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52 results about "Hydroxybenzoates" patented technology

Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.

New method for synthesizing 3-cyclopropyl methoxy-4-(difluoromethoxy) benzoic acid

The invention relates to a new method for synthesizing 3-cyclopropyl methoxy-4-(difluoromethoxy) benzoic acid. The method is characterized by taking 3-nitro-4-hydroxybenzoic acid ester as the raw material to obtain the 3-cyclopropyl methoxy-4-(difluoromethoxy) benzoic acid through alkylation, reduction, diazotization, hydrolysis, alkylation, deprotection and the like. The 3-cyclopropyl methoxy-4-(difluoromethoxy) benzoic acid is a key intermediate for synthesizing the drug roflumilast.
Owner:NANJING SIMCERE MEDICAL LAB CO LTD +1

Polyolefin Photovoltaic Backsheet Comprising a Stabilized Polypropylene Layer

Polyolefin photovoltaic (PV) backsheets comprise a polypropylene layer stabilized with (A) at least one hindered amine with 2,2,6,6-tetraalkylpiperdine or 2,2,6,6 -tetraakylpiperazinone, either or both in combination with a triazine moiety, (B) a thioester, and, optionally, (C) at least one hindered hydroxybenzoate, and / or (D) an ortho hydroxyl triazine compound. These PV backsheets exhibit a low flame spread index of <100 without the use of FR agents, and the polypropylene layer exhibits good weatherability while providing the required long term heat aging performance necessary for PV modules.
Owner:DOW GLOBAL TECH LLC

Preparation of sterically hindered hydroxyphenylcarboxylic acid esters

A novel manufacturing process is described for producing hindered phenolic alkyl esters, which may be useful as antioxidants. This process simplifies catalyst neutralization and removal during the preparation of hindered phenolic esters. Compositions that comprise the hindered phenolic esters produced according to these methods are also described.
Owner:SI GROUP INC

Polyolefin Photovoltaic Backsheet Comprising a Stabilized Polypropylene Layer

Polyolefin photovoltaic (PV) backsheets comprise a polypropylene layer stabilized with (A) at least one hindered amine with 2,2,6,6-tetraalkylpiperdine or 2,2,6,6-tetraakylpiperazinone, either or both in combination with a triazine moiety, (B) a thioester, and, optionally, (C) at least one hindered hydroxybenzoate, and / or (D) an ortho hydroxyl triazine compound. These PV backsheets exhibit a low flame spread index of <100 without the use of FR agents, and the polypropylene layer exhibits good weatherability while providing the required long term heat aging performance necessary for PV modules.
Owner:DOW GLOBAL TECH LLC

Application of hydroxybenzoate acid and its analogue in the preparing process of medicine for preventing and treating virus infection

The invention relates to the use of hydroxybenzoate and analogues in preparing medicament for the prevention or treatment of viral infections, especially for preparing medicament for treating human and animal HBV, HPV and HSV.
Owner:SHENGHUA GUANGZHOU PHARMA SCI & TECH

2,3-dyhydroxyl parabens compound as well as preparation and application thereof

The invention provides a method for separating, extracting and preparing 2,3-dyhydroxyl parabens natural compound from traditional Chinese medicine gentian. The preparation method comprises the following steps of: pulverizing the traditional Chinese medicine gentian, extracting with carbinol, and carrying out suction filteration and concentration to obtain a methanol extract crude product, extracting and separating with 80 percent methanol water solution and normal hexane to obtain normal hexane layer crude sample; and separating the crude sample through a silica gel opening column and separating through an ODS opening column, and purifying by using a reverse HPLC to obtain a target compound. The naturally-separated 2,3-dyhydroxyl parabens compound used as a micromolecule compound represents obvious NGF mimics activity in an in-vitro screening model PC 12 cells for senile dementia, and can be applied to preparing medicaments for preventing neurodegenerative diseases of senile dementia and the like. A structure formula of the compound is shown as the following formula.
Owner:ZHEJIANG UNIV +1

Method for measuring p-hydroxybenzoate in cosmetics

The invention discloses a method for measuring p-hydroxybenzoate in cosmetics and relates to a method for measuring components in cosmetics. The method comprises the following steps: A, performing tested sample treatment, namely preparing the tested cosmetics into diluent; B, performing spectral measurement, namely B1, preparing a background spectrum set, B2, determining the standard spectrum of p-hydroxybenzoate, and B3, performing spectral measurement on the tested cosmetics; C, performing positive test and content measurement, namely C1, performing positive test, calculating an included angle between the merged matrix and the standard spectrum of p-hydroxybenzoate, when the included angle is larger than 0.15, the p-hydroxybenzoate is judged to be negative, and the spectrum of the tested cosmetics is recorded into the background spectrum database, and when the included angle is smaller than 0.1, the p-hydroxybenzoate is stored in the tested cosmetics, the sample is positive, and continuing, and C2 performing content measurement, namely deducing the standard spectrum of p-hydroxybenzoate from the spectrum of the tested cosmetics, thereby obtaining the actual content of the p-hydroxybenzoate. The method is high in analysis efficiency, low in operation strength, low in analysis cost, high in robustness and easy to popularize and use.
Owner:GUANGXI UNIVERSITY OF TECHNOLOGY

