82 results about "Cetirizine Hydrochloride" patented technology

The invention relates to a cetirizine hydrochloride tablet. The cetirizine hydrochloride tablet comprises cetirizine hydrochloride lipidosome, a filler and a disintegrating agent. The cetirizine hydrochloride lipidosome comprises cetirizine hydrochloride, soya bean lecithin, cholesterol, vitamin E and Tween. The cetirizine hydrochloride tablet is advantaged by being rapid in dissolution, high in bioavailability, good in stability, simple in preparing process, suitable for industrial production, and the like.

The invention discloses a cetirizine hydrochloride tablet and a preparation method thereof, belonging to the field of chemical pharmaceutical preparations. The preparation is made of cetirizine hydrochloride into pellets, which are coated and prepared into tablets. The invention avoids The sticky punch is achieved, and the drug release is stable.

The invention belongs to the technical field of medicinal solid oral-taking preparation, relates to a cetirizine hydrochloride tablet and a preparation method thereof. The cetirizine hydrochloride tablet is prepared from the following raw materials and auxiliary materials of cetirizine hydrochloride, a filling agent, a flow aid, a bonding agent, a plasticizer, an opaquer, wherein the filling agentis prepared from microcrystalline cellulose and lactose; the flow aid is prepared from one or two of silicon dioxide, talcum powder and colloidal silicon dioxide; the lubricating agent is magnesium stearate; the bonding agent is prepared from one or two of hydroxypropyl methylcellulose, starch, dextrin or polyvinyl alcohol; the plasticizer is polyethylene glycol-400; and the opaquer is titanium dioxide. The product has high stability, can keep stable at high temperature and in a high-temperature environment; the product has high stability, can be stored for a longer time under the normal storage conditions, the shelf life of the product is prolonged, the product can be dissolved rapidly, bioavailability is high, as provided by external quality research, the product conforms to the regulation and standard, clinical bioequivalence can meet the requirement of the regulation. The invention further provides a preparation method, and the production prescription process is easy.

The invention provides cetirizine hydrochloride syrup. The syrup comprises cetirizine hydrochloride, sodium glutamate, xanthan gum, saccharose, a pH regulator, a flavoring agent and water, wherein the weight ratio of cetirizine hydrochloride to xanthan gum is 1:(1-10), preferably 1:5; the using amount of sodium glutamate accounts for 0.5-1.0 percent of the total weight of the syrup; the pH regulator is a disodium hydrogen phosphate-citric acid buffer solution; and the flavoring agent is aspartame, steviosin or sodium saccharin. The cetirizine hydrochloride syrup has excellent taste, stable property and simple preparation process.

A cetirizine hydrochloride tablet and a preparation method thereof, comprising dissolving cetirizine hydrochloride in water, adding an alkaline substance to form cetirizine base, causing its solubility to drop and precipitate, filtering, drying, and pulverizing to obtain The powder of cetirizine; cetirizine base, deoxycholic acid are dissolved in ethanol, and rotary evaporation removes ethanol, obtains cetirizine deoxycholic acid dispersion powder, then mixes with pharmaceutically available auxiliary materials, Tablet, obtained the cetirizine sheet that dissolves rapidly. The cetirizine tablet prepared by the invention dissolves rapidly, and has no corrosion to preparation production equipment such as dies.

The invention relates to a cetirizine hydrochloride solid preparation and a preparation method thereof, and belongs to the technical field of medicinal preparations. The solid preparation comprises cetirizine and a pH regulator, the pH regulator and the corresponding use amount of the pH regulator make the pH value of a solution obtained by dissolving the prepared solid preparation in water with the weight 10 times the weight of the solid preparation be 5.0-7.2, and the solid preparation meeting the above condition has good stability. The preparation method of the solid preparation has the advantages of simplicity in operation, low cost, and suitableness for industrial production.