52 results about "PANAX JAPONICUS ROOT" patented technology

The invention provides a traditional Chinese medicine immunopotentiator for enhancing an immune function of broiler chickens during growth. The immunopotentiator comprises crude medicines such as aleppo avens, panax japonicus, platycodon grandiflorum, pokeberry roots, fructus psoraleae, hawthorn fruits, Chinese yams, honeysuckle, sargentgloryvine stems, fructus cnidii, artemisia apiacea, bighead atractylodes rhizome, cinnamon, sealwort, wolfberries, radix glehniae, angelica sinensis, isatis roots, mistletoe, polygonum multiflorum, herba fibraureae recisae, thlaspi arvense, gynostemma pentaphylla and liquorice. The traditional Chinese medicine immunopotentiator has functions of increasing weight and promoting growth of the broiler chickens, has a function of promoting the immune function, can enhance the organism immunity, can improve the anti-bacterial and anti-virus capability and can improve the meat quality. The traditional Chinese medicine immunopotentiator plays an important role in adjusting immune organs, immune cells and the specific immune function of the broiler chickens and can effectively reduce drug residues and pathogenic microorganism residues of animal products.

The invention relates to the field of plant cell culture and provides a method for acquiring secondary metabolites including panax japonicus saponins and the like with large-scale culture and a bioconversion technology for panax japonicus cells. The method comprises steps as follows: (1), auxins, cytokinins and a coagulator are added to an RW culture medium; (2), explant surface of panax japonicas is sterilized and callus is formed through induction; (3), the callus of the panax japonicas is subjected to subculture, and loose cell clusters are obtained; (4), a culture solution is prepared; (5), the loose cell clusters are transferred into the culture solution for culturing; (6), high-yield cell strains are cultured and screened; (7), the high-yield cell strains are subjected to multiplication culture; (8), a synthetic medium is prepared; (9), cells are continuously cultured in the synthetic medium, and bioconversion is completed; (10), purification is performed after extraction with a solvent. With the adoption of the method, the secondary metabolites of the panax japonicas can be produced, the production cost is low, the culture period is short, the method is not limited by natural environment, and annual production can be realized.

The invention discloses a Chinese herbal medicine extracting solution capable of preventing hair loss and holding hair. The Chinese herbal medicine extracting solution is prepared from the following ingredients in parts by weight: 30-50 parts of angelica sinensis, 45-70 parts of the root of three-nerved spicebush, 15-37 parts of crocus sativus, 15-50 parts of panax japonicus, 30-66 parts of garden nasturtium, 45-70 parts of polygonum multiflorum, and 50-90 parts of ligusticum wallichii. The Chinese herbal medicine extracting solution capable of preventing hair loss and holding hair can induce the hair, promote the hair growth, promote the hair follicle cell proliferation, prevent hair loss and hold the hair. The invention further discloses a preparation method of the Chinese herbal medicine extracting solution capable of preventing hair loss and holding hair, and the method is less in step, simple in procedure, safe in operation and low in cost. The invention further discloses a hair-growing cream and a preparation method thereof. The hair-growing cream is capable of effectively downward permeating from the healthy hair follicle of the hair to activate nearby necrotic hair follicle cells, thereby achieving the effect of growing new hair.

The invention discloses panax japonicus glycosyltransferase UGTPjm2 and an application thereof to preparation of panax japonicus sapinogenin IVa. The panax japonicus glycosyltransferase UGTPjm2 has anamino acid sequence as shown in SEQ ID No.1. The panax japonicus glycosyltransferase UGTPjm2 disclosed by the invention can catalyze glycosylation of C-28 site carboxyl groups of oleanolic acid-3-O-beta-glucuronide, and further, the panax japonicus sapinogenin IVa is generated. An important way is provided for artificial production of the panax japonicus sapinogenin IVa.

The invention discloses an anti-aging composition for cosmetics. The composition is prepared from, by weight, 10-20 parts of benzoinum, 6-15 parts of rutin, 8-15 parts of herba lycopi, 15-25 parts of rhizoma panacis japonici, 15-24 parts of Indian mockstrawberrg herb, 5-10 parts of roots of jasminum officinale and 8-15 parts of herba lycopodii. According to the anti-aging composition for the cosmetics, the synergistic enhancing effect among the raw materials is achieved, the anti-aging effect of the composition is increased, the drug efficacy is mild, the composition is formed by combining pure natural plant extracts, the side effect is small, the adaptability is wide, and the cost is low.

