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76results about How to "Improve the modification rate" patented technology

Disaster recovery processing method and apparatus and storage unit for the same

A technique capable of constructing a disaster recovery system reduced in performance degradation of a primary system is provided. The technique includes a step of conducting synchronous writing of log information into a secondary storage subsystem in a secondary system when a write request received from a host computer is a write request of log information, a step of temporarily storing a write request and conducting asynchronous writing into the secondary storage subsystem when the received write request is a write request of database data or status information, a step of modifying log information, data in a database area, and status information in the secondary storage subsystem according to contents of a write request received from a primary storage subsystem, and a step of recovering the database area according to contents of log information in a location indicated by the status information.
Owner:HITACHI LTD +1

Ethylene/alpha-olefin copolymer, method for producing the same, and use thereof

The present invention intends to provide an ethylene / alpha-olefin copolymer of specific structure, exhibiting excellent performance as a lubricant oil additive, capable of having various functional groups in high ratio, and serviceable as raw material for various solubilizing agents. The ethylene / alpha-olefin copolymer of the present invention is composed of ethylene and an alpha-olefin having 3 to 10 carbon atoms, and characterized by specific characteristics.
Owner:MITSUI CHEM INC

Bottom surface-integrated wear-resistant fluorosilicone-based super-amphiphobic coating, and preparation method and application thereof

The invention discloses a bottom surface-integrated wear-resistant fluorosilicone-based super-amphiphobic coating, and a preparation method and application thereof. The preparation method comprises the following steps: 1) performing synergistic modification treatment on two or more nanoparticles to obtain modified blended particles; 2) adding the blended modified particles into a dispersing solvent, performing ultrasonic dispersion for 1 to 2 hours and then mechanically stirring; 3) adding a certain amount of tert-butyl acetate into fluoro-siloxane resin and performing shearing dispersion to obtain substrate material emulsion; 4) mixing the blended modified particle turbid liquid in the step 2 and the substrate material emulsion in the step 3, adding a coupling agent, heating, stirring anddispersing, and performing dispersion by a high-speed shearing dispersing machine to obtain super-amphiphobic coating; and 5) stirring the super-amphiphobic coating uniformly, spray-coating the surface of an object with the super-amphiphobic coating and drying at room temperature for 10 to 30 minutes to successfully prepare the wear-resistant integrated super-amphiphobic coating. The wear-resistant super-amphiphobic organic-inorganic hybrid coating is obtained by connecting a fluorine-silicon substrate and the blended modified particles through chemical grafting copolymerization reaction.
Owner:ELECTRIC POWER RESEARCH INSTITUTE OF STATE GRID SHANDONG ELECTRIC POWER COMPANY +1

Process for producing bisphenol A

InactiveUS7129382B2Suppressing deterioration of catalytic activityExtended service lifeOrganic compound preparationOrganic chemistry methodsPhenolIon-exchange resin
There is disclosed a process for producing bisphenol A by subjecting phenol and acetone to condensation reaction in the presence of a catalyst composed of an acid type ion exchange resin which is modified in part with a sulfur-containing amine compound, wherein the ion exchange resin having a modification rate of 10 to less than 20 mol % is used for a methanol concentration in acetone of lower than 250 ppm by weight, and the ion exchange resin having a modification rate of 20 to 65 mol % is used for a methanol concentration in acetone of 250 to 8000 ppm by weight. The above process is capable of producing bisphenol A at high conversion and selectivity by suppressing deterioration of catalytic activity due to methanol as an impurity in acetone.
Owner:IDEMITSU KOSAN CO LTD

Method for preparing nano coating additive emulsion with flame-retarding characteristic

InactiveCN1978556ANo obvious interfaceGood compatibilityCoatingsEmulsionInorganic particle
This invention is related to a kind of nano additive emulsion to coatings characteristic of fire retardant and its preparation method. The said method is that using the modified inorganic particles as 'seeds'in the water solution, adding wetting agent, buffering agent and functioned styrene monomer, initiating the polyreaction system, and then obtaining inorganic and organic nano composite emulsion. The said preparation method used in this invention is universal. The said composite has characteristic of fire retardant and can be used as an additive to coatings to improve the function and performance of the coatings and enhance the added value of the products.
Owner:CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI

Cysteine-hyaluronic acid conjugate prepared through freeze drying and thiol-ene click chemistry, synthesis method and applications thereof

