34results about How to "Reduce chemical toxicity" patented technology

The present invention discloses a graphene fiber and a method of manufacturing the same. The graphene fiber is manufactured by oxidizing graphite, dispersing, spinning, drying and heat treatment, and has a diameter less than 100 μm, a ratio of length to diameter greater than 10, and a ratio of carbon to oxygen greater than 5. The graphene fiber is formed of a plurality of graphene sheets, which envelop an axis and are coaxially stacked one by one from the axis. The thickness of the graphene sheet is less than 3 nm, and chemical bonds are formed to tightly bond the graphene sheets to exhibit excellent mechanical and thermally / electrically conductive properties. The method of the present invention is implemented by simple steps so as to greatly reduce poisonous chemicals possibly generated in the manufacturing environment, thereby improving the safety of manufacturing and reducing the whole processing time and cost.

The invention discloses a high-strength soluble nanoscale particle temporary plugging agent. The high-strength soluble nanoscale particle temporary plugging agent comprises, by weight, 18-30 parts of sodium chloride, 0.05-1.5 parts of dispersing agent, 0.2-0.6 part of tackifier, 10-25g of solid calcium chloride and 80-120 parts of solvent water. The high-strength soluble nanoscale particle temporary plugging agent is prepared by adding the solid calcium chloride into a mixed solution dissolved with the dispersing agent, the sodium chloride and the tackifier and performing high-speed stirring. The high-strength soluble nanoscale particle temporary plugging agent has the advantages that the temporary plugging agent uses nanoscale NaCl crystals in normal distribution in the particle size range of 0.25-22.81 micrometers as the main constraint to form an organic whole in a spatial network structure formed in natural polymer and an aqueous solution, and the temporary plugging agent is good in dispersity, good in plugging effect, suitable for making cracks and micro-seams, and the like.

The invention provides an environment-friendly non-chlorine-salt snow melting and deicing agent and a preparation method thereof, and belongs to the field of snow melting and deicing. The environment-friendly non-chlorine-salt snow melting and deicing agent is characterized by comprising the following raw materials in percentage by weight: 60-90 percent of main solvent, 2-20 percent of wetting cosolvent and 2-20 percent of corrosion inhibitor, wherein the main solvent is prepared from 60-90 percent by weight of formate and 10-40 percent by weight of sodium metasilicate; the wetting cosolvent is prepared from 40 percent by weight of sodium borate or calcium nitrate and 60 percent by weight of urea or ammonium carbonate; the corrosion inhibitor is prepared from 60 percent by weight of sodium gluconate and 40 percent by weight of zinc sulfate. According to the environment-friendly non-chlorine-salt snow melting and deicing agent, the common problems of high corrosivity, serious impact on soil structures and the like of common inorganic chlorine salt snow melting agents can be effectively solved; after being used, the environment-friendly non-chlorine-salt snow melting and deicing agent can be naturally decomposed under the natural environment, and the cost of the non-chlorine-salt snow melting and deicing agent is lower than that of other organic salt (like acetates including potassium acetate, calcium magnesium acetate and the like) snow melting and deicing agents; therefore, the environment-friendly non-chlorine-salt snow melting and deicing agent is suitable for being used in places like domestic and overseas roads, airport pavements and streets, and has wide popularization and application prospects.

The invention relates to a deep oxidization water treatment method and a deep oxidization water treatment device; the deep oxidization water treatment method and the deep oxidization water treatment device are formed by utilizing a high dissolved ozone amount air dissolution technology and a micro-bubble aeration technology in combination with use of ozone, ultraviolet photocatalysis and a photosensitive chemical catalyst; dissolved oxygen and ozone are utilized; furthermore, a large number of hydroxyl radicals excited by ultraviolet photocatalysis chemical reaction can participate in the so-called oxidization chain reaction; and a deep oxidization technology is higher in oxidation capacity and rapider in oxidization speed. The deep oxidization water treatment method and the deep oxidization water treatment device disclosed by the invention are not only applied to sterilizing ordinary drinking water but also applied to oxidizing and degrading organic pollutants, which are difficult to biodegrade and high in concentration and toxicity; and the deep oxidization water treatment method and the deep oxidization water treatment device not only can be used as an independent sewage treatment method and an independent sewage treatment device but also can be used as a pre-processing method for reducing the concentration and the toxicity in sewage used with the existing biodegradable water treatment technological method and equipment in a matched manner.