The invention relates to panax japonicus saponin used as a vaccine adjuvant as well as a preparation method and application thereof. The method comprises the following steps: extraction of the panax japonicus, extraction separation, resin adsorption and the like. The panax japonicus saponin is further separated and purified, the weaknesses of the traditional method that only the total saponins component is used and the main components of the samponin is not studied can be overcome, so that the problem that the drug ingredients are not known by people can be solved; an active part of the panax japonicus saponin has an obvious immunity adjuvant effect, and a way for developing the vaccine adjuvant is provided.

The invention relates to the technical field of medicines and in particular relates to a triterpenoid saponin compound chikusetsusaponin IVa separated from panax japonicus, derivatives and a preparation method thereof, a medicine composition containing the same and new medical application thereof to preparation of medicines for treating diabetes mellitus II. Biological activity tests show that the compound and the derivatives thereof have significant insulin sensitization activity, and can be used for preparing the medicines for treating diabetes mellitus II and complications which are caused by the diabetes mellitus II.

The invention discloses an application of panax japonicus saponin IV to preparation of an antilipemic agent. Based on a pharmacodynamic experiment, the panax japonicus saponin IV can remarkably reduce the contents of TG (triglyceride), TC (total cholestero) and LDL-C (low-density lipoprotein cholesterol) in blood serum of a mouse with low yolk hyperlipidemia disease, and increases the content of HDL-C (high-density lipoprotein cholesterol); and the safety is high, the antilipemic function is ensured, and a new choice is provided for clinic treatment of the hyperlipidemia disease.

The invention relates to application of panax japonicus IV a in prevention and treatment of cardiovascular disease and complication of the cardiovascular disease. Experiments show that the panax japonicus IV a has obvious protection effect on ischemia / reperfusion C57 mouse myocardium, the optimum dose is determined, and a medicine for preventing and treating the cardiovascular disease and related complication of the cardiovascular disease can be further prepared.

The invention discloses an application of panax japonicus polysaccharide, total saponins of panax japonicus, panax japonicus saponin V and a composition of panax japonicus polysaccharide and total saponins of panax japonicus in preparation of medicines for preventing and treating chronic obstructive pulmonary disease. The medicine containing the components is less in side effect, is originated from a single plant, is simple in component, and is definite in curative effect for preventing and treating COPD.

The invention provides an extraction method for a plant composition containing silybum marianum. The plant composition is prepared from 100 parts of silybum marianum, 50 parts of panax japonicus, 60 parts of pink reineckea herbs and 40 parts of zornia gibbosa through a microwave extraction method. The content is greatly increased, and the use amount is reduced. The invention further provides an application of the plant composition containing silybum marianum in preparing medicine for restraining mouse lymphoid tumor P388D1 cell proliferation.

The invention relates to a panax japonicas extract as well as a preparation method and application thereof. According to the invention, the method comprises the steps of preparation of panax japonicas raw material liquid, formation of a foam separation device and foam separation. By utilizing a high-fat diet molding technology, research is conducted in application and effect of the panax japonicas extract in an animal body, and the experimental result shows that the panax japonicas extract has favorable liver-protection and lipid-lowering activity, can obviously inhibit the formation of liver fibrosis, and has a good therapeutic effect on the liver fibrosis.

The invention discloses panax japonicus saponin glucoside hydrolase and application of the panax japonicus saponin glucoside hydrolase in production of gingerous notoginsenoside R1. The glucoside hydrolase is a protein with an amino acid sequence as shown in SEQ ID NO. 2. Experiments prove that the panax japonicus saponin glucoside hydrolase disclosed by the invention has the effect of efficiently converting ginsenoside Ro to generate notoginsenoside R1. Experiments prove that the panax japonicus saponin glucoside hydrolase also has the effects of efficiently converting panax japonicus saponin IVa to generate calendula officinalis glycoside E, efficiently converting panax japonicus saponin IV to produce aralia elata saponin VI, and efficiently converting pseudo ginsenoside RT1 to generate a corresponding C-28 deglucosylation product.

The invention relates to a method for preventing and controlling field rodent damage of bamboo ginseng, which is characterized in that it comprises the following steps: 1) preparing a rodent repellent; 2) placing the rodent repellent. A method for preventing and controlling rodent damage in the bamboo ginseng field of the present invention has the following advantages: firstly, it realizes the zero administration of rodenticide in the field of bamboo ginseng planting, which reduces the pollution to the farmland environment; secondly, the pests will not develop resistance The third is that it can be placed for a long time, which can realize the continuous control of rodent damage in the field of bamboo ginseng; the fourth is that it is safe for non-target animals in the environment.