The present invention discloses a cysteine functionalized hyaluronic acid conjugate prepared through freeze drying and thiol-ene click chemistry, and a synthesis method thereof, and discloses applications of the hyaluronic acid conjugate in preparation of an injectable in-situ hydrogel, and applications of the formed injectable in-situ hydrogel in islet cell culture and insulin secretion. According to the present invention, a series of cysteine functionalized hyaluronic acid conjugates having different modification rates and stable ether bonds are obtained through freeze drying and thiol-ene click chemistry, wherein the cysteine functionalized hyaluronic acid conjugate has the thiol active group, such that the further functionalized modification can be performed; and the hyaluronic acid conjugates having different modification rates and the polyethylene glycol conjugate can be subjected to the oxo ester-mediated natural chemical link reaction to obtain the an injectable in-situ formed hydrogel, wherein the obtained hydrogel has the good rheological property, the free thiol group can increase the cell adhesion of the hyaluronic acid and can be adopted as the cell scaffold material so as to be used in the islet cell culture and the insulin secretion stimulation, and the broad biomedical prospects are provided.
Owner:HAINAN UNIVERSITY

Monofunctional branched polyethyleneglycol

The invention discloses a monofunctional branched polyethyleneglycol. The general formula of the monofunctional branched polyethyleneglycol is disclosed as Formula (1), wherein X1 and X2 are respectively an alkyl group with 1-20 carbon atoms; n1 and n2 are respectively a whole number ranging from 1 to 1000; n3 is a whole number ranging from 11 to 1000; L1 and L2 are respectively a linking group capable of existing stably under illumination, enzyme, acidic or alkaline conditions; p is 0 or 1; R1 is a hydrogen atom or alkyl group with 1-20 carbon atoms; and R is a functional group. The monofunctional branched polyethyleneglycol overcomes the defects of traditional multiarm polyethyleneglycol in drug modification application, can modify biologically relevant substances under mild conditions, and has the advantages of high modification rate, fewer byproducts, high activity retentivity and the like.
Owner:XIAMEN SINOPEG BIOTECH

HPLC (high-performance liquid chromatography) chromatographic column packing modification method

The invention relates to a HPLC (high-performance liquid chromatography) chromatographic column packing modification method. The method includes: putting HPLC chromatographic column packing in diazonium resin solution, stirring for reaction for 2-4h at the room temperature in a dark environment, carrying out centrifugal separation, washing and drying products, and performing exposure treatment under ultraviolet light for 10-20min. By adoption of photosensitive macromolecular diazonium resin as surface modifier, hydrogen-bonding interaction between the diazonium resin and surface silanol groups of silicon dioxide microspheres is converted into covalent bonding interaction by means of photo-crosslinking reaction, and accordingly hydrophobic groups can be introduced to the surface of the microsphere, and the modified chromatographic column packing has excellent separation effects.
Owner:QINGDAO UNIV

Three-arm polyethylene glycol derivative and preparation method thereof

The invention provides a three-arm polyethylene glycol derivative with a structure as shown in formula I. The three-arm polyethylene glycol derivative has a single functional group which is positioned on the center of a high polymer framework, and a product obtained by modifying a protein drug with the three-arm polyethylene glycol derivative is simple in structure, and convenient to separate and purify in the later stage. Besides, the three-arm polyethylene glycol derivative provided by the invention can perform site-specific modification on biological active molecules under a relatively gentle condition, is convenient to transform the functional group, relatively high in modification rate and capable of improving the activity of the biological drug and the in-vitro stability of the biological drug. Meanwhile, the three-arm polyethylene glycol derivative is stable in quality, and has stable repeatability on the modified biological drug. The invention further provides a preparation method of the three-arm polyethylene glycol derivative; an initiator with the structure as shown in formula II is adopted to process after performing ring opening polymerization on epoxy ethane to obtain the three-arm polyethylene glycol derivative.
Owner:吕常海

Polyethylene glycol modified tumor angiogenesis inhibitor HM-1 and application thereof

The invention discloses a polyethylene glycol modified tumor angiogenesis inhibitor HM-1 and application thereof, and belongs to the field of polypeptide drugs. The peptide sequence adopted in the polyethylene glycol modified tumor angiogenesis inhibitor HM-1 is mPEG-Arg-Gly-Ala-Asp-Arg-Ala-Gly-Gly-Gly-Gly-Arg-Gly-Asp, wherein mPEG is mPEG-SC, mPEG2-NHS, mPEG-ALD or mPEG-bALD, and the molecular weight range is 500 to 40000. The polypeptide modified by polyethylene glycol has the capacity of restraining endothelial cell migration and integrin affinity and binding, and can be applied to prevention and treatment of tumours, various phlegmonosis and neovascular eye diseases. The polyethylene glycol modified tumor angiogenesis inhibitor is prepared through an artificial synthesis method.
Owner:NANJING ANJI BIOLOGICAL TECH CO LTD

