70 results about "Types diseases" patented technology

The invention provides a method and a device for identifying deformation type diseases of a pavement. The method comprises the steps of S1, according to pre-acquired three-dimensional model of the to-be-tested pavement, acquiring deformation depth information of the to-be-tested pavement; S2, according to the deformation depth information, extracting a suspected disease edge through an edge detecting algorithm; S3, acquiring a preliminary positioning disaster area according to the deformation depth information and the suspected disease edge, and positioning the disease area through area growthrestoring processing; and S4, acquiring the disease attribute set of the disease area, and identifying the disease type of the disease area according to the disease attribute set. According to the method and the device, through acquiring the disease depth information and a deformation depth image, the disease area in the pavement is accurately extracted, thereby ensuring integrity of the diseasearea. Furthermore the disease type of the disease area is accurately identified through the disease attribute, thereby realizing high-efficiency and high-accuracy testing and identification for the deformation type disease of the pavement.

The invention relates to a bactericidal composition comprising the effective components of fluazinam and mesopoion rhzomorph. The two effective components can carry out synergistic acting so as to reduce the application quantity and lower the resistibility risk. The invention is suitable for preventing and treating various diseases on melons, fruits and vegetables and is especially suitable for preventing and treating compound type diseases caused by fungi and bacteria on the melons, the fruits and the vegetables.

Antigen binding proteins that bind β-amyloid peptide, in particular human β-amyloid peptide; methods of treating diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated β-amyloid levels or β-amyloid deposits, including age related macular degeneration and glaucoma type diseases and β-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture.

The invention discloses heat-clearing and detoxicating tea which is characterized by comprising components of Chinese lobelia, loafing grass, herba hedyotis diffusae, Basil and honeysuckle flower. The heat-clearing and detoxicating tea has outstanding efficacy and low price, and one dose is only about RMB one yuan. The heat-clearing and detoxicating tea can be used for treating various heat type diseases such as common cold fever, sphagitis, various pyogenic infections with abscess, eczema and the like. The heat-clearing and detoxicating tea can be applied as a prescription and also can be prepared into health-care drinks, and the like.

Antigen binding proteins that bind β-amyloid peptide, in particular human β-amyloid peptide; methods of treating diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated β-amyloid levels or β-amyloid deposits, including age related macular degeneration and glaucoma type diseases and β-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture.

The invention discloses a central clinical case database system based on cloud services. The central clinical case database system based on the cloud services comprises a clinical case data storage unit, a diagnostic unit, an information integration analysis unit and a diagnostic scheme evaluation unit. The clinical case data storage unit is connected with the data input end of the information integration analysis unit through the diagnostic unit. The data output end of the information integration analysis unit is connected with the diagnostic scheme evaluation unit. The clinical case data storage unit, the diagnostic unit, the information integration analysis unit and the diagnostic scheme evaluation unit are integrated on a cloud service control terminal. The central clinical case database system based on the cloud services can store and analyze a clinical case base relevant to same-type diseases, drug use analyses, diagnostic methods and follow-up recovery conditions of clinical cases, and the optimal diagnostic scheme with relevant medical information for treating the kind of diseases, and has good application prospects.

The invention relates to tobacco ferredoxin capable of improving disease resistance of rice and a coding gene of the tobacco ferredoxin, and belongs to the field of disease-resistant genetic engineering of the rice. Tobacco ferredoxin Ferredoxin (NbFd) in effector protein XopL mediated plant cells generates ubiquitination, then the tobacco ferredoxin is degraded by proteasomes, and the number of plant cell chloroplasts entering the NbFd is reduced, so that transmission of electrons in photosynthesis is restrained, accumulation of active oxygen is caused, and plants are induced to produce an allergic reaction (HR) type disease-resistant reaction. Ferredoxin protein in the rice does not interact with XopL, but after Ferredoxin protein coding genes from tobacco are transferred into the rice,the resistance of the rice to bacterial leaf spot can be improved. The tobacco Ferredoxin protein coding gene NbFd obtained in the way of protein interaction can be used as a breeding gene resource ofthe rice for resisting bacterial leaf spots, and the resistance of obtained NbFd transgenic rice to the bacterial leaf spots can be notably improved.

