Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

106 results about "Benzoylbenzene" patented technology

Benzophenone Phenyl ketone Diphenyl ketone Benzoylbenzene Benzoylphenyl Diphenylmethanone

Slow release of fragrant compounds in perfumery using 2-benzoyl benzoates, 2-alkanoyl benzoates or alpha -keto esters

A fragrance delivery system which releases fragrant alcohols upon exposure to light. The system comprises 2-benzoyl benzoates of general formulae which can comprise various subtituents R1-R5 as defined in the application and a substituted R* which is the organic part of a fragrant alcohol.
Owner:FIRMENICH SA

Radiation-crosslinkable elastomers and photocrosslinkers therefor

Radiation-crosslinkable elastomeric compositions containing:(a) an elastomeric polymer containing abstractable hydrogen atoms in an amount sufficient to enable the elastomeric polymer to undergo crosslinking in the presence of a suitable radiation-activatable crosslinking agent; and(b) a radiation-activatable crosslinking agent of the formula:wherein:X represents CH3-; phenyl; or substituted-phenyl; or substituted-phenyl with the proviso that any substituents on the substituted-phenyl do not interfere with the light-absorbing capacity of the radiation-activatable crosslinking agent and do not promote intramolecular hydrogen abstraction of the radiation activatable crosslinking agent;W represents -O-, -NH-, or -S-;Z represents an organic spacer selected from the group consisting of aliphatic, aromatic, aralkyl, heteroaromatic, and cycloaliphatic groups free of esters, amides, ketones, urethanes, and also free of ethers, thiols, allylic groups; and benzylic groups with hydrogen atoms intramolecularly accessible to the carbonyl group(s) present in the radiation-activatable crosslinking agent; and n represents an integer of 2 or greater. Further disclosed are novel photocrosslinkers based upon 2,4,6-tri(4-benzoylphenoxy)-1,3,5-triazines.
Owner:3M INNOVATIVE PROPERTIES CO

Liquid detergent composition with abrasive particles

The present invention relates to a dishwashing composition comprising abrasive particles and a suspending aid selected from the group consisting of crystalline wax structurants, micro-fibril-cellulose, amido-gellants, di-benzylidene polyol acetal derivatives, and mixtures thereof, and the process and use thereof.
Owner:THE PROCTER & GAMBNE CO

Fluorine-contained pyribenzoxim compound with herbicidal activity and preparation method thereof

The invention discloses a fluorine-contained pyribenzoxim compound with herbicidal activity and a preparation method thereof. The chemical name of the fluorine-contained pyribenzoxim compound is O-[2,6-bis(4,6-dimethoxy-2-pyrimidyl) oxy] benzophenone (2-trifluoromethyl) formaldoxime, the molecular formula of the fluorine-contained pyribenzoxim compound is C27H22N5O8F3, and the molecular weight of the fluorine-contained pyribenzoxim compound is 601.5. The fluorine-contained pyribenzoxim compound has three isomerides. The invention discloses molecular structural formulas and physical properties of the three isomerides. Meanwhile, the invention discloses a preparation method taking substitute trifluoromethyl-benzaldehyde, 2,6-bis(4,6-dimethyl-2-pyrimidyl-2-oxy) benzoic acid as raw materials. The control effect of the fluorine-contained pyribenzoxim compound reaches at least 94 percent on barnyard grass, Echinochloa colona, Paspalum distichum and Panicum crus in paddy fields. Meanwhile, the fluorine-contained pyribenzoxim compound is highly safe for paddy crops, is friendly to the environment, is low in toxicity and is wide in application prospect in the field of pesticides.
Owner:JINTAN XINDE AGRI SCI & TECH COMPANY

