393 results about "Foreign body sensation" patented technology

The present invention provides a method for treating dry eye condition in an individual comprising administrating to said individual an amount of A3 adenosine receptor (A3AR) agonist, the amount being effective to ameliorate symptoms of dry eye in the individual. In accordance with one embodiment, the dry eye condition is manifested by one or more ophthalmologic clinical symptoms selected from foreign body sensation, burning, itching, irritation, redness, eye pain, blurred vision, degraded vision and excessive tearing. A preferred A3RAg in accordance with the invention is N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide (IB-MECA).

The present invention relates to oxygenated ophthalmic topical compositions and methods of administering oxygenated ophthalmic topical compositions. The present invention also encompasses methods for making and administering the oxygenated ophthalmic topical compositions for use in treating or ameliorating pathologic conditions, complications, diseases and symptoms related to hypoxia of the anterior eye structure, including corneal neovascularization (CNV), edema, abrasions, infections, infiltrates, dry eye syndrome, contact lens intolerance; and redness, blurred vision, discomfort, foreign body sensation, photophobia, and irritation.

The invention discloses an asthenopia-relieving healthcare food and a preparation method thereof. The healthcare food comprises the following main raw materials: 0.5-10 parts of medlar, 0.1-6 parts of chrysanthemum, 0.5-10 parts of a bilberry extract and 0.005-0.08 part of lutein. The raw materials are extracted, concentrated and dried to prepare lozenges, capsules or granules. The healthcare food contains various nutrients necessary to eyes, has the effects of relieving asthenopia and improving eyesight, can be used for relieving symptoms such as eye pain, soreness, swelling, burning sensation, foreign body sensation, tearing, photaesthesia, blurred vision and eye dryness, is a traditional Chinese medicine preparation with homology of medicine and food, and is safe to take.

The invention provides a base hinge point position self-adjusting six-degree-of-freedom neck part flexible exoskeleton system which has a power-assistance function, replaces a wearer to bear the weight and inertia, relieves a heaviness sense, a restriction sense and a foreign body sensation brought to the wearer by a load, improves the flexibility of connection between the wearer and the base hinge point position self-adjusting six-degree-of-freedom neck part flexible exoskeleton system, and has a head position and pose detection function. The base hinge point position self-adjusting six-degree-of-freedom neck part flexible exoskeleton system comprises a base bottom plate; unit brackets are arranged on the base bottom plate through base hinge point position adjusting mechanisms; servo motors and steel rope windings are arranged on the unit brackets; universal pulleys are rotationally arranged on the unit brackets; three compound spherical hinges are uniformly distributed on a load mounting platform in the circumferential direction; each of an inner ear and an outer ear of each compound spherical hinge is connected with one steel rope winding through a steel rope correspondingly; joint space force detection units are connected with the steel ropes in series; rotating speed and corner sensors are arranged on the servo motors; outputs of the joint space force detection units and the rotating speed and corner sensors are connected with a control unit; and an output of the control unit is connected with the servo motors.

The invention discloses throat clearing and moistening healthcare tea which comprises the following raw materials in parts by weight: 2-3 parts of momordica grosvenori, 2-3 parts of terminalia chebula retz, 1-2 parts of platycodon grandiflorum, 1-2 parts of sandalwood olives, 0.5-1 part of radix ophiopogonis, 0.5-1 part of mint, 1-3 parts of rock candy, 1-2 parts of liquorice, 1-2 parts of honeysuckle, 1-2 parts of chrysanthemum morifolium ramat, 1-2 parts of green tea and 0.5-1 part of dried orange peels. The throat clearing and moistening healthcare tea is easily available in raw material, simple and convenient to prepare, fragrant and sweet in mouth feel and convenient to drink, has the effects of clearing and moistening the throat, moistening the lung to relieve a cough, clearing heat and toxins and the like, can be used for relieving symptoms such as nausea, foreign body sensation and hoarse voice caused by acute and chronic sphagitis, and has a healthcare effect for the throat after being drunk for a long term.