The invention belongs to the field of freezing and provides a cell vitrification freezing liquid and a freezing method. The freezing liquid comprises a washing liquid, an equilibrium liquid and a vitrifying liquid. With the freezing fluid, the action time in the equilibrium liquid and the vitrifying liquid is shortened, and chemical toxicity of an osmosis protective agent is reduced. In addition,the operation is simple, and the cell survival rate is high.

The invention relates to a silsesquioxane-modified hybrid phenolic resin, and a preparation method and an application thereof, and belongs to the field of high-performance resin matrix composite materials. The silsesquioxane-modified hybrid phenolic resin provided by the embodiment of the invention is a hybrid phenolic resin cured product with a POSS molecule as a chemical crosslinking point, formed through reacting the POSS molecule represented by formula (1) with phenolic resin, and the addition of a POSS hybrid molecule strengthens nanoparticles, so the initial maximum decomposition temperature of the resin is improved to about 580 DEG C from 450 DEG C of pure resin, the residual weight is increased to about 65% from 58%, and the ablation resistance of the material is remarkably improved; and the POSS-modified hybrid phenolic resin provided by the invention has potential application prospects in the field of aerospacecraft resin-based advanced thermal protection materials.

The invention belongs to the biomedicine technical field, relating to a cell pairing and fusion chip. The cell pairing and fusion chip comprises a chip body provided with a hollow and closed cell fusion chamber, wherein a cell trap consisting of two symmetrical semilunar banks is arranged at the bottom plate of the cell fusion chamber. Each bank comprises a short end and a long end; the projecting arc surfaces of the two semilunar banks face to each other, of which the short ends form a first opening, while the long ends form a second opening; the bottom part of the semilunar bank is fixed on the bottom plate; a definite interval exists between the top part of the semilunar bank and the top plate of cell fusion chamber; and the first sampling hole corresponding to the first opening direction of the cell trap and the second sampling hole corresponding to the second opening direction of the cell trap are arranged along the diagonal direction of the cell fusion chamber. The chip with simple and ingenious structure can extremely improve cell paring rate and fusion rate, reduce the chemical poisoning effect of inducer to cell, and be operated easily.

The present invention relates to blood vessel storing liquid for fast vitrifying and cryogenically storing body blood vessel, artificial blood vessel and tissue engineering blood vessel and the corresponding storage method. The blood vessel vitrifying and storing liquid is compounded through diluting polysaccharose and mycose with M199 diluent to obtain mixed solution of 20-35 % and 15-25 % concentration separately; diluting vinyl glycol and vinyl alcohol with the mixed solution to mixed liquid of 20 % concentration; and adding azone as high penetrant in 0.5-1 % to form the blood vessel vitrifying and storing liquid, into which, 0.001-0.005 % of cationic surfactant may be also added. Blood vessel is thrown into the vitrifying and storing liquid inside some plastic bag at room temperature, and the sealed bag is thrown into liquid nitrogen for cryogenical storing. The cryogenically stored blood vessel may be defrosted via taking out the bag from liquid nitrogen and soaking in water bath at 22-25 deg.c for 15 sec.

The invention provides a method for fluorinating volatilizing recovery of uranium by using nitrogen trifluoride as a fluorinating agent. The method comprises: (1) removing air and water in a reactor,wherein the reactor is filled with the molten salt of a uranium-containing compound, or with a mixture containing elemental uranium, or with one or a plurality of uranium compounds, the uranium content in the molten salt of the uranium-containing compound is 0.01-30%, and the mixture containing elemental uranium is a mixture comprising elemental uranium and a nuclear fission product and / or a metalalloy; and (2) heating the reactor in stages, introducing a mixed gas of nitrogen trifluoride and an inert gas, carrying out a reaction, and recovering the reaction product, wherein the volume fraction of the nitrogen trifluoride in the mixed gas is 5-50%, heating is performed from a room temperature to 200-250 DEG C and first thermal insulation is performed in the first stage, and in the secondstage, heating is performed from the ending temperature of the first stage to 500-750 DEG C, and second thermal insulation is performed. According to the present invention, with the method, the safe,stable and long-term operation of the equipment can be achieved.