The method relates to a method for making plant disease specimens. The method is suitable for making disease specimens of fruits, hard in pericarp, such as citrus fruits including citrus, lemon and kumquat and melon fruits including pumpkin, white gourd and Hami melon. The method includes keeping color of the fruits hard in pericarp and with typical disease symptoms; scraping out flesh and pulp inside the fruits; using wood bits to replace the pulp to fill the fruits to completely support the fruits open; using glue to adhere soil on pericarp which is cut off; disposing the fruits in a drying oven at 45-55 DEG C until the fruits are dried. The fruit-type disease dried specimens made by the method maintain original color and luster of the fruits and are typical in symptom, free of obvious change in disease symptom and visual and convenient to observe. In addition, consumption of several volatile agents is reduced, so that environment pollution and physical damage are reduced; development of experimental teaching is further facilitated, and teaching effect is improved. Consequently, the method is suitable for popularization and application.

The invention relates to methods based on the quantification of a set of biomarkers, preferably in biological samples isolated from skeletal muscle, for performing the diagnosis, prognosis and / or monitoring of muscular degeneration, preferably muscular degeneration caused by motor neuron diseases, more preferably amyotrophic lateral sclerosis (ALS); and to a kit for the diagnosis, prognosis and monitoring of said type of diseases. The method in the invention for the prognosis and / or monitoring of muscular degeneration makes it possible to determine the rate of progression of said degeneration (fast or slow rate of progression in relation to the normal rate of progression).

The medicine for treating depression and other mental disturb diseases is prepared with chlorimipramine, sulpiride, sodium valproate, borneol and Chinese herbal medicine extractum prepared with nutagrass flatsedge rhizome, arisaema with bile, wild jujube seed and other Chinese medicinal materials. The medicine consists of chemically synthetic medicine and Chinese herbal medicine component, and has synergistic treating effect, less toxic side effect, and good patient's compliance.

The invention discloses a method for constructing a model animal, which is used in the research area of veterinary lemology, pathology and pharmacology and relates to non-pig pig breeding, respiratory syndromes and porcine circovirus 2 type diseases. The method is characterized in that in an economical common experimental animal, a typical pathologic change is generated in a mouse through a specific toxic material attacking method, the successful construction of a disease model is proved by adopting the methods for weight weighing, pathological section preparation, PCR detection and ELISA antibody detection, a further basis is provided for an in vivo experimental research correlative with the co-infection of two viruses, and a certain basis is established for a pharmacological experiment research. The disease model in the method is high in stability, simple and convenient in operation and practical in a wide range. Because a pig body experiment has a long period and a high cost, a feminine pig is difficult to screen, and more importantly, a disease cannot be copied in a pig body, the construction of a small animal infection model is very necessary for vaccine immune effect evaluations and virus pathogenic mechanism researches.

The invention provides a kit for detecting a mutation site associated with methylmalonic academia-combined homocysteine CbIC (cobalamin C) type disease and a mutation site associated with medication guidance, and further provides a probe set for detecting the mutation sites and sequence information of a primer set for amplifying the probe set, mutation situations of related gene loci of a patientcan be identified by use of the probe set or the primer, so that acurate screening and diagnosis of a methylmalonic academia-combined homocysteine CbIC (cobalamin C) type patient can be realized, andtargeted guidance for folic acid medication for treatment can be provided.

The invention provides a pueraria lobata extract which is applied to drugs for preventing and treating bone loss diseases. The extract has the function of well inhibiting osteoclast forming and can be used for preparing the drugs for treating bone loss type diseases such as osteoporosis. The extract is obtained through the following steps: performing reflux extraction on dried pueraria lobata through ethanol, recovering ethanol to obtain extractum, dissolving the extractum by using distilled water and then leaching by using an organic solvent, and recovering the solvent after the extract is dissolved by ethanol. The pueraria lobata extract provided by the invention has the function of well inhibiting osteoclast forming, is from natural medicines, has few side effects and is safe in use.

