Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

36 results about "In situ visualization" patented technology

In-situ visualization method for cavitation behavior of fused brazing filler metal in solid liquid interface in ultrasonic-assisted brazing

The invention relates to an in-situ visualization method for the cavitation behavior of fused brazing filler metal in a solid liquid interface in ultrasonic-assisted brazing. The in-situ visualization method is suitable for the sizes of the brazing filler metal and base metal for synchrotron radiation imaging and the sandwiched coupled mode, and an ultrasonic field is applied through a high temperature-resistant ultrasonic vibration system capable of resisting 800 DEG C. The method comprises the steps of sample preparation; ultrasonic field application preparation; integral imaging equipment assembly; and visualization measurement of synchrotron radiation imaging of the cavitation behavior of the fused brazing filler metal. The method especially comprises the steps of ultrasonic field application in the high temperature environment, selection of the coupled mode of the sample base metal and the brazing filler metal and high temperature anti-oxidation treatment. The method is widely applied to the brazing filler metal of different temperatures and plays an important role in understanding and improving breaking oxidation films of the cavitation effect of ultrasonic-assisted brazing, promoting the moistening and spreading process of the brazing filler metal, revealing the acoustic-induced moistening physical mechanism of the brazing process of the brazing filler metal and the base metal (such as aluminum alloy and titanium alloy) and promoting industrial application of the ultrasonic-assisted brazing technology.
Owner:BEIJING UNIV OF TECH

In-situ visualization method for trajectory data based on stream data cube

The present invention discloses an in-situ visualization method for trajectory data based on a stream data cube, and defines a data structure suitable for stream data. For a certain quantity of arrival trajectory data streams, processing and update of data can be completed in a very short period of time, thereby implementing real-time processing of data. In addition to the use of conventional grid division, an administrative region division method with more practical significance is introduced. The administrative region division method allows a query processing result generated from the visualization method provided by the present invention to have more practical value. The method disclosed by the present invention has the features of short data processing time and quick data update.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

Method for early detection of cancer

The present inventors have demonstrated that circulating auto-antibodies to cancer antigens hold promise as specific and sensitive biomarkers for the early detection of cancer. The present invention thus relates to methods of detecting cancer in a sample, comprising utilising a glycopeptide bait derived from human mucins with different cancer-associated O-glycans. Detected antibodies were demonstrated as glycopeptide specific, and it could be discriminated between e.g. colorectal cancer patients and healthy individuals. The inventors have also developed monoclonal antibodies based on the identified glycopeptides epitope baits, and demonstrated differential expression of the relevant target antigens. The invention thus, in a lock and key-based manner includes both glycopeptides and antibody tools for early detection of cancer, as well as methods of using the same for in situ visualisation and treatment of specific cancer types.
Owner:WANDALL HANS H +2

In-situ visualization method of dispersity of inorganic filler in plastic

The invention discloses an in-situ visualization method of dispersity of an inorganic filler in plastic, belongs to the technical field of filler dispersity in plastic and relates to a method for special identification dyeing screening of an inorganic filler in plastic after film formation. Based on special identification of boronic acid-modified fluorescent molecules and surface hydroxyl of a layered filler, the inorganic filler in a press-molded plastic film is subjected to fluorescent labeling and through a fluorescence microscope or a confocal laser scanning microscope, the visualization result is measured and analyzed. The method is free of pre-modification or treatment on the inorganic filler, only utilizes immersion of any plastic film in boric acid fluorescent molecules, is an in-situ, non-destructive, rapid and effective visual identification method and can be widely used for effective screening of an inorganic filler in a composite material in the factory.
Owner:BEIJING UNIV OF CHEM TECH

In-situ visualization system of X-ray fluoroscopy imaging and calibration method thereof

