The invention discloses large-section aluminum-containing hot-rolled H-shaped steel and a manufacturing method thereof. Chemical components of the hot-rolled H-shaped steel comprise, by weight percent, 0.11-0.14% of C, 0.18-0.25% of Si, 1.40-1.50% of Mn, smaller than or equal to 0.025% of P, smaller than or equal to 0.008% of S, 0.040-0.050% of V, 0.012-0.02% of Ti, 0.040-0.050% of Al and the balance iron and trace impurity. The manufacturing method of the steel comprises the steps of molten iron pre-desulfuration, converter smelting, LF refining, near-net-shape beam bank continuous casting and rolling. According to the steel and the method, by means of vanadium-titanium composite microalloying, meanwhile, an aluminum element is used in cooperation, the refined crystalline strengthening and dispersion strengthening effect is achieved, and the comprehensive mechanical performance of the large-section H-shaped steel is improved. In the production process, the beam blank single-point flange non-equilibrium full-protection continuous casting technology is adopted, the cleanness degree of the molten steel is controlled strictly, scaffolding of a water opening is reduced, the inclusion content is low, the low-temperature impact performance of rolled materials is stable, and the yield is high.