46results about How to "Improve biochemical indicators" patented technology

The invention provides a modular sludge thermal hydrolysis treatment method and device. The sludge thermal hydrolysis treatment device comprises a thermal hydrolysis reaction kettle, a cooling jackettank and a measuring bin, and the measuring bin, the thermal hydrolysis reaction kettle and the cooling jacket tank communicate sequentially. The modular sludge thermal hydrolysis treatment device andmethod have the beneficial effects that: 1, sludge is subjected to a thermal hydrolysis reaction, so that the biodegradability of the sludge is greatly improved, the dehydration property of the sludge is greatly improved, poisonous and harmful pathogenic bacteria and toxic substances in the sludge are killed, and the reduction, harmlessness and recycle of the sludge are realized; 2, no alkaline agents are added in the process, so that the temperature and pressure of sludge thermal hydrolysis treatment are greatly reduced, the equipment grade, energy consumption and cost are reduced, and the treatment efficiency is increased; 3, the biochemical indexes of thermal hydrolysis slurry of a sludge thermal hydrolysis treatment process are increased, and the B / C ratio of the biochemical indexes is increased from 0.24 to 0.5; and 4, due to the adoption of the sludge thermal hydrolysis treatment process, the concentration of odor in the reaction kettle is greatly reduced from the source.

The invention discloses a compound traditional Chinese medicine composition and application thereof to resistance to prostate cancer. The compound traditional Chinese medicine composition is mainly prepared from the following traditional Chinese medicine raw materials in parts by weight: 4-12 parts of bark of ailanthus altissima, 12-30 parts of spreading hedyotis herb, 3-15 arts of curcuma zedoary, 15-30 parts of salvia miltiorrhiza, 5-15 parts of selfheal and 4-12 parts of liquorice. According to the compound traditional Chinese medicine composition having a prostate cancer-resistant effect, a raw material composition formula is selected according to the traditional Chinese medicine theory and pathogenesis of prostate cancer, all components are scientific and reasonable in ratio, and pharmacological experiment and preclinical experiment results show that the compound traditional Chinese medicine composition provided by the invention has a good prostate cancer-resistant effect, not only can obviously restrain the proliferation and growth of the prostate cancer, but also can restrain migration, invasion and transfer of the prostate cancer, obviously improve the survival quality of tumor-bearing mice, and improve all immune indexes of the tumor-bearing mice, is convenient and rapid in administration route, has no obvious adverse effects, can be developed to be a new-generation prostate cancer-resistant drug and has high potential of becoming a good prostate cancer treatment prescription.

The present invention discloses an application of corydalis saxicola and a preparation thereof in treating non-alcoholic fatty liver diseases and / or non-alcoholic steatohepatitis. According to the invention, through a large amount of experimental screening, it is found that corydalis saxicola total alkaloids have good effects of reducing synthesis in fatty acid cells, and can reduce the levels ofTG, TC, LDL cholesterol, HDL cholesterol and free fatty acid induced by HFD. Animal anatomical experiments show that the corydalis saxicola total alkaloids can effectively reduce the weight of livers,and pathological sections show that liver tissues are well protected. In addition clinical experiments show that corydalis saxicola total alkaloid capsules can obviously improve biochemical indexes and imaging evaluation results of fatty liver patients. The drug-induced liver injury experimental results show that the corydalis saxicola total alkali capsules can obviously improve drug-induced liver injury and have the effect of preventing liver injury.

The invention relates to a chicken feed, and especially relates to a feed for increasing the egg laying rate of under-forest free-range chickens. The feed is prepared from the following raw materials in parts by weight: 5-7 parts of wheat bran, 15-20 parts of soybean meal, 3-6 parts of peanut meal, 60-64 part of corn, 1-1.5 parts of bone meal, 0.1-0.2 part of a compound enzyme, 0.02-0.05 part of vitamins, 0.2-0.3 part of fluorine-free calcium hydrogen phosphate, 0.05-0.1 part of methionine, 0.2-0.4 part of table salt, 0.5-0.6 part of radix astragali, 0.6-0.7 part of codonopsis pilosula, 0.2-0.4 part of radix scutellariae, 0.5-0.7 part of honeysuckle, 0.3-0.5 part of agastache rugosus, and 0.5-0.8 part of hawthorn. The feed for increasing the egg laying rate of the under-forest free-range chickens can increase the food intake, egg laying amount and egg quality of laying hens, improves the blood biochemical index, enhances body immunity and reduces the death and culling rate, and eggs have no antibiotic residues.