Oil agent for carbon-fiber-precursor acrylic fiber, oil agent composition for carbon-fiber-precursor acrylic fiber, oil-treatment-liquid for carbon-fiber-precursor acrylic fiber, and carbon-fiber-precursor acrylic fiber bundle

An oil for a carbon fiber precursor acrylic fiber including: a hydroxybenzoate ester (A) indicated by formula (1a); an amino-modified silicone (H) indicated by formula (3e); and an organic compound (X) which is compatible with the hydroxybenzoate ester (A), in which a residual mass rate R1 at 300° C. in thermal mass analysis in an air atmosphere is 70-100 mass % inclusive, and which is a liquid at 100° C., and a carbon fiber precursor acrylic fiber bundle to which the oil for a carbon fiber precursor acrylic fiber is adhered.
Owner:MITSUBISHI CHEM CORP

A detergent

A detergent including one or more neutral or overbased alkaline earth metal C10 to C40 hydrocarbyl substituted hydroxybenzoates, in which: (i) the one or more neutral or overbased alkaline earth metalC10 to C40 hydrocarbyl substituted hydroxybenzoates is or includes one or more C10 to C40 hydrocarb-1-yl substituted hydroxybenzoates; or, (ii) greater than 50 mole % of the one or more neutral or overbased alkaline earth metal C10 to C40 hydrocarbyl substituted hydroxybenzoates, based on the total number of moles of said C10 to C40 hydrocarbyl substituted hydroxybenzoates, is or includes one ormore C10 to C40 hydrocarb-2-yl substituted hydroxybenzoates.
Owner:INFINEUM INT LTD

Detergent

A detergent including one or more neutral or overbased alkaline earth metal C10 to C40 hydrocarbyl substituted hydroxybenzoates, in which:(i) the one or more neutral or overbased alkaline earth metal C10 to C40 hydrocarbyl substituted hydroxybenzoates is or includes one or more C10 to C40 hydrocarb-1-yl substituted hydroxybenzoates; or,(ii) greater than 50 mole % of the one or more neutral or overbased alkaline earth metal C10 to C40 hydrocarbyl substituted hydroxybenzoates, based on the total number of moles of said C10 to C40 hydrocarbyl substituted hydroxybenzoates, is or includes one or more C10 to C40 hydrocarb-2-yl substituted hydroxybenzoates.
Owner:INFINEUM INT LTD

Shelf-stable antimicrobial compositions

ActiveUS20200245615A1Extends antimicrobial efficacy of coatingReduce the populationBiocideAnimal repellantsBiotechnologyAmmonium compounds
A shelf-stable concentrated antimicrobial composition comprising at least one cyclic carboxylic acid and / or salt thereof in an amount from about 2 wt. % to about 4 wt. %; at least one anionic surfactant and / or salt thereof in an amount from about 22 wt. % to about 32 wt %; at least one non-surfactant strong acid (i.e. having a pKa less than about 2.3) in an amount from about 8 wt. % to about 18 wt. %; and at least one chelating agent in an amount from about 0.1 wt. % to about 2 wt. %. The composition retains at least 90% of its original antimicrobial efficacy after storage for at least five years at room temperature, and is substantially free of additional antimicrobial compounds including hydrogen peroxide, sources of hydrogen peroxide, essential oils, parabens, aldehydes, aldehyde releasing agents, phenols, antiseptic alcohols, biguanides, peroxycarboxylic acids, quaternary ammonium compounds, chlorine compounds, enzymes, and etchants. Also described are methods for using the composition to reduce the microbial load on a surface comprising, optionally, the step of diluting the composition with water and / or an organic solvent and, optionally, adding an additional antimicrobial compound, e.g. hydrogen peroxide, prior to use.
Owner:VIROX TECH

Peony essence stock solution mask containing graphene and preparation method thereof