The invention discloses shrinkage-method sequential vitrification refrigerating fluid with an impervious protecting agent for oocyte and a usage method thereof. The sequential vitrification refrigerating fluid comprises shrinkage fluid, equilibrium fluid and vitrification fluid, wherein the shrinkage fluid is impervious protecting agent for dehydrating a cell. The shrinkage-method sequential vitrification refrigerating fluid has the advantages that (1), before entering the equilibrium fluid, the cell is firstly subjected to pretreatment by using the impervious protecting agent to be dehydrated; the acting time in the equilibrium fluid can be shortened; the chemical toxicity of the pervious protecting agent is decreased; (2), the impervious protecting agent is subjected to the pretreatment, so that the stability of the cytomembrane of an ovum can be improved; the oven is enabled to be more tolerant to an osmotic injury; the improvement of the survival rate of a resurgent oven is facilitated; (3), operators of different proficiency levels can all obtain a quite stable high survival rate; the long-time and large-sample-quantity technical training cannot need to be carried out before clinical application; (4), the result is stable; the operation is simple; the clinical wide popularization of a vitrification refrigeration technique for a human oocyte is greatly facilitated.

The invention discloses a preparation method of a high-strength soluble nano-scale particle temporary plugging agent for fracturing, wherein the preparation method comprises the concrete steps of adding a calcium chloride solid into a mixed solution dissolved with a dispersant, sodium chloride and a tackifier and carrying out high-speed stirring for 0.1-1.0 h, wherein sodium chloride in the mixed solution is close to saturation, and the speed of the high-speed stirring is 200-1000 rpm. The preparation method of the temporary plugging agent is simple and easy to operate; the dispersant and xanthan gum are added to a sodium chloride solution close to the saturation and are compounded with finally added calcium chloride to prepare the temporary plugging agent; nanoscale NaCl crystals showing normal distribution in a certain range of particle size and used as a main body are bound in a space network structure formed by natural macromolecules in an aqueous solution to form an organic whole, so that the temporary plugging agent has the advantages of good dispersion and good plugging effect, and is suitable for small seams, micro seams and the like.

The invention discloses a molten salt deoxidizing method using nitrogen trifluoride as a fluorinating agent. The molten salt deoxidizing method comprises the following steps: (1) removing air and water in a reactor, wherein the reactor is filled with a molten salt; (2) heating the reactor until the molten salt is completely melted, introducing a mixed gas of nitrogen trifluoride and an inert gas,and performing a reaction for 12-72 h, wherein the volume fraction of the nitrogen trifluoride in the mixed gas of nitrogen trifluoride and the inert gas is 5-50%. The method using the nitrogen trifluoride instead of hydrogen fluoride as the fluorinating agent overcomes the defects of poor safety, severe corrosion and short service life of a the reactor, complexity in operation and high cost in the prior art; and the nitrogen trifluoride has a low chemical toxicity, and has stable properties at room temperature.

The invention relates to the technical field of poultry feed and in particular relates to fattening feed for fattening adult sheep of a high-density livestock farm. The feed is prepared from coarse feed, concentrated feed and an additive; specifically, the coarse feed is prepared from sweet potato leaves, sorghum sudanense, alfalfa, trifolium repens and festuca arundinacea; the concentrated feed is prepared from millet, wheat bran, konjac flour and potato powder; the feed additive is prepared from an adaptive-period additive, a transitional-period additive and a fattening-period additive. The fattening feed provided by the invention is specially designed according to growth habits and various functions of the adult sheep; the fattening feed has a balanced nutrient proportion and a good fattening effect; the reward of the feed is high and the fattening time of the adult sheep can be remarkably shortened.

The invention belongs to the field of preparation of pharmaceutical intermediates, and particularly relates to a preparation method of decarbamoyl cefuroxime. The method comprises steps as follows: 7-aminocephalosporanic acid as a mother nucleus for synthesis of decarbamoyl cefuroxime is subjected to esterolysis, a product is then subjected to condensation reaction with an acyl chloride liquor of2-methoxyimino-2-furyl acetic acid ammonium, a reaction product is left to stand and subjected to crystallization by ethanol / hydrochloric acid, washing, suction filtration and drying are performed, and the product decarbamoyl cefuroxime is obtained. According to the method, 7-aminocephalosporanic acid is taken as the raw material and crystalized by ethanol and is safe and low in toxicity, and theproduction cycle is shortened; meanwhile, reaction conditions of the method are mild, and industrial production is facilitated.

