dissolving effect is good, the salicin consumption is reduced, and the yield is increased.

This invention discloses drug-delivery compositions, methods of making prodrugs, and methods of drug delivery using a self-assembled gelator. The backbone of the gelator can contain a drug or prodrug, such as acetaminophen or salicin. Additional drugs or agents can be encapsulated in the gelator. Enzymatic or hydrolytic cleavage can be used to release the drugs.

Described is a composition for the prevention and treatment of symptoms associated with ethyl alcohol consumption. The composition comprises silymarin, salicin, at least one B vitamin, magnesium, molybdenum and manganese. Treatment of symptoms associated with the consumption of ethyl alcohol involves ingesting the described composition prior to, during, or after the consumption of the alcohol.

The invention belongs to the technical field of chemical engineering and particularly relates to an extract prepared by using willow barks or willow branches as raw materials, and a method for preparing high-purity salicin, aiming at providing a method for extracting high-content salicin from the willow barks or the willow branches. The method comprises the following steps of: (A) taking the willow barks or the willow branches as the raw materials and carrying out extraction by using an aqueous or alcoholic solution, (B) filtering an extracted solution, (C) carrying out resin adsorption separation on a filtrate, (D) decolorizing, and (E) crystallizing and is characterized in that: an ultrafiltration manner is adopted to filter when the filtration is carried out in the step (B), the extracted solution is firstly filtered by using a 100-500 kD ultrafiltration membrane and then is filtered by using a 5-10 kD ultrafiltration membrane, and the average membrane fluxes are respectively controlled at 100-190 LMH and 20-24 LMH. According to the method provided by the invention, the steps of extraction and ultrafiltration are adopted in coordination with the processes of adsorption, decolorization, crystallization and the like, the content of the obtained salicin can reach 99.0%, the yield is high, the cost is low, and the water and a small amount of alcohol which are used in production can be recycled, so that the cost is lowered, the pollution to the environment caused by organic solvents is reduced, and the implementation of industrialization is facilitated.

The invention belongs to the technical field of animal husbandry, and is a method of detecting the activity of cellulose in tumor gastric juice of ruminant. Testing subjects can be three fistula cows, and tumor gastric juice can be sampled 2h after the early feeding to be used for conducting the external detection of the activity of cellulose. Cellulose mainly contains: (1) microcrystalline cellulose, (2) carboxymethyl cellulose and (3) salicin.

A method for preparing crystalline salicin from salicaceae plants takes branches or leaves of salicaceae plants as raw materials and comprises the following steps: pulverizing the raw materials and adding quicklime; extracting the mixture by using water as the solvent; filtering the extract by a membrane device; concentrating the membrane permeate liquid to obtain a specific gravity of 1.10-1.20; allowing to stand for white crystal precipitation; washing by water or ethanol; drying to obtain crystalline salicin. Compared to the prior art, the present invention performs the extraction by using water as the solvent; achieves the advantages of low production cost, high yield, less three wastes and no environmental pollution; and is applicable to large-scale and industrial production.

The invention relates to a method for extracting active components traditional Chinese medicine, in particular a method for extracting salicin. The invention solves the problems existing in the prior art that the extract substances have many impurities and bad qualities, and the technical operation is complicated, and so on, and provides the method for extracting salicin. The method comprises extraction and purification, wherein the extraction process comprises ultrasonic wave effect and an enzymolysis process. The method disclosed by the invention has advantages of convenient operation, high product recovery rate and good quality. The method can also achieve the industrialized production requirements, and is suitable for popularization and application.

Compositions comprising chromium complexes such as chromium picolinate or chromium nicotinate are administered to a subject presenting with Polycystic Ovary Syndrome. The compositions may further comprise at least one of a chelating agent, cyclooxygenase inhibitor, a mucolytic, and / or a salicin-containing herb.

The invention provides a preparation method for extracting salicin from bamboo-willow bark. The method comprises the following steps: Step 1, a raw material is dried and pulverized, wherein the bark of bamboo-willow with age more than 2 years is adopted as a raw material, and is dried and pulverized; the powder is sieved with a mesh with a size of 20-40 meshes, such that bamboo-willow park powder is prepared; the powder is dried with a continuous microwave drying method under a drying temperature of 60-95 DEG C, such that bamboo-willow park powder is obtained, wherein the particle size of the powder is 20-40 meshes. The raw material adopted by the method has the advantages of low solvent consumption and low cost. The extraction separation method is simple to operate, and has low equipment requirement, such that the method is suitable for large-scale popularization. In a product 1, salicin content is stabilized at 80-85%, and a yield is approximately 2.0%.

