Traditional Chinese medicine ophthalmic preparation and preparation method thereof
A technology of ophthalmic preparations and traditional Chinese medicines, which is applied in the direction of pharmaceutical formulas, medical preparations containing non-active ingredients, medical preparations containing active ingredients, etc., which can solve the problem of slow dissolution rate and release speed of active ingredients and the inability to ensure that the drugs are fully mixed and uniform , Low bioavailability of active ingredients and other issues, to achieve the effect of improving bioavailability, low energy utilization rate, and small particle size distribution range
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Embodiment 1
[0026] Embodiment 1 (prescription is derived from Zijinding eye drops)
[0027] Prescription: calamine (calcined) 140g borneol 80g gypsum (calcined) 200g
[0028] Daqing Salt 10g Borax 10g
[0029] Preparation method: take the above five flavors, take calamine (calcined) and gypsum (calcined) and coarsely pulverize them, put them in a vibrating ultrafine pulverizer for 15 minutes, then add three flavors such as borneol, continue to pulverize them for 55 minutes, and discharge , to prepare Zijinding Eye Powder.
Embodiment 2
[0030]Example 2 (the prescription comes from Bai Jingyu eye medicine)
[0031] Prescription: Stone Cassia (calcined) 100g, bear bile 20g, pearl (tofu broiled) 5g
[0032] Seaweed octopus 94.5g Calamine (calcined Coptis chinensis) 165g Naked sand (burnt) 0.6g
[0033] Musk 2.5g Borneol 162g
[0034] Preparation method: Take the above eight flavors, take cassia (calcined), octopus, calamine and borneol, and coarsely grind them, put them in a vibrating ultrafine pulverizer for ultrafine grinding for 10 minutes, then add four flavors such as bear bile, and continue to grind Pulverize for 60 minutes to obtain ultrafine drug powder, and set aside; take another 380g of Vaseline and an appropriate amount of liquid paraffin, heat at 150°C for 1 hour, filter, let cool to 55°C, add the above ultrafine drug powder, mix well, and obtain Bai Jingyu eye ointment.
Embodiment 3
[0035] Embodiment 3 (prescription is derived from Poyunsan eye drops)
[0036] Prescription: Bezoar 5g, musk 5g, borneol 4.68g
[0037] Cinnabar 16g Amber 24g Nauma 4.8g
[0038] Borax 48g Calamine (calcined) 625g
[0039] Preparation method: Take the above eight flavors, take cinnabar water and fly to very fine powder, dry naturally, pass through a 500-mesh sieve, and set aside; take calamine (calcined) and borax and put them in a vibrating ultrafine pulverizer for ultrafine grinding for 25 minutes, then Add the five flavors of bezoar and other five flavors, continue to ultrafinely pulverize for 25 minutes to obtain ultrafine drug powder, add the above-mentioned cinnabar ultrafine powder, mix well, and set aside; take another 20g of carbomer, add appropriate amount of water to swell for 24 hours, add triethanolamine to adjust When the pH reaches 8, add the above-mentioned ultrafine drug powder and 8 g of azone, stir evenly, add water to 2000 g, and stir evenly t...
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