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46 results about "Molecular stability" patented technology
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Protein Stability (Molecular Biology) Protein stability involves the ability of the native, folded protein structure to withstand the disruptive, denaturing influence of the external environment, its resistance to unfolding (see Proteins).
Bivalent IgY antibody constructs for diagnostic and therapeutic applications
InactiveUS20070141049A1Improve the immunityIncrease contentImmunoglobulins against virusesAntibody ingredientsHeavy chainMammal
This invention relates to the field of recombinant antibody technology. It provides novel recombinant IgY antibody constructs for diagnostic and therapeutical applications. The bivalent antibody constructs display a heterotetrameric or homodimeric format stabilized by disulfide bonds. The constant heavy chain domains CH2-CH4 are partly or completely of avian origin, whereas the VH, VL, CL, and CH1 domains as well as the hinge region may be of avian origin or derived from any other species. The invention allows to combine the advantages of IgY antibodies with those of established mammalian monoclonal antibodies. IgY antibody constructs comprising nonglycosylated IgY constant heavy chain domains allow to reduce unwanted interactions with C-type lectins, e.g., in human sera. Furthermore, chimeric IgY antibody containing mammalian VH, VL, CL, and CH1 domains as well as a mammalian hinge region provide a higher molecular stability than IgY antibodies in acidic conditions and, thereby, are especially suited for peroral therapeutic applications.
Owner:PLS DESIGN
Mixed absorbing agent for catching or separating carbon dioxide
The invention relates to a mixed absorbing agent for catching or separating carbon dioxide from gas mixture, which mainly comprises the components by weight percent: 10-50wt% of 3-dimethyl amino-1-propyl alcohol, 5-10wt% of primary amine and / or secondary amine and balance water. The absorbing agent has high solubility for low-pressure carbon dioxide, good desorbing effect, lower reaction heat of absorption reaction and lower energy consumption for catching or separating the carbon dioxide; and as the 3-dimethyl amino-1-propyl alcohol is a tertiary amine and has high boiling point and better molecular stability than primary amine and secondary amine, so that the mixed absorbing agent can greatly reduce the degradation consumption of solvent in the using process, has good catching effect, and can be used for catching or separating the carbon dioxide in various gas mixtures such as flue gas, refinery gas, natural gas, synthesis gas, shift gas, hydrogen preparation gas and the like.
Owner:TSINGHUA UNIV
Polysubstituted silacyclohexadiene and synthetic method thereof
InactiveCN101284845AHigh molecular stabilityHigh isolation yieldGroup 4/14 element organic compoundsEnd-groupPhosphate
The invention provides polysubstituted silicon heterocyclic hexadiene as shown in formula I, wherein R<1> and R<2> are identical or different and represent alkyl or aryl; R<3> represents hydrogen, aldehyde group, ketone group, ester group and phosphate group; R<4> represents alkyl and aryl; R<5> represents hydrogen, alkyl, alkenyl and aryl; and R<6> represents alkyl and aryl. The compound which has high molecular stability is an important precursor of organic conducting material and organic photoelectric material. The invention adopts the insertion ring-enlargement reaction between end group alkyne and silicon heterocyclic butane under the catalysis of palladium to make the polysubstituted silicon heterocyclic hexadiene at high yield. The method, being scientific and reasonable, has easily obtained raw material, wide application range, high separation yield and simple experimental equipment and operation, and is convenient for industrial production.
Owner:PEKING UNIV
Absorption solvent used for catching or separating carbon dioxide
ActiveCN101637689AImprove solubilityImprove the desorption effectProductsCarbon compoundsSolubility1-Propanol
The invention belongs to the field of chemical materials, and particularly relates to an absorption solvent which is used for collecting or separating carbon dioxide from gas mixture or liquefied gas.The solvent comprises 3-dimethylamino-1-propanol (abbreviated as DMA1P) with a content range of 10-70 wt% and other components with a total content range of 30-90 wt%, wherein, the other components comprise one or more of monoethanol amine, n-propanol amine, hydroxyethyl piperazine, water, physical solvent, inorganic salt or auxiliary agent. The solubility of carbon dioxide in 3-dimethylamino-1-propanol is high and the deabsorption effect is good; simultaneously the reaction heat of the absorption reaction is lower and the energy consumption for collecting or separating carbon dioxide is lower; meanwhile, 3-dimethylamino-1-propanol is a tertiary amine, the carbon chain is a linear chain, six-membered ring with better molecular stability can be formed through hydrogen bond, and the degradation loss of solvent in the use process can be reduced substantially.