Sunscreen composition and preparation method thereof

The invention relates to a sunscreen composition (namely, Solarex-3, Solarex-3Complex or triple sunscreen compositions) which comprises 2-10wt% of methoxy cinnamic acid ester, 0.1-6wt% of ethylhexyl triazinone, 0.1-6wt% of lignocainehy droxybenzoyl hexyl benzoate, 0.1-6wt% of bis-ethylhexyloxyphenol methoxyphenyl triazine, 0.001-0.2wt% of sodium hyaluronate, 0.001-1.0wt% of tetralin methyl pyrimidine carboxylic acid, 0.01-2wt% of LAMINARIA OCHROLEUCA, and effective quantity of cosmetically acceptable carriers. The invention further relates to the preparation method of the composition. The composition disclosed by the invention is prepared based on the principle of the harm of ultraviolet rays to human bodies, has the characteristics of light stability and broad spectrum sunscreen, can improve ultraviolet ray immunity of skin, and can prevent the ultraviolet rays from hurting the human bodies more comprehensively.
Owner:MENTHOLATUM (CHINA) PHARM CO LTD

Pesticidal composition

InactiveUS20080009452A1Effective knock-down actionEffective long-term actionBiocideDead animal preservationFipronilNovaluron
The present invention provides an insecticidal composition comprising of at least one insecticidal compound with effective knock-down action selected from among group (A) comprising of imidacloprid, acetamiprid, thiamethoxam, thiacloprid, nitenpyram, dinotefuran, clothianidin, abamectin, emamectin, emamectin benzoate and fipronil, and at least one insecticidal compound with effective long-term action selected from among group (B) of insect growth regulators comprising of benzoylphenyl urea (BPU) compounds selected from among novaluron, lufenuron, hexaflumuron, triflumuron, diflubenzuron, chlorfluazuron, flufenoxuron, noviflumuron and teflubenzuron. Optionally, said insecticidal composition may further contain excipients and/or additives and/or surface active agents. Further provided is a method for insect control, comprising of applying at least one insecticidal compound with effective knock-down action selected from among group (A) comprising of imidacloprid, acetamiprid, thiamethoxam, thiacloprid, nitenpyram, dinotefuran, clothianidin, abamectin, emamectin, emamectin benzoate and fipronil, and at least one insecticidal compound with effective long-term action selected from among group (B) of insect growth regulators (IGR) comprising of benzoylphenyl urea (BPU) compounds; to a crop, agricultural product, plant matter, animal or locale.
Owner:MAKHTESHIM CHEM WORKS

Self-foaming sun block and preparation method thereof

ActiveCN104688623ADoes not affect the sun protection effectFeel refreshedCosmetic preparationsToilet preparationsALUMINUM STEARATESButanediol
The invention discloses a self-foaming sun block and a preparation method thereof. The self-foaming sun block is prepared from deionized water, glycerinum, butanediol, propylene glycol, methyl parahydroxybenzoats, EDTA-2Na, potassium cetyl phosphate, dicyl polyglycoside, allantoin, xanthan gum, dipotassium glycyrrhizinate, ethylhexyl Methoxycinnamate, C12-15 cholesteryl benzoate, C12-20 alkyl polyglycoside, polydimethylsiloxane, caprylic acid / tricaprin, dicaprylyl carbonate, methylenebis-benzotriazolyl tetramethyl butylphenol, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, a VP / eicosylene copolymer, polyhydroxystearic acid, cyclopentasiloxane, tocopheryl acetate, cyclotetrasiloxane, dimethiconol, propyl p-hydroxybenzoate, aluminum stearate, Novec HFE-7100 and the like. The self-foaming sun block disclosed by the invention is good in sunscreen effect, so that people feel relatively fresh and breathable.
Owner:SHANGHAI ZHONGYI DAILY CHEM CO LTD