The invention discloses a peony essence stock solution mask containing graphene and a preparation method thereof. The mask is composed of a component A and a component B. The component A is prepared from the components in parts by weight: 13-19 parts of peony flower stock solution, 9-15 parts of peony seed oil, 8-11 parts of glycerol, 7-12 parts of butanediol, 4-9 parts of an aloe extract, 3-5 parts of xanthan gum, 0.8-1.7 parts of hyaluronic acid, 0.5-0.8 part of hydroxyethyl cellulose, 0.03-0.06 part of hydroxybenzoate ester, and 55-72 parts of deionized water. The component B is graphene film cloth, and the component B is used as a carrier for carrying the component A. According to the peony essence stock solution mask containing graphene and the preparation method thereof, sufficient moisture is injected into skin, moisture in skin cuticle is prevented from being evaporated, and the graphene mask cloth of the component B has good compatibility, so that the loaded peony flower stock solution, the peony seed oil and the aloe extract are easy to absorb, the face is kept moist, the absorption of the skin is continuously promoted, and the skin is effectively improved.
Owner:厦门力嘉诚生物科技有限公司

Reduction of antimicrobial compound levels during product dispensing

A method for reducing antimicrobial compound levels in a liquid composition containing at least one antimicrobial compound. The method comprises contacting said liquid composition with a functionalized resin. Antimicrobial compounds that may be removed by this method include isothiazolin-3-ones, e.g., 2-methyl-4-isothiazolin-3-one; 5-chloro-2-methyl-4-isothiazolin-3-one; 2-n-octyl-4-isothiazolin-3-one; 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one; 1,2-benzisothiazolin-3-one and N-alkyl derivatives thereof, especially N-methyl and N-n-butyl; 2,2-dibromo-3-nitrilopropionamide (DBNPA); 2-bromo-2-nitropropanediol (BNPD); dithio-2,2′-bis(benzmethylamide) (DTBMA); hexetidine; chlorphenesin, C1-C4 alkyl-4-hydroxybenzoates (alkyl parabens); 3-iodopropynylbutylcarbamate (IPBC); formaldehyde releasers and mixtures thereof.
Owner:ROHM & HAAS CO

New-variety bean product formulation process and extraction method

The invention is applicable to the technical field of bean products and provides a new-variety bean product formulation process and an extraction method. The new-variety bean product formulation process involves a flavor additive and soybean milk, wherein a ratio of the flavor additive to the soybean milk is 1:9, and the flavor additive is prepared from anhydrous milk fat, red date juice, an emulsifier, diacetyl tartaric acid esters of mono(di)glycerides, octenyl succinic acid modified starch, trisodium phosphate, sodium para-hydroxybenzoate and water. By adoption of a formula of a bean product prepared from the flavor additive and the soybean milk, a unique flavor of the bean product is realized. Due to proportional adding of the anhydrous milk fat, the red date juice, the emulsifier, diacetyl tartaric acid esters of mono(di)glycerides, octenyl succinic acid modified starch, trisodium phosphate, sodium para-hydroxybenzoate and water into the flavor additive, the bean product is endowed with a red date and milk fat blended flavor and is safe to eat due to freeness of essence additives.
Owner:SHANGHAI QINGMEI GREEN FOOD

Low sulfur metal detergent-dispersants

A process for preparing alkylhydroxybenzoate detergent-dispersant additives having low sulfur content and high TBN is described. The alkali metal alkylhydroxylbenzoate, alkaline earth metal alkylhydroxybenzoate and overbased alkaline earth metal alkylhydroxybenzoate reaction products described have a sulfur content in the range of from about 0.1 to 1.2 wt % are effective anti-corrosive detergent-dispersant additives in lubricating oil compositions.
Owner:CHEVRON ORONITE CO LLC

Acne-removing and spot-fading mask and preparation method thereof

The invention provides an acne-removing and spot-fading mask and a preparation method thereof, belonging to the technical field of cosmetics. The acne-removing and spot-fading mask contains the following components: a Chinese traditional medicine extracting solution, peach blossom hydrolat, bitter melon juice, L-sodium pyrrolidonecarboxylate, polyoxyethylene sorbitan monolaurate, vitamin E, p-hydroxy-benzoate ester, apple polyphenol, plant essential oil and deionized water. The preparation method comprises the steps of firstly preparing the peach blossom hydrolat, the bitter melon juice and the Chinese traditional medicine extracting solution, mixing the peach blossom hydrolat, the bitter melon juice and the Chinese traditional medicine extracting solution with other auxiliary materials so as to obtain a mask liquid, and soaking mask paper into the mask liquid, so as to obtain the mask finished product. According to the acne-removing and spot-fading mask, natural plant essences are used as active components and are added with acne-removing and spot-fading medicinal materials for compatibility, so that the absorbability of the plant essences and the medicinal materials is effectively enhanced, and the mask has relatively good acne-removing, spot-fading and anti-aging effects.
Owner:ANHUI JINAIER ELECTRICAL APPLIANCE TECH