Owner:TSINGHUA UNIV
Organic compound containing xanthene structure and application of organic compound
ActiveCN106220619ANot easy to crystallizeNot easy to gatherOrganic chemistrySolid-state devicesGlass transitionOrganic compound
The invention discloses an organic compound containing a xanthene structure and an application of the organic compound. The structural general formula of the compound is shown in the general formula (1). The compound is high in glass transition temperature and molecular stability, proper in HOMO and LUMO energy level, and relatively high in Eg. Through device structure optimization, the photoelectric property of an OLED device is improved and the service life of the OLED device is prolonged.
Owner:JIANGSU SUNERA TECH CO LTD
Mixed absorbent for gathering or separating carbon dioxide
The invention relates to a mixed absorbent for gathering or separating carbon dioxide from a gas mixture, which mainly comprises the following components in percentage by weight: 21 to 45 percent of diethylethylenediamine, 5.0 to 9.9 percent of primary amine containing one nitrogen atom and / or secondary amine containing one nitrogen atom, and the balance of water. The absorbent has high solubility and good desorption effect on low-pressure carbon dioxide, simultaneously absorbs less reaction heat, and has low energy consumption for gathering or separating the low-pressure carbon dioxide; because the diethylethylenediamine is tertiary amine and has high boiling point and better molecular stability than the primary amine and secondary amine, so the degradation loss of a solvent in the using process can be greatly reduced. The mixed absorbent can be used for gathering or separating various normal-pressure gas mixtures, such as carbon dioxide in flue gas discharged from coal fired power plants, and enterprises in the steel, cement, petrochemical engineering and other industries.
Owner:TSINGHUA UNIV
Method for the identification of ligands
The present invention relates generally to a method of identifying ligands that modulate protein-protein interactions. More particularly, the present invention relates to methods of determining agonists or antagonists of a co-regulator dependent target molecule based on the ability to modify the stability of the target molecule in a tissue-selective manner.
Owner:BONE ROGER F +3
Preparation method for organic compound by using seven-element ring as core structure and application thereof on OLED
InactiveCN109665986AImprove luminous efficiencyOrganic chemistrySolid-state devicesSimple Organic CompoundsMolecular stability
The invention relates to a preparation method for an organic compound by using a seven-element ring as a core structure and an application thereof on an OLED, and belongs to the technical field of organic photoelectric materials. The organic compound has better molecular stability. A prepared OLED device has excellent luminous efficiency, and is capable of meeting requirements of a device manufacturer well.
Owner:烟台九目化学股份有限公司
Composition for increasing fertilizer absorption and utilization rate and application thereof
InactiveCN108558507AProtect the molecular structureDry fastOrganic fertilisersUrea compound fertilisersOrganic solventMoisture absorption
The invention provides a composition for increasing fertilizer absorption and utilization rate and application thereof. The composition comprises orange essential oil, an emulsifier and an organic solvent, wherein the orange essential oil comprises, by mass percentage, 10-30% of grapefruit essential oil and 50-70% of orange peel essential oil. A method for increasing the fertilizer absorption andutilization rate includes: adding the composition into fertilizer, evenly mixing, and applying the fertilizer to crops. The composition has the advantages that the orange essential oil in the composition can increase molecular stability in humic acid, the problems of alginic acid fertilizer gas expansion and solid fertilizer moisture absorption are solved, the orange essential oil can carry fertilizer components to fast penetrate leaves to enter the bodies of plants, and the absorption and utilization rate of humic acid fertilizer, alginic acid fertilizer, amino acid fertilizer, oligosaccharide fertilizer and fish protein fertilizer can be increased.
