Traditional Chinese medicine immunopotentiator for enhancing immune function of broiler chickens during growth
An immune enhancer and growth process technology, which is applied in the field of traditional Chinese veterinary medicine, can solve problems such as difficulty in exporting chicken meat, restricting the healthy and stable development of the broiler industry, and drug residues, so as to improve antibacterial and antiviral capabilities, reduce drug residues and pathogenic microorganisms, The effect of promoting immune function
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[0038] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine immunopotentiator, the dosage form of the traditional Chinese medicine immunopotentiator is an injection, and the method comprises:
[0039] The first step is to mix the blue cloth, bamboo ginseng, psoralen, Atractylodes macrocephala, sealwort, northern root, medlar, mistletoe, gynostemma pentaphyllum and ginseng in proportion, take 100g of the mixture and put it into the percolation cylinder, add 50 600g-800g of liquor at ℃~55℃, soaked at 25℃~35℃ for 20 hours to 30 hours, adjust the valve of the percolation cylinder, so that the liquor liquid drips out slowly, and the dripping speed is 2~4mL per minute , collect the dripping liquid to obtain 700mL-1L percolation liquid, concentrate, remove the white wine, dry and pulverize to obtain dry powder;
[0040] The second step is to mix the lower components in proportion, take 100g of the mixture, add 500g to 800g of wa...
Embodiment 1
[0078] The preparation of embodiment 1 decoction 1
[0079] Mix 50g of blue cloth, 45g of bamboo ginseng, 55g of psoralen, 45g of Atractylodes macrocephala, 50g of Polygonatum, 45g of Adenophora, 40g of medlar, 40g of mistletoe, 35g of Gynostemma pentaphyllum, and 20g of scorpion. Add 700g of white wine at 55°C to the drum, soak at 30°C for 25 hours, adjust the valve of the percolation drum to slowly drip out the liquor liquid at a rate of 3mL per minute, collect the dripping liquid, and obtain 700mL The percolate, concentrate, remove white wine, dry, crush to obtain dry powder, make platycodon 25g, pokeweed 30g, hawthorn 25g, yam 75g, honeysuckle 30g, Daxueteng 25g, Cnidium 40g, Artemisia annua 20g, cinnamon Mix 25g, Angelica 35g, Radix Radix 25g, Polygonum multiflorum 35g, Huangteng 25g, Licorice 30g, take 100g of the mixture, add 600g of water, boil for 4 hours, filter to obtain the first filtrate, add 200g of water to the filter residue, and boil for 2 hours again , filte...
Embodiment 2
[0080] Embodiment 2 toxicological experiment
[0081] Acute Toxicity Test
[0082] Select 20 Kunming mice, half and half female, body weight (20+2) g, provided by the Qingdao Experimental Animal Center, and the decoction prepared in Example 1 was fed to the mice. LD 50 , so the maximum tolerated dose was measured, with the administration volume of 1.4ml / 10g body weight, fed twice / d with an interval of 6h, observed for 7d after administration, and recorded the death of animals and symptoms of toxic and side effects. At the end of the experiment, the All animals were processed, dissected, and the lesions of the main organs and tissues were observed with the naked eye. After 2 times of gavage of 140g crude drug / kg, the animals moved, and no abnormalities were found in eating and drinking. The animals died after 7 days of observation, and no major organs and tissues were found in the autopsy with the naked eye. Therefore, the maximum dosage of traditional Chinese medicine granul...
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