Process for preparing raloxifene hydrochloride

Process for preparing raloxifene hydrochloride with a purity greater than 98% and low aluminium content comprising the following stages a) demethylation of 6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene in pyridine and hydrochloric acid to obtain 6-hydroxy2-(4-hydroxyphenyl)benzo[b]thiophene in pyridine hydrochloride, b) acetylation of 6-hydroxy-2-(4hydroxyphonyl)benzo[b]thiophene with an acetylating agent to obtain the corresponding 6-acetoxy-2-(4 acetoxyphenyl)benzo[b]thiophene, c) acylation of 6-acetoxy-2-(4-acetoxyphonyl)benzo[b]thiophene with 4-(2 piperidinoethoxy)benzoylchloride hydrochloride with aluminium trichloride in halogenated solvent to obtain 6-acetoxy-2-(4acetoxyphenyl)-3-[4-(2 piperidinoethoxy)benzoyl]-benzo[b]thiophene, d) hydrolysis of 6-acetoxy-2-(4-acetoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyll benzo[b]thiophene according to the following operating conditions: d1) treatment of 6-acetoxy-2-(4-acetoxyphonyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene with alkaline hydroxide in alcohol solvent, d2) acidification of the product obtained in the preceding stage (d1) with a strong acid, to obtain the corresponding raloxifene salt with the strong acid, characterised in that the strong acid used in stage (d2) is concentrated hydrochloric acid.
Owner:ERREGIERRE

Oil-in-water type sun block and preparation method thereof

The invention discloses oil-in-water type sun block. The oil-in-water type sun block is prepared from, by mass, 1-3% of cetostearyl alcohol, 2-5% of an emulgator, 1-9% of ethylhexyl methoxycinnamate,1-5% of octocrilene, 1-5% of 2-ethylhexyl 4-(dimethylamino)benzoate, 1-8% of diethylaminohydroxybenzoyl hexyl benzoate, 0.5-5% of titanium dioxide, 0.5-3% of aluminium oxide, 1-8% of di(2-ethyl-hexyl)sebacate, 1-8% of C12-15 alcohol benzoate, 1-6% of decamethyl-cyclopentasiloxane, 0.01-0.2% of propyl hydroxybenzoate and 0.1-1% of tocopheryl acetate which comprise a component A; the balance water,0.5-5% of a sun-screening agent and 0.02-0.5% of citric acid which comprise a component B; 0.05-0.2% of methylparaben, 1-10% of polyhydric alcohols and 0.1-2% of sodium stearoyl glutamate which comprise a component C; 0.2-2% of a thickening agent as a component D; 0.01-0.1% of essence and 0.2-1% of a preservative which comprise a component E. The invention further discloses a preparation method ofthe oil-in-water type sun block. The oil-in-water type sun block has a good sunscreen effect, light texture and refreshing and comfortable skin feeling, and can also play a role of concealing and isolating.
Owner:深圳市琉璃光生物科技有限公司

Sunscreen with high sun protection index and preparation method thereof

ActiveCN110051617ATile completeHave a natural affinityCosmetic preparationsToilet preparationsBlack teaButanediol
The invention discloses a sunscreen with high sun protection index and a preparation method thereof. The sunscreen comprises the following raw materials: water, ethyl hexyl methoxycinnamate, bis-ethylhexyphenol methoxyphenyl triazine, dioctyl carbonate, coco-caprylate / caprate, octocrilene, propylene glycol, diethyl hydroxybenzoyl hexyl benzoate, glycerinum, methylene bis-benzotriazolyl tetramethylbutylphenol, decyl glucoside, propylene glycol, xanthan gum, sucrose polystearate, cetachiol stearate, butanediol, ethyl hexyl triazinone, phenoxyethanol, octyl glycol, sodium polyacrylate, tocopherol acetate, bisabolol, sodium stearyl glutamate, polydimethyl alcohol siloxane, sodium hyaluronate, EDTA (ethylene diamine tetraacetic acid) tetrasodium, glucomannan, black tea fungus membrane dispersion, and microcrystalline cellulose. The sun protection and the durability of the sunscreen with high sunscreen index are improved by adopting glucomannan, black tea fungus membrane dispersion and microcrystalline cellulose as a reinforcing system.
Owner:连云港诗碧曼生物科技有限公司