The invention discloses an in-situ visualization system of X-ray fluoroscopy imaging and a calibration method thereof. By adopting the in-situ visualization system of X-ray fluoroscopy imaging and thecalibration method thereof, an acquired fluoroscopy image is projected on the surface of an imaging object according to an original X-ray path; an operator can acquire internal image information of the object simply by viewing fluoroscopy image projection on the surface of the object. According to the in-situ visualization system of X-ray fluoroscopy imaging and the calibration method thereof, acalibration device and a first optical tracking system tool are adopted to determine the position and main optical axis of an X-ray source, then, a second optical tracking system tool, a third opticaltracking system tool and a spatial position pick-up tool are adopted to determine the position and main optical axis of a projection reflection device, after the position and main optical axis of theX-ray source and the position and main optical axis of the projection reflection device are uniformly converted to the same coordinate system, aligning is conducted, the projection field angles are further unified, image directions are aligned, and therefore the calibration of the X-ray source and the calibration of the projection reflection device can be conveniently completed.
Owner:TSINGHUA UNIV

Molten salt electrochemical multifunctional in-situ characterization device and use method

The embodiment of the invention discloses a molten salt electrochemical multifunctional in-situ characterization device and a use method, and belongs to the technical field of high-temperature electrochemical analysis. The device provided by the invention can simultaneously support integration of in-situ Raman, in-situ optics and in-situ synchrotron radiation scanning, and can realize high-temperature melt structure analysis, in-situ visual display of the three-dimensional morphology of the electrode and deep and comprehensive understanding of the corresponding evolution process. The device is specifically composed of a vacuum heat preservation furnace body and a transparent electrolytic cell, and the vacuum heat preservation furnace body achieves three functions by designing a concave Raman corner objective lens inlet, an optical visualization window, a light supplementing window, an aluminum foil transmission window, a transparent quartz hearth, a two-section heating resistance wire and other systems. According to the transparent electrolytic bath, a furnace tube and a crucible of a conventional vertical resistance furnace are integrated, the crucible is connected with a rotating table at the bottom of a furnace body through machining, then the electrolytic bath rotates along with rotation of the rotating table in the testing process, and an electrode fault picture is obtained.
Owner:UNIV OF SCI & TECH BEIJING +1

In-situ visualization method for large-scale fluid simulation based on super computer

The invention discloses an in-situ visualization method for large-scale fluid simulation based on a super computer. The in-situ visualization method comprises the following steps: 1, obtaining grid data and flow field data xg and xw of a key time step from a simulation program of computational fluid mechanics; 2, completing the compression of the density rho, the X-momentum rho-u, the Y-momentum rho-v, the Z-momentum rho-w and the total energy p in the flow field data xw through a data compression technology; 3, transmitting the grid data xg and the flow field data xw to a visualization program and decompressing; 4, reasonably distributing the data to different nodes for visualization according to a data segmentation algorithm; and 5, combining the partitioning results obtained in the previous step, drawing a complete visualization result, and continuing the step 1 to obtain the related data of the next key time step, thereby realizing the in-situ visualization process of the large-scale fluid data.
Owner:TIANJIN UNIV

A molten salt electrochemical multifunctional in-situ characterization device and its application method

The embodiment of the present invention discloses a molten salt electrochemical multifunctional in-situ characterization device and its use method, which belong to the technical field of high temperature electrochemical analysis. The device of the invention can simultaneously support in-situ Raman, in-situ optical and in-situ synchrotron radiation scanning in one body, and can realize structural analysis of high-temperature melts, in-situ visualization of electrode three-dimensional morphology, and in-depth and comprehensive understanding of the corresponding evolution. process. The device is specifically composed of a vacuum insulation furnace body and a transparent electrolytic cell. The vacuum insulation furnace body is designed with a concave Raman corner objective lens entrance, an optical visualization window, a supplementary light window, an aluminum foil transmission window, a transparent quartz furnace, and two-stage heating. The resistance wire and other systems realize the above three functions; while the transparent electrolytic cell integrates the furnace tube and the crucible of the conventional vertical resistance furnace, and realizes the connection between the crucible and the rotary table at the bottom of the furnace through processing, and then realizes the test process. The electrolyzer rotates with the rotation of the turntable, and the tomographic picture of the electrode is obtained.
Owner:UNIV OF SCI & TECH BEIJING +1