The invention relates to a portable electrocardio electrode plate which comprises a plurality of electrode plates, wherein the electrode plates are arranged in a broken line shape and connected with one another sequentially; the broken line shape is specifically a Z shape of which the included angle is an obtuse angle; and the electrode plates are connected through silica gel. The portable electrocardio electrode plate also comprises electrode plates of at least three monomers. The electrode plates are fixedly connected, so that during use, electrodes do not need to be fixed one by one, and the positions of the six electrode plates can be fixed accurately only by fixing the positions of two or three of the electrode plates according to the positions. The portable electrocardio electrode plate is convenient to use and simple to operate; patients who do not know the principles of medical science can perform electrocardio measurement in short time; the portable electrocardio electrode plate has a small size and is convenient for families to use; and the backing of the electrode plate adopts 20-degree medical silica gel, so foreign body sensation is avoided with the portable electrocardio electrode plate is worn and the portable electrocardio electrode plate is convenient to adhere and tear down.

The invention discloses a removable denture and a manufacturing process thereof and belongs to the technical field of mouth rehabilitation. The removable denture has the advantages that the foreign body sensation is low and the simulation performance is good after the removable denture is worn. According to the technical scheme, the removable denture comprises bionic teeth and a base plate; the bionic teeth are fixed to the base plate, bionic resin fixing snap rings stretching to the two ends are integrally arranged on the lip and cheek side of the base plate, stainless steel wire bent snap rings and / or stainless steel wire continuous snap rings stretching to the two ends are fixed to the tongue palate side of the base plate, fixing regions fixed with natural teeth are formed on the two sides of the base plate by the bionic resin fixing snap rings and the stainless steel wire bent snap rings, and tooth brackets are arranged on the portions, close to the two sides of the fixing regions, of the base plate.

A dental bracket has a base and an engaging unit. The base has two engaged protrusions and two limiting protrusions. The engaging unit is mounted on the base and forms a space between the base and the engaging unit. The engaging unit has a plate, two engaging arms, and a blocking protrusion. The plate has a first surface and a second surface being flat and opposite the first surface. The two engaging arms are formed on the first surface of the plate and respectively engaged with the two engaged protrusions of the base. The blocking protrusion is formed on the first surface of the plate, is arranged between the two limiting protrusions of the base, and divides the space into two channels for inserting an archwire. The second surface of the engaging unit is flat and is able to decrease the foreign body sensation in the mouth.

The invention provides a capacitive elastic strain sensor. Elastic textile material is used as a matrix. The sensor includes an elastic bonding layer, a first conductive layer, an elastic dielectric layer, a second conductive layer and an elastic packaging layer. The capacitive elastic strain sensor can be used in a wearable product to detect body part stress strain such as joint bending, muscle stretching or bending, vertebral body stretching or bending and human body breathing, has comfort and no foreign body sensation, and can maintain performance stability of the sensor under the action ofexternal force such as folding, kneading and squeezing in practical application due to lower conductive layer thickness.

The invention discloses a traditional Chinese medicine eye care mask and relates to the technical field of eye care masks. A preparation method of the traditional Chinese medicine eye care mask comprises the steps that ganoderma, flos chrysanthemi indici, licorice roots, cassia seeds, radix angelicae dahuricae, cortex phellodendri, Chinese wolfberry fruits, radix ophiopogonis, flos lonicerae, rehmannia roots, folium mori, chuanxiong rhizomas, kudzu vine roots and mint leaves are placed in distilled water with the weight five times that of the medicine mixture for soaking, then the mixture is decocted for 30-40 minutes, filtrate is filtered, and the filtrate is subjected to reduced pressure concentration, so that a concentrated solution is obtained for use; silk patch cloth is cut to be oval and then soaked into the concentrated solution, high temperature sterilization and disinfection are conducted, then each piece of the silk patch cloth is encapsulated into an aluminum plastic film-coated bag together with the concentrated solution, sealing is conducted, and the traditional Chinese medicine eye care mask is obtained. According to the traditional Chinese medicine eye care mask, traditional Chinese medicine constituents which have the functions of invigorating blood circulation, dispelling wind, clearing away heat, calming the liver and improving eyesight are added to the formula, and multiple effects of treating pseudomyopia, preventing and treating xerophthalmia, protecting eyes, improving eyesight and the like are achieved. Meanwhile, such asthenopia symptoms as visual impairment, eye tiredness, photaesthesia, ache, tears-down, foreign body sensation, dry eyes and eye spasm can be improved or alleviated, and compared with traditional medicinal treatment, the eye care mask is more convenient and faster to use.

