34 results about "Hypotaurine" patented technology

Provided is a method for using low molecular weight compounds found in the body as a biomarker for diagnosing depression. Specifically, more than one compound selected from a group comprising the following are used: ADP-ribose, ATP, ADP, AMP, serotonin, tryptophan, kynurenine, SDMA (symmetrical dimethylarginine), threonine, glyceric acid, serine, N-acetylaspartic acid, glutamic acid, trigonelline, creatine, 2-methylserine, sphingosine, homovanillic acid, piperidine, sulfoxidized methionine, pipecolic acid, sphinganine, gamma-butyrobetaine, guanidinoacetic acid, isobutyric acid, creatinine, sarcosine, 3-methylbutyric acid, nicotinamide, betaine, ornithine, carnitine, ethanolamine, phosphoethanolamine, taurine, hypotaurine, aspartic acid, methionine, and tyrosine.

The invention discloses novel markers for predicting the efficacy of pemetrexed-platinum combined treatment on non-small cell lung cancer and its application. Specifically, the invention provides a set of the markers for predicting the efficacy of pemetrexed-platinum combined treatment on non-small cell lung cancer and its use in a product for predicting the efficacy of pemetrexed-platinum combined treatment on non-small cell lung cancer. The markers comprise hypotaurine, uridine, dodecanoyl carnitine, choline, dimethyl glycine, nicotinamide and hexadecanoyl carnitine. The markers and a modelwith the markers can predict the efficacy of the chemotherapy scheme before the patient undergoes chemotherapy and has sensitivity of 90.8% and specificity of 79.5%.

The invention discloses a fertilization solution for in-vitro fertilization of cattle and a use method thereof. The fertilization solution includes a SOF basal medium without inositol, and also includes the following additives: L-arginine, L-aspartic acid, L-carnitine, adrenaline, penicillamine, hypotaurine, and heparin. The fertilization solution of the invention can effectively ensure the in-vitro fertilization rate of the bovine embryo and the development quality of the fertilized embryo.

Provided is a method for using low molecular weight compounds found in the body as a biomarker for diagnosing depression. Specifically, more than one compound selected from a group comprising the following are used: ADP-ribose, ATP, ADP, AMP, serotonin, tryptophan, kynurenine, SDMA (symmetrical dimethylarginine), threonine, glyceric acid, serine, N-acetylaspartic acid, glutamic acid, trigonelline, creatine, 2-methylserine, sphingosine, homovanillic acid, piperidine, sulfoxidized methionine, pipecolic acid, sphinganine, gamma-butyrobetaine, guanidinoacetic acid, isobutyric acid, creatinine, sarcosine, 3-methylbutyric acid, nicotinamide, betaine, ornithine, carnitine, ethanolamine, phosphoethanolamine, taurine, hypotaurine, aspartic acid, methionine, and tyrosine.

The invention discloses novel markers for predicting the efficacy of pemetrexed-platinum combined treatment on non-small cell lung cancer and its application. Specifically, the invention provides a set of the markers for predicting the efficacy of pemetrexed-platinum combined treatment on non-small cell lung cancer and its use in a product for predicting the efficacy of pemetrexed-platinum combined treatment on non-small cell lung cancer. The markers comprise hypotaurine, uridine, dodecanoyl carnitine, choline, dimethyl glycine, nicotinamide and hexadecanoyl carnitine. The markers and a modelwith the markers can predict the efficacy of the chemotherapy scheme before the patient undergoes chemotherapy and has sensitivity of 90.8% and specificity of 79.5%.

The invention relates to a method for preventing and treating peach fruit brown rot. The steps of the method are as follows: the peach fruit is soaked in a hypotaurine solution with a concentration of 5-20 ppm for 0.5-2 h, treated, and then stored. The decay rate and plaque diameter of peach fruits treated with hypotaurine acid were significantly reduced, and the activities of defense-related enzymes (phenylalanine ammonia lyase and chitinase) were significantly increased, which significantly inhibited the peach fruit browning. rot. The method is safe, efficient and simple in process, can be widely applied to the storage of post-harvest peach fruits, and has broad market application prospects.

The invention belongs to the food technical field, and in particular relates to a method for preventing browning of fresh-cut Chinese yam. The method comprises the following steps: carrying out ultrasonic cleaning on Chinese yam, then peeling, slicing, soaking in a 100 ppm sodium hypochlorite solution, carrying out surface sterilization for 10 min, ventilating and draining off, soaking in an ascorbic acid and hypotaurine composite solution, and storing after treatment. The ascorbic acid and hypotaurine composite solution is selected for treating the fresh-cut Chinese yam, and the method has the advantages of simple operation, high safety, and no toxic residue on fruits and vegetables, allows the solution to be used repeatedly, and has quite high application values.

The present invention describes an approach to produce taurine or increase hypotaurine or taurine production in prokaryotes or eukaryotes. More particularly, the invention relates to genetic transformation of organisms with algal, microalgal or fungal genes that encode proteins that pool catalyze the conversion of sulfur-containing compounds such as sulfate or cysteine to taurine. The invention describes methods for the use of polynucleotides for cysteine dioxygenase-like (CDOL), sulfinoalanine decarboxylase-like (SADL), cysteine sulfate / decarboxylase or a portion of the cysteine synthetase / PLP decarboxylase (partCS / PLP-DC) polypeptide in bacteria, alga, yeast, or plants to produce taurine or increase hypotaurine or taurine. The preferred embodiment of the invention is in plants but other organisms may be used. Taurine production or increased levels of hypoataurine or taurine in plants could be used as nutraceutical, pharmaceutical, or therapeutic compounds or as a supplement in animal feed or for animal feed or as an enhancer for plant growth or yield.

The invention discloses a cloned embryo treatment solution, which is composed of BIX-01294 and PZM culture solution, the concentration of BIX-01294 in the PZM culture solution is 5nM-500nM; wherein, the PZM culture solution is composed of the following components: NaCl 3.156g; NaHCO 3 1.053g; KCl 0.373g; KH 2 SO 4 0.024g; MgSO 4 0.049g; calcium lactate 0.308g; pyruvate 0.011g; L-glutamic acid 0.073g; hypotaurine 0.273g; BME 10mL; MEM 5mL; penicillin 0.033g; 500mL. Using the cloned embryo treatment solution of the above technical scheme to culture and treat cloned embryos can achieve the following beneficial effects: (1) can significantly reduce the gene expression of cells SUV39H1, SETdb1, DNMT1 or DNMT3a; (2) can significantly down-regulate the H3K9me2 levels in 2cell and 4cell.

A method of inhibiting enzymatic browning in food involves the contacting of hypotaurine, a salt of hypotaurine or an equivalent of hypotaurine with the food. The hypotaurine can be provided from solution, an extract, or in solid form to a food that can loose its appeal to a consumer due to browning, such as cut fruits and vegetables, seafood, or a beverage. The antibrowning agent can be applied to the food by spraying, dusting, dipping, or dissolving, depending upon the form of the food to which the agent is added.

The invention discloses a fertilization solution for in-vitro fertilization of cattle and a use method thereof. The fertilization solution includes a SOF basal medium without inositol, and also includes the following additives: L-arginine, L-aspartic acid, L-carnitine, adrenaline, penicillamine, hypotaurine, and heparin. The fertilization solution of the invention can effectively ensure the in-vitro fertilization rate of the bovine embryo and the development quality of the fertilized embryo.