Owner:青岛日晟源作物营养有限公司
High molecular material thermal stability tester
InactiveCN105466966AAvoid distributingFree handsMaterial heat developmentElectricityElectronic control system
The invention provides a high molecular material thermal stability tester and belongs to the field of testing of high molecular stability. The high molecular material thermal stability tester comprises a heating device, a container and an electronic control system. The heating device comprises a heating body and a vibrating table, the heating body and the vibrating table are electrically connected with the electronic control system, and the heating body is arranged on the vibrating table; the container is internally provided with a plurality of test tubes and sample grooves, the sample grooves are fixedly connected with the container, the sample grooves are provided with mesh holes, and the interiors of the sample grooves are communicated with the interior of the container through the mesh holes. According to the high molecular material thermal stability tester, the sample grooves are utilized to fix the test tubes, the test tubes are prevented from waggling in the container, both hands of an experimenter are liberated, the test tubes are heated in the sample grooves, and meanwhile the vibrating table conducts vibration continuously, so that a solution in the container and materials in the test tubes are heated uniformly, the heating effect is good, and accuracy of tested thermal stability data and the result is high.
Owner:佛山市永恒新材料实业有限公司
Acylated derivative of mogrolic acid and preparation method thereof
The invention relates to an acylated derivative of mogrolic acid. The structure of the acylated derivative is shown as a formula (I) or a formula (II), wherein R is acyl. Hydroxyl groups in molecules of several kinds of mogrolic acid (mogrolic acid A and mogrolic acid D) containing hydroxyl groups are acylated, and on the premise that the pharmacological activity of the hydroxyl groups is not changed, the molecular structure is modified, so that the solubility is improved. Besides the solubility is improved, the molecular stability of the hydroxyl acylated mogrolic acid is improved, the residence time of the hydroxyl acylated mogrolic acid in a living body can be effectively prolonged, and the bioavailability is improved. The inventor also finds that the acylated derivative of mogrolic acid provided by the invention has excellent anti-inflammatory activity, especially a maleic acid acylated derivative of mogrolic acid.
Owner:HUNAN HUACHENG BIOTECH
Anti-shrinkage modified EVA foam shoe material and preparation method thereof
InactiveCN109021375AGuaranteed stabilityReduce the value of the residual stressFootwearCross-linkFoaming agent
The invention relates to an anti-shrinkage modified EVA foam shoe material. The material comprises 40-43 parts of Formosa Plastics 7470, 5-6 parts of Formosa Plastics 7350, 6-8 pieces of Taiju 3312, 7-8 parts of Dow 3745, 10-12 an anti-shrinkage agent 203#, 1-1.5 parts of zinc oxide, 6-8 parts of an anti-wear agent, 2-3 parts of a filler, 0.3-0.5 part of an activator, 0.6-0.7 part of a cross-linking agent, 2-2.5 parts of a foaming agent and 3-4 parts of titanium dioxide. High-melting point and low-melt strength components are selected, so the product maintains molecular stability during use, the strain force required by the shrinkage deformation of the product is improved, the material has a low melt strength when the melting point of the material is reached in the production process of the product, the resistance to volume expansion is reduced, and the residual stress of the product after molding is reduced, thereby the shrinkage tendency is reduced, and the problem of heat shrinkagedeformation of the finished product is solved while ensuring "light, flexible, soft and elastic" basic characteristics.
Owner:林伟坤
Preparation and application of novel umbrella-type light-emitting material with pyrrole structure
InactiveCN109456247AImprove three-dimensional structureImprove thermal stabilityOrganic chemistrySolid-state devicesSimple Organic CompoundsAryl
The invention discloses preparation and an application of a novel umbrella-type light-emitting material with a pyrrole structure. The umbrella-type organic compound with the pyrrole structure has goodmolecular stability, a prepared OLED (organic light-emitting diode) device has superior photoelectric properties, high heat stability, low driving voltage and high efficiency, the service life of thedevice is prolonged, and the requirements of device manufacturers can be effectively met. The structure of the organic compound is as shown in a general formula (1), Ar is indicated as substituted orunsubstituted C6-60 aryl and 5-60 heterogeneous aryl containing one or more heteroatom, and the heteroatoms are nitrogen, oxygen or sulfur.