An in situ visual analysis method for organic brominated compounds in soil

The invention discloses an in-situ visualized analysis method of an organic bromine compound in soil. The in-situ visualized analysis method comprises the steps of (1) contaminating soil by an organic bromine compound, selecting water saturated microaggregate of the soil, slicing a frozen microaggregate particle to obtain a micro slicing sample and transferring the sample onto a glass slide, (2) analyzing the composition and microcell distribution of carbonic functional groups and clay minerals in the micro slicing sample of the soil to be detected by a synchrotron radiation Fourier transformation infrared micro-imaging technology, (3) analyzing the same area, detected by the synchrotron radiation Fourier transformation infrared micro-imaging technology, of the micro slicing sample by a hard X-ray micro-focusing fluorescent micro-imaging technology, and analyzing the distribution of a tracer element Br and other mineral elements in the area to be detected and the occurrence modes of other mineral elements and Br, and (4) respectively obtaining microcell distribution spectrograms of the carbonic functional groups, the clay minerals, Br and the other mineral elements in the analysis area, and analyzing the spectrograms to obtain the microcell distribution character, related influence factors and other information of the organic bromine pollutant in the soil.
Owner:RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI

A core-shell nano-medicine for in situ visualized treatment of tumors and its preparation method

The invention relates to a core-shell nano-medicine for in situ visualized treatment of tumors, which belongs to the technical field of nano-medicine. The present invention adopts the nanoparticle formed by assembling the CpG OND labeled with the fluorescent probe and the polycationic compound as the inner core, and self-assembles the graphene quantum dot and photosensitizer copolymerization product modified by polydopamine surface on the inner core surface as the outer shell, and The MRI ion contrast agent is further chelated on the shell to form a core-shell nanomedicine. The nanomedicine of the present invention not only has excellent photodynamic / photothermal anticancer effect and good immune stimulation effect, but also can perform lesion imaging through MRI imaging contrast agent and fluorescent probe, has visualization characteristics, and realizes non-invasive real-time tracking of nano The distribution, absorption and metabolism of drugs can be further used for prognostic detection. The nano-medicine of the invention integrates combined therapy and multimodal imaging diagnosis functions, realizes the integration of tumor diagnosis and treatment, and has broad application prospects in the field of tumor diagnosis and treatment.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

An in-situ visualization system for X-ray fluoroscopic imaging and its calibration method

The invention discloses an in-situ visualization system of X-ray fluoroscopy imaging and a calibration method thereof. By adopting the in-situ visualization system of X-ray fluoroscopy imaging and thecalibration method thereof, an acquired fluoroscopy image is projected on the surface of an imaging object according to an original X-ray path; an operator can acquire internal image information of the object simply by viewing fluoroscopy image projection on the surface of the object. According to the in-situ visualization system of X-ray fluoroscopy imaging and the calibration method thereof, acalibration device and a first optical tracking system tool are adopted to determine the position and main optical axis of an X-ray source, then, a second optical tracking system tool, a third opticaltracking system tool and a spatial position pick-up tool are adopted to determine the position and main optical axis of a projection reflection device, after the position and main optical axis of theX-ray source and the position and main optical axis of the projection reflection device are uniformly converted to the same coordinate system, aligning is conducted, the projection field angles are further unified, image directions are aligned, and therefore the calibration of the X-ray source and the calibration of the projection reflection device can be conveniently completed.
Owner:TSINGHUA UNIV

In situ visualization of kinase activity

Kinases can be engineered to utilize an ATP analog that is not readily utilized by wild-type kinases by introducing a mutation in the ATP-binding pocket. However, application of this method has been limited by the membrane impermeability of the ATP analog. Provided herein are methods for in situ visualization of substrates of an analog-sensitive kinase, the method comprising a mild fixation step. Also provided herein are kits comprising a fixative, an ATP analog, and an agent for detecting the substrates modified by the ATP analog.
Owner:DANA FARBER CANCER INST INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products