The invention discloses a method for preparing a medicinal raw material salicin from white willow branch bark. The method comprises the following steps of: grinding the white willow branch bark; adding 20 to 30 weight percent of quicklime; mixing uniformly; conveying the mixture into an extracting tank; performing reflux extraction for three times by using methanol, wherein each time lasts for 1.5 hours; concentrating the extracting solution under reduced pressure until no alcohol exists; adding water in an amount which is 3 to 6 times that of concentrated solution into the concentrated solution; adjusting the pH value to be 9 to 13; standing for 24 hours; concentrating supernatant liquor under reduced pressure until the specific gravity D is equal to 1.10 to 1.13; adding 95 percent methanol in an amount which is 5 times that of concentrated solution into the concentrated solution; standing for 24 hours; performing alcohol precipitation; concentrating supernatant liquor under reduced pressure until the specific gravity D is equal to 1.10 to 1.13; and drying the concentrated solution by spraying powder to obtain the salicin with the content of 25 percent. In the method, the step of performing alcohol precipitation is added; the salicin with the content of 25 percent is directly separated; and the extraction ratio is increased from 4.3 percent to 9 percent. The method is simple in process and suitable for different scales of production, and the cost is obviously reduced.

The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery, deterioration of proper joint function including joint mobility, the reduction or inhibition of metabolic activity of chondrocytes, the activity of enzymes that degrade cartilage, said method comprising administering effective amounts of Boswellia Serrata, effective amounts of freeze dried green lipped mussle, effective amounts of white willow bark extract containing salicin, effective amounts of angelica root, effective amounts of glucosamine and salts thereof, effective amounts of chondroitin and salts thereof and effective amounts of omega 3 fatty acids.

This invention discloses drug-delivery compositions, methods of making prodrugs, and methods of drug delivery using a self-assembled gelator. The backbone of the gelator can contain a drug or prodrug, such as acetaminophen or salicin. Additional drugs or agents can be encapsulated in the gelator. Enzymatic or hydrolytic cleavage can be used to release the drugs.

The invention provides a method for distinguishing bee glue and poplar glue. In the method, HPLC (High Performance Liquid Chromatography) is used for measuring salicin to judge the authenticity of the bee glue so as to control the quality of the bee glue, and the measurement of the salicin by using the HPLC has the advantages of high sensitivity, strong repeatability, and the like. The method used for judging the authenticity of the bee glue has the advantages of high accuracy, high sensitivity, short time and low cost. The method proposes the standard product i.e. the salicin for the first time, thus even if an operation is carried out in the presence of different conditions, the bee glue and the poplar glue. can be accurately and qualitatively distinguished according to the peak time and the ultraviolet absorption of the salicin. The method has good separation effect and high sensitivity and strong feasibility and can be used for distinguishing the bee glue in which more than 10 percent of the poplar glue doped.

The invention discloses a process for extracting salicin from populus euphratica fallen leaves. The process is characterized by comprising the following steps: adding calcium oxide into populus euphratica fallen leaf shreds, and adding water for decomposing; extracting the solution twice at the temperature of 30 DEG C, collecting filtrate, and combining the filtrate; adjusting the pH value to 10.0-12.5, allowing the solution to stand, and collecting the filtrate; concentrating the filtrate, adding a clarifying agent or an adsorbent for decolorizing while stirring at the temperature of 70 DEG C, and colleting the filtrate; adjusting the pH value to 3.0-5.0 at a normal temperature, allowing the solution to stand, and collecting the filtrate; adding ammonium water or ammonia gas into the filtrate for adjusting the pH value to 7.0-9.0, concentrating the filtrate till the specific weight is 1.2, and crystalizing the filtrate at the normal temperature in a static manner for 72 hours; and separating a crystal, drying the separated crystal at 80 DEG C, and smashing the dried crystal. The process has the beneficial effects that water with low environmental pollution is taken as an extraction solvent, so that the production cost and the workshop requirement are lowered; ash is removed by adopting sulfuric acid or sulfate, and the crystal is obtained through the crystallizing step, so that the purity of a final product is increased, and can be over 65 percent in general; and natural fallen leaves of populus euphratica in autumn are taken as raw materials, so that damage to vegetation is prevented.

The invention discloses the method of improving the content of the salicin in the plant and the appropriative carrier. The carrier is the plant expressing carrier containing the separating offset acid composing enzyme gene and the separating offset acid-the pyruvic splitting dividing enzyme gene. The method uses the salicin composing approach and guides the different ICS gene and the IPL gene into the plant. The invention guides the said carrier into the plant group or the cell to gain the turning gene plant of the content of the salicin improved. The transferring gene test indicates that the dissociating state SA content in the transferring gene rice is mostly nine times than the wildness type. The method of the invention and the appropriative carrier can improve the content of the salicin in the plant greatly and provides the new method of amending the plant breed and improving the crop.

The invention belongs to the technical field of chemical engineering and particularly relates to an extract prepared by using willow barks or willow branches as raw materials, and a method for preparing high-purity salicin, aiming at providing a method for extracting high-content salicin from the willow barks or the willow branches. The method comprises the following steps of: (A) taking the willow barks or the willow branches as the raw materials and carrying out extraction by using an aqueous or alcoholic solution, (B) filtering an extracted solution, (C) carrying out resin adsorption separation on a filtrate, (D) decolorizing, and (E) crystallizing and is characterized in that: an ultrafiltration manner is adopted to filter when the filtration is carried out in the step (B), the extracted solution is firstly filtered by using a 100-500 kD ultrafiltration membrane and then is filtered by using a 5-10 kD ultrafiltration membrane, and the average membrane fluxes are respectively controlled at 100-190 LMH and 20-24 LMH. According to the method provided by the invention, the steps of extraction and ultrafiltration are adopted in coordination with the processes of adsorption, decolorization, crystallization and the like, the content of the obtained salicin can reach 99.0%, the yield is high, the cost is low, and the water and a small amount of alcohol which are used in production can be recycled, so that the cost is lowered, the pollution to the environment caused by organic solvents is reduced, and the implementation of industrialization is facilitated.

The invention discloses a preparation method of herbicide anilofos with water as a solvent. A proper amount of a phase transfer catalyst is added during a reaction procedure; condensation and crystallization are completed in a single step; when the reaction is finished, a reaction liquid is cooled; anilofos crystals are directly precipitated in water; the crystals are filtered and washed, such that anilofos products are obtained. According to the invention, no organic solvent or heat precipitation procedure is adopted during the reaction procedure. Therefore, a potential danger that the product is easy to be decomposed under heat is avoided from the source, and product yield and quality are improved. The preparation method of herbicide anilofos provided by the invention has advantages of easy operation, environment protection, high product yield and good product quality. The method is green, safe, reliable, and is suitable for industrialized productions.

The invention belongs to the technical field of extraction and separation of active ingredients from a plant, and specifically relates to a method for purifying salicin in white willow bark by using an ultrasonic extraction-macroporous resin combined technology. The method is characterized in that: the purpose of the method is to overcome disadvantages of relatively low extraction rate, low extraction purity and the like of the conventional technology, and to provide a method for purifying salicin in white willow bark by using an ultrasonic extraction-macroporous resin combined technology. The method has the following advantages that: the ultrasonic extraction is adopted, such that advantages of low extraction temperature, high efficiency, short extraction time, and the like are provided, the salicin extraction rate is substantially improved, and the extraction time is shortened; the macroporous resin is adopted to adsorb the salicin, such that the good adsorption effect on the salicin is provided; and an ethanol water solution is adopted to extract salicin, such that the dissolving effect is good, the salicin consumption is reduced, and the yield is increased.

A composition for alleviating hangover symptoms in a subject in need thereof. The composition comprises dihydromyricetin, N-Acetyl Cysteine, taurine, salicin, niacin, vitamin B6, selenium, manganese and prickly pear powder. The composition can be formulated as pills or capsules. The dihydromyricetin component may be coated with soy lecithin to maximize absorption. The composition includes a first composition and a separate second composition. The composition is administered as a first pill or capsule comprising the first composition prior to alcohol consumption and a second pill comprising the first composition taken after alcohol consumption.

Provided is comprehensive exploration and utilization of active ingredients in branches and leaves of weeping willows. The technology of the comprehensive exploration and utilization of the active ingredients in the branches and the leaves of the weeping willows mainly comprises the following steps: (1) abstracting and concentrating; (2) alcohol precipitating and concentrating; (3) extracting; (4) preparing catechol; (5) preparing salicylic acid; and (6) separating tannin and saligenin. The technology of the comprehensive exploration and utilization of the active ingredients in the branches and the leaves of the weeping willows abstracts the saligenin, at the same time comprehensively, efficiently, and synchronously abstracts the other active ingredients of the catechol, the salicylic acid and the tannin and the like in the weeping willows.

The invention discloses a preparation process of a salicin comparison product. The preparation process includes following steps of extracting salicin from poplar flowers; preliminarily separating the salicin by using macroporous resins; extracting n-butanol; separating and purifying the salicin by means of a normal phase silica gel method; and recrystallizing the salicin. Compared with preparation processes in prior art, the preparation process of the salicin comparison product can well meet requirements of traditional Chinese medicine standard products.

The invention discloses a method for cultivating eggplant trees by means of a radical bud induced grafting technology. The method includes the steps of seedbed management, eggplant seedling stage cultivation, transplanting and field planting, induced germination, radical bud grafting and eggplant tree cultivating. The radical bud grafting includes the steps that approach grafting is performed on a radical bud branch and a side branch; during approach grafting, the side branch is cut in from bottom to top at the angle of 40-55 degrees, the cut-in depth is 1 / 3-1 / 2 of the diameter of the side branch, and a notch is in the shape of a wedge; the upper portion of the radical bud branch is removed, and the shape of a radical bud notch is matched with the side branch notch. The induced germination includes the steps that adopted plant growth regulator comprises buddleoglucoside, gibberellin, salicin, L-epicatechol, magnolol, glycyrrhizin, 6-benzyladenine and water. The method is adopted for cultivating eggplant trees, the survival rate is high, the crown breadth is large, the plant height is large, the fruit-set percentage is high, and the yield per plant is high.

The invention relates to the technical field of processing of tranquilizing incenses, and in particular to a camellia peel tranquilizing incense and a preparation method thereof. The tranquilizing incense provided by the invention is prepared from the following raw materials: a camellia peel extract, a lavender extract, a common bombax flower extract, a willow leaf extract, gelatin and glycerol; in the formula, the camellia peel extract can take effects of tranquilizing, sterilizing and promoting sleep when the incense is burned; the lavender extract, the common bombax flower extract and the willow leaf extract can effectively improve fragrance of the tranquilizing incense, so that a more effective function of promoting sleep is achieved; and the willow leaf extract, besides a function of improving sleep on the basis of fragrance, can also take a certain effect of expelling insects by virtue of salicin contained in the willow leaf extract. According to the preparation method, a camellia fruit extract is also extracted by virtue of a supercritical CO2 extraction method, an organic matter solvent extraction method and a gel separation method; and camellia fruits are processed through microwave and ultrasonic pre-treatment, so that effective cell disruption is implemented, and separation efficiency of essential oil, polyphenol and flavone is effectively guaranteed.

The invention discloses a high-yield extraction method of salicin in branches and leaves of white willows. The method includes the steps of: crushing, pre-treatment, extraction, concentration, adsorption separation, decoloration, concentration crystallization, etc. In the method, before extraction, the branches and leaves of white willows are treated through ultraviolet irradiation, gas flow pulverization, liquid nitrogen freezing and microwave de-freezing, so that the cell wall structure of the branches and leaves of white willows is effectively damaged while active components in the cells are not damaged, thus remaining the nutrients as most as possible and bringing convenience to dissolution-out of the salicin in subsequent extraction step. In the extraction method, through treatment successively carried out with low-frequency ultrasonic wave, high-frequency ultrasonic wave and medium-frequency ultrasonic wave, cell tissue of the branches and leaves of white willows is further subjected to wall disruption or deformation, so that the active components are extracted more completely and extraction rate of the salicin is greatly increased; and then a filter residue of the branches and leaves of white willows is processed in a high-voltage pulse electric field, so that dissolution-out of the salicin in the filter residue of the branches and leaves of white willows is further promoted, thereby greatly increasing the yield of the salicin.

The invention relates to a preparation method of a leaching liquid for repairing heavy metal polluted soil; the method comprises the steps: putting dioctyl sebacate, 4-(2,6,6-trimethyl-2-cyclooctene-1-yl)-3-butene-2-one, 1,4-dimethyl piperazine, 2-pyridinemethanol, oleanolic aldehyde, salicin, 4-isoquinolinamine and alkyl polyoxyethylene ether acetate into a flask provided with a stirrer, a thermometer and a reflux condensing tube, adding deionized water and polycarboxylic acid salt, heating up to 850 DEG C, introducing nitrogen for protection, and stirring for 45-75 min; and then slowly dropwise adding ammonium citrate, after carrying out heat preservation for 2 h, adding sodium alginate, sodium ethoxide, polyoxypropylene diol and fatty alcohol polyoxyethylene ether, then carrying out a reaction for 4-7 h, cooling to room temperature, and thus obtaining the leaching liquid for repairing the heavy metal polluted soil. The leaching liquid provided by the invention can effectively remove organic pollutants in the soil while repairing the heavy metal contaminated soil, thereby greatly reducing the soil repairing cost.