Owner:烟台九目化学股份有限公司
Organic aromatic amine luminescent material containing seven-membered ring
InactiveCN109369420AStable structureEasy transferOrganic chemistrySolid-state devicesThermal stabilityElectron transfer
Owner:烟台九目化学股份有限公司
Recombinant feline herpesvirus type 1 gB-gD protein and application thereof
ActiveCN113845576ANot pathogenicReduce manufacturing costAntibody mimetics/scaffoldsVirus peptidesDimerImmunogenicity
The invention discloses a recombinant feline herpesvirus type 1 gB-gD protein and application thereof. The recombinant feline herpesvirus type 1 gB-gD protein comprises a first protein having a sequence as shown in SEQ ID NO:2 and / or a second protein having a sequence as shown in SEQ ID NO:6. A vaccine comprises the recombinant feline herpesvirus type 1 gB-gD protein and a pharmaceutically acceptable carrier. The recombinant feline herpesvirus type 1 gB-gD protein provided by the invention is long in half-life period, high in molecular stability, capable of forming a dimer, especially a heterodimer, strong in immunogenicity, capable of being prepared in a bioreactor large-scale serum-free suspension culture mode through a mammalian cell expression system, high in expression level and good in protein immunogenicity; and the prepared vaccine also has the advantages of easy quality control, batch-to-batch stability, low production cost and the like.
Owner:SUZHOU MIDI BIOTECH CO LTD
Mixed absorbing agent for catching or separating carbon dioxide
The invention relates to a mixed absorbing agent for catching or separating carbon dioxide from gas mixture, which mainly comprises the components by weight percent: 10-50wt% of 3-dimethyl amino-1-propyl alcohol, 5-10wt% of primary amine and / or secondary amine and balance water. The absorbing agent has high solubility for low-pressure carbon dioxide, good desorbing effect, lower reaction heat of absorption reaction and lower energy consumption for catching or separating the carbon dioxide; and as the 3-dimethyl amino-1-propyl alcohol is a tertiary amine and has high boiling point and better molecular stability than primary amine and secondary amine, so that the mixed absorbing agent can greatly reduce the degradation consumption of solvent in the using process, has good catching effect, and can be used for catching or separating the carbon dioxide in various gas mixtures such as flue gas, refinery gas, natural gas, synthesis gas, shift gas, hydrogen preparation gas and the like.
Owner:TSINGHUA UNIV
Pyrrolopyrrole organic semiconductor material containing free radicals, preparation method and application thereof
ActiveCN110041337AImprove performanceHigh absorption coefficientOrganic chemistrySolid-state devicesOrganic field-effect transistorOrganic semiconductor
The invention discloses a pyrrolopyrrole organic semiconductor material containing free radicals, a preparation method and application thereof and belongs to the technical field of photoelectric materials. The preparation method comprises the following steps: mixing a pyrrolopyrrole halogenated derivative with a monomer I, or mixing a pyrrolopyrrole organic tin compound and a monomer I' to obtaina pyrrolopyrrole organic semiconductor material; enabling the pyrrolopyrrole organic semiconductor material to react with an oxidant to obtain the pyrrolopyrrole organic semiconductor material containing the free radicals. The preparation method disclosed by the invention is simple in synthesis routine and easy in synthesis. The pyrrolopyrrole organic semiconductor material containing the free radicals prepared by the invention has the advantages that the electron mobility is high, the molecular stability is good, the absorption intensity is high, the absorption waveband is narrow, the absorption wavelength reaches a near-infrared waveband, and the pyrrolopyrrole organic semiconductor material containing the free radicals can be used as a free-radical material of devices such as near-infrared and narrowband photoelectric detectors and organic field effect transistors.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA
Low-dielectric and low-dielectric-loss halogen-free resin composition, prepreg and laminated board
InactiveCN110066493ALow dielectric constantReduce dielectric lossElectrical equipmentGlass/slag layered productsDielectric lossMoisture absorption
The invention discloses a low-dielectric and low-dielectric-loss halogen-free resin composition, a prepreg and a laminated board. The halogen-free resin composition is made from, by weight, 100 partsof epoxy resin, 2-45 parts of a double-deck silsesquioxane curing agent, 10-50 parts of cyanate modified polyphenyl ether resin, 10-25 parts of benzoxazine resin, and 0.001-5 parts of an accelerator.A high-Tg resin material excellent in dielectric property is obtained through graft copolymerization of the silsesquioxane curing agent with a special structure, after curing, the resin material has higher molecular stability and lower chain-segment motion ability, and thus the metal clad laminated board prepared from the resin is more excellent in dielectric property, heat resistance, mechanicalproperty and moisture absorption resistance and the like.