The invention discloses a composition for dispelling effects of alcohol and protecting liver and a preparation method and application of the composition, and belongs to the technical field of medicines. The composition comprises effective components prepared from the following raw materials in parts by weight: 10 to 20 parts of deproteinized calf blood extractive, 10 to 20 parts of cordyceps militaris, 30 to 50 parts of mulberry, 20 to 40 parts of barbary wolfberry fruit, and 10 to 30 parts of radix puerariae. The preparation method of the composition comprises the steps of extracting calf blood by the expression method to obtain the deproteinized calf blood extractive; uniformly mixing cordyceps militaris, mulberry, barbary wolfberry fruit and a radix puerariae extractive to obtain the composition. According to the composition, all raw materials act together to realize the effects of dispelling effects of alcohol and protecting liver.

A hericium erinaceus mycelium polysaccharide with the effect of preventing and treating senile dementia and a preparation method are disclosed. Hericium erinaceus mycelium obtained through a liquid submerged fermentation technology serves as a raw material, the neuroprotective effect serves as an evaluation standard, and the novel purified hericium erinaceus mycelium polysaccharide is obtained through extraction, separation and purification, and is composed of six monosaccharides including fucose, galactose, xylose, glucose, mannose and glucuronic acid; and experiments prove that in APP / PS1 mice, the hericium erinaceus mycelium purified polysaccharide obtained in the invention can obviously shorten platform searching time and movement distance of the mice, improve platform jumping staying time of the mice, and reduce platform jumping-off times, and has effects of improving the cognition and memory ability of APP / PS1 mice, effectively reducing the levels of Abeta1-42, Tau (phospo S396) and 4-HNE in hippocampal regions of the mice, relieving AD pathological symptoms and improving the cholinergic system and the antioxidant ability.

The invention discloses application of a THBS1 cytokine in preparation of a medicament for treating hepatic failure. The temperature for transport and storage of the THBS1 cytokine-containing medicament is 2-8 DEG C, the humidity is 45-75%, and the THBS1 is a member of an ABCA superfamily and is mainly used for mediating transmembrane transport of lipids. In the application of the THBS1 cytokine in preparation of the medicament for treating hepatic failure, the biochemical indexes of patients can be significantly improved, the bilirubin level is lowered, the transaminase is reduced, the bloodcoagulation function is improved, the albumin level is raised, hepatocyte death is inhibited, regeneration of hepatocytes and bile duct cells is promoted, fatal complications such as major upper gastrointestinal duct bleeding, severe hepatic encephalopathy and hepatorenal syndromes are prevented, the survival time is significantly prolonged, and the survival rate is increased.

The invention discloses an Anhui local pig breeding method capable of improving the meat quality based on Chinese pennisetum silage. The breeding method specifically comprises the steps of feeding a local variety pig of the weight of 50 kg or above three times every day, wherein the feeding time is 6:00-7:00 in the morning, 11:00 at noon and 17:00-18:00 in the evening, the pig is fed with concentrated feed and pick and eat food freely in the morning and in the evening, it is ensured that the feed for the pig is continuous, the pig finishes the feed within 1.5 h and there is no surplus, and thepig is fed with the Chinese pennisetum silage of 0.5-1.0 kg at noon. According to the Anhui local pig breeding method capable of improving the meat quality based on the Chinese pennisetum silage, thegrowth and slaughter performances of the local variety pig are improved, the pig meat quality is improved, the pig meat nutrient content is improved, the pig protein metabolized serum biochemical criterion is improved, and the breeding benefit of the live pig is increased. Feed formula ingredients involved in the method are all food crops and processing by-product, a nutritive additive is added,there is no residual medicine, and the formula is scientific and obvious in effect and has popularization value.

The invention provides a hypertension liver-yang hyperactivity rat model discrimination method. According to the discrimination method, discrimination indexes are comprehensive, and special material groups generated in the hypertension liver-yang hyperactivity occurrence and development process are included. The method comprises the steps that a hypertension liver-yang hyperactivity rat model is copied as a disease group, macroscopic and biochemical physical indexes are measured, data is selected and brought into the hypertension liver-yang hyperactivity rat PLS regression model, if the disease group and the model group in a PLS two-dimensional score plot are separated, the built hypertension liver-yang hyperactivity rat model is successful, and if not, the built hypertension liver-yang hyperactivity rat model is not successful.