Hand disinfectant and preparation method thereof

The invention belongs to the technical field of disinfectant, and discloses a hand disinfectant and a preparation method thereof, and the specific method comprises the following steps: preparing raw material according to parts by weight; dissolving polyhexamethylene guanidine hydrochloride, Paraben, fatty alcohol-polyoxyethylene ether, hydroxypropyl methyl cellulose, peppermint oil and glycerol inpurified deionized water, and stirring to obtain a homogeneous solution; adding purified ionized water to a full amount, and carrying out constant volume and aging; inspecting the obtained intermediate product; if the product is qualified, performing potting and external packaging by using disinfectant plastic bottles and heads; and inspecting the finished product, and storing the qualified product in a finished product warehouse. The disinfectant disclosed by the invention has the excellent characteristics of broad sterilization spectrum, low effective concentration, high acting speed and easiness in dissolving in water, can be used at normal temperature, can inhibit bacteria for a long time, has no side effect and no corrosivity, and cleans and removes greasy dirt; the use is safe; theprice is moderate and transportation is convenient; and moreover, the disinfection has the effects of moistening skin and retaining water, and is high in sterilization capability and high in stability.
Owner:JILIN YUNFEI PHARMA CO LTD

Formula of nylon hose material

The invention provides a formula of a nylon hose material, wherein the nylon hose material at least takes a polyamide resin, a plasticizer and an impact modifier as production raw materials, the polyamide resin is obtained by copolymerizing short-chain odd-even nylon and short-chain even-even nylon, the plasticizer is one or a combination comprising a plurality of materials selected from higher alcohol, hydroxybenzoate, aromatic sulfonamide and phenol, and the impact modifier is one or a combination comprising a plurality of materials selected from polyolefin, an olefin copolymer and an elastomer. According to the invention, the nylon hose material has the characteristics of low price, high strength, good low-temperature flexibility, oil resistance, good dimensional stability, stable extrusion molding and the like compared with the long carbon chain nylon hose, and completely meets the requirements of the nylon hose for vehicles.
Owner:WUXI YINDA NYLON

Marine engine lubrication

A trunk piston marine engine lubricant comprises in respective minor amounts (A) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent system, and (B) a hydrocarbyl-subsituted succinic acid anhydride, preferably made by halogen- or radical-assisted fractionalization processes, where the ratio of succinic anhydride to hydrocarbyl chains is in the range of 1.4 to 4. The lubricant, when used to lubricate such an engine fuelled by heavy fuel oil, exhibits improved control of asphaltene precipitation and deposition on engine surfaces.
Owner:INFINEUM INT LTD

A kind of preparation method of tert-butyl substituted hydroxybenzoate

The invention discloses a preparation method of tert-butyl substituted hydroxybenzoate, which belongs to the field of fine chemical industry and aims to solve the problem of leaving tert-butyl group in the dehydration esterification reaction process of sulfonate catalyst. The method comprises the following steps: A, using the intermediate tert-butyl substituted hydroxybenzoate after the Kolbe-Kolbe-Schmidt reaction under the condition that N,N dimethylformamide is used as a solvent, The ester can be obtained by adding a halogenated hydrocarbon and a quaternary ammonium salt catalyst to react at a certain temperature, and the hydroxybenzoate is completely converted into a hydroxybenzoate by LC detection. B. After the reaction, add 10% dilute hydrochloric acid aqueous solution to acidify, then extract the product with toluene, combine the organic phase and add clay to reflux for decolorization and removal of impurities, add methanol to crystallize the crude product after removing the solvent under reduced pressure, and obtain a qualified product through methanol recrystallization. The invention utilizes the one-pot method of the Kolbe-Schmidt reaction intermediate to prepare tert-butyl substituted hydroxybenzoate, and the product has high purity and high yield.
Owner:GANSU RES INSTION OF CHEM IND GRICI

Medical ultrasonic coupling agent and preparation method thereof

The invention provides a medical ultrasonic coupling agent and a preparation method thereof, and belongs to the technical field of medical ultrasonic coupling agents. The provided ultrasonic coupling agent is prepared from the following preparation raw materials: 0.01-0.02% of valrocemide, 0.01-0.1% of dodecyl dimethyl benzyl ammonium chloride, 0.1-0.8% of p-hydroxybenzoate, 1.0-3.0% of isopropyl palmitate, 0.1-0.5% of fatty alcohol-polyoxyethylene ether, 0.1-0.6% of cross-linked polyacrylic resin, 5.0-10.0% of glycerol, 0.1-0.5% of triethanolamine and the balance water. The valrocemide has a new function of inhibiting escherichia coli, staphylococcus aureus and candida albicans. A novel medical ultrasonic coupling agent is prepared by using the valrocemide. The prepared medical ultrasonic coupling agent can realize broad-spectrum sterilization and high-efficiency sterilization, sterilizes and disinfects an ultrasonic probe in a whole ultrasonic diagnosis and treatment process, and effectively reduces a cross infection risk in an ultrasonic detection process.
Owner:山东科宏医疗科技有限公司
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