The invention discloses pearl skin-care tweed and a production technology thereof. The skin-care tweed is prepared from 60% of mercerized wool fibers, 16% of polyester fibers, 20% of pearl fibers and 4% of lycra. The production technology of the pearl skin-care tweed comprises the dyeing procedure, the spinning procedure, the weaving procedure and a post-finishing procedure. The pearl fibers have the beauty maintaining and skin caring effects of pearls, and also have the moisture absorption, air permeability and comfortable wearability characteristics of cellulose fibers; the pearl fibers, mercerized wool and the polyester fibers are blended, and the lycra is added, so that the functions, such as beauty maintaining, skin caring, moisture absorbing, air permeability and ultraviolet prevention, of conventional wood fabrics are improved; the fabric has the advantages of being glossy, gorgeous, smooth in hand feeling, friendly to the skin, comfortable and the like, is suitable for wearing as a close-fitting fabric, meets requirements of consumers, and has a wide market space.