The invention belongs to the technical field of biology and provides a 125I-labeled Caerin polypeptide and an application thereof to preparation of a drug for treating tumors and particularly benign and malignant tumors relevant to HPV infection. The 125I-labeled Caerin polypeptide provided by the invention is prepared by using an optimized direct labeling method, and the preparation method is simple and convenient to operate, high in labeling rate, short in reaction time and good in in-vivo and in-vitro stability. The 125I-labeled polypeptide prepared after a Caerin polypeptide is 125I-labeled has a remarkable effect on inhibiting tumor cells and is capable of remarkably improving the treatment effect of the Caerin polypeptide, reducing the use dosage of the Caerin polypeptide and reducing the preparation cost and chemical toxicity of the drug for treating the tumors and particularly tumors relevant to HPV infection, so that the treatment cost of the tumors is reduced, and the medication safety of the tumors is improved.

The invention relates to a high silica fiber reinforced reactive silsesquioxane modified hybrid phenolic composite material and a preparation method thereof. Hybrid phenolic resin is prepared from POSS modified phenolic resin with a silicon hydroxyl structure, high silica fiber is impregnated with the hybrid phenolic resin to prepare a prepreg, and the fiber reinforced composite material is prepared through hot press molding. POSS and phenolic resin are subjected to a cross-linking reaction, and introduction of POSS hybrid molecules plays a role in nanoparticle reinforcement. The mass loss ofthe hybrid resin is 5%, the temperature is increased to 385.5 DEG C from 306.6 DEG C, and the heat resistance of the material is improved. The linear ablation rate of the fiber reinforced composite material is reduced from 0.191 mm / s to 0.163 mm / s, the mass ablation rate is reduced from 0.0703 g / s to 0.0643 g / s, and the ablation resistance of the material is remarkably improved. The high silica fiber reinforced POSS modified phenolic resin-based composite material provided by the invention has a wide application prospect in the fields of aerospace craft resin-based advanced thermal protectionmaterials and engine exhaust nozzle thermal insulation materials.

The invention relates to the technical field of poultry feeds and in particular to a special fattening fertilizer designed for obsolete sheep. The feed is composed of a coarse feed, a refined feed and an additive component. In particular, the coarse feed is composed of Kochia scoparia, Silene conoidea L., plantaginaceae Plantago major, burclover and zoysia japonica; the refined feed is composed of sticky rice, maize flour and potato powder; and the feed additive is composed of a lactobacillus brevis fermenting liquid, ethylene diamine tetraacetic acid and alkalized green plums. The fattening fertilizer provided by the invention is specially designed according to the growth habit and functions of the obsolete sheep, is balanced in nutritional proportion, good in fattening fertilizer and high in feed conversion, and the fattening time of the obsolete sheep can be obviously shortened.

The invention provides a method for separating uranium and neptunium through a fluorinated volatilization technology. The method comprises the following steps that (1), air and water in a reactor are removed, the reactor is filled with a mixture A or a mixture B, the mixture A comprises a substance containing uranium elements and neptunium elements, the mixture B comprises a substance containing uranium elements, a substance containing neptunium elements and fused salt, the substance containing uranium elements comprises uranium elementary substance and / or uranium compound; and the substance containing neptunium elements is neptunium elementary substance and / or neptunium compound; (2), reaction products containing uranium elements are recycled; and (3) the residual product after the uranium elements are recycled is cooled to 350-600 DEG C, mixed gas of fluorine gas and inert gas is introduced, a reaction product containing neptunium elements is recycled; and the reaction temperature in the step 2 is higher than that in the step 3. The method has the advantages that the reaction speed is high, the conversion rate of uranium and neptunium is large, the separation efficiency of uranium and neptunium is high, side reactions are few, the separation selectivity is good, and serialization is easy.