The invention provides use of total saponins of panax japonicas in preparing a medicine for treating rheumatoid arthritis angiogenesis. Preferably, the medicine for relieving the rheumatoid arthritisangiogenesis takes effects through an HIF-1alpha / VEGF / ANG-1 signal pathway by the total saponins of panax japonicas. Results show that compared with a normal group, an thymus index, a spleen index, alymph node index, a posterior foot claw thickness and the foot swelling number of mice in a model group are obviously increased; a morphology shows obvious inflammatory cell infiltration, vascular proliferation and cartilage and bone destruction; an expression of an angiogenesis-related gene CD31 is increased and the number of immature blood vessels is obviously increased; and the contents of HIF-1alpha, VEGF and ANG-1 in serum are increased, and mRNA levels and protein expression levels of the HIF-1alpha, VEGF and ANG-1 are increased. After treatment by the total saponins of panax, the thymusindex, spleen index, lymph node index, foot posterior claw thickness and foot swelling number are obviously reduced; and the morphological inflammatory cell infiltration, vascular proliferation, cartilage and bone destruction are reduced.

The invention relates to a panax japonicus polysaccharide and a preparation method thereof. The method comprises the steps of performing aqueous extraction on the panax japonicus; removing protein; oxidizing, and performing alcohol precipitation, and the like. The panax japonicus polysaccharide has a remarkable adjuvant activity, wherein the 60 percent alcohol precipitated panax japonicus polysaccharide part has the strongest adjuvant activity, and has an intermediate viscosity-average molecular weight. Plant polysaccharides are widely distributed in the nature, and the application of the plant polysaccharides has a better advantage due to low toxicity and effectiveness, so that a novel thought and direction can be found for development of novel vaccine adjuvants.

The invention provides a selenium-rich panax japonicus standardized planting method. The selenium-rich panax japonicus standardized planting method is characterized by comprising the following steps of a, selecting seeds; b, cutting rhizomes into sections; c, processing the root sections; d, treating a culture medium; e, preparing a seedbed; f, performing seedling raising of the root sections; andg, performing post-seedling management. The selenium-rich panax japonicus standardized planting method achieves the aims that special traditional Chinese medicine resource panax japonicus in southernmountainous areas of the western Hubei Province is taken as an object, selenium-rich panax japonicus planting is systematically researched from the links of geographical conditions, climate factors,soil environment, atmospheric environment, irrigation water quality, improved variety selection, seed treatment, soil preparation and fertilization, sowing and transplanting, field management, diseaseand pest prevention and control, product harvesting, processing and packaging, storage and transportation, quality detection, label labeling and the like; technical regulations for standardized planting of the selenium-rich panax japonicas are formulated, and a standardized production mode is provided for developing the selenium-rich panax japonicas industry in the southern mountainous areas of the western Hubei Province; and a demonstration is provided for radiation popularization of the mode in the local area.

The invention provides a method for determining the content of panax japonicus saponin IVa in a throat clearing oral liquid, HPLC is used for detection, and chromatographic conditions are as follows:a chromatographic column C18 is adopted, the detection wavelength is 200-210 nm, the column temperature is 20-40 DEG C, the flow rate is 0.8-1 mL / min, and a mobile phase is subjected to isocratic elution with an acetonitrile-phosphoric acid aqueous solution. The method has the advantages of simplicity and convenience in sample treatment, high precision and accuracy, good stability, low cost and the like, and lays a foundation for quality control of the laryngopharynx clearing oral liquid.

The invention discloses a traditional Chinese medicine effective part composition for treating schizophrenia and a preparation method thereof. The traditional Chinese medicine effective part composition is prepared by the following raw materials in parts by weight: lotus seeds, cyathula officinalis, panax japonicus, musk deer glandular sac wall and castor bean. The traditional Chinese medicine effective part composition provided by the invention can be prepared into medicine for treating schizophrenia, and has effects of clearing heat and resolving phlegm, calming liver and stabilizing mind state, dissipating phlegm for resuscitation, restoring consciousness and calming mind, activating blood and dissolving stasis, nourishing Yin and purging fire, and warming kidney and strengthening spleen, can be used for treating schizophrenia obviously, and has the advantages of no toxicity or side effects, and high security.