The invention disclose a compact type disease prevention and production increase machine for greenhouse crops, which comprises a shell (13), a gas head (6), a pesticide gasification cup (8), an ozone generator (10) and a control panel (11), wherein the ozone generator (10) is arranged in the inner cavity of the shell (13); and the control panel (11) is arranged at the bottom of the shell (13). The invention omits a fluid director; the ozone generator is arranged in the inner cavity of the production increase machine; the control panel is arranged at the bottom of the shell; the invention has the advantages of compact structure and convenient transportation; and the concentration of carbon dioxide, the concentration of pesticides and the concentration of ozone can be automatically controlled at the same time.

The invention discloses a health-care neck protection pillow with double air pressure regulation and its technology. About one-third of a person's life is spent in sleep, and the pillow that accompanies the most important part of the human body has an important impact on human health. Stiff neck and cervical spondylosis are related to the suitability of the pillow. Everyone People have different living habits, and the softness and hardness of pillows cannot be unified. Up to now, there is no pillow product that can meet the needs of all people in terms of softness, comfort and height while providing various health care and neck protection. . The invention provides a health-care neck pillow with double air pressure adjustment and its technology. According to the optimal pillow stress position when the human head is sleeping, a separate and combined trapezoidal double-layer airbag structure is adopted, and each layer of airbags is operated by a separate airbag manual air pump. The ball control can be adjusted separately to adapt to different pillow hardness and overall height. It has double adjustment functions in terms of softness, comfort and height, so as to be suitable for neck protection and health sleep of various groups of people.

The invention provides a traditional Chinese medicinal composition for treating Alzheimer-type diseases, wherein the traditional Chinese medicinal composition comprises the following traditional Chinese medicinal raw materials forming active ingredients according to the weight: 7.5g of radix polygoni multiflori preparata, 5g of cultivated land, 7.5g of epimedium herb, 5g of cynomorium songaricum and 5g of dogwood. After 107 light-moderate AD patients are treated for 24 weeks and 48 weeks, the comparison result of MMSE (mini-mental state examination) curative effects are as follows: for the effective rate with 48-week treatment, the western-medicine control group is 55.77% and the Chinese-medicine group is 70.91%. According to the above results, for treating the Alzheimer-type diseases, the traditional Chinese medicinal composition for is better than the donepezil. When being applied clinically, the traditional Chinese medicinal composition is directly taken by is mixed with water, and is simple in use. The traditional Chinese medicine particles are packaged by an aluminium-foil bag without easy moisture absorption, the size is small and the carrying is convenient. The invention provides a new treatment direction for treating the Alzheimer-type diseases and has larger clinic application value.

[Problem] Provision of a novel compound having read-through activity and a drug for the treatment of nonsense mutation-type disease containing this compound.[Solution] A compound represented by the following general formula (1):and a pharmaceutical composition containing this compound.

The invention belongs to the technical field of microorganism application, and particularly relates to an antibiological inoculant for preventing and controlling tobacco rhizome type diseases and a preparation method thereof. The antibiological inoculant for preventing and controlling tobacco rhizome type diseases is characterized by comprising the major ingredients consisting of fermentation liquid obtained through mixed fermentation of strains 16029 and strains 16098. The antibiological inoculant can achieve the strong inhibition effects on three kinds of major pathogenic bacteria of rhizomediseases of tobacco bacterial wilt, tobacco black shank and black root rot diseases, and can be used as the biocontrol bacterial agent for the tobacco rhizome type diseases. The bacteria agent has good application prospects on the prevention and control of tobacco rhizome type diseases.

The invention relates to a traditional Chinese medicine composition for treating skin diseases. The composition is prepared from oyster, turtle shell, stir-baked squama manitis, dragon blood, herba artemisiae scopariae, felwort, cape jasmine, scutellaria baicalensis, lalang grass rhizome, semen plantaginis, rhizoma alismatis, radix bupleuri, salviae miltiorrhizae, dried radix rehmanniae, rhizoma atractylodis macrocephalae, poria cocos, rheum officinale, raw hawthorn, pawpaw, radix rehmanniae preparata, rhizoma sparganii, curcuma zedoary, ligustrum lucidum ait, angelica sinensis, radix paeoniae rubra, radix paeoniae alba, ligusticum wallichii, peach kernels, safflower carthamus, pericarpium citri reticulatae viride, pseudo-ginseng, earthworm, pericarpium citri reticulatae, radix curcumae, fructus lycii, fructus aurantii, rhizoma cyperi, rice sprout, malt, codonopsis pilosula, astragalus membranaceus and licorice root. The composition can be used for treating heat entering construction-blood and toxic heat flourishing, has the effects of clearing heat, cooling blood and relieving dizziness and itching, and is mainly used for treating erythroderma desquamativum, skin-loss type diseases, psoriasis, argyraemia and psoriasis.