The invention discloses a preparation method of artificial xenogeneic skin. In the method, the intima of the blood vessel is obtained after processing the pig thoracic aorta, and then passed through 1M sodium chloride solution, 10mg / mL sodium lauryl sulfate solution and 2.5mg / mL of trypsin solution, rinsed, and finally cut into a suitable size according to clinical needs, and sterilized by electron beams, the artificial xenogeneic skin was obtained. The artificial skin of the invention has rich sources of raw materials, short production period, long storage time and low price, and has great potential for clinical application.

The invention belongs to the biomedicine technical field, relating to a cell pairing and fusion chip. The cell pairing and fusion chip comprises a chip body provided with a hollow and closed cell fusion chamber, wherein a cell trap consisting of two symmetrical semilunar banks is arranged at the bottom plate of the cell fusion chamber. Each bank comprises a short end and a long end; the projecting arc surfaces of the two semilunar banks face to each other, of which the short ends form a first opening, while the long ends form a second opening; the bottom part of the semilunar bank is fixed onthe bottom plate; a definite interval exists between the top part of the semilunar bank and the top plate of cell fusion chamber; and the first sampling hole corresponding to the first opening direction of the cell trap and the second sampling hole corresponding to the second opening direction of the cell trap are arranged along the diagonal direction of the cell fusion chamber. The chip with simple and ingenious structure can extremely improve cell paring rate and fusion rate, reduce the chemical poisoning effect of inducer to cell, and be operated easily.

The invention relates to a targeted adhesion chitosan material and application thereof. Under the action of dual-functional (N-hydroxysuccinimide / azide) light-sensitive cross-linking agent, through grafting reaction by UV photochemical activation, cell adhesion peptide is grafted on the chitosan to obtain the safe (non-toxic and degradable) targeted adhesion chitosan material which is characterized in that the biocompatibility is good, the biological function is good and the dissolubility under faintly acid condition is obviously enhanced. Through self assembling method, the targeted adhesion chitosan material can form stable nano particles with grain size of 100mm-500mm and surface positive charge of 10mV-30mV and the stable nano particles can be used as the carriers of DNA (20bp-10kb) or RNA [dsRNA (500-700bp), small RNA (siRNA, microRNA or shRNA)] and other nucleic acid drugs. When the carried DNA or RNA is protected from being degraded by the corresponding enzyme, the carried DNA or RNA can target at the overexpressed integrin receptors on the surface of tumor cells, so cell transfection and release in cells are facilitated to cure tumors.

The invention discloses a method for fluorinating and separating uranium and molybdenum by using nitrogen trifluoride as a fluorinating agent. A mixture A composed of substances containing uranium elements, a substance containing molybdenum elements, and a molten salt; the content of the uranium element is greater than or equal to 10ppb; and / or, the content of the molybdenum element is greater than or equal to 10ppb; 2) Heating the reactor in stages, the first stage is heated from room temperature to 250-450°C, and a mixed gas of nitrogen trifluoride and inert gas is introduced to recover the reaction product containing molybdenum; 3) The second stage consists of At the end of the first stage, the temperature is heated to 450-850°C, and the mixed gas is continuously introduced to recover the reaction product containing uranium. The method provided by the invention can not only realize efficient separation of U-Mo, but also realize stable long-term operation of equipment.

The present invention relates to blood vessel storing liquid for fast vitrifying and cryogenically storing body blood vessel, artificial blood vessel and tissue engineering blood vessel and the corresponding storage method. The blood vessel vitrifying and storing liquid is compounded through diluting polysaccharose and mycose with M199 diluent to obtain mixed solution of 20-35 % and 15-25 % concentration separately; diluting vinyl glycol and vinyl alcohol with the mixed solution to mixed liquid of 20 % concentration; and adding azone as high penetrant in 0.5-1 % to form the blood vessel vitrifying and storing liquid, into which, 0.001-0.005 % of cationic surfactant may be also added. Blood vessel is thrown into the vitrifying and storing liquid inside some plastic bag at room temperature, and the sealed bag is thrown into liquid nitrogen for cryogenical storing. The cryogenically stored blood vessel may be defrosted via taking out the bag from liquid nitrogen and soaking in water bath at 22-25 deg.c for 15 sec.