Surface coating agents

Compounds useful as surface coating agents, including compounds of the formula: wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpolymeric core molecule comprising an aromatic group; and Z comprises at least one charged group. The Y core can include an aromatic group such as a benzene radical, the charged groups Z can be independently selected from the organic acids that include sulfonic acid, carboxylic acid, and phosphoric acid, and the photoreactive species of X1 and X2 can independently be aryl ketones, such as those selected from the group acetophenone, benzophenone, anthraquinone, anthrone, and anthrone-like heterocycles, and their substituted derivatives. Examples of such coating agents include 4,5-bis(4-benzoylphenylmethyleneoxy)benzene-1,3-disulfonic acid di(potassium and / or sodium) salt, 2,5-bis(4-benzoylphenylmethyleneoxy)benzene-1,4-disulfonic acid di(potassium and / or sodium) salt (Compound II), and 2,5-bis(4-benzoylphenylmethyleneoxy)benzene-1-sulfonic acid monopotassium and / or monosodium salt.
Owner:SURMODICS INC

Sunscreen composition, preparation method thereof and application of sunscreen composition

PendingCN109908020AGood light stability when used in combinationWon't absorbCosmetic preparationsToilet preparationsAccelerated agingBenzotriazole
The invention discloses a sunscreen composition, a preparation method thereof and an application of the sunscreen composition. The sunscreen composition comprises, by weight, 0.1-10 parts of diethyl-hexyl butylaminyl triazinone, 0.01-10 parts of diethylaminohydroxybenzoyl hexyl benzoate, 0.01-10 parts of diethyl hexoxyphenol methoxyphenyl triazine, 0.01-10 parts of methylene dibenzotriazolidyl tetramethyl butyl phenol, 0.001-2 parts of ectoin and 0.003-2.5 parts of emollients. The preparation method includes the steps: oil-phase mixed liquid preparation; water-phase mixed liquid preparing andmixing. The sunscreen composition can be added into a composition for directly smearing skins, the sunscreen composition can prevent harm of UVA, UVB, HEV and IRA to the skins in a broad spectrum manner, so that the skins cannot be black, red and sunburned, and accelerated ageing and water loss of the skins caused by illumination are prevented.
Owner:MENTHOLATUM (CHINA) PHARM CO LTD

Polymer optical fiber used for luminous fabric, luminous fabric, and manufacturing method for luminous fabric

The invention relates to a polymer optical fiber used for a luminous fabric, the luminous fabric, and a manufacturing method for the luminous fabric. The polymer optical fiber comprises an inner core layer and an outer core layer, wherein the inner core layer consists of polybutylene terephthalate, ETPI (Epoxidized Trans-1,4-polyisoprene), SBS (Styrene Butadiene Styrene), polyethylene acrylate, n-butyl acrylate, polycarbonate, methacryloyloxyethyl silane, vinylsilane, aroyl phosphine oxide, and 2,4-dihydroxy benaophenonel; the outer core layer consists of methacrylic acid n-propyl ester, tetrafluoroethylene, 1,3,5-trimethyltris-1,5-(3,3-trifluoropropyl)-cyclotrisiloxane, vinyltriethoxysilane, methacryloxy propyl trimethoxyl silane, double benzoyl phenyl phosphine oxide, alpha-hydroxyalkyl phenyl ketone, and nanosilicon dioxide. The polymer optical fiber disclosed by the invention is not easy to break, and the luminous fabric made from the polymer optical fiber has the characteristics of high brightness and long service life.
Owner:徐州国宏包装有限公司

Oil-in-water sun-proof product with water-resisting and skin-elasticity-improving functions and preparation method of oil-in-water sun-proof product