The invention relates to traditional Chinese medicine for treating scalds, bedsores and hemorrhoid. The traditional Chinese medicine is prepared from crystalline mirabilite, radix et rhizoma rhei, sanguisorba roots, Japanese ampelopsis roots, rosin,flos lonicerae, Chinese ilex leaves, herba patriniae, herba houttuyniae, herba scutellariae barbatae, herba taraxaci, spreading hedyotis herbs, manyleaf paris rhizomes, cacumen biotae, cape jasmine fruits, herba violae,radix angelicae dahuricae, radix scutellariae, rhizoma coptidis, cortex phellodendri, radix sophora flavescentis, cortex ailanthi, common bletilla pseudobulb, myrrh, frankincense, unguent prepared from acacia catechu (L. f.) wild, sanchi, rhizoma polygoni cuspidati, angelica sinensis, common jujube bark, alum, pearls, carapax plastrum testudinis, carapax trionycis, flowers of citrus bigarradia, ganoderma, largehead atractylodes rhizomes, flos carthami, squama manis, cowherb seeds, earthworms, hanging clubmoss, centipedes, scorpions, borneol, musk and sesame oil. Effective constituents of the medicine are pulverized and sieved and then prepared into paste, the traditional Chinese medicine is capable of clearing away heat, drying dampness, cooling blood for hemostasis, relieving swelling and pain, promoting blood circulation to remove meridian obstruction, removing slough and promoting tissue regeneration, remarkable in treatment effect when used for treating skin diabrosis type diseases such as scalds, bedsores and hemorrhoid and wide in application prospect.

the invention discloses a detecting agent and method of pig streptococcus 2-typed disease through multiple-fluorescent PCR, which is characterized by the following: adopting primer and probe corresponding to MRP and EF genes; assembling the agent through selecting the marked fluorescent group and reacting system; establishing multiple fluorescent PCR method.

The present invention relates to a stem cell bank which stores stem cells collected from individuals throughout their entire life. The stem cell bank of the present invention stores stem cells of various types, which are obtained from a plurality of sources from a single individual. The present invention further relates to methods of personalized medicine that utilizes cells stored in a bank of the present invention, and to compositions of stem cells for the treatment of various types of diseases.

The invention relates to conservation area design annex primer of CDS sequence of IL8 genes. Distilling total RNA from spleen perch, using PCR method to expand and combining RACE technology, the full expression sequence of interleukin 8 (IL-8) would be cloned to perch agglutinin. It lays a foundation for researching fish inflammatory reaction. It would gain pure albumen with bioactivity to supply new theory foundation for new type disease against.

The invention provides a split-type disease and insect pest pesticide liquid spraying device based on corn planting. The split-type disease and insect pest pesticide liquid spraying device comprises aleft bearing, a right bearing, a driving wheel and a pull frame; a left frame and a right frame are both L-shaped plate bending pieces, and the inner end faces of the left frame and the right frame are jointly connected with a function bin; the left bearing and the right bearing are symmetrically installed on the top faces of the left frame and the right frame left and right, and mobile wheels are further installed on the bottom faces of the left frame and the right frame through welded wheel frames; a welding plate is vertically welded to the left side of the top face of the left frame, a semi-circular arc opening is formed in the top of the welding plate, and a lateral leather bag is in screw fixation with the semi-circular arc opening. Other complicated mechanisms actuated by a fertilizer application mechanism are omitted, and a helpful structure with two kinds of functional linkage actuation is achieved. In this way, the split-type disease and insect pest pesticide liquid sprayingdevice is simple in structure and can complete fertilizer application and downward pesticide liquid spraying simultaneously after being hung on an agricultural vehicle, and therefore, agricultural bacteria which are turned out when soil is turned in the last working procedure are quickly killed in the next working procedure of fertilizer application.

