31 results about "Traumatic brain damage" patented technology

The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily fluids. Utilization of such methods improves diagnosis and treatment of patients suffering from traumatic brain injury, thus potentially minimizing and / or eliminating long-term adverse effects in these patients.

The invention belongs to an oral Chinese herbal preparation for treating post-traumatic brain syndrome, and the oral Chinese herbal preparation is a human medicinal product. The preparation is prepared from the following Chinese herbs in parts by weight: 10+ / -2 parts of Astragalus mongholicus, 10+ / -2 parts of American ginseng, 10+ / -2 parts of Angelica sinensis, 10+ / -2 parts of medlar, 10+ / -2 parts of the root of red-rooted salvia, 10+ / -2 parts of ligusticum wallichii, 10+ / -2 parts of root of common peony, 10+ / -2 parts of peach kernel, 10+ / -2 parts of Poria cocos, 10+ / -2 parts of pericarpium citri reticulatae, 10+ / -2 parts of plantain seed, 10+ / -2 parts of tabasheer, 10+ / -2 parts of rhizoma acori graminei, 10+ / -2 parts of gastrodia elata, 10+ / -2 parts of uncaria, 10+ / -2 parts of spina date seed, 10+ / -2 parts of amber powder and 6+ / -1.2 parts of honey-fried licorice root. Clinical effect observation proves that the total effective rate of the oral Chinese herbal preparation to the oral traditional Chinese medicine preparation is 94.07%, and has better treatment effect (P<0.01) compared with Western medicines such as Rotundine, piracetam, oryzanol and nimodipine for treating post-traumatic brain syndrome. Moreover, the Chinese herbal preparation has no obvious toxic or side effect, and can be taken for a long time. The dose of the preparation is small, and effective medicinal components are easy to release, can be absorbed quickly and can fully play the pharmaceutical effect. The preparation is convenient to carry, easy to take and beneficial to large-scale production.

A method of preventing, alleviating or treating traumatic brain injury in an individual comprises administering to the individual a therapeutically effective and physiologically acceptable amount of an agent capable of reducing the amount of one or more aggregated forms of one or more peptides in the brain. An agent capable of reducing the amount of one or more aggregated forms of one or more peptides in the brain is suitable for use in preventing, alleviating or treating traumatic brain injury. A method for predication of the risk of an individual for complications after a traumatic brain injury comprises detecting one or more aggregated forms of one or more peptides prone to aggregate as a result of a traumatic brain injury event, in the brain of the individual, wherein an increased level of such aggregates in the brain indicates an increased risk for complications.

Blast Induced Traumatic Brain Injury or bTBI needs objective and subjective testing that can be made quickly in the field. Subjective tests using shapes, textures, tastes and odors as disposable, edible candies on a stick may be carried in a field kit. An objective test that employs a similar candy on a stick bearing antibodies bound to bioluminescent marker reads whether molecules believed to be released into the mouth from an injured brain are present if they bind to the specific antibody which may then be read.