Owner:ZHEJIANG WAZAM NEW MATERIAL CO LTD +1
Methods and compositions for increasing biological molecule stability
ActiveUS20090092982A1Enhancing foldingImprove stabilityColony-stimulating factorMicrobiological testing/measurementMolecular stabilityBiomolecule
Owner:RGT UNIV OF MICHIGAN
Polymeric dispersing agent for textile dyes and preparation method of polymeric dispersing agent
InactiveCN109972424AImprove stabilityImprove thermal stabilityDyeing processTitanium sulphateMolecular stability
The invention discloses a polymeric dispersing agent for textile dyes and a preparation method of the polymeric dispersing agent in the technical field of fine chemical engineering. The preparation method of the polymeric dispersing agent for the textile dyes comprises the following steps that step 1, 10-30 parts of butyl methacrylate is added into a reactor of 60-80 DEG C; step 2, 4-6 parts of acrylic acid and 1 part of butyl methacrylate are mixed and added into another dropping funnel, an initiator is added, a reaction is performed for 2 hours; 4-6 parts of titanium sulphate is put into thereactor, the initiator is poured into the reactor through the funnel and is slowly stirred; step 3, substances after the reaction is evaporated to obtain a solid substance, the solid substance is added into the reactor, and 20-60 parts of water is added to form an aqueous solution; through stearamide and higher alcohols which are added in the prepared materials, while the own molecular activity is improved, the molecular stability of the butyl methacrylate in the mixed solution is also improved.
Owner:扬州市立达树脂有限公司
Simple and rapid method for extracting rice DNA
The invention provides a method for extracting rice DNA. The method comprises the following steps: cutting rice leaves into pieces, placing the rice leaves into a 2ml centrifugal tube, adding an extracting solution, treating the rice leaves in an oven at 65 DEG C for about 30 min, carrying out centrifugation, placing the supernatant in a 96-well plate containing isopropanol, carrying out standingfor about 30 min, and carrying out centrifugation to obtain a white solid, namely DNA. Compared with a traditional DNA extraction technology, the method provided by the invention has the advantages ofsimple and rapid operation, less reagent used, low cost, no need of phenol and chloroform extraction, environment-friendliness and no need of liquid nitrogen or frozen sample. The DNA extracted by the method provided by the invention has the characteristics of high yield, good quality, high success rate of PCR amplification, low cost, good universality, strong molecular stability and the like.
Owner:XUZHOU INST OF AGRI SCI IN JIANGSU XUHUAI DISTRICT (JIANGSU XUZHOU SWEETPOTATO CENT)
Aromatic amine compound, material containing same and organic electroluminescence device
ActiveCN110041209AImprove compound efficiencyHigh refractive indexAmino preparation from aminesSolid-state devicesRefractive indexOrganic electroluminescence
The invention discloses an aromatic amine compound with the structural formula I as shown in the specification. The compound has relatively high glass transition temperature and molecular stability, has low light absorbance and high refractive index in the field of visible light, and can effectively enhance the light extraction efficiency of OLED devices and increase the visual angle when appliedonto CPL layers of the OLED devices.