The present invention relates to applications of a natural plant molecule 3'-geranylchalconaringenin and a composition in preparation of products for treating fatty liver. The 3'-geranylchalconaringenin has a simple extraction and separation or synthesis method, is relatively low in cost, and has small toxic and side effects due to food-derived substances, so that the applications of the 3'-geranylchalconaringenin and composition in the preparation of functional foods, health-care products and medicines for treating fatty liver have huge market potential.

The invention provides a medicine for treating the vascular endothelial injury, the stenosis and the occlusion of the heart, the brain and the kidney mainly, which relates to a medicine of traditional Chinese medicines for treating diseases in the aspect of blood vessels. The medicine for treating the vascular endothelial injury, the stenosis and the occlusion of the heart, the brain and the kidney mainly is prepared by the following raw materials: 1 to 3 parts of radix salviae miltiorrhizae, 0.5 to 2 parts of radix notoginseng, 0.5 to 2 parts of leech, 0.5 to 2 parts of land tortoise plastron, 0.5 to 2 parts of crude turtle shell, 0.5 to 2 parts of scorpio, 0.5 to 2 parts of rhizoma alismatis, 0.5 to 2 parts of sea cucumber, 0.4 to 1.2 parts of ginseng and 0.1 to 0.4 parts of bear gall powder; when the medicine for treating the vascular endothelial injury, the stenosis and the occlusion of the heart, the brain and the kidney mainly is prepared, liquor is obtained after the operations of conventional alcohol extraction and water extraction are carried out on the raw materials except for the radix notoginseng, the sea cucumber and the bear gall; and the liquor is concentrated to clear paste of which the relative density is 1.32 to 1.40 (50 DEG C), then the clear paste is stirred with the pulverized matters of the radix notoginseng, the sea cucumber and the bear gall, and the mixture is dried so as to prepare particulate matters containing 17.4 percent of total sugar, 13.8 percent of protein, 180mg / 100g of total flavone and 559mg / 100g of total saponin. The medicine for treating the vascular endothelial injury, the stenosis and the occlusion of the heart, the brain and the kidney mainly has the following beneficial effects that the medicine for treating the vascular endothelial injury, the stenosis and the occlusion of the heart, the brain and the kidney mainly has a high curative effect, and no toxic or side effect, and is low in cost, and the phenomenon of relapse does not occur after healing; and by 69 cases of clinical trial, the effective rate is 99 percent, and the cure rate is 65 percent.

The invention provides a feed enzyme preparation capable of reducing diarrhea of weaned piglets. The feed enzyme preparation includes a complex enzyme, tea polyphenol and a carrier; the complex enzymeincludes 2,000 U / g of glucose oxidase, 3,000 U / g of amylase, 8,000 U / g of acid protease, 2,000 U / g of acid mannanase and 10,000 U / g of xylanase; and the carrier includes one or more of corn starch, mountain flour, medical stone or rice bran. A preparation method of the feed enzyme preparation includes the following steps: weighing each component of the complex enzyme preparation in proportion; uniformly mixing each component of the complex enzyme, and adding the tea polyphenol and the carrier into a double-shaft efficient mixer to mix, mixing time being 10-15 min; and performing mixing uniformity detection on a finished product after mixing, and ensuring that the coefficient of variation is less than or equal to 5%. The feed enzyme preparation can enhance the growing performance of weanedpiglets and reduce feed-meat ratio and diarrhea rate, and is an eco-friendly additive.

The invention discloses a wormwood traditional Chinese medicine micro-ecological fermentation preparation and a preparation method and application thereof, and relates to the field of livestock and poultry breeding. The wormwood traditional Chinese medicine micro-ecological fermentation preparation comprises lactobacillus rhamnosus YL198 bacterial suspension and wormwood, and the volume-to-weightratio of the lactobacillus rhamnosus YL198 bacterial suspension to the wormwood is 1L: 100kg-1L: 500 kg; the lactobacillus rhamnosus YL198 is preserved in China Center for Type Culture Collection on November 27, 2020, and the preservation number of the lactobacillus rhamnosus YL198 is CCTCC NO: M2020781. The lactobacillus rhamnosus YL198 is used for fermenting the traditional Chinese medicine wormwood; meanwhile, a magnetic field generated by terahertz ore is used in cooperation for assisting probiotic fermentation and fermentation conversion of wormwood bioactive components, the pH value of the obtained traditional Chinese medicine microecological preparation ranges from 3.0 to 3.5, and the product has the functions of enhancing body immunity, adjusting intestinal flora, improving the stomach and intestine and the like; the feed additive is green, environment-friendly, safe, effective and stable, and can be used for replacing or reducing antibiotics.