Nanoreactor as well as preparation method and application thereof

The invention discloses a nanoreactor as well as a preparation method and application thereof. The nanoreactor comprises core-shell nanoparticles, manganese dioxide and a targeting ligand, wherein the surfaces of the core-shell nanoparticles are coated with the manganese dioxide and the targeting ligand layer by layer; the core-shell nanoparticles are formed by a metal organic framework, a photosensitizer, glucose oxidase and a polylactic acid-glycolic acid copolymer nano core wrapped by the metal organic framework, and the metal organic framework is formed by tannic acid and iron through coordination; and the targeting ligand is one or more of hyaluronic acid, synthetic polypeptide, a folic acid modified hydrophilic polymer and a nucleic acid aptamer. The nanoreactor can actively target to tumor cells, catalyzes oxygen production to realize in-situ oxygen supply of tumors, removes glutathione and ATP so as to inhibit and overcome tolerance, and enhances the photodynamic therapy efficiency. The preparation method is simple and effective, effectively avoids the toxicity of a carrier, is high in drug loading capacity and modification rate, and can be applied to preparation of tumor targeting drugs.
Owner:湖南省人民医院

Modified conjugated diene-based polymer and method for preparing the same

The present invention provides a modified conjugated diene-based polymer which includes a functional group derived from a substituted styrene-based compound and a functional group derived from an aminosilane-based compound, a method for preparing the same, and a rubber composition including the same. The modified conjugated diene-based polymer includes the functional group derived from an aminosilane-based compound of Formula 1 and a functional group derived from a substituted styrene-based compound of Formula 2 at both terminals of a main chain, and thus, shows a high modification ratio. When applying the polymer in a rubber composition, excellent affinity with a filler may be shown, and as a result, agglomeration of a filler in the rubber composition may be prevented, and the dispersibility of the filler may be increased, thereby improving the processability of the rubber composition.
Owner:LG CHEM LTD

Polyolefin polymer having polar group, method for production thereof, and water dispersion material and mold release agent composition

Disclosed are: a polyolefin polymer having a polar group represented by the general formula (i), which is produced by modifying, with a high degree of modification rate, a double bond in a polymer that has the double bond at one terminal, at both terminals, or in the inside of its polymer chain and is produced by a known method; a method for producing the polyolefin polymer; and a water dispersionmaterial and a mold release agent composition each comprising the polyolefin polymer. (i) wherein PO represents a polyolefin polymer produced by the polymerization of a monomer comprising an ethyleneor an olefin having 3 to 20 carbon atoms, wherein a group inside the parentheses represents a polar group; A and B independently represent any one selected from R1, a cyano group, C(O)OR1 and C(O)NR1R2, provided that A and B may together form a cyclic structure; M represents a metal cation or an onium cation; j represents the number of the metal cation(s) or the onium cation(s), and is an integerof 0 to 4; i represents the number of valency of the metal cation or the onium cation, and is an integer of 0 to 4; D and E independently represent any one selected from an oxygen atom, a nitrogen atom, a sulfur atom, R3, OR3, SR3 and NR3R4, provided that D and E may together form a cyclic structure; d and e represent the number of valency of the substituent D and the number of valency of the substituent E, respectively, and independently represent an integer of 0 to 4; R1, R2, R3 and R4 independently represent any one selected from a hydrogen, an optionally substituted alkyl, alkenyl, alkynyl, aralkyl or aryl group having 20 or less carbon atoms, and a group having a heterocyclic ring; and n represents the average number of the functional groups, and is a number of 0.80 to 10.0.
Owner:MITSUI CHEM INC

Polyolefin polymer having polar group, method for production thereof, and water dispersion material and mold release agent composition

