The invention discloses a one-stage hydrogen separating and purifying method based on a pressure swing adsorption membrane and a device for realizing the same. The method comprises the following steps of: a, adsorption, wherein feed gas with hydrogen content of 75%, carbon dioxide content of 24.5%, carbon monoxide content of 0.5% and pressure of 1.2Mpa is fed into an adsorption tower, a hydrogen purification adsorbent filled in the adsorption tower adsorbs the carbon dioxide and the carbon monoxide in the feed gas, effective gas component hydrogen is output from the top of the adsorption tower, and the product hydrogen is sent to a user from the device through an outlet valve; and b, regeneration, wherein after the feed gas is adsorbed in the adsorption tower, equalized pressure drop and inverse discharge are performed on the adsorption tower, inversely discharged gas enters into a membrane separation unit, infiltration gas is stored in a buffer tank and then returned into the evacuated adsorption tower, and finally equalized pressure increasing and final charge are performed on the adsorption tower. By utilizing the process, the size of a pressure swing adsorption device can be reduced, the hydrogen yield is improved, and the cost is lowered.