36 results about "In situ visualization" patented technology

The present inventors have demonstrated that circulating auto-antibodies to cancer antigens hold promise as specific and sensitive biomarkers for the early detection of cancer. The present invention thus relates to methods of detecting cancer in a sample, comprising utilising a glycopeptide bait derived from human mucins with different cancer-associated O-glycans. Detected antibodies were demonstrated as glycopeptide specific, and it could be discriminated between e.g. colorectal cancer patients and healthy individuals. The inventors have also developed monoclonal antibodies based on the identified glycopeptides epitope baits, and demonstrated differential expression of the relevant target antigens. The invention thus, in a lock and key-based manner includes both glycopeptides and antibody tools for early detection of cancer, as well as methods of using the same for in situ visualisation and treatment of specific cancer types.

A dense volumetric grid coming from an oil / gas reservoir simulation output is translated into a compact representation that supports desired features such as interactive visualization, geometric continuity, color mapping and quad representation. A set of four control curves per layer results from processing the grid data, and a complete set of these 3-dimensional surfaces represents the complete volume data and can map reservoir properties of interest to analysts. The processing results yield a representation of reservoir simulation results which has reduced data storage requirements and permits quick performance interaction between reservoir analysts and the simulation data. The degree of reservoir grid compression can be selected according to the quality required, by adjusting for different thresholds, such as approximation error and level of detail. The processions results are of potential benefit in applications such as interactive rendering, data compression, and in-situ visualization of large-scale oil / gas reservoir simulations.

The invention belongs to the field of biological target positioning. In order to solve the problems that the boundaries of biological targets cannot be accurately identified and the biological targets cannot be marked in situ, a positioning method and system for in-situ visual positioning of biological targets are provided, which can It can accurately locate, identify, protect and determine the boundary of biological targets in real time and efficiently. Among them, the in-situ visual positioning method of biological targets includes collecting the fluorescence emitted by the fluorescent groups of biological targets in real time to form a fluorescent image of biological targets; processing the fluorescent images of biological targets to obtain images containing only biological targets and clear boundaries ; Adjust the optical path of the projection beam projected to the biological target to be coaxial with the fluorescent optical path emitted by the biological target, and project the image containing only the biological target and with clear boundaries in real time and in situ in equal proportions to the biological target area emitting fluorescence.

The invention provides a method for controlling the hydrophilic modification effect inside a micro-fluidic chip, and belongs to the technical field of micro-fluidic chip hydrophilic control. The method is based on the specific and selective recognition effects of aggregation induction luminescent molecules modified by two boric acid groups and PVA containing hydroxyls, the fluorescence visual imaging labeling is performed inside the micro-fluidic chip subjected to hydrophilic treatment; the inside fluorescence intensity and distribution condition can be subjected to measurement and control condition analysis through a fluorescence microscope or a laser co-focusing microscope. The method has the advantages that the in-situ visual control on the micro pore passages in the micro-fluidic chipis realized; the problem that the in-situ detection cannot be realized on the inside of the chip in the conventional measurement can be solved; the method belongs to a safe, nondestructive, fast and effective visual recognition method, and can be widely applied to the materials to realize the fast screening on the hydrophilic treatment effects.

The invention discloses an immunity probe based on a polymer luminous point and a preparing method and application thereof.The preparing method includes the steps that CN-PPV and PSMA are reacted, and a PDs aqueous solution is prepared and obtained; the PDs aqueous solution, PBS and EDC are mixed to be even to obtain mixed liquid A; the mixed liquid A and phosmet antibodies are mixed and reacted, and the immunity probe based on the polymer luminous point is obtained.The immunity probe can specifically recognize phosmet, and therefore the immunity probe can be used for quantitatively detecting phosmet and self-quantitatively or quantitatively detecting phosmet.The qualitative and self-quantitative detecting method is an in-situ visual detecting method; the quantitative detecting method is high in sensitivity and specificity, and high-sensitivity quantitative detection can be carried out.

The invention discloses an in-situ visualized analysis method of an organic bromine compound in soil. The in-situ visualized analysis method comprises the steps of (1) contaminating soil by an organic bromine compound, selecting water saturated microaggregate of the soil, slicing a frozen microaggregate particle to obtain a micro slicing sample and transferring the sample onto a glass slide, (2) analyzing the composition and microcell distribution of carbonic functional groups and clay minerals in the micro slicing sample of the soil to be detected by a synchrotron radiation Fourier transformation infrared micro-imaging technology, (3) analyzing the same area, detected by the synchrotron radiation Fourier transformation infrared micro-imaging technology, of the micro slicing sample by a hard X-ray micro-focusing fluorescent micro-imaging technology, and analyzing the distribution of a tracer element Br and other mineral elements in the area to be detected and the occurrence modes of other mineral elements and Br, and (4) respectively obtaining microcell distribution spectrograms of the carbonic functional groups, the clay minerals, Br and the other mineral elements in the analysis area, and analyzing the spectrograms to obtain the microcell distribution character, related influence factors and other information of the organic bromine pollutant in the soil.

The invention discloses an in-situ visualization system of X-ray fluoroscopy imaging and a calibration method thereof. By adopting the in-situ visualization system of X-ray fluoroscopy imaging and thecalibration method thereof, an acquired fluoroscopy image is projected on the surface of an imaging object according to an original X-ray path; an operator can acquire internal image information of the object simply by viewing fluoroscopy image projection on the surface of the object. According to the in-situ visualization system of X-ray fluoroscopy imaging and the calibration method thereof, acalibration device and a first optical tracking system tool are adopted to determine the position and main optical axis of an X-ray source, then, a second optical tracking system tool, a third opticaltracking system tool and a spatial position pick-up tool are adopted to determine the position and main optical axis of a projection reflection device, after the position and main optical axis of theX-ray source and the position and main optical axis of the projection reflection device are uniformly converted to the same coordinate system, aligning is conducted, the projection field angles are further unified, image directions are aligned, and therefore the calibration of the X-ray source and the calibration of the projection reflection device can be conveniently completed.