The invention provides application of peach gum polysaccharide to preparing a drug or a healthcare product used for treating or preventing nephritis and a pharmaceutical composition, and belongs to the technical field of traditional Chinese medicines. The inventor finds through the research that the peach gum polysaccharide effectively improves the biochemical criterion of nephritis, improves theimmunity, diminishes the inflammatory reaction, recovers the vigor of renal corpuscle, has a certain bacteriostatic action, and can be used to treat diseases of the urinary system like nephritis. Thepeach gum polysaccharide can be applied separately or together with other drugs to prepare the drug or the healthcare product for treating or preventing related diseases like renal corpuscle injuries,and can be used to alleviate the injuries of the renal corpuscle cells caused by other drugs, and provides a novel treatment means and thinking for the diseases caused by the injuries of the renal corpuscle cells.

The invention discloses an application of a Zhenlong refreshing pharmaceutical composition in preparation of a medicine for treating diabetic peripheral neuropathy. A Zhenlong refreshing preparation is traditionally used for treating acute cerebral infarction, carotid atherosclerosis plaque, apoplexy sequela, etc. Pharmacological experiments and clinical observations prove that the Zhenlong refreshing pharmaceutical composition disclosed by the invention comprises a Zhenlong refreshing capsule and a Zhenlong refreshing pharmaceutical composition prepared by an improved process, the Zhenlong refreshing pharmaceutical composition obviously perfects the symptoms of a nervous system of a DNP (diabetic peripheral neuropathy) patient and can significantly improve the nerve conduction velocity and perfect a variety of biochemical indexes, so that the Zhenlong refreshing pharmaceutical composition can be used for treating and preventing DPN.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating hand-foot-and-mouth disease. The traditional Chinese medicine composition comprises, by weight, raw gypsum 8-12 g, radix scutellariae 1-5 g, flos lonicerae 4-8 g, radix isatidis 4-8 g, fructus arctii 1-5 g, periostracum cicada 1-5 g, common ducksmeat herbs 1-5 g, radix lithospermi 1-5 g, radix paeoniae rubra 1-5 g, agastache rugosus 1-5 g, american ginseng 1-3 g, antelope horn powder 0.1-0.5 g and born licorice 1-3 g. The traditional Chinese medicine composition for treating the hand-foot-and-mouth disease can relieve the clinical symptoms, quickly achieve the effect, shorten the disease course, improve the biochemical index, prevent severe cases from developing to critical cases and improve the cure rate.

The invention discloses a Liuwei Anxiao pharmaceutical composition and application of a preparation thereof in preparation of a drug for treating alcoholic hepatitis. The Liuwei Anxiao pharmaceutical composition comprises six medicine ingredients, namely, Tibet inula root, rheum officinale, rhizoma kaempferiae, fumed gypsum, fructus chebulae and tronae. The clinical test shows that the Liuwei Anxiao pharmaceutical composition can protect alcoholic liver injury and can also obviously improve AST (Aspartate Transaminase), ALT (Alanine Aminotransferase), GGT (Gamma Glutamyl Transpeptidase), TBiL (Total Bilirubin) and other biochemical indexes.

A traditional Chinese medicine compound combination with the anti-prostate cancer effect and its application. The traditional Chinese medicine compound combination comprises the following traditional Chinese medicine raw materials by weight: 4 to 12 parts of bark of Ailanthus altissima, 12 to 30 parts of Hedyotis diffusa, 3 to 15 parts of Curcuma zedoaria, 15 to 30 parts of Salvia miltiorrhiza, 5 to 15 parts of Prunella vulgaris, and 4 to 12 parts of Glycyrrhiza uralensis. For the traditional Chinese medicine compound combination with the anti-prostate cancer effect, the materials are selected and combined according to the theory of traditional Chinese medicine and the pathogenesis of prostate cancer, and the proportions of the components are scientific and reasonable. Results of pharmacology experiments and clinical experiments show that the traditional Chinese medicine compound has a good anti-prostate cancer effect, and not only can significantly inhibit the proliferation and growth of prostate cancer, but also can inhibit the migration, invasion, and metastasis of prostate cancer, significantly improves the quality of life of a tumor-burdened mice, and improves immune indexes of the tumor-burdened mice. In addition, administration of the compound is convenient and simple, and the compound brings no obvious adverse reaction. The traditional Chinese medicine compound can be developed as a new-generation anti-prostate cancer drug, and is expected to become an effective prescription for the treatment of prostate cancer.