To provide a polyolefin polymer having a polar group represented by Formula (i) produced by modifying, with a high modification ratio, a double bond in a polymer having the double bond at one terminal, both terminals, or at the inside of a polymer chain thereof that is obtained by a known method; a method for producing the polyolefin polymer; and a water dispersion material and a mold release agent composition each containing the polyolefin polymer,wherein in Formula (i), PO represents a polyolefin polymer obtained by polymerizing a monomer including ethylene or including an olefin having 3 to 20 carbon atoms, and a group shown in the brackets is the polar group of the polyolefin polymer; A and B each independently represent R1, a cyano group, C(O)OR1, or C(O)NR1R2, and A and B may be combined to form a cyclic structure; M represents a metal cation or an onium cation; j is an integer of 0 to 4 representing the number of the metal cation or the onium cation; i is an integer of 0 to 4 representing the number of valency of the metal cation or the onium cation; D and E each independently represent an oxygen atom, a nitrogen atom, a sulfur atom, R3, OR3, SR3, or NR3R4, and D and E may be combined to form a cyclic structure; d and e each independently are an integer of 0 to 4 representing respectively the number of valency of the substituent D and the number of valency of the substituent E; R1, R2, R3, and R4 each independently represent hydrogen, an optionally substituted alkyl, alkenyl, alkynyl, aralkyl or aryl group having 20 or less carbon atoms, or a group having a heterocyclic ring; and n represents the average number of functional groups, and ranges from 0.80 to 10.0.
Owner:MITSUI CHEM INC

Surface modification method of nano silicon dioxide

The invention discloses a surface modification method of nano silicon dioxide, which comprises the steps of adding nano silicon dioxide into a mixed solution of ethanol and water, carrying out ultrasonic treatment at room temperature for 15-25 minutes, regulating the pH value to 4-6 by using hydrochloric acid to obtain an acidic dispersion liquid, heating the acidic dispersion liquid to 90-100 DEG C, adding a fluorine-containing silane coupling agent, carrying out heat-preservation reaction for 20-30 hours, and drying the reaction liquid in a drying oven at the temperature of 70-90 DEG C to obtain the modified nano silicon dioxide. Nano silicon dioxide particles are modified by the tridecafluorooctyltriethoxysilane coupling agent, and hydroxyl groups on the surface of the nano silicon dioxide are replaced by the coupling agent, so that the dispersity, compatibility and stability of the nano silicon dioxide in an organic dispersing agent or a matrix are improved.
Owner:ELECTRIC POWER RESEARCH INSTITUTE OF STATE GRID SHANDONG ELECTRIC POWER COMPANY +1

Photonic crystal sensing material for SEB ultra-sensitive detection, preparation method thereof and method for ultra-sensitive detection of SEB

The invention belongs to the field of toxin detection, and relates to a photonic crystal sensing material for SEB ultra-sensitive detection, a preparation method of the photonic crystal sensing material and a method for ultra-sensitive detection of SEB. The preparation method comprises the following steps: carrying out hydrolysis reaction on tetraethyl orthosilicate to obtain silicon spheres; mixing and reacting the silicon spheres with 3-aminopropyl triethoxysilane to obtain aminated silicon spheres; carrying out contact reaction on an aqueous solution of aminated silicon spheres and a nanogold solution to obtain aminated silicon spheres SiO2-AuNPs modified with nanogold particles, preparing a SiO2-AuNPs microsphere suspension, performing drying in a constant-temperature drying oven, andperforming stacking to obtain photonic crystals; and adding the SEB aptamer of which the 5'end is modified with sulfydryl into the SiO2-AuNPs photonic crystal, and performing incubating to obtain theSEB aptamer-photonic crystal sensing material. The photonic crystal sensing material provided by the invention can realize ultrasensitive and label-free detection of SEB.
Owner:INST OF ENVIRONMENTAL MEDICINE & OCCUPATIONAL MEDICINE ACAD OF MILITARY MEDICINE ACAD OF MILITARY SCI

Polymerization initiator, modified conjugated diene-based polymer, and methods for preparing them

The present invention relates to a polymerization initiator represented by Formula 1, a modified conjugated diene-based polymer, methods for preparing them, a rubber composition comprising the modified conjugated diene-based polymer, and a tire prepared from the rubber composition.(In Formula 1, the definition of each substituent is the same as defined in the description.)
Owner:LG CHEM LTD

6-O-N-trimethyl chitosan chloride-SOD (superoxide dismutase) modifier and preparation thereof

InactiveCN104357433ARetain activityImprove activity retentionEnzyme stabilisationOxidoreductasesN-trimethyl chitosan chlorideHalf-life
The invention relates to a 6-O-N-trimethyl chitosan chloride-SOD modifier and a preparation thereof. The modifier is formed by combining a carboxyl on an SOD molecule with an amino group on an O-HTCC molecule through an amido bond; one O-HTCC molecule and one to ten SOD molecules are combined. The invention further relates to a preparation method of the 6-O-N-trimethyl chitosan chloride-SOD modifier. Compared with natural SOD, the O-HTCC-SOD modifier remains the activity of decomposing superoxide anions by SOD, integrates the favorable characteristics of O-HTCC, and has the characteristics of high stability, long half-life period and low immunogenicity; compared with TMC, the efficiency of modifying SOD by O-HTCC is high, and therefore, the 6-O-N-trimethyl chitosan chloride-SOD modifier has a better using effect and a wider application range.
Owner:SHANDONG UNIV

