The invention belongs to the preparation method of functionalized polyolefin resin. The polyolefin resin pre-irradiated with electron beam or γ-ray is mechanically mixed with functional monomer and electron-donating agent; the polyolefin resin is melted by reaction extrusion method. grafting reaction with functional monomers. The matrix resin is: polyethylene, polypropylene, ethylene-propylene random copolymer, ethylene-propylene block copolymer, ethylene-styrene random copolymer, polystyrene, high-impact polystyrene or acrylonitrile-butylene Diene-styrene copolymer resin; functional monomers are: acrylic acid, methacrylic acid, maleic acid, oleic acid, itaconic acid, citraconic acid, crotonic acid, glycidyl methacrylate, maleic acid Alkenic anhydride, (3-isocyanate-4-methyl) phenylcarbamate-2-propenyl ester; electron donating reagents are p-benzoquinone, triphenyl phosphate, carbon tetrachloride, caprolactam, dimethylformamide, Sulfuranilide, butanone, diphenylsulfoxide, or thionyl hydrazide.