The invention discloses a safe transportation device for high-pressure combustible experimental gas and a gas supply method thereof. The device comprises a combustible experimental gas cylinder, an inert gas cylinder, a filter, a pipeline pressure reducing valve, a manual stop valve, a pneumatic stop valve, a pressure transmitter, a vacuum pump, a pressure gauge, a vacuum gauge, an electromagneticvalve, a combustible gas detector, a combustible gas alarm controller, a metal pipeline and the like. The device can be used for: 1) transporting the combustible gas to experimental equipment safely;2) adjusting the gas pressure in full range during the using process; 3) supplying gas continuously or intermittently for laboratory equipment; 4) conduting air tightness inspection to the equipmentbefore the experiment and supplying gas for cleaning tail gas after the experiment; 5) replacing the high-pressure gas cylinder safely and conveniently; 6) detecting combustible gas concentration in real time to maintain laboratory safety. With good air tightness, high cleanliness, high durability and safety reliability, the transportation device and method provided by the invention can meet the requirements of continuous gas supply and intermittent gas supply for the laboratory equipment.