A seat with a seating sensor is provided, in which no foreign body sensation is felt at all even when a sensor for detecting seating is provided, and the seat with the seating sensor is easily manufactured. A supporting member 2 is integrally provided with a bottom face of the pad 1. A sheet-like seating sensor 4 and a plate 5 serving as a rigid plate-like member 5 for covering the seating sensor 4 are disposed between the bottom face of the pad 1 and the supporting member 2. The seat with the seating sensor is molded by means of disposing the supporting member 2, the seating sensor 4, and the plate 5 in a stacked state, shown in the drawings, in a metallic mold for molding the pad 1, feeding raw liquid of urethane into the metallic mold, and foaming.

The present invention relates to a monofilament with a segmented pie structure formed by conjugated spinning of degradable polymers and non-degradable polymers, a hernia mesh having improved flexibility and biocompatibility, and a preparation method thereof. More specifically, the hernia mesh of the present invention having improved flexibility and biocompatibility is prepared using the monofilament obtained by conjugated spinning of degradable polymers and non-degradable polymers into a segmented pie form, to control it to be gradually degraded in the body, whereby the stiffness of the early stage is removed, and thereby the foreign body sensation is also removed.

The invention relates to a matrine diatomic alcohol plastid temperature-sensitive gel and a preparation method thereof, and aims to overcome the defects of vaginal dosage forms in the prior art. By adopting the matrine diatomic alcohol plastid temperature-sensitive gel, the medicine can be conveniently used, a patient does not have foreign body sensation, a medicine storage is formed in a vagina at the same time, the acting time of the medicine is long, and the bioavailability of matrine can be fully improved. The matrine diatomic alcohol plastid temperature-sensitive gel is prepared from the following raw materials in percentage by weight: 0.25-1.5% of matrine, 0.25-1.5% of lecithin, 0.5-1% of chitosan, 13-30% of low-molecular-weight alcohol, 38-55% of a phosphate buffer solution, 15-35% of poloxamer and 5-10% of glycerol. The diatomic alcohol plastid using ethanol and propanediol as softening agents has high encapsulation efficiency and stability, is stable in structure, can increase the in vivo and in vitro pereutaoeous permeation to ensure that the medicine can be slowly released, thereby improving the therapeutical effect; in addition, the gel does not have obvious toxicity.

The invention relates to a polystyrene sulfonate-containing gel preparation for therapy of hyperpotassemia, wherein the particle size of polystyrene sulfonate is controlled within the range of at least 5-100 mum, the viscosity of its solution before gelation is adjusted depending on the particle size by adding a thickening agent, and the polystyrene sulfonate particles after gelation is uniformly dispersed therein. More preferably, a water-displacing agent is contained, whereby the amount of water in the preparation is reduced. This gel preparation does not cause a sense of foreign matter or a sense of roughness in the oral cavity upon ingestion and intake, thus making it unnecessary to drink water for ingestion, and further its water content is low, so that control of water intake is made easy, even in the case of a patient with renal insufficiency who is subjecting to restriction in intake of water to significant improve the quality of life of the patient.

The invention belongs to the technical field of gynecologic medicines and provides gynecologic vagina gel and a preparing method thereof to solve the problem that a traditional gynecologic cleaning solution kills many probiotics while killing pathogenic bacteria to cause dysbacteriosis in the vagina and vagina hypoimmunity, and colpitis recurrently attacks. Nano bubble hydrogen-enriched water, man-made ionized acidic electrolyzed oxidizing water and a hydrophilic gel matrix are mixed according to a certain ratio to prepare the gel with the pH value of 3.8-6.0. The gynecologic vagina gel maintains microecological balance of the vagina, improves the cleanliness degree of the vagina, improves the immunity of vagina mucosa and achieves the purposes of preventing gynecologic vagina inflammation and reducing the recurrence rate of gynecologic colpitis and is safer and more effective. The gynecologic vagina gel has the advantages of being high in transdermal absorption ratio, high in stability, convenient to deliver, good in vagina anelasticity, long in drug action time, not prone to deformation and easy to store, can fully release drugs, causes no foreign body sensation in the vagina, does not hurt the vagina and does not pollute clothes after being used.