The invention discloses a movable imaging type disease-pest recognition system and device. The system comprises an LED background collection device, a remote image collection device, a solar photovoltaic power supply device, a cloud server and a client recognition system, wherein the LED background collection device, the remote image collection device and the client recognition system are in bidirectional signal connection with the cloud server, and the LED background collection device and the remote image collection device are connected with the solar photovoltaic power supply device. A moth-killing lamp in the system is adjustable, so that the system is suitable for the planting scenes of multiple crops and convenient for user analysis and centralized management; and meanwhile, by utilizing software comparison recognition, the recognition speed is high, and the precision is high.

The invention provides environment-friendly energy-saving type diseased animal innocent treatment equipment which comprises an inedible rendering processor, a tail gas decontamination plant, a pressure reducer, a quench cooler, a buffer, a cooler, a waste residue recovery device and a grease recovery device. The inedible rendering processor comprises a cylindrical barrel, a movable feeding door, a movable slag outlet door and a heating hearth, the movable feeding door is arranged at the end of the cylindrical barrel, the movable slag outlet door is arranged at the middle portion of the movable feeding door, and the heating hearth us arranged below the cylindrical barrel. The inedible rendering processor is provided with a slag outlet, an outlet and a tail gas opening, the slag outlet is connected with the waste residue recovery device, and the tail gas opening is connected with the tail gas decontamination plant; and the outlet, the pressure reducer, the quench cooler, the buffer, the cooler and the grease recovery device are sequentially connected. The environment-friendly energy-saving type diseased animal innocent treatment equipment has the beneficial effects of being harmless and high in efficiency.

The invention relates to the field of health care products, particularly to a traditional Chinese medicine composition, a preparation method thereof and a prepared health care wine. The traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight: 5-15 parts of bilberry, 5-15 parts of sambucus chinensis, 5-15 parts of rhodiola rosea, 5-15 parts of glossy ganoderma, and 10-20 parts of grape seed. The traditional Chinese medicine composition provided by the invention is prepared from the raw materials in a specific ratio, the prepared traditional Chinese medicine composition is high in effective active components, and can well repair the metabolizing function of a human body, so that the human body can normally function well, the traditional Chinese medicine composition has good repairing function for the purine metabolic disturbance of the human body, and has remarkable treatment effects on gout and rheumatic type diseases caused by purine metabolic disturbance; in addition, the traditional Chinese medicine composition has the efficacy of improving the immunity of the human body. The traditional Chinese medicine composition performs water extraction on the raw materials in a heating and distillating manner, the effective active components are effectively merged at a high temperature, and the traditional Chinese medicine composition has a better effect.

The invention relates to an affinity agent of TIGIT-IgV and application thereof. The affinity agent of the TIGIT-IgV is selected from amino acids with sequence shown as SEQ ID NO. 1, 3 or 4, or structure shown as formula I or II, namely X1-Tyr-X2-His-X3-Arg-X4-X5 (I) or X1-Tyr-X2-His-X3-Arg-X4-X5-(L)n-X6 (II). The affinity agent of the TIGIT-IgV is found out by performing repeated screening and optimizing in a unique way, and is capable of relatively well blocking interaction between TIGIT and PVR, thereby treating tumors or other types of diseases.

The invention relates to an application of Metrnl protein or a Metrnl gene to the respect of preventing and treating cognitive disorder. According to the application disclosed by the invention, a Metrnl systemic knockout mouse and a corresponding wild type contrast mouse are adopted, a D-galactose induced dementia model is prepared, learning and memory functions are detected through a Morris watermaze experiment, the result displays that compared with the wild type contrast mouse, the learning and memory functions of the Metrnl knockout mouse are reduced, protein expression of brain-derived neurotrophic factors and the like in a hippocampus is reduced, and it is indicated that the Metrnl can be used for preventing and treating cognitive dysfunction type diseases. A new method is providedfor preventing and treating cognitive disorder; and the Metrnl is a human body endogenous substance and possibly has small side effects on human bodies, so that the safety of the Metrnl as a potentialmedicine is very high.