Preparation method for nanometer modified magnesium hydroxide

The invention provides a preparation method for nanometer modified magnesium hydroxide. The objective of the invention is to provide the ultrafine magnesium hydroxide preparation method with the advantages of high yield, short process flow, no pollution during production, narrow particle size distribution and capacity of realizing ultra-refining and surface modification in one step. According to a technical scheme in the invention, the preparation method comprises the following steps: mixing, stirring and beating magnesium hydroxide powder with a particle size of 325 to 8000 meshes, a surface modifier and a solvent in a (weight) ratio of 1000: 1-80: 1000-5000; then allowing the obtained slurry to pass through grinding equipment, filling a grinding cavity with spherical medium grinding beads with a diameter of no more than 0.8 mm and carrying out grinding in an environment where a filling volume ratio is greater than 35% and the minimum movement speed of the grinding beads is greater than 10 m / s; and allowing the slurry obtained after grinding to pass through drying equipment so as to obtain surface-modified ultrafine magnesium hydroxide powder with average particle size distribution in a range of 50 to 500 nm.
Owner:SUZHOU BAO SHUN MEI TECH CO LTD

Antibacterial and antiviral toilet lid and preparation method

The invention relates to an antibacterial and antiviral toilet lid and a preparation method thereof. The antibacterial and antiviral toilet lid is prepared from the following components in parts by weight: 60-70 parts of a resin material, 10-20 parts of a flame-retardant filler, 1.0-5.0 parts of a dispersing agent, 1.0-2.0 parts of an antioxidant and 0.5-1.0 part of a modified antibacterial and antiviral treatment agent, wherein the modified antibacterial and antiviral treatment agent adopts an organic silicon modified photocatalyst, and the organic silicon modified photocatalyst is obtained by modifying an inorganic photocatalyst antibacterial agent with an organic silicon release agent. In addition, the invention also discloses a preparation method of the antibacterial and antiviral toilet lid. On the premise of ensuring the antibacterial, antiviral and anti-mite effects of the toilet lid, the use amount of the antibacterial agent is greatly reduced.
Owner:同曦集团有限公司

Modified monomer, modified polymer including the same, and methods of preparing the same

The present invention relates to a substituted styrene-based compound represented by Formula 1 (refer to the specification and the scope of the claims), a method of preparing the styrene-based compound, a modified polymer including a functional group derived from the substituted styrene-based compound, a method of preparing the modified polymer, a rubber composition including the modified polymer, and a molded article manufactured from the rubber composition.
Owner:LG CHEM LTD

Deacidification agent based on sodium phytate-modified nano magnesium oxide and preparation method of deacidification agent

The invention relates to a deacidification agent based on sodium phytate-modified nano magnesium oxide and a preparation method of the deacidification agent. The preparation method comprises the following steps: firstly, respectively dispersing nano magnesium oxide and sodium phytate in deionized water and alcohol solvent; then, mixing the two solutions in proportion for modification; then, dispersing the modified nano magnesium oxide in the mixed solvent of perfluoroheptane and petroleum ether to obtain the target deacidification agent. The deacidification agent has advantages of easily available raw materials, mild reaction conditions, simplicity and convenience in preparation and use methods, low dosage, high efficiency and good and uniform deacidification effect.
Owner:HUBEI TAIDEANXIN INFORMATION TECH CO LTD

Modified polymer, method of preparing the same, and rubber composition including the modified polymer

The present invention relates to a modified polymer having a high modification ratio and an excellent affinity with a filler, a method of preparing the same, a rubber composition including the modified polymer, and a molded article prepared from the rubber composition. The modified polymer according to the present invention may exhibit a high modification ratio by including functional groups in a polymer main chain and on at least one end thereof, and thus, an affinity with a filler, such as silica, may be excellent. Also, the rubber composition according to the present invention may have excellent processability by including the modified polymer having an excellent affinity with the filler, and, as a result, a processed product (e.g., tire) prepared by using the rubber composition may have excellent tensile strength, abrasion resistance, and wet road surface resistance.
Owner:LG CHEM LTD
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