The present invention relates to a drinking water terminal sterilization water purifier, which comprises a pipe, a water inlet and a water outlet, wherein the water inlet and the water outlet are arranged on both ends of the pipe, a sterilization layer, a water purification layer and a heavy metal ion removing layer are sequentially stacked and are arranged inside the pipe along a direction from the water inlet to the water outlet, the sterilization layer comprises a high poly iodine resin, the water purification layer comprises active carbon particles and active carbon fibers, and the heavy metal ion removing layer comprises heavy metal nanosphere particles and a cation exchange resin. According to the present invention, all kinds of pathogenic bacteria and viruses damage harmful for human health in water can be instantly killed within 0.5 s through the high poly iodine resin in the sterilization layer, bacteria cannot grow on the high poly iodine resin so as not to generate secondary pollution, and the structure of the water purifier of the present invention is simple compared with the traditional water purifier in the case of the same sterilization effect; with the water purification layer, free iodine in the water can be neutralized and adsorbed, the residual chlorine and the organic pollutants in the water can be removed, and the taste of the water can be improved; with the heavy metal ion removing layer, the heavy metal ions dissolved in the water can be effectively removed, the hardness of the water can be reduced; and the drinking water terminal sterilization water purifier has characteristics of clogging resistance and long service life, and can be matched with other types of the filtration methods.