Owner:SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD
Bivalent IgY antibody constructs for diagnostic and therapeutic applications
InactiveUS7696323B2Improve featuresUseful applicationImmunoglobulins against virusesAntibody ingredientsSerum igeHeavy chain
This invention relates to the field of recombinant antibody technology. It provides novel recombinant IgY antibody constructs for diagnostic and therapeutical applications. The bivalent antibody constructs display a heterotetrameric or homodimeric format stabilized by disulfide bonds. The constant heavy chain domains CH2-CH4 are partly or completely of avian origin, whereas the VH, VL, CL, and CH1 domains as well as the hinge region may be of avian origin or derived from any other species. The invention allows to combine the advantages of IgY antibodies with those of established mammalian monoclonal antibodies. IgY antibody constructs comprising nonglycosylated IgY constant heavy chain domains allow to reduce unwanted interactions with C-type lectins, e.g., in human sera. Furthermore, chimeric IgY antibody containing mammalian VH, VL, CL, and CH1 domains as well as a mammalian hinge region provide a higher molecular stability than IgY antibodies in acidic conditions and, thereby, are especially suited for peroral therapeutic applications.
Owner:PLS DESIGN
Recombinant feline herpesvirus type 1 gb-gd protein and its application
ActiveCN113845576BExtended half-lifeImprove stabilityAntibody mimetics/scaffoldsVirus peptidesDimerImmunogenicity
The invention discloses a recombinant feline herpesvirus type 1 gB-gD protein and application thereof. The recombinant feline herpesvirus type 1 gB-gD protein comprises: the first protein having the sequence shown in SEQ ID NO:2; and / or, the second protein having the sequence shown in SEQ ID NO:6. The vaccine comprises the recombinant feline herpesvirus type 1 gB-gD protein and a pharmaceutically acceptable carrier. The recombinant feline herpesvirus type 1 gB-gD protein provided by the invention has a long half-life, high molecular stability, can form dimers, especially heterodimers, and has strong immunogenicity. The preparation of large-scale serum-free suspension culture in bioreactor not only has high expression level and good protein immunogenicity, but also has the advantages of easy quality control, batch-to-batch stability, and low production cost.
Owner:苏州沃美生物有限公司
New coronavirus single-chain antibody, quality control substance and preparation method
ActiveCN112538111BHigh sensitivityImprove stabilityImmunoglobulins against virusesFermentationIgm antibodyChimeric antibody
The present invention relates to a new coronavirus single-chain antibody, a quality control product and a preparation method, which include a light chain variable region and a heavy chain variable region in sequence from the N segment to the C terminal, and the amino acid sequence of the light chain variable region is as shown in SEQ As shown in ID NO:1, the amino acid sequence of the heavy chain variable region is shown in SEQ ID NO:2. The novel coronavirus single-chain antibody of the present invention has high sensitivity and good stability, and is very suitable for the preparation of quality control products. Moreover, on the basis of this variable region sequence, further use gene recombination technology to construct a human-mouse chimeric IgM antibody without a CH1 fragment, thereby improving molecular stability and specific binding ability. The novel coronavirus single-chain antibody prepared by the invention can be applied to a chemiluminescence platform for quality control detection, can effectively measure activity, and can overcome the defects of poor detection sensitivity and low specificity of general 2019‑nCoV IgM antibodies.