The invention discloses the application of Liuwei Anxiao pharmaceutical composition and its preparation in the preparation of drugs for treating alcoholic hepatitis. It is composed of six herbs such as seed and alkali flower. Clinical trials have shown that the Liuweian Xiaosan pharmaceutical composition has a protective effect on alcoholic liver injury, and can significantly improve biochemical indicators such as AST, ALT, GGT, and TBiL. <pb pnum="1" / >

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating hand-foot-and-mouth disease. The traditional Chinese medicine composition comprises, by weight, raw gypsum 8-12 g, radix scutellariae 1-5 g, flos lonicerae 4-8 g, radix isatidis 4-8 g, fructus arctii 1-5 g, periostracum cicada 1-5 g, common ducksmeat herbs 1-5 g, radix lithospermi 1-5 g, radix paeoniae rubra 1-5 g, agastache rugosus 1-5 g, american ginseng 1-3 g, antelope horn powder 0.1-0.5 g and born licorice 1-3 g. The traditional Chinese medicine composition for treating the hand-foot-and-mouth disease can relieve the clinical symptoms, quickly achieve the effect, shorten the disease course, improve the biochemical index, prevent severe cases from developing to critical cases and improve the cure rate.

The invention belongs to the field of functional nutritional food, and in particular relates to a nutritional composition for treating liver cirrhosis and a preparation method thereof. According to the nutritional metabolism characteristics and required nutrients of Chinese liver cirrhosis population, the present invention scientifically formulates a nutritional composition for the treatment of liver cirrhosis, and through reasonable nutritional intervention, improves the nutritional metabolism state of patients with liver disease, promotes liver cell regeneration, and promotes liver regeneration. The recovery of function can effectively improve the biochemical indicators and Child-Pugh score of patients with liver cirrhosis, and improve the quality of life.

The invention provides application of a composition in preparation of a drug for inhibiting gefitinib hepatotoxicity. The composition consists of a PLK1 inhibitor BI-2536 and the gefitinib, wherein adose ratio of the gefitinib to the BI-2536 is 40:1. In vitro and in vivo studies have shown that PLK1 inhibitor BI-2536 has a significant protective effect on liver toxicity induced by the gefitinib.The PLK1 inhibitor can be used for preventing and reducing gefitinib-induced hepatotoxicity, thereby expanding the clinical application of the gefitinib. The significance of the composition is to provide an effective gefitinib liver toxicity-resisting protective agent against gefitinib-induced hepatotoxicity. A in vivo experimental study proves that the composition has a significant protective effect against liver toxicity caused by the gefitinib, thus expanding the clinical application range of the gefitinib, reducing the liver toxicity caused by the gefitinib in a cancer patient, and providing a brand-new liver toxicity protection mechanism.

The invention relates to a low-temperature-resistant rice seedling raising substrate and a preparation method thereof. The low-temperature-resistant rice seedling raising substrate comprises the following components in parts by weight: 50-60 parts of crop straw, 20-30 parts of livestock manure, 20-30 parts of juice production residues, 0.1-0.2 part of a fermentation inoculant, 10-15 parts of a filler, 0.5-1.0 part of a water-retaining agent and 0.1-0.2 part of a cold-resistant conditioning agent. The cold-resistant conditioning agent and other components with a heat preservation function are added into the rice seedling raising substrate, so that the germination rate of rice under the cold condition is remarkably increased, and the inhibition effect of cold stress on rice growth is relieved.