Provided is an ophthalmic nanoemulsion composition and a method for preparing the same which increases the solubility of cyclosporine as an active ingredient and improves the stability of the ophthalmic composition by mixing cyclosporine, a nonaqueous solvent, an emulsifier, and an aqueous solvent, and a method for preventing or treating dry eye syndrome using the same. The ophthalmic nanoemulsion composition is characterized by having an average particle size of 200 nm or less, preferably 100 nm or less, and having a very narrow particle distribution. Therefore, sterilizing filtration is available, stability is improved, and the composition has superior effect in clinical treatment of dry eye syndrome while minimizing foreign body sensation and visual disturbance, and thus the ophthalmic nanoemulsion composition of the present disclosure can be effectively used as an ophthalmic composition.

The present invention provides a method for treating dry eye condition in an individual comprising administrating to said individual an amount of A3 adenosine receptor (A3AR) agonist, the amount being effective to ameliorate symptoms of dry eye in the individual. In accordance with one embodiment, the dry eye condition is manifested by one or more opthalmologic clinical symptoms selected from foreign body sensation, burning, itching, irritation, redness, eye pain, blurred vision, degraded vision and excessive tearing. A preferred A3RAg in accordance with the invention is N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide (IB-MECA).

The invention belongs to a new application of a medicine, in particular relating to an application of immunosuppressive agent tacrolimus in medicine and preparation thereof for treating dry eye syndrome. Research shows that the tacrolimus eye drops have obvious effect in a model of animal dry eye syndrome, can relieve symptom of the patient such as sears optical, inflammation, itch, photophoby, foreign body sensation, asthenopia and the like, can improve vision of the patient, effectively improve the eye comfort level of the dry eye syndrome patient, and relieve the terrible emotion caused by discomfort eye part. The mechanism of action of the invention needs to be studied further.

The invention discloses a medical repairing mesh and a manufacturing method. The mesh is a warp knitted eyelet fabric formed by polypropylene monofilaments through warp knitting. The eyelet fabric comprises a plurality of hexagonal eyelets which are adjacent to one another and vertically arranged, and further comprises the polypropylene monofilaments enabling the hexagonal eyelets which are adjacent to one another and vertically arranged to be connected transversely and alternately. The diameters of the polypropylene monofilaments are 0.1-0.2mm, each hexagonal eyelet is in a regular hexagon shape, and the area of each hexagonal eyelet is 5.8-16.2mm*2. The mesh is high in mechanical strength and capable of completely meeting supporting requirements for human organs; the mesh is light and thin, so a patient feels slight foreign body sensation in a use process; the mesh is high in void ratio which is larger than 72%; in addition, the mesh is enlarged, meanwhile deformation in longitudinal and transverse directions of the mesh is reduced, and therefore the requirements of the mesh for a light weight and of tissue growth substances for exchanging can be better met, and tissue repair is facilitated.

The present application relates to a hernia mesh and its preparation method. A preparation method of hernia mesh comprises selecting and adding a first material particle into a filler tube attached to a 3D printer, and making an external pressure pipe connected; heating the filler tube to a first temperature, and maintaining for a first preset time to remove moisture contained in the first material particle; continuously heating the filler tube to a second temperature, and maintaining for a second preset time to completely melt the first material particle; continuously heating filler tube to a third temperature, and using a designed hernia mesh 3D print file to prepare the hernia mesh by the 3D printer. The hernia mesh prepared has controllable pore size, biocompatibility, tensile strength, and elasticity; the preparation process is convenient and quick, reducing the cost; the patient's foreign body sensation and discomfort can be reduced.