The invention belongs to the technical field of cosmetics, and provides an oil-in-water sun-proof product with water-resisting and skin-elasticity-improving functions and a preparation method of the oil-in-water sun-proof product. The oil-in-water sun-proof product is prepared from the following components in parts by weight: 1-3 parts of cetostearyl alcohol, 1-5 parts of polydimethylsiloxane, 1-5parts of decamethylcyclopentasiloxane / cyclohexasiloxane, 3-8 parts of dibutyl adipate, 3-8 parts of propylene glycol dicaprylate / dicaprate, 3-10 parts of titanium dioxide, 5-10 parts of ethylhexyl methoxycinnamate, 1-4 parts of diethylaminohydroxybenzoyl hexyl benzoate, 1-4 parts of ethylhexyl triazone, 1-3 parts of bis-ethylhexyloxyphenol methoxyphenyl triazine, 1-5 parts of octocrilene, 2-10 parts of glycerinum, 2-10 parts of butanediol, 0.1-1 part of triethanolamine, 0.01-0.1 part of an ethylenediaminetetraacetic acid (EDTA) disodium salt, 0.01-2 parts of a thickener, 0.1-2 parts of a preservative, 0.5-2 parts of an emulsifier and 46.5-63.7 parts of water. By adopting the scheme, the problems of poor refreshing property and water resistance of a sun-proof product in the prior art are solved.
Owner:广州微肽生物科技有限公司

Slow release of fragrant compounds in perfumery using 2-benzoyl benzoates, 2-alkanoyl benzoates or alpha-keto esters

The present invention describes a fragrance delivery system which releases fragrant alcohols upon exposure to light. Said system comprises 2-benzoyl benzoates of general formulaewhich can comprise various subtituents R1-R5 as defined in the application and a substituted R* which is the organic part of a fragrant alcohol.In a further embodiment, the present invention describes a fragrance delivery system which releases fragrant aldehydes or ketones and / or fragrant compounds containing an olefin function. This system comprises alpha-keto esters of formulain which R'* and R''* have the meaning as defined in the application and which are generally, in case of R'*, an alkyl group carrying an abstractable hydrogen in gamma-position relative to the keto function and carrying a moiety from which is derived a fragrant compound containing an olefin function, and, in case of R''*, the organic part of a primary or secondary alcohol from which is derived a fragrant aldehyde or ketone.
Owner:FIRMENICH SA

Sunscreen cosmetic

The invention discloses a sunscreen cosmetic, prepared from a composite sunscreen component formed by ethylhexyl methoxycinnamate, diethylamine hydroxybenzoyl hexyl benzoate, titanium dioxide, bis-ethylhexyloxyphenol methoxyphenyl triazine and ethylhexyl triazinone, and other functional ingredients which are reasonably matched. The sunscreen cosmetic has the advantages of good sunscreen effect, noirritation to human skin, and good safety.
Owner:安婕妤化妆品科技股份有限公司

Non-greasy sunscreen with high protection capability and preparation method thereof

The invention discloses a non-greasy sunscreen with high protection capability. The sunscreen comprises, by mass, 0.1-1% of PEG-75 stearate, 0.1-1% of ceteth-20, 0.1-1% of steareth-20, 0.5-1.5% of glyceryl stearate, 0.5-3% of fatty alcohol, 5-10% of C12-15 alcohol benzoate, 0.1-3% of butanediol cocoate, 1-5% of butyl methoxydibenzoylmethane, 0.1-3% of diethylaminohexyl hydroxybenzoyl benzoate, 1-5% of di-ethylhexoxyphenol methoxyphenyltriazine, 1-5% of ethylhexyl salicylate, 1-5% of octocrilene, 5-10% of ethylhexyl methoxycinnamate, 0.1-1% of benzotriazolyl dodecyl p-cresol, 0.05-0.3% of acrylic acid (ester) / C10-30 alcohol sodium acrylate crosslinked polymer, water and the like. The sunscreen is refreshing and non-greasy and has high protection capability and an excellent anti-aging effectat the same time.
Owner:FOSHAN YUNSHANG COSMETICS CO LTD

