The invention relates to the technical field of textiles, in particular to a production method of special powder puff flannelette. Polyester filament yarns serve as raw materials and are woven by a double-rapier loom in a W-shaped consolidation manner, and a fabric is finished to obtain the special powder puff flannelette. The special powder puff flannelette has the advantages of bacteria resistance, high fluff elasticity reset capacity, good abrasion resistance, low cost and like, fluff cannot fall, and the stability of the fluff is better. According to the method, by the aid of the double-rapier loom, polyester filament yarns with denier count of 1-3 serve as raw materials to be woven and finished to obtain the flannelette, the fluff of the surfaces of the flannelette are full and vertical, the surfaces of the flannelette have natural comfort after the flannelette is finished by the method, and loose powder can be uniformly dispersed on the face of a user. A structure of a flannelette cutting knife is designed, the flannelette cutting efficiency of the production method of the special powder puff flannelette is improved, damage of the flannelette cutting knife to knitting wool can be prevented, flannelette cutting effect is better, and the method is particularly applicable to weaving of flannelettes taking the polyester filament yarns as the raw materials.