The invention relates to Chinese medicinal throat-disinhibiting tea for treating chronic pharyngitis and belongs to the technical field of Chinese medicinal compound compatibility. The Chinese medicinal throat-disinhibiting tea comprises the following components by weight: 3g of lonicera chrysantha flower, 3g of root of rehmannia, 3g of figwort root, 3g of dwarf lilyturf tuber, 3g of platycodon root, 1 fruited scaphium seed and 3g of liquoric root. Chinese medicinal plants of the formula are natural Chinese medicinal decoction tablets. The compatible Chinese medicinal throat-disinhibiting tea has the effects of clearing heat and detoxicating, eliminating phlegm and disinhibiting throat, and engendering liquid and allaying thirst, and has an extremely good curative effect on the chronic pharyngitis with the symptoms such as pharyngeal discomfort, foreign body sensation, itching, slight pain, slight cough, vomiturition and the like. The Chinese medicinal tea has simple compatibility, is convenient to use, has low price, does not have toxic or side effects, is suitable for both children and adults, can be used as tea and medicines, and has the clinical effective rate of 100 percent through clinical observation of 150 patients.

The invention discloses a temperature-sensitive gel for a skin injury and a preparation method of the temperature-sensitive gel and relates to the technical field of skin repair administration. The temperature-sensitive gel is prepared from the following raw materials in parts by weight: 5-20 parts of poloxamer 407, 0.01-0.1 part of a bacteriostatic agent, 0.001-0.05 part of a human epidermal growth factor, 0.2-1.0 part of a humectant, 2-10 parts of sodium hyaluronate and the balance of water for injection water. The temperature-sensitive gel is prepared from the poloxamer 407 as a main raw material, and exists in a solution form at a low temperature; administration is convenient; the temperature-sensitive gel is converted into a gel state at a high temperature and is smooth and soft in surface, free of thrill to the administration part, free of foreign body sensation and good in biocompatibility; the sodium hyaluronate is very high in biocompatibility, beneficial to long-term moisture retention of the skin and beneficial to tissue cell regeneration and is capable of compacting the skin and preventing dehydration; and the human epidermal growth factor has an acceleration effect on mucosa repairing of the skin injury, so that the wound healing cycle is shortened to meet the structure design and clinical requirements.

The invention discloses a composition for preventing and treating asthenopia and a preparation method and application of the composition. Each 100 parts by weight of composition is prepared from the following raw materials in parts by weight: 10-40 parts of semen cassia, 5-30 parts of blueberries / bilberries, 10-30 parts of lutein ester / lutein / lutein ester microcapsule powder, 10-30 parts of purple perilla seed oil / perilla oil microcapsule powder, 1-15 parts of phospholipid, 1-15 parts of guarana extracts, 0.1-3 parts of taurine, 0.01-0.5 part of vitamin C and 0.001-0.1 part of vitamin A / beta carotene. The composition can be compounded with an adjuvant for preparing drugs, health products and foods for preventing and treating asthenopia. The composition has the effects of supplementing eyes with nutrients and preventing and treating asthenopia, and can be applied to prevention and treatment of diseases, such as asthenopia, eye dryness, foreign body sensation eyelids heaviness, blurred vision, photophobia, tears, eyeball dryness, eye pain and eye congestion.

The invention belongs to the technical field of medicines and specifically relates to monosialotetrahexosyl ganglioside sodium for injection and a preparation method thereof. The monosialotetrahexosyl ganglioside sodium for injection provided in the invention contains GM1, gelatin and PLGA (Polylacticcoglycollic Acid). A microsphere injection prepared from the monosialotetrahexosyl ganglioside sodium for injection provided by the invention is good in reproducibility and encapsulation ratio; the drug-loading rate is improved; the drug release is continuous and stable; the dosage at a time is obviously reduced and the foreign body sensation is reduced; effective blood concentration can be maintained for a long time; the shortcoming of administration every day is avoided; the life quality of a patient is improved; and the problem of the fluctuation of the blood concentration caused by the conventional preparations is solved.

The invention provides an intelligent mattress. The intelligent mattress is characterized by comprising a mattress body, a sensor unit, a signal conditioning circuit and a signal processing circuit, wherein the sensor unit is arranged at a position, corresponding to the upper part of a human body, in the mattress body; the sensor unit comprises a sensor for collecting a pressure signal of a humanbody during sleeping; the signal conditioning circuit amplifies and filters the pressure signal; and the signal processing circuit calculates an output signal of the signal conditioning circuit to obtain sleep condition data. The intelligent mattress provided by the invention uses a single piezoelectric thin film sensor to replace a sensor group to measure various physiological signals, and has the advantages of fast response, high precision and small mutual interference. The piezoelectric thin film sensor is thin and is placed under a body, thus greatly reducing foreign body sensation and improving user comfort. A CC2541 micro-control chip is selected in the signal processing circuit, and both signal processing and communication are considered, thus reducing system size and power consumption and also saving the cost.