Owner:深圳市昭蓝生物科技有限公司
Rhodamine-benzothiazole functionalized photosensitive probe and its synthesis method and application
ActiveCN112341471BIncreased Reactive Binding SitesGood biocompatibilityOrganic chemistryFluorescence/phosphorescenceThiazoleBinding site
The invention belongs to the technical field of chemical detection, and relates to a rhodamine-benzothiazole functional photosensitive probe and its synthesis method and application. The rhodamine-benzothiazole functional photosensitive probe has a structure that can be used for ClO ‑ Detection and ClO in cells ‑ detection. The rhodamine-benzothiazole functionalized photosensitive probe provided by the present invention has a six-membered spironolide hydrazide structure, has high molecular stability of the probe, increases the reactive binding sites of the probe, and has good bio-affinity, and can be used in environment and environment. ClO in biological cells ‑ The detection has the characteristics of good anti-interference ability, short response time, long fluorescence duration, wide applicable pH range, high detection sensitivity and wide detection concentration range, and has important scientific research value and broad application and promotion prospects.
Owner:XIAN UNIV OF SCI & TECH
Organic photoelectric material with boron bridged 2,2'-dithiophene structure and application of organic photoelectric material
InactiveCN108191897AImprove electroluminescence performanceImprove stabilitySolid-state devicesSemiconductor/solid-state device manufacturingLow voltageBoron
The invention relates to an organic photoelectric material with a boron bridged 2,2'-dithiophene structure and an application of the organic photoelectric material, and belongs to the field of organicphotoelectric materials. According to the organic photoelectric material provided by the invention, boron bridged 2,2'-dithiophene is adopted as a parent body, so that the molecular stability is greatly improved, the electron affinity and conductivity are improved, and the transmission of electrons is facilitated; aromatic amines with good hole transmission properties are combined, so that the photoelectric material with bipolar transmission capability is formed, the transmission of holes and electrons in a light-emitting layer is balanced, and the luminous efficiency is greatly improved; theorganic photoelectric material containing the boron bridged 2,2'-dithiophene structure provided by the invention has a space structure of a rigid trapezoidal plane structure, so that the molecular potential barrier is reduced, and the electron affinity is improved; and the organic photoelectric material is used as a light-emitting material of an organic light emitting diode (OLED) light-emittingdevice, the produced OLED device has the effect characteristics of high brightness, high efficiency and a low voltage.
Owner:VALIANT CO LTD
Automatically heated catalytic converter
InactiveUS20170101915A1Reduce decreaseShort timeGas treatmentPhysical/chemical process catalystsPlatinumEngineering
The present invention is based on the application of heating resistors by a temperature regulation circuit in certain points of the catalyzer so that this comes into operation in the least time possible, reducing most of the amount of low molecular stability or environmentally harmful substances. Likewise, little tumult are added to each monolith duct to raise exhaust gas turbulence and increase the contact between the reduction and oxidation agent, whether it be platinum, palladium and rhodium.
Owner:INST TECHCO DE SANTO DOMINGO INTEC
A kind of curcumin micellar nasal administration solution and preparation method thereof
ActiveCN104997727BImprove solubilityImprove stabilitySenses disorderNervous disorderSolubilityPolyethylene glycol
Owner:SHANDONG EYE INST
Nucleic acid delivery system as well as preparation method and application thereof
ActiveCN113082001APromote degradationGood biocompatibilityOrganic active ingredientsGenetic material ingredientsLysosomeNanoparticle
The invention relates to a nucleic acid delivery system as well as a preparation method and application thereof. The nucleic acid delivery system is nanoparticles formed by entrapping nucleic acid by taking polyhydroxyalkanoate and an amine material as carriers. According to the invention, the polyhydroxyalkanoate compounded amine material is creatively used as a carrier for entrapment of nucleic acid, the amine material is combined with nucleic acid molecules, and the positive electricity provided by the amine material can improve the loading efficiency of nucleic acid and improve the cellular uptake efficiency of nucleic acid; wherein the polyhydroxyalkanoate has good biodegradability and biocompatibility, and can protect the molecular stability of the nucleic acid in the delivery process, so that the nucleic acid is prevented from being degraded by nuclease and lysosome, the cellular uptake efficiency of the nucleic acid is increased, and the release time of the nucleic acid is prolonged. The finally prepared nucleic acid delivery system has good nucleic acid entrapment capacity, can effectively deliver nucleic acid drugs into cells, and has the advantages of high transfection rate and low cytotoxicity.
Owner:GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI
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