The invention discloses a hypoglycemic active ingredient in panax japonicus, a hypoglycemic composition and application thereof. 1-12 compounds are separated from the panax japonicus, and that the 3 #compound and the 5-12 compounds have hypoglycemic activity is verified; the 1-12 compound composition and the 5-8 compound composition have hypoglycemic activity; and that panax japonicus total saponins and panax japonicus medicinal material extracts have hypoglycemic activity is verified. By means of in-vitro and in-vivo hypoglycemic experimental models, various hypoglycemic active ingredients in the panax japonicus, the hypoglycemic composition with the hypoglycemic advantage and related activity and application of the hypoglycemic active ingredient in the panax japonicus and the hypoglycemic composition with the hypoglycemic advantage in the aspect of diabetic renal complications are obtained through research. Hypoglycemic traditional Chinese medicine with small side effects and a goodeffect is screened out.

The present invention discloses a radix asparagi yin nourishing and dryness moistening tea substitute brewing potion and a preparation method thereof. The tea substitute brewing potion is prepared from the following raw materials in parts by weight: 45-55 parts of radix asparagi, 15-25 parts of fructus schisandrae chinensis, 15-25 parts of carapax trionycis, 15-25 parts of longan meat, 10-15 parts of rhizoma panacis japonici, 10-15 parts of liquorice, 10-15 parts of panax notoginseng flowers, 5-8 parts of big jujubes, 5-8 parts of cortex mori, 5-8 parts of eucalyptus globulus fruits, 5-8 parts of galium aparine, 5-8 parts of radix glehniae, 3-5 parts of xylitol, and 2-4 parts of white granulated sugar. The preparation method consists of the following main steps: 1, raw material pre-treating; 2, crushing and mixing; 3, mixed extract preparing; 4, concentrating and drying; and 5, brewing potion preparing. The radix asparagi yin nourishing and dryness moistening tea substitute brewing potion has functions of nourishing yin and moistening dryness, clearing away the lung-heat and promoting salivation, and supplementing and benefiting heart and spleen after being drunk for a long time, and has advantages of being health-care, fast in effects, purely natural, non-toxic, free of side effects, etc.

The invention discloses a traditional Chinese medicine composition for treating Alzheimer's disease. The traditional Chinese medicine composition is prepared from the following raw materials in partsby weight: 10-20 parts of potentilla anserine, 6-18 parts of herba cistanche, 9-21 parts of panax japonicus, 9-21 parts of psammosilene tunicoides, 9-15 parts of Chinese fevervine herb, 6-9 parts of clinopodium chinense and 3-9 parts of herba violae. The traditional Chinese medicine composition can be used for preventing and treating Alzheimer's disease, is a pure traditional Chinese medicine preparation, and is safe, low in toxicity, cheap and easy to prepare. According to the invention, pharmacological and pharmacodynamic experiments prove that compared with western medicines commonly used in the prior art, the treatment effect of the traditional Chinese medicine composition is obviously improved. The invention further provides a preparation process of the traditional Chinese medicine composition for treating the Alzheimer's disease. The preparation method is simple in process, beneficial to large-scale industrial production operation and small in pollution.

The invention provides an oral pharmaceutical intermediate of total compound rhizoma panacis iaponica saponins, wherein the raw materials include Rhizoma Panacis Japonica 20-65, curcuma longa 10-75, Momordica grosvenori 25-65. The preparing process consists of disintegrating Rhizoma Panacis Japonica, curcuma longa, Momordica grosvenori into 20-40 mesh fines, using ethanol or water as the dissolvent to extract active constituents in the herbs, combining the three coarse extracts, extracting saponins through CO2 hypercritical fluid abstraction technique.

The invention relates to a composition for strengthening an immune regulation function in a human body and applications thereof. The composition comprises effective components of panax japonicus saponin and panax japonicus polysaccharide or the effective components and an acceptable carrier on a health medicament, health food, health tea, health wine or a beverage. The composition has the function of improving the immune function of an immunocompromised mouse. In an animal model with a weak immune system caused by cyclophosphamide (Cy), the composition can enhance the spleen index of the immunocompromised mouse, enhance the proportions of CD<4+> to CD<8+> and B lymphocytes to NK cells, and increase the content of cell factors IL-2 and IFN-gamma. The composition enhances the medicament effect and the medical value of panax japonicus; therefore, the planting of medicinal materials and the development of medicaments can be promoted. The composition has better social and economic benefits.