The invention provides a use of peach gum polysaccharide in the preparation of medicines for treating or preventing nephritis and a pharmaceutical composition, belonging to the technical field of traditional Chinese medicines. The inventor found that peach gum polysaccharide can effectively improve the biochemical indicators of nephritis, improve immunity, reduce inflammation, restore the vitality of renal corpuscle, and has a certain antibacterial effect, which can be used for the treatment of nephritis and other urinary system diseases. It can be used alone or in combination with other drugs to prepare drugs for the prevention or treatment of diseases related to renal corpuscle injury, and to relieve the damage caused by other drugs to renal corpuscle cells, which is a disease caused by renal corpuscle cell damage. Provide new treatment methods and ideas.

An orally taken Chinese medicine containing astragalose and chuanxiongzine for treating cerebral thrombosis, cerebral hemorrhage and their sequelae is prepared from astragalus root and Chuan-xiong rhizome through respectively extracting. Their extracting processes are also disclosed.

The invention discloses a composition for prevention and treatment on viral infectious myocarditis. Active ingredients of the composition comprise Trefolane A and Tubeimoside A in a weight proportion of 1: 1 to 20: 1. Trefolane A and Tubeimoside A have good effects of improving general conditions, a survival rate, serum malondialdehyde (M DA) and serum nitric oxide (NO) of Coxsackie virus-infected myocarditis and have significant effects of prevention and treatment on Coxsackie virus-infected myocarditis.

The invention discloses a device and a method for adsorbing and pretreating coal gasification wastewater by residual sludge and application. The device comprises a shell, wherein an adsorption sedimentation area and a sludge concentration area which are arranged up and down are defined in the shell; the adsorption reactor is arranged in the shell, a muddy water outlet is formed in the upper part of the adsorption reactor, a water and mud inlet is formed in the lower part of the adsorption reactor, and the adsorption reactor divides the adsorption settlement area into an adsorption area and a settlement area; the shell is communicated with the water outlet weir through a water outlet; the partition plate is arranged in the adsorption settling area, abuts against the top wall of the shell, the side wall of the shell and the outer wall of the adsorption reactor and divides the settling area into a first settling area and a second settling area, and only the bottoms of the first settling area and the second settling area are communicated. The device not only can realize the recycling of the waste residual sludge and reduce the treatment cost of the wastewater, but also can greatly reduce the concentration of organic matters in the wastewater and improve the biodegradability of the wastewater, and in addition, the device also has the advantages of simple structure, high treatment efficiency and easiness in operation.

The invention provides a pure traditional Chinese medicine preparation capable of quickly treating the hand-foot-and-mouth disease. The preparation is prepared from ixeris chinensis, herba Lycopodii, storax, vervain, gerbera, dayflower, gray vernonia, rabdosia amethystoides, cornu gorais, dandelion, cortex dictamni, ageratum conyzoides, gallnut, gypsum rubrum and red halloysite. The pure traditional Chinese medicine preparation capable of quickly treating the hand-foot-and-mouth disease has the effects of dispelling wind and clearing away toxin, removing toxin and eliminating dampness, supplementing qi and nourishing yin and the like, can promote regression of rash and oral herpes, shortens the disease course, has an obvious relieving and treating effect on clinical uncomfortable symptoms, can effectively improve biochemical indexes, and can fundamentally relieve pain of patients and family members of the patients.

The invention discloses application of a CTSG (cathepsin G) cell factor in the preparation of medicaments to treat hepatic failure. Death of mass hepatic cells occurs during the course of hepatic failure; the CTSG cell factor helps overcome the aforementioned problem. CTSG JNK (c-Jun N-terminal kinase) is one of MAPK (mitogen-activated protein kinase) family members; JNK pathway can inhibit apoptosis of hepatic cells by regulating the expression of CTSG. The CTSG cell factor can be applied to the preparation of medicaments to treat hepatic failure to significantly increase biochemical indexesof a patient, reduce bilirubin level, lower aminotransferase, improve the coagulation function, inhibit cell apoptosis, promote the regeneration of hepatic cells and bile duct cells, prevent occurrence of fatal complications, such as massive alimentary tract bleeding, severe hepatic encephalopathy and hepatorenal syndrome, extend the survival time of the patient significantly, and increase the survival rate.

The present invention provides a use of the DLL4 cell factor in preparing a drug for treating fulminant hepatic failure. DLL4 can not only significantly improve the survival rate in a treatment of fulminant hepatic failure, but also significantly improve the survival rate by improving prognosis of a treatment of a severe or terminal stage hepatic disease having a similar underlying cause, disease progression and prognosis.