The invention discloses a medicine composition for treating xerophthalmia. The medicine composition is a preparation prepared from the following crude drugs in weight ratio: 12-18 parts of rhizoma polygonati, 8-12 parts of radix glehniae, 8-12 parts of medlar and 8-12 parts of chrysanthemum. According to the medicine composition disclosed by the invention, the rhizoma polygonati, the radix glehniae, the medlar and the chrysanthemum are reasonably combined, and thus, symptoms, such as dryness, foreign body sensation and hyperemia of bulbar conjunctiva of eyes, can be obviously improved. The medicine composition can be effectively used for treating xerophthalmia caused by video terminals, middle-aged and elderly xerophthalmia or diabetic xerophthalmia. Moreover, the clinical effect of the medicine composition is obviously superior to that of the Western medicine Tears Natural II group and the traditional Chinese medical science acupuncture group. The medicine composition is high in safety and good economic benefit, and a new medicine selection is provided for clinically treating the xerophthalmia.

The invention relates to a nifuratel-nysfungin gel and a preparation method of the nifuratel-nysfungin gel. The gel is prepared by nifuratel, nysfungin, hydrogel matrix and other auxiliary materials. According to the invention, the pharmaceutical ingredients are fully dissolved and evenly mixed in the gel matrix, and the pharmaceutical ingredients are fully contacted with the vaginal wall, so that the bacteriostasis of the medicine is fully exerted, and the nifuratel-nysfungin gel is safe and comfortable to use without foreign body sensation and greasy feeling. The nifuratel-nysfungin gel canbe used for treating vulva and vaginal infections and vaginal mixed infection caused by bacteria, trichomonas and candida, thus effectively maintaining the physiological environment of the vagina, providing the survival condition suitable for vaginal beneficial bacterium group and promoting disease recovery.

The invention discloses a traditional Chinese medicine preparation, in particular a traditional Chinese medicine preparation for treating ophthalmic diseases and a preparation method thereof. The prepared preparation is powder, ointment or gelata and belongs to the field of traditional Chinese medicine. The preparation has the advantages that the prescription originates from a classic and famous transcription of the Drug Standard of Ministry of Public Health of the People's Republic of China, the preparation method induces an ultrafine grinding technology for the first time, the raw materials (especially minerals and animal medicines) have thorough grinding, small granularity and large specific area, active ingredients can be better exposed to be in a release condition, so the dissolution rate of the active ingredients is greatly enhanced, the biological availability is enhanced multiply and the general reaction of clinic curative effect is good; at the same time, the foreign body sensation is obviously relieved and granular sensation almost disappears when the preparation is used by a suffer, thereby the preparation is an ideal medicine for treating ophthalmic diseases, is deeply popularized with suffers and has wide market prospect.

The invention belongs to the technical field of pharyngitis treatment, aims to solve the problems of long course of treatment and poor effect of the conventional traditional Chinese medicine for treating pharyngitis and provides a traditional Chinese medicine atomizing agent for treating pharyngitis. The traditional Chinese medicine atomizing agent is prepared from dried rehmannia root, scrophulariae, Chinese wolfberries, platycodon grandiflorum, red peony roots, honeysuckle, boat-fruited scaphium seeds, radix ophiopogonis, periostracum cicada and radix glycyrrhizae according to a certain ratio. The traditional Chinese medicines are decocted with conventional water for obtaining medical liquid, the medicine reaches to an affected part through aerosol inhalation, is quick in taking effect, and small in using amount, the concentration of the partial medicine is high, and the respiratory symptom can be improved rapidly. The traditional Chinese medicine atomizing agent can effectively relieve the symptoms of throat red and swollen, urtication, foreign body sensation, cough, difficulty in expectoration, hoarseness and the like.