Sunscreen cream suitable for sensitive skin and preparation method thereof

The invention discloses a sunscreen cream suitable for sensitive skin. The cream is prepared from, by weight, 1-15 parts of an inorganic sunscreen component, 1-30 parts of an organic sunscreen component, 0.1-3 part of sodium polyacrylate, 0.1-5 parts of slagium chloride hectorite, 0.05-2 parts of a xanthan gum, 1-15 parts of a nonionic surfactant, 0.01-5 parts of stearoyl valley sodium citrate and1-20 parts of polyol; the organic sunscreen component is composed of diethylaminohydroxybenzoyl hexyl benzoate, ethylhexyl triazinone, bis-ethylhexyl oxyphenol methoxyphenyl triazine, octyl salicylate and humulizate, and the inorganic sunscreen component consists of titanium dioxide and zinc oxide. The sunscreen cream exhibits a oil and power-in-water system, the sunscreen component is evenly distributed, sunscreen loopholes are effectively reduced and skin irritation is reduced.
Owner:MENTHOLATUM (CHINA) PHARM CO LTD

Method for synthesis of hexa-cata-hexabenzocoronene and derivatives thereof

The invention discloses a method for synthesis of hexa-cata-hexabenzocoronene and derivatives thereof. The method comprises the steps: with 2-bromobenzoyl chloride as a raw material, carrying out a friedel-crafts acylation reaction and a boronation reaction with benzene or a substituent benzene to obtain 2-benzoyl benzeneboronic acid pinacol ester and derivatives thereof, further, carrying out a Suzuki coupling reaction with 1,3,5-tris(bromomethyl)benzene to construct a c-HBC skeleton-1,3,5-tris(((2-benzoyl)phenyl)methyl)benzene and derivatives thereof, and then successively carrying out a reduction reaction, a friedel-crafts reaction and a Scholl cyclization reaction to synthesize the hexa-cata-hexabenzocoronene and the derivatives thereof. The method is mild in reaction conditions and convenient to operate, enables the highest total yield of the products to reach more than or equal to 80%, and can be used for mass production; the synthesized hexa-cata-hexabenzocoronene and the derivatives thereof have no need of alkoxy as a guidance group and a positioning group; and the method is a simple and convenient method for synthesis of the hexa-cata-hexabenzocoronene and the derivatives thereof.
Owner:SHAANXI NORMAL UNIV

Sunscreen lotion and preparation method thereof

The invention belongs to the field of cosmetics, and particularly relates to a sunscreen lotion and a preparation method thereof. The sunscreen lotion provided by the invention belongs to the water-in-oil type sunscreen lotion; meanwhile, a physical sun-screening agent alkyl silicon is used for treating the nano zinc oxide, oil-dispersed nano titanium dioxide, a chemical sun-screening agent ethylhexyl methoxycinnamate, diethylaminohydroxybenzoyl hexyl benzoate, a natural plant sun-screening agent wild soybean seed extract, a sandalwood extract and a lotus leaf extract are mixed and matched, sothat the sunscreen lotion has better safety and stability and small irritation, and the sunscreen performance of the skin is remarkably enhanced. Moreover, due to the addition of the natural plant sun-screening agent, the dosage of the chemical sun-screening agent is reduced, and the natural plant sun-screening agent also has an after-sun repairing effect, has better compatibility with the skin and is good in mildness.
Owner:卡丝生物(广东)科技有限公司

