Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation process of salicin comparison product

A preparation process, a technology for crude salicin, applied in the preparation of sugar derivatives, sugar derivatives, sugar derivatives and other directions

Inactive Publication Date: 2013-01-09
CHENGDU QIANKUN VETERINARY PHARMA
View PDF3 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are certain defects in the preparation process of the salicin reference substance in the prior art, which needs to be improved to better meet the requirements of the traditional Chinese medicine standard substance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation process of salicin comparison product
  • Preparation process of salicin comparison product
  • Preparation process of salicin comparison product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0020] In order for those skilled in the art to better understand the technical solutions provided by the present invention, the following will be described in conjunction with specific embodiments.

[0021] The preparation process of the salicin reference substance provided by the embodiments of the present invention comprises the following steps:

[0022] (1) Extraction of salicin from poplar flowers: Take 4kg of poplar flowers, cut them into pieces, add 15 times the amount of water to decoct and extract twice, each time for 1.5h, combine the two liquids, filter, let the filtrate stand overnight, and take the upper layer to clarify the extract A , (about 95L), spare;

[0023] (2) Preliminary separation of salicin by macroporous resin, including the following steps (21) and (22):

[0024] (21) Pretreatment of macroporous resin: take macroporous resin D-1015kg, add acetone 8000-10000ml, stir, soak for 12 hours, put into chromatography column, drain acetone, rinse with distill...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
melting pointaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation process of a salicin comparison product. The preparation process includes following steps of extracting salicin from poplar flowers; preliminarily separating the salicin by using macroporous resins; extracting n-butanol; separating and purifying the salicin by means of a normal phase silica gel method; and recrystallizing the salicin. Compared with preparation processes in prior art, the preparation process of the salicin comparison product can well meet requirements of traditional Chinese medicine standard products.

Description

technical field [0001] The invention relates to the field of preparation of a reference substance, in particular to a preparation process of a salicin reference substance. Background technique [0002] Salicin is white crystal; taste bitter; melting point 199~202℃, specific optical rotation [α] 厍-45.6° (0.6g / 100cm3 absolute ethanol); soluble in water, easily soluble in boiling water, insoluble Soluble in ethanol (1:90), insoluble in ether or chloroform, but soluble in alkali solution, pyridine or glacial acetic acid, its aqueous solution has a neutral reaction, there is no free phenolic hydroxyl group in the molecule, and it belongs to phenolic glycoside compounds; Or hydrolyzed by amygdalin to produce glucose and salicyl alcohol. The molecular formula of salicyl alcohol is C7H8O2; it is orthorhombic colorless needle crystal; the melting point is 86-87°C; it sublimes when heated to 100°C; it is soluble in water and benzene, easily soluble in ethanol, ether, and chloroform; ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07H15/203C07H1/08
Inventor 房春林吴学渊李超杨海涵李犹平
Owner CHENGDU QIANKUN VETERINARY PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com