Method for preparing dinitrogen heterocyclooctatetraene

InactiveCN102584725ASimplify the difficulty of synthesis conditionsDifficulty of SimplificationOrganic chemistryBenzoic acidNitrogen
A method for preparing dinitrogen heterocyclooctatetraene comprises the following steps of (1) conducting friedel-craft reaction with anhydride and aromatic compounds serving as reaction raw materials, and preparing substituted benzene formoxyl benzoic acid compounds; (2) preparing benzoyl chloride by using substituted benzene formoxyl benzoic acid under the condition of chlorination reagent, and using reaction of sodium azide and the benzoyl chloride at -10-50 DEG C to prepare benzoyl azide compounds; and (3) enabling the benzoyl azide compounds to conduct ring gathering reaction under an acidity system at 20-120 DEG C, and preparing the dinitrogen heterocyclooctatetraene. The method for preparing the dinitrogen heterocyclooctatetraene is low in price of used raw materials and soft in reaction condition, greatly reduces cost for prepare the dinitrogen heterocyclooctatetraene, can be used in the fields of photoelectrical materials, medicines and the like.
Owner:QINGDAO INST OF BIOENERGY & BIOPROCESS TECH CHINESE ACADEMY OF SCI

Method for synthesizing anthraquinone

The invention discloses a method for synthesizing anthraquinone, which belongs to the technical field of preparation of organic compounds. In the method, by using acidic ionic liquid a solvent and a catalyst and by heating under a pressure lower than the atmosphere, o-benzoylbenzoic acid is subjected to cyclodehydration, an anthraquinone product is obtained by sublimation and collection, the further purification of the product is not needed, and the ionic liquid can be repeatedly used for many times. In the invention, the used amount of the ionic liquid is 4 to 8 times the mass of o-benzoylbenzoic acid, the reaction temperature is 120 to 180 DEG C, the reaction time is 3 to 10 hours, and the pressure is 5 to 50mmHg. Due to the characteristics of the ionic liquid, three industrial wastes, namely waste gas, waste water and waste residue, are not produced in a reaction process, so the reaction process is a green chemical process; and thus, the pollution to the environment is reduced to the maximum degree. The method has the advantages of simple process, high yield, environment friendliness and low cost, and is suitable for industrial production.
Owner:LIAONING UNIVERSITY OF PETROLEUM AND CHEMICAL TECHNOLOGY

Application of 3-(benzoyl phenyl) propionic acid derivative in treatment of connexin CX31 mediated skin diseases

The invention provides an application of a 3-[[2-[3-oxo-(1, 2-benzisoxazole-6-yl) methoxyl]-5-[(2-hydroxyl-4-cyclopentoxyl benzoyl)] phenyl] propionic acid (compound I) in preparation for treatment of connexin CX31 mediated skin disease. The connexin CX31 mediated skin disease comprises erythrokeratodermia variabilis or psoriasis. The pharmacological experiment proves that a low-dose group and a high-dose group of the compound I can remarkably reduce skin damage degree of a psoriasis animal sample; the content of TNF-alpha in murine serum can be restrained by the low-dose group of the compound I, then inflammatory cell infiltration is restrained, the inflammatory response is relieved, and the compound I has good psoriasis treatment effect and can be used for treating the connexin CX31 mediated skin disease.
Owner:TIANJIN INT JOINT ACADEMY OF BIOTECH & MEDICINE +1

Fullerene-containing biological sunscreen composition and aerosol

ActiveCN110613619ASootheCalm downCosmetic preparationsToilet preparationsDiseaseEthylhexyl triazone
The invention belongs to the technical field of sunscreen and skin care products, in particular to a biological sunscreen composition containing fullerene and an aerosol. The biological sunscreen composition of the invention comprises the following preparation raw materials: fullerene, glucosylrutin, isoamyl p-methoxycinnamate, polysiloxane-15, ethylhexyl triazone, diethylaminohydroxybenzoyl hexylbenzoate and bis ethyl hexyl oxyphenolmethoxyphenyl triazine. The raw material components of the biological sunscreen composition of the invention are green, environment-friendly, safe and harmless,and the whole band of UVB, UVA, visible light and IRA can be comprehensively and effectively protected through the coordination of the raw materials, so as to effectively prevent various skin problemssuch as skin diseases, skin injuries and the like induced by sunlight, and better protect people's health and beautiful life.